| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| MAK CAPITAL ONE LLC | 0 | 16,955,098 | +16,955,098 | 0.00 | 6.82 | +6.82 | buy |
| ARMISTICE CAPITAL, LLC | 11,000,000 | 12,000,000 | +1,000,000 | 0.46 | 1.04 | +0.58 | buy |
| BANK OF AMERICA CORP /DE/ | 0 | 975,135 | +975,135 | 0.00 | 0.00 | +0.00 | buy |
| TFG Asset Management GP Ltd | 8,600,000 | 9,500,000 | +900,000 | 4.28 | 3.91 | -0.37 | buy |
| CITADEL ADVISORS LLC | 188,908 | 1,004,378 | +815,470 | 0.00 | 0.00 | +0.00 | buy |
| Atle Fund Management AB | 479,644 | 1,105,461 | +625,817 | 0.33 | 1.08 | +0.75 | buy |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0 | 565,000 | +565,000 | 0.00 | 0.04 | +0.04 | buy |
| Aubrey Capital Management Ltd | 119,998 | 452,200 | +332,202 | 0.08 | 0.38 | +0.30 | buy |
| Diametric Capital, LP | 0 | 279,688 | +279,688 | 0.00 | 0.34 | +0.34 | buy |
| Eversept Partners, LP | 343,947 | 610,231 | +266,284 | 0.06 | 0.14 | +0.08 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0 | 220,569 | +220,569 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 0 | 168,254 | +168,254 | 0.00 | 0.02 | +0.02 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 1,584,125 | 1,751,200 | +167,075 | 0.00 | 0.01 | +0.00 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 0 | 109,427 | +109,427 | 0.00 | 0.02 | +0.02 | buy |
| Cubist Systematic Strategies, LLC | 0 | 107,758 | +107,758 | 0.00 | 0.00 | +0.00 | buy |
| TUDOR INVESTMENT CORP ET AL | 0 | 106,653 | +106,653 | 0.00 | 0.00 | +0.00 | buy |
| Quadrature Capital Ltd | 0 | 96,216 | +96,216 | 0.00 | 0.00 | +0.00 | buy |
| Cetera Investment Advisers | 524,872 | 617,172 | +92,300 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 86,256 | 164,314 | +78,058 | 0.00 | 0.00 | +0.00 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 27,091,700 | 27,147,035 | +55,335 | 0.01 | 0.01 | +0.00 | buy |
| Privium Fund Management B.V. | 251,674 | 294,142 | +42,468 | 0.10 | 0.15 | +0.04 | buy |
| Hennion & Walsh Asset Management, Inc. | 386,001 | 428,318 | +42,317 | 0.03 | 0.04 | +0.01 | buy |
| UBS Group AG | 316,227 | 353,667 | +37,440 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asset Management, L.P. | 34,645 | 71,400 | +36,755 | 0.00 | 0.00 | +0.00 | buy |
| Avanza Fonder AB | 21,276 | 53,522 | +32,246 | 0.00 | 0.00 | +0.00 | buy |
| Clearstead Advisors, LLC | 91,107 | 121,107 | +30,000 | 0.00 | 0.00 | +0.00 | buy |
| HighPoint Advisor Group LLC | 79,120 | 108,620 | +29,500 | 0.01 | 0.01 | +0.01 | buy |
| FOREFRONT WEALTH MANAGEMENT INC. | 0 | 26,870 | +26,870 | 0.00 | 0.05 | +0.05 | buy |
| Delaney Dennis R | 0 | 24,000 | +24,000 | 0.00 | 0.03 | +0.03 | buy |
| R Squared Ltd | 0 | 21,746 | +21,746 | 0.00 | 0.03 | +0.03 | buy |
| Mariner, LLC | 0 | 18,947 | +18,947 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 0 | 13,507 | +13,507 | 0.00 | 0.00 | +0.00 | buy |
| Vanguard Personalized Indexing Management, LLC | 18,611 | 30,432 | +11,821 | 0.00 | 0.00 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 27,130 | 38,419 | +11,289 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA SECURITIES, LLC | 0 | 10,001 | +10,001 | 0.00 | 0.00 | +0.00 | buy |
| NEOS Investment Management LLC | 110,428 | 120,388 | +9,960 | 0.00 | 0.00 | +0.00 | buy |
| TEMA ETFS LLC | 110,428 | 120,388 | +9,960 | 0.05 | 0.07 | +0.02 | buy |
| RHUMBLINE ADVISERS | 7,373 | 16,709 | +9,336 | 0.00 | 0.00 | +0.00 | buy |
| GAMMA Investing LLC | 6,857 | 10,045 | +3,188 | 0.00 | 0.00 | +0.00 | buy |
| Close Asset Management Ltd | 500 | 3,300 | +2,800 | 0.00 | 0.00 | +0.00 | buy |
| SIMPLEX TRADING, LLC | 0 | 2,512 | +2,512 | 0.00 | 0.00 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 5,790 | 7,746 | +1,956 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 15,068 | 15,800 | +732 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 3,163 | 3,822 | +659 | 0.00 | 0.00 | +0.00 | buy |
| China Universal Asset Management Co., Ltd. | 40,200 | 40,273 | +73 | 0.01 | 0.01 | +0.00 | buy |
| Allworth Financial LP | 0 | 50 | +50 | 0.00 | 0.00 | +0.00 | buy |
| PRINCIPAL SECURITIES, INC. | 0 | 37 | +37 | 0.00 | 0.00 | +0.00 | buy |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 3,608,490 | 3,608,490 | 0 | 0.01 | 0.01 | +0.00 | hold |
| DUMONT & BLAKE INVESTMENT ADVISORS LLC | 15,000 | 15,000 | 0 | 0.01 | 0.01 | +0.00 | hold |
| Rathbones Group PLC | 65,000 | 65,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Blackstone Inc. | 20,485,611 | 20,485,611 | 0 | 0.14 | 0.21 | +0.07 | hold |
| Alphabet Inc. | 698,262 | 698,262 | 0 | 0.07 | 0.07 | +0.01 | hold |
| Syncona Portfolio Ltd | 16,640,720 | 16,640,720 | 0 | 97.81 | 98.24 | +0.43 | hold |
| Affinity Asset Advisors, LLC | 3,045,000 | 3,045,000 | 0 | 0.74 | 1.03 | +0.29 | hold |
| Frazier Life Sciences Management, L.P. | 4,623,324 | 4,623,324 | 0 | 0.33 | 0.42 | +0.09 | hold |
| HERBST GROUP, LLC | 25,000 | 25,000 | 0 | 0.03 | 0.03 | +0.01 | hold |
| EDENTREE ASSET MANAGEMENT Ltd | 300,000 | 300,000 | 0 | 0.16 | 0.19 | +0.03 | hold |
| Marex Group plc | 12,500 | 12,500 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Erste Asset Management GmbH | 195,000 | 195,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| GF FUND MANAGEMENT CO. LTD. | 5,113 | 5,113 | 0 | 0.00 | 0.00 | +0.00 | hold |
| HUNTINGTON NATIONAL BANK | 1 | 1 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CALDWELL SUTTER CAPITAL, INC. | 500 | 500 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| AXA S.A. | 3,126,167 | 3,126,167 | 0 | 0.02 | 0.02 | +0.00 | hold |
| SBI Securities Co., Ltd. | 60 | 50 | -10 | 0.00 | 0.00 | +0.00 | sell |
| Byrne Asset Management LLC | 250 | 225 | -25 | 0.00 | 0.00 | +0.00 | sell |
| US BANCORP \DE\ | 64 | 0 | -64 | 0.00 | 0.00 | -0.00 | sell |
| Caitong International Asset Management Co., Ltd | 1,127 | 0 | -1,127 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 5,857 | 4,277 | -1,580 | 0.00 | 0.00 | -0.00 | sell |
| QUADRANT CAPITAL GROUP LLC | 3,024 | 0 | -3,024 | 0.00 | 0.00 | -0.00 | sell |
| Invesco Ltd. | 32,738 | 29,636 | -3,102 | 0.00 | 0.00 | +0.00 | sell |
| EverSource Wealth Advisors, LLC | 6,112 | 1,564 | -4,548 | 0.00 | 0.00 | -0.00 | sell |
| WELLS FARGO & COMPANY/MN | 261,146 | 253,102 | -8,044 | 0.00 | 0.00 | +0.00 | sell |
| MAI Capital Management | 33,866 | 21,234 | -12,632 | 0.00 | 0.00 | -0.00 | sell |
| BLAIR WILLIAM & CO/IL | 12,794 | 0 | -12,794 | 0.00 | 0.00 | -0.00 | sell |
| Virtus Investment Advisers, LLC | 61,027 | 43,736 | -17,291 | 0.03 | 0.03 | +0.01 | sell |
| OSAIC HOLDINGS, INC. | 21,724 | 0 | -21,724 | 0.00 | 0.00 | -0.00 | sell |
| Daiwa Securities Group Inc. | 22,927 | 575 | -22,352 | 0.00 | 0.00 | -0.00 | sell |
| WEALTH EFFECTS LLC | 36,300 | 13,500 | -22,800 | 0.02 | 0.01 | -0.01 | sell |
| GOLDMAN SACHS GROUP INC | 50,411 | 24,106 | -26,305 | 0.00 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 33,659 | 2,722 | -30,937 | 0.00 | 0.00 | -0.00 | sell |
| SG Americas Securities, LLC | 68,932 | 36,544 | -32,388 | 0.00 | 0.00 | -0.00 | sell |
| TRUST CO OF TOLEDO NA /OH/ | 36,265 | 0 | -36,265 | 0.01 | 0.00 | -0.01 | sell |
| Qube Research & Technologies Ltd | 51,188 | 0 | -51,188 | 0.00 | 0.00 | -0.00 | sell |
| Laurion Capital Management LP | 3,369,248 | 3,316,626 | -52,622 | 0.40 | 0.87 | +0.47 | sell |
| ALPS ADVISORS INC | 199,709 | 143,614 | -56,095 | 0.00 | 0.00 | +0.00 | sell |
| EXCHANGE TRADED CONCEPTS, LLC | 69,993 | 0 | -69,993 | 0.00 | 0.00 | -0.00 | sell |
| Handelsbanken Fonder AB | 73,300 | 0 | -73,300 | 0.00 | 0.00 | -0.00 | sell |
| Mitsubishi UFJ Asset Management Co., Ltd. | 89,949 | 0 | -89,949 | 0.00 | 0.00 | -0.00 | sell |
| Vontobel Holding Ltd. | 138,783 | 0 | -138,783 | 0.00 | 0.00 | -0.00 | sell |
| Knott David M Jr | 420,000 | 270,000 | -150,000 | 0.31 | 0.28 | -0.03 | sell |
| Vident Advisory, LLC | 155,504 | 0 | -155,504 | 0.00 | 0.00 | -0.00 | sell |
| DAFNA Capital Management LLC | 586,667 | 425,616 | -161,051 | 0.26 | 0.27 | +0.01 | sell |
| TWO SIGMA ADVISERS, LP | 164,700 | 0 | -164,700 | 0.00 | 0.00 | -0.00 | sell |
| STATE STREET CORP | 256,515 | 68,317 | -188,198 | 0.00 | 0.00 | -0.00 | sell |
| BIT Capital GmbH | 199,359 | 0 | -199,359 | 0.04 | 0.00 | -0.04 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 2,900,186 | 2,694,202 | -205,984 | 0.00 | 0.00 | +0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 395,443 | 146,797 | -248,646 | 0.00 | 0.00 | -0.00 | sell |
| Legal & General Group Plc | 299,836 | 0 | -299,836 | 0.00 | 0.00 | -0.00 | sell |
| Perpetual Ltd | 1,223,743 | 829,090 | -394,653 | 0.02 | 0.02 | -0.00 | sell |