| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| JOHNSON & JOHNSON | 0 | 3,636,363 | +3,636,363 | 0.00 | 1.22 | +1.22 | buy |
| MILLENNIUM MANAGEMENT LLC | 196,779 | 459,966 | +263,187 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 13,243 | 181,202 | +167,959 | 0.00 | 0.00 | +0.00 | buy |
| Almitas Capital LLC | 0 | 100,876 | +100,876 | 0.00 | 0.06 | +0.06 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 94,484 | +94,484 | 0.00 | 0.01 | +0.01 | buy |
| Centiva Capital, LP | 0 | 71,700 | +71,700 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 0 | 54,201 | +54,201 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 0 | 53,253 | +53,253 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | 45,531 | +45,531 | 0.00 | 0.01 | +0.01 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 31,294 | 67,695 | +36,401 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 24,971 | +24,971 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 0 | 24,500 | +24,500 | 0.00 | 0.00 | +0.00 | buy |
| Schonfeld Strategic Advisors LLC | 0 | 18,800 | +18,800 | 0.00 | 0.00 | +0.00 | buy |
| HSBC HOLDINGS PLC | 0 | 17,531 | +17,531 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 6,348 | 20,751 | +14,403 | 0.00 | 0.00 | +0.00 | buy |
| Point72 (DIFC) Ltd | 0 | 13,933 | +13,933 | 0.00 | 0.00 | +0.00 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 0 | 13,800 | +13,800 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 26,015 | 37,800 | +11,785 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 2,279,618 | 2,290,058 | +10,440 | 0.00 | 0.00 | -0.00 | buy |
| TUDOR INVESTMENT CORP ET AL | 0 | 10,367 | +10,367 | 0.00 | 0.00 | +0.00 | buy |
| Catalyst Funds Management Pty Ltd | 0 | 7,800 | +7,800 | 0.00 | 0.00 | +0.00 | buy |
| Hartford Financial Management Inc. | 0 | 6,500 | +6,500 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 8,119 | 13,179 | +5,060 | 0.00 | 0.00 | -0.00 | buy |
| FEDERATED HERMES, INC. | 1,738 | 6,217 | +4,479 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 4,045 | 6,390 | +2,345 | 0.00 | 0.00 | +0.00 | buy |
| Cubist Systematic Strategies, LLC | 0 | 1,822 | +1,822 | 0.00 | 0.00 | +0.00 | buy |
| MACQUARIE GROUP LTD | 0 | 1,574 | +1,574 | 0.00 | 0.00 | +0.00 | buy |
| CAPTRUST FINANCIAL ADVISORS | 10,031 | 10,094 | +63 | 0.00 | 0.00 | -0.00 | buy |
| CWM, LLC | 0 | 36 | +36 | 0.00 | 0.00 | 0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 10 | 25 | +15 | 0.00 | 0.00 | +0.00 | buy |
| VIKING GLOBAL INVESTORS LP | 4,194,777 | 4,194,777 | 0 | 0.03 | 0.02 | -0.01 | hold |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 96,200 | 96,200 | 0 | 0.00 | 0.00 | -0.00 | hold |
| HARBOURVEST PARTNERS LLC | 21,877 | 21,877 | 0 | 0.02 | 0.02 | -0.00 | hold |
| Mariner, LLC | 405,631 | 405,631 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Laurion Capital Management LP | 783,391 | 783,391 | 0 | 0.04 | 0.03 | -0.01 | hold |
| Utah Retirement Systems | 13,240 | 13,240 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Northeast Financial Consultants Inc | 22,088 | 22,088 | 0 | 0.00 | 0.00 | -0.00 | hold |
| New Leaf Venture Partners, L.L.C. | 3,301,603 | 3,301,603 | 0 | 5.35 | 5.38 | +0.03 | hold |
| Aberdeen Group plc | 1,727,067 | 1,727,067 | 0 | 0.01 | 0.00 | -0.00 | hold |
| 5AM Venture Management, LLC | 3,630,724 | 3,630,724 | 0 | 1.50 | 1.09 | -0.42 | hold |
| Pivotal bioVenture Partners Investment Advisor LLC | 2,404,644 | 2,404,644 | 0 | 2.86 | 2.48 | -0.38 | hold |
| Canaan Partners XI LLC | 2,059,712 | 2,059,712 | 0 | 4.20 | 3.34 | -0.86 | hold |
| TPG GP A, LLC | 3,028,414 | 3,028,414 | 0 | 0.11 | 0.06 | -0.04 | hold |
| Farther Finance Advisors, LLC | 9 | 9 | 0 | 0.00 | 0.00 | -0.00 | hold |
| DIMENSIONAL FUND ADVISORS LP | 21,203 | 21,203 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Avior Wealth Management, LLC | 5 | 0 | -5 | 0.00 | 0.00 | -0.00 | sell |
| Capital Advisors, Ltd. LLC | 203 | 82 | -121 | 0.00 | 0.00 | 0.00 | sell |
| RESOURCES MANAGEMENT CORP /CT/ /ADV | 250 | 0 | -250 | 0.00 | 0.00 | 0.00 | sell |
| AMALGAMATED BANK | 559 | 0 | -559 | 0.00 | 0.00 | -0.00 | sell |
| STRS OHIO | 1,600 | 0 | -1,600 | 0.00 | 0.00 | -0.00 | sell |
| Ameritas Investment Partners, Inc. | 2,525 | 0 | -2,525 | 0.00 | 0.00 | -0.00 | sell |
| Legal & General Group Plc | 2,946 | 0 | -2,946 | 0.00 | 0.00 | -0.00 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 3,472 | 0 | -3,472 | 0.00 | 0.00 | -0.00 | sell |
| Squarepoint Ops LLC | 36,425 | 31,917 | -4,508 | 0.00 | 0.00 | -0.00 | sell |
| ADAR1 Capital Management, LLC | 17,942 | 11,200 | -6,742 | 0.01 | 0.00 | -0.01 | sell |
| MERCER GLOBAL ADVISORS INC /ADV | 10,000 | 0 | -10,000 | 0.00 | 0.00 | -0.00 | sell |
| NEW YORK STATE COMMON RETIREMENT FUND | 10,467 | 267 | -10,200 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 37,020 | 26,539 | -10,481 | 0.00 | 0.00 | -0.00 | sell |
| SG Americas Securities, LLC | 10,565 | 0 | -10,565 | 0.00 | 0.00 | -0.00 | sell |
| CAPSTONE INVESTMENT ADVISORS, LLC | 10,900 | 0 | -10,900 | 0.00 | 0.00 | -0.00 | sell |
| AMERICAN INTERNATIONAL GROUP, INC. | 15,067 | 0 | -15,067 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 244,765 | 228,915 | -15,850 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 22,791 | 0 | -22,791 | 0.01 | 0.00 | -0.01 | sell |
| MARSHALL WACE, LLP | 29,032 | 0 | -29,032 | 0.00 | 0.00 | -0.00 | sell |
| RHUMBLINE ADVISERS | 39,954 | 10,372 | -29,582 | 0.00 | 0.00 | -0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 77,018 | 0 | -77,018 | 0.00 | 0.00 | -0.00 | sell |
| Bank of New York Mellon Corp | 90,316 | 0 | -90,316 | 0.00 | 0.00 | -0.00 | sell |
| CITADEL ADVISORS LLC | 399,662 | 280,000 | -119,662 | 0.00 | 0.00 | -0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 488,100 | 340,700 | -147,400 | 0.00 | 0.00 | -0.00 | sell |
| VANGUARD GROUP INC | 1,076,771 | 857,896 | -218,875 | 0.00 | 0.00 | -0.00 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 519,648 | 220,006 | -299,642 | 0.00 | 0.00 | -0.00 | sell |
| Blue Owl Capital Holdings LP | 350,240 | 0 | -350,240 | 0.13 | 0.00 | -0.13 | sell |
| STATE STREET CORP | 513,718 | 65,222 | -448,496 | 0.00 | 0.00 | -0.00 | sell |