| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Nantahala Capital Management, LLC | 1,730,600 | 2,493,309 | +762,709 | 0.09 | 0.11 | +0.03 | buy |
| Alyeska Investment Group, L.P. | 865,400 | 1,590,738 | +725,338 | 0.00 | 0.00 | +0.00 | buy |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 1,787,610 | 2,494,108 | +706,498 | 0.02 | 0.03 | +0.00 | buy |
| AIGH Capital Management LLC | 865,400 | 1,566,944 | +701,544 | 0.24 | 0.45 | +0.21 | buy |
| ADAR1 Capital Management, LLC | 0 | 299,598 | +299,598 | 0.00 | 0.03 | +0.03 | buy |
| Allostery Investments LP | 643,833 | 940,629 | +296,796 | 0.92 | 0.75 | -0.17 | buy |
| Warberg Asset Management LLC | 0 | 99,616 | +99,616 | 0.00 | 0.02 | +0.02 | buy |
| TWO SIGMA SECURITIES, LLC | 0 | 15,950 | +15,950 | 0.00 | 0.00 | +0.00 | buy |
| Carolina Wealth Advisors, LLC | 0 | 159 | +159 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 429,990 | 430,000 | +10 | 0.00 | 0.00 | -0.00 | buy |
| ORBIMED ADVISORS LLC | 1,787,767 | 1,787,767 | 0 | 0.03 | 0.02 | -0.00 | hold |
| DAFNA Capital Management LLC | 401,136 | 401,136 | 0 | 0.07 | 0.06 | -0.01 | hold |
| BOOTHBAY FUND MANAGEMENT, LLC | 237,376 | 237,376 | 0 | 0.01 | 0.00 | -0.00 | hold |
| Ikarian Capital, LLC | 892,976 | 892,976 | 0 | 0.19 | 0.16 | -0.02 | hold |
| SBI Securities Co., Ltd. | 300 | 300 | 0 | 0.00 | 0.00 | -0.00 | hold |
| JOHNSON & JOHNSON | 96,866 | 96,866 | 0 | 0.02 | 0.02 | -0.00 | hold |
| BARCLAYS PLC | 25,000 | 25,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| CLEAR STREET LLC | 2,463 | 2,363 | -100 | 0.00 | 0.00 | -0.00 | sell |
| Carolina Wealth Advisors, LLC | 159 | 0 | -159 | 0.00 | 0.00 | -0.00 | sell |
| HEIGHTS CAPITAL MANAGEMENT, INC | 258,492 | 14,497 | -243,995 | 0.09 | 0.00 | -0.09 | sell |