| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ADAR1 Capital Management, LLC | 20,535 | 926,352 | +905,817 | 0.01 | 0.70 | +0.69 | buy |
| Rangeley Capital, LLC | 30,130 | 104,850 | +74,720 | 0.29 | 1.56 | +1.27 | buy |
| CITADEL ADVISORS LLC | 0 | 72,200 | +72,200 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 0 | 47,423 | +47,423 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 156,527 | 199,907 | +43,380 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 25,657 | +25,657 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 0 | 16,619 | +16,619 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 0 | 12,996 | +12,996 | 0.00 | 0.00 | +0.00 | buy |
| Quadrature Capital Ltd | 0 | 12,995 | +12,995 | 0.00 | 0.00 | +0.00 | buy |
| BlackRock, Inc. | 17,486 | 30,332 | +12,846 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 11,226 | 21,497 | +10,271 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 793,451 | 794,720 | +1,269 | 0.00 | 0.00 | +0.00 | buy |
| MERCER GLOBAL ADVISORS INC /ADV | 0 | 1,250 | +1,250 | 0.00 | 0.00 | +0.00 | buy |
| Caitong International Asset Management Co., Ltd | 0 | 434 | +434 | 0.00 | 0.00 | +0.00 | buy |
| Truvestments Capital LLC | 0 | 129 | +129 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 0 | 31 | +31 | 0.00 | 0.00 | +0.00 | buy |
| Allworth Financial LP | 0 | 6 | +6 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 0 | 3 | +3 | 0.00 | 0.00 | +0.00 | buy |
| VIKING GLOBAL INVESTORS LP | 524,347 | 524,347 | 0 | 0.01 | 0.02 | +0.01 | hold |
| BNP PARIBAS FINANCIAL MARKETS | 120 | 120 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Hartford Financial Management Inc. | 812 | 812 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Mariner, LLC | 50,566 | 50,566 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Pivotal bioVenture Partners Investment Advisor LLC | 300,579 | 300,579 | 0 | 0.96 | 1.56 | +0.60 | hold |
| TPG GP A, LLC | 378,551 | 378,551 | 0 | 0.09 | 0.12 | +0.03 | hold |
| Fortitude Family Office, LLC | 53 | 53 | 0 | 0.00 | 0.00 | +0.00 | hold |
| DIMENSIONAL FUND ADVISORS LP | 11,280 | 11,280 | 0 | 0.00 | 0.00 | +0.00 | hold |
| SBI Securities Co., Ltd. | 524 | 506 | -18 | 0.00 | 0.00 | +0.00 | sell |
| Tower Research Capital LLC (TRC) | 907 | 0 | -907 | 0.00 | 0.00 | -0.00 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 35,425 | 32,047 | -3,378 | 0.00 | 0.00 | +0.00 | sell |
| ACADIAN ASSET MANAGEMENT LLC | 10,433 | 0 | -10,433 | 0.00 | 0.00 | -0.00 | sell |
| GTS SECURITIES LLC | 22,016 | 0 | -22,016 | 0.01 | 0.00 | -0.01 | sell |
| DELTEC ASSET MANAGEMENT LLC | 33,750 | 0 | -33,750 | 0.06 | 0.00 | -0.06 | sell |
| Almitas Capital LLC | 191,206 | 120,682 | -70,524 | 0.39 | 0.46 | +0.08 | sell |
| AJU IB Investment Co., Ltd. | 94,334 | 0 | -94,334 | 2.77 | 0.00 | -2.77 | sell |
| Nantahala Capital Management, LLC | 300,635 | 188,422 | -112,213 | 0.17 | 0.18 | +0.01 | sell |
| JOHNSON & JOHNSON | 152,901 | 0 | -152,901 | 0.21 | 0.00 | -0.21 | sell |
| 5AM Venture Management, LLC | 291,788 | 0 | -291,788 | 0.73 | 0.00 | -0.73 | sell |
| Laurion Capital Management LP | 302,756 | 0 | -302,756 | 0.25 | 0.00 | -0.25 | sell |
| BALYASNY ASSET MANAGEMENT L.P. | 376,573 | 0 | -376,573 | 0.01 | 0.00 | -0.01 | sell |
| Cormorant Asset Management, LP | 400,000 | 0 | -400,000 | 0.18 | 0.00 | -0.18 | sell |