| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| DEERFIELD MANAGEMENT COMPANY, L.P. | 0 | 6,110,098 | +6,110,098 | 0.00 | 0.05 | +0.05 | buy |
| ORBIMED ADVISORS LLC | 4,517,589 | 4,517,589 | 0 | 0.03 | 0.04 | +0.01 | hold |
| JOHNSON & JOHNSON | 2,133,402 | 1,923,201 | -210,201 | 0.01 | 0.02 | +0.01 | sell |
| 8VC GP I, LLC | 1,086,191 | 1,086,191 | 0 | 0.31 | 0.62 | +0.31 | hold |
| RENAISSANCE TECHNOLOGIES LLC | 110,294 | 80,600 | -29,694 | 0.00 | 0.00 | +0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 0 | 19,763 | +19,763 | 0.00 | 0.00 | +0.00 | buy |
| Jump Financial, LLC | 0 | 19,209 | +19,209 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 14,531 | 10,188 | -4,343 | 0.00 | 0.00 | -0.00 | sell |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 49,500 | 0 | -49,500 | 0.00 | 0.00 | -0.00 | sell |
| MMCAP International Inc. SPC | 96,805 | 0 | -96,805 | 0.00 | 0.00 | -0.00 | sell |
| Walleye Trading LLC | 10,422 | 0 | -10,422 | 0.00 | 0.00 | -0.00 | sell |
| Walleye Capital LLC | 21,056 | 0 | -21,056 | 0.00 | 0.00 | -0.00 | sell |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |