| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BRAIDWELL LP | 2,894,513 | 3,452,447 | +557,934 | 2.05 | 2.02 | -0.03 | buy |
| MORGAN STANLEY | 1,025,471 | 1,487,747 | +462,276 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 199,973 | 477,800 | +277,827 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 106,219 | 382,621 | +276,402 | 0.01 | 0.02 | +0.01 | buy |
| MILLENNIUM MANAGEMENT LLC | 516,526 | 779,672 | +263,146 | 0.01 | 0.01 | +0.00 | buy |
| Rubric Capital Management LP | 2,419,103 | 2,619,103 | +200,000 | 0.99 | 0.94 | -0.05 | buy |
| Hudson Bay Capital Management LP | 90,000 | 225,000 | +135,000 | 0.02 | 0.03 | +0.01 | buy |
| ExodusPoint Capital Management, LP | 11,938 | 127,161 | +115,223 | 0.00 | 0.03 | +0.02 | buy |
| CITADEL ADVISORS LLC | 198,413 | 304,576 | +106,163 | 0.01 | 0.01 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 80,314 | 142,397 | +62,083 | 0.00 | 0.00 | +0.00 | buy |
| GLOBEFLEX CAPITAL L P | 27,940 | 88,596 | +60,656 | 0.07 | 0.15 | +0.08 | buy |
| ALGERT GLOBAL LLC | 91,159 | 135,814 | +44,655 | 0.06 | 0.06 | +0.00 | buy |
| OBERWEIS ASSET MANAGEMENT INC/ | 201,000 | 237,200 | +36,200 | 0.26 | 0.22 | -0.04 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 89,626 | 122,019 | +32,393 | 0.00 | 0.00 | +0.00 | buy |
| Jefferies Financial Group Inc. | 80,600 | 112,400 | +31,800 | 0.03 | 0.02 | -0.01 | buy |
| Qube Research & Technologies Ltd | 388,356 | 420,130 | +31,774 | 0.02 | 0.01 | -0.00 | buy |
| Bank of New York Mellon Corp | 91,669 | 122,051 | +30,382 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 31,696 | 61,482 | +29,786 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 742,307 | 771,607 | +29,300 | 0.00 | 0.00 | -0.00 | buy |
| NORTHERN TRUST CORP | 255,206 | 283,599 | +28,393 | 0.00 | 0.00 | -0.00 | buy |
| Verition Fund Management LLC | 26,784 | 54,728 | +27,944 | 0.00 | 0.01 | +0.00 | buy |
| PDT Partners, LLC | 37,242 | 64,917 | +27,675 | 0.08 | 0.11 | +0.03 | buy |
| Squarepoint Ops LLC | 0 | 26,808 | +26,808 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 704,712 | 729,579 | +24,867 | 0.00 | 0.00 | -0.00 | buy |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 75,169 | 99,632 | +24,463 | 0.05 | 0.05 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 0 | 23,002 | +23,002 | 0.00 | 0.00 | +0.00 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 47,717 | 69,813 | +22,096 | 0.00 | 0.00 | +0.00 | buy |
| SG Americas Securities, LLC | 0 | 17,970 | +17,970 | 0.00 | 0.00 | +0.00 | buy |
| State of Wyoming | 0 | 14,806 | +14,806 | 0.00 | 0.04 | +0.04 | buy |
| Allianz Asset Management GmbH | 8,800 | 23,500 | +14,700 | 0.00 | 0.00 | +0.00 | buy |
| Federation des caisses Desjardins du Quebec | 0 | 14,006 | +14,006 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 184,169 | 197,442 | +13,273 | 0.01 | 0.01 | -0.00 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 13,050 | +13,050 | 0.00 | 0.02 | +0.02 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 12,921 | +12,921 | 0.00 | 0.00 | +0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 44,229 | 56,691 | +12,462 | 0.00 | 0.00 | -0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 66,567 | 78,108 | +11,541 | 0.00 | 0.00 | -0.00 | buy |
| Parkman Healthcare Partners LLC | 755,244 | 765,453 | +10,209 | 2.41 | 2.02 | -0.39 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 482,976 | 492,630 | +9,654 | 0.00 | 0.00 | -0.00 | buy |
| UBS Group AG | 49,507 | 58,598 | +9,091 | 0.00 | 0.00 | -0.00 | buy |
| FMR LLC | 696,810 | 705,341 | +8,531 | 0.00 | 0.00 | -0.00 | buy |
| NORDEA INVESTMENT MANAGEMENT AB | 186,626 | 194,883 | +8,257 | 0.01 | 0.00 | -0.00 | buy |
| Bellevue Group AG | 0 | 8,100 | +8,100 | 0.00 | 0.00 | +0.00 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 7,553 | 15,487 | +7,934 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 13,639 | 21,102 | +7,463 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 64,629 | 71,896 | +7,267 | 0.00 | 0.00 | -0.00 | buy |
| STRS OHIO | 26,900 | 32,400 | +5,500 | 0.00 | 0.00 | -0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 211,118 | 215,772 | +4,654 | 0.00 | 0.00 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 3,908 | 8,483 | +4,575 | 0.00 | 0.00 | +0.00 | buy |
| PEREGRINE CAPITAL MANAGEMENT LLC | 239,682 | 244,043 | +4,361 | 0.18 | 0.14 | -0.04 | buy |
| Hennion & Walsh Asset Management, Inc. | 195,852 | 199,525 | +3,673 | 0.23 | 0.18 | -0.05 | buy |
| ProShare Advisors LLC | 9,450 | 12,807 | +3,357 | 0.00 | 0.00 | +0.00 | buy |
| LAZARD ASSET MANAGEMENT LLC | 0 | 3,098 | +3,098 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 12,230 | 15,111 | +2,881 | 0.00 | 0.00 | -0.00 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 17,118 | 19,988 | +2,870 | 0.00 | 0.00 | -0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 13,568 | 15,248 | +1,680 | 0.00 | 0.00 | -0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 20,461 | 21,841 | +1,380 | 0.00 | 0.00 | -0.00 | buy |
| MetLife Investment Management, LLC | 21,721 | 23,095 | +1,374 | 0.00 | 0.00 | -0.00 | buy |
| China Universal Asset Management Co., Ltd. | 7,810 | 8,814 | +1,004 | 0.02 | 0.02 | -0.01 | buy |
| MARTINGALE ASSET MANAGEMENT L P | 48,460 | 49,360 | +900 | 0.03 | 0.02 | -0.00 | buy |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 10,143 | 10,862 | +719 | 0.00 | 0.00 | -0.00 | buy |
| Sound View Wealth Advisors Group, LLC | 13,666 | 14,089 | +423 | 0.03 | 0.02 | -0.01 | buy |
| Truvestments Capital LLC | 539 | 829 | +290 | 0.00 | 0.00 | +0.00 | buy |
| Smartleaf Asset Management LLC | 0 | 214 | +214 | 0.00 | 0.00 | +0.00 | buy |
| MACQUARIE GROUP LTD | 500 | 655 | +155 | 0.00 | 0.00 | +0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 162 | 244 | +82 | 0.00 | 0.00 | -0.00 | buy |
| Van Hulzen Asset Management, LLC | 0 | 50 | +50 | 0.00 | 0.00 | +0.00 | buy |
| True Wealth Design, LLC | 166 | 212 | +46 | 0.00 | 0.00 | +0.00 | buy |
| IFP Advisors, Inc | 0 | 22 | +22 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 0 | 13 | +13 | 0.00 | 0.00 | +0.00 | buy |
| PNC FINANCIAL SERVICES GROUP, INC. | 4,776 | 4,785 | +9 | 0.00 | 0.00 | -0.00 | buy |
| Covestor Ltd | 11 | 13 | +2 | 0.00 | 0.00 | 0.00 | buy |
| NOMURA ASSET MANAGEMENT CO LTD | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| Ameritas Investment Partners, Inc. | 3,649 | 3,649 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 39,560 | 39,560 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TANG CAPITAL MANAGEMENT LLC | 628,609 | 628,609 | 0 | 1.12 | 0.82 | -0.30 | hold |
| BAKER BROS. ADVISORS LP | 2,818,323 | 2,818,323 | 0 | 0.73 | 0.60 | -0.13 | hold |
| JANUS HENDERSON GROUP PLC | 12,179 | 12,179 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Sterling Capital Management LLC | 38 | 38 | 0 | 0.00 | 0.00 | -0.00 | hold |
| HighVista Strategies LLC | 74,639 | 74,639 | 0 | 0.64 | 0.55 | -0.09 | hold |
| SIGNATUREFD, LLC | 943 | 943 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BROWN BROTHERS HARRIMAN & CO | 333 | 333 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Daiwa Securities Group Inc. | 139 | 139 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Arax Advisory Partners | 1 | 1 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Steward Partners Investment Advisory, LLC | 2,250 | 2,250 | 0 | 0.00 | 0.00 | -0.00 | hold |
| HHLR ADVISORS, LTD. | 1,582,635 | 1,582,635 | 0 | 0.87 | 1.08 | +0.22 | hold |
| Fortitude Family Office, LLC | 249 | 249 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Farther Finance Advisors, LLC | 199 | 199 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Creekmur Asset Management LLC | 95 | 95 | 0 | 0.00 | 0.00 | -0.00 | hold |
| M&T BANK CORP | 30,735 | 30,735 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Fisher Asset Management, LLC | 26,124 | 26,124 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AMALGAMATED BANK | 1,116 | 1,116 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NATIONAL BANK OF CANADA /FI/ | 501 | 494 | -7 | 0.00 | 0.00 | -0.00 | sell |
| Russell Investments Group, Ltd. | 57 | 25 | -32 | 0.00 | 0.00 | -0.00 | sell |
| Parkside Financial Bank & Trust | 45 | 0 | -45 | 0.00 | 0.00 | -0.00 | sell |
| Mirae Asset Global Investments Co., Ltd. | 1,469 | 1,385 | -84 | 0.00 | 0.00 | -0.00 | sell |
| Parallel Advisors, LLC | 521 | 416 | -105 | 0.00 | 0.00 | -0.00 | sell |
| Linden Thomas Advisory Services, LLC | 117,710 | 117,604 | -106 | 0.40 | 0.29 | -0.11 | sell |
| EARNED WEALTH ADVISORS, LLC | 116 | 0 | -116 | 0.00 | 0.00 | -0.00 | sell |
| CWM, LLC | 2,449 | 2,286 | -163 | 0.00 | 0.00 | -0.00 | sell |
| GAMMA Investing LLC | 841 | 670 | -171 | 0.00 | 0.00 | -0.00 | sell |