| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Deep Track Capital, LP | 14,218,903 | 17,849,482 | +3,630,579 | 1.25 | 0.90 | -0.36 | buy |
| ARMISTICE CAPITAL, LLC | 9,200,000 | 11,000,000 | +1,800,000 | 0.50 | 0.46 | -0.05 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 25,345,680 | 27,091,700 | +1,746,020 | 0.01 | 0.01 | -0.00 | buy |
| AXA S.A. | 1,824,685 | 3,126,167 | +1,301,482 | 0.01 | 0.02 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 618,942 | 1,584,125 | +965,183 | 0.00 | 0.00 | +0.00 | buy |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 2,864,632 | 3,608,490 | +743,858 | 0.01 | 0.01 | -0.00 | buy |
| Knott David M Jr | 0 | 420,000 | +420,000 | 0.00 | 0.31 | +0.31 | buy |
| TFG Asset Management GP Ltd | 8,250,000 | 8,600,000 | +350,000 | 6.26 | 4.28 | -1.98 | buy |
| JPMORGAN CHASE & CO | 1,071,533 | 1,410,104 | +338,571 | 0.00 | 0.00 | -0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 1,653,241 | 1,986,190 | +332,949 | 0.00 | 0.00 | -0.00 | buy |
| EDENTREE ASSET MANAGEMENT Ltd | 0 | 300,000 | +300,000 | 0.00 | 0.16 | +0.16 | buy |
| Eversept Partners, LP | 98,895 | 343,947 | +245,052 | 0.02 | 0.06 | +0.04 | buy |
| Laurion Capital Management LP | 3,189,547 | 3,369,248 | +179,701 | 0.47 | 0.40 | -0.07 | buy |
| Cetera Investment Advisers | 356,222 | 524,872 | +168,650 | 0.00 | 0.00 | -0.00 | buy |
| Vident Advisory, LLC | 0 | 155,504 | +155,504 | 0.00 | 0.00 | +0.00 | buy |
| Hennion & Walsh Asset Management, Inc. | 259,980 | 386,001 | +126,021 | 0.03 | 0.03 | -0.00 | buy |
| UBS Group AG | 200,232 | 316,227 | +115,995 | 0.00 | 0.00 | +0.00 | buy |
| NEOS Investment Management LLC | 0 | 110,428 | +110,428 | 0.00 | 0.00 | +0.00 | buy |
| TEMA ETFS LLC | 0 | 110,428 | +110,428 | 0.00 | 0.05 | +0.05 | buy |
| Virtus Investment Advisers, LLC | 0 | 61,027 | +61,027 | 0.00 | 0.03 | +0.03 | buy |
| Aubrey Capital Management Ltd | 84,822 | 119,998 | +35,176 | 0.08 | 0.08 | +0.00 | buy |
| EXCHANGE TRADED CONCEPTS, LLC | 41,866 | 69,993 | +28,127 | 0.00 | 0.00 | -0.00 | buy |
| Privium Fund Management B.V. | 231,674 | 251,674 | +20,000 | 0.12 | 0.10 | -0.02 | buy |
| Vanguard Personalized Indexing Management, LLC | 0 | 18,611 | +18,611 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 21,357 | 32,738 | +11,381 | 0.00 | 0.00 | +0.00 | buy |
| Mitsubishi UFJ Asset Management Co., Ltd. | 82,411 | 89,949 | +7,538 | 0.00 | 0.00 | -0.00 | buy |
| EverSource Wealth Advisors, LLC | 0 | 6,112 | +6,112 | 0.00 | 0.00 | +0.00 | buy |
| SG Americas Securities, LLC | 64,616 | 68,932 | +4,316 | 0.00 | 0.00 | -0.00 | buy |
| BARCLAYS PLC | 11,859 | 15,068 | +3,209 | 0.00 | 0.00 | -0.00 | buy |
| GAMMA Investing LLC | 4,530 | 6,857 | +2,327 | 0.00 | 0.00 | -0.00 | buy |
| Legal & General Group Plc | 297,736 | 299,836 | +2,100 | 0.00 | 0.00 | -0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 32,462 | 33,659 | +1,197 | 0.00 | 0.00 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 4,730 | 5,857 | +1,127 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 6,340 | 7,373 | +1,033 | 0.00 | 0.00 | -0.00 | buy |
| GF FUND MANAGEMENT CO. LTD. | 4,193 | 5,113 | +920 | 0.00 | 0.00 | -0.00 | buy |
| HighPoint Advisor Group LLC | 78,620 | 79,120 | +500 | 0.01 | 0.01 | -0.00 | buy |
| SBI Securities Co., Ltd. | 50 | 60 | +10 | 0.00 | 0.00 | -0.00 | buy |
| TRUST CO OF TOLEDO NA /OH/ | 36,265 | 36,265 | 0 | 0.01 | 0.01 | -0.00 | hold |
| GEODE CAPITAL MANAGEMENT, LLC | 86,256 | 86,256 | 0 | 0.00 | 0.00 | -0.00 | hold |
| DUMONT & BLAKE INVESTMENT ADVISORS LLC | 15,000 | 15,000 | 0 | 0.01 | 0.01 | -0.00 | hold |
| Rathbones Group PLC | 65,000 | 65,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Atle Fund Management AB | 479,644 | 479,644 | 0 | 0.50 | 0.33 | -0.17 | hold |
| DAFNA Capital Management LLC | 586,667 | 586,667 | 0 | 0.35 | 0.26 | -0.09 | hold |
| Blackstone Inc. | 20,485,611 | 20,485,611 | 0 | 0.23 | 0.14 | -0.09 | hold |
| Handelsbanken Fonder AB | 73,300 | 73,300 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Candriam S.C.A. | 3,191,401 | 3,191,401 | 0 | 0.04 | 0.03 | -0.01 | hold |
| Avoro Capital Advisors LLC | 9,910,642 | 9,910,642 | 0 | 0.33 | 0.24 | -0.09 | hold |
| QUADRANT CAPITAL GROUP LLC | 3,024 | 3,024 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Alphabet Inc. | 698,262 | 698,262 | 0 | 0.10 | 0.07 | -0.03 | hold |
| OSAIC HOLDINGS, INC. | 21,724 | 21,724 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Close Asset Management Ltd | 500 | 500 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Syncona Portfolio Ltd | 16,640,720 | 16,640,720 | 0 | 73.83 | 97.81 | +23.98 | hold |
| Frazier Life Sciences Management, L.P. | 4,623,324 | 4,623,324 | 0 | 0.45 | 0.33 | -0.12 | hold |
| HERBST GROUP, LLC | 25,000 | 25,000 | 0 | 0.04 | 0.03 | -0.01 | hold |
| Byrne Asset Management LLC | 250 | 250 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Marex Group plc | 12,500 | 12,500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Erste Asset Management GmbH | 195,000 | 195,000 | 0 | 0.01 | 0.00 | -0.00 | hold |
| HUNTINGTON NATIONAL BANK | 1 | 1 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CALDWELL SUTTER CAPITAL, INC. | 500 | 500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| Clearstead Advisors, LLC | 91,107 | 91,107 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BLAIR WILLIAM & CO/IL | 12,794 | 12,794 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STATE STREET CORP | 256,530 | 256,515 | -15 | 0.00 | 0.00 | -0.00 | sell |
| Caitong International Asset Management Co., Ltd | 1,172 | 1,127 | -45 | 0.00 | 0.00 | -0.00 | sell |
| Cornerstone Planning Group LLC | 100 | 0 | -100 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 3,330 | 3,163 | -167 | 0.00 | 0.00 | -0.00 | sell |
| LAZARD ASSET MANAGEMENT LLC | 178 | 0 | -178 | 0.00 | 0.00 | 0.00 | sell |
| Brooklyn Investment Group | 377 | 0 | -377 | 0.00 | 0.00 | -0.00 | sell |
| Truvestments Capital LLC | 500 | 0 | -500 | 0.00 | 0.00 | -0.00 | sell |
| Daiwa Securities Group Inc. | 23,743 | 22,927 | -816 | 0.00 | 0.00 | -0.00 | sell |
| Mirae Asset Global Investments Co., Ltd. | 6,655 | 5,790 | -865 | 0.00 | 0.00 | -0.00 | sell |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 28,333 | 27,130 | -1,203 | 0.00 | 0.00 | -0.00 | sell |
| US BANCORP \DE\ | 2,102 | 64 | -2,038 | 0.00 | 0.00 | -0.00 | sell |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 2,079 | 0 | -2,079 | 0.00 | 0.00 | -0.00 | sell |
| China Universal Asset Management Co., Ltd. | 42,345 | 40,200 | -2,145 | 0.01 | 0.01 | -0.00 | sell |
| R Squared Ltd | 4,680 | 0 | -4,680 | 0.01 | 0.00 | -0.01 | sell |
| WELLS FARGO & COMPANY/MN | 266,315 | 261,146 | -5,169 | 0.00 | 0.00 | -0.00 | sell |
| WEALTH EFFECTS LLC | 42,800 | 36,300 | -6,500 | 0.04 | 0.02 | -0.01 | sell |
| Vontobel Holding Ltd. | 147,419 | 138,783 | -8,636 | 0.00 | 0.00 | -0.00 | sell |
| Avanza Fonder AB | 31,770 | 21,276 | -10,494 | 0.00 | 0.00 | -0.00 | sell |
| UNITED BANK | 10,850 | 0 | -10,850 | 0.00 | 0.00 | -0.00 | sell |
| EWA, LLC | 15,280 | 0 | -15,280 | 0.01 | 0.00 | -0.01 | sell |
| ALPS ADVISORS INC | 215,190 | 199,709 | -15,481 | 0.00 | 0.00 | -0.00 | sell |
| SIMPLEX TRADING, LLC | 18,057 | 0 | -18,057 | 0.00 | 0.00 | -0.00 | sell |
| Arkadios Wealth Advisors | 20,000 | 0 | -20,000 | 0.00 | 0.00 | -0.00 | sell |
| VIRTUS ADVISERS, LLC | 26,429 | 0 | -26,429 | 0.03 | 0.00 | -0.03 | sell |
| OMERS ADMINISTRATION Corp | 36,300 | 0 | -36,300 | 0.00 | 0.00 | -0.00 | sell |
| LPL Financial LLC | 36,725 | 0 | -36,725 | 0.00 | 0.00 | -0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 2,939,241 | 2,900,186 | -39,055 | 0.00 | 0.00 | -0.00 | sell |
| Bellevue Group AG | 41,500 | 0 | -41,500 | 0.00 | 0.00 | -0.00 | sell |
| Perpetual Ltd | 1,279,620 | 1,223,743 | -55,877 | 0.04 | 0.02 | -0.01 | sell |
| ACADIAN ASSET MANAGEMENT LLC | 56,273 | 0 | -56,273 | 0.00 | 0.00 | -0.00 | sell |
| Bayesian Capital Management, LP | 65,000 | 0 | -65,000 | 0.02 | 0.00 | -0.02 | sell |
| Jump Financial, LLC | 72,396 | 0 | -72,396 | 0.00 | 0.00 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 126,230 | 50,411 | -75,819 | 0.00 | 0.00 | -0.00 | sell |
| Walleye Capital LLC | 75,940 | 0 | -75,940 | 0.00 | 0.00 | -0.00 | sell |
| Qube Research & Technologies Ltd | 158,685 | 51,188 | -107,497 | 0.00 | 0.00 | -0.00 | sell |
| CITADEL ADVISORS LLC | 324,002 | 188,908 | -135,094 | 0.00 | 0.00 | -0.00 | sell |
| MARSHALL WACE, LLP | 757,535 | 619,913 | -137,622 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA ADVISERS, LP | 333,400 | 164,700 | -168,700 | 0.00 | 0.00 | -0.00 | sell |