| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| VIKING GLOBAL INVESTORS LP | 4,194,777 | 4,194,777 | 0 | 0.01 | 0.01 | +0.00 | hold |
| JOHNSON & JOHNSON | 3,636,363 | 3,636,363 | 0 | 0.36 | 0.45 | +0.09 | hold |
| 5AM Venture Management, LLC | 3,630,724 | 3,630,724 | 0 | 0.66 | 0.78 | +0.12 | hold |
| TPG GP A, LLC | 3,028,414 | 3,028,414 | 0 | 0.08 | 0.08 | -0.00 | hold |
| Pivotal bioVenture Partners Investment Advisor LLC | 2,404,644 | 2,404,644 | 0 | 0.69 | 0.64 | -0.06 | hold |
| FMR LLC | 1,694,388 | 1,694,388 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Almitas Capital LLC | 1,538,727 | 1,529,653 | -9,074 | 0.18 | 0.23 | +0.06 | sell |
| VANGUARD GROUP INC | 999,627 | 1,016,249 | +16,622 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 714,800 | 835,692 | +120,892 | 0.00 | 0.00 | +0.00 | buy |
| AJU IB Investment Co., Ltd. | 754,678 | 754,678 | 0 | 0.33 | 18.18 | +17.85 | hold |
| Canaan Partners XI LLC | 450,000 | 450,000 | 0 | 0.22 | 0.23 | +0.01 | hold |
| Mariner, LLC | 404,546 | 404,546 | 0 | 0.00 | 0.00 | +0.00 | hold |
| GEODE CAPITAL MANAGEMENT, LLC | 245,009 | 248,005 | +2,996 | 0.00 | 0.00 | +0.00 | buy |
| BlackRock, Inc. | 141,663 | 141,663 | 0 | 0.00 | 0.00 | +0.00 | hold |
| XTX Topco Ltd | 59,108 | 97,313 | +38,205 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 90,247 | 83,480 | -6,767 | 0.00 | 0.00 | +0.00 | sell |
| STATE STREET CORP | 62,072 | 62,072 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Rangeley Capital, LLC | 83,007 | 40,000 | -43,007 | 0.04 | 0.02 | -0.02 | sell |
| NORTHERN TRUST CORP | 38,124 | 38,124 | 0 | 0.00 | 0.00 | +0.00 | hold |
| TWO SIGMA INVESTMENTS, LP | 21,453 | 37,000 | +15,547 | 0.00 | 0.00 | +0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 38,400 | 29,100 | -9,300 | 0.00 | 0.00 | +0.00 | sell |
| Virtu Financial LLC | 39,303 | 27,132 | -12,171 | 0.00 | 0.00 | -0.00 | sell |
| HRT FINANCIAL LP | 32,224 | 21,387 | -10,837 | 0.00 | 0.00 | -0.00 | sell |
| OneDigital Investment Advisors LLC | 20,000 | 20,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| GSA CAPITAL PARTNERS LLP | 0 | 19,303 | +19,303 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 0 | 19,300 | +19,300 | 0.00 | 0.00 | +0.00 | buy |
| Ground Swell Capital, LLC | 0 | 15,399 | +15,399 | 0.00 | 0.02 | +0.02 | buy |
| GREAT VALLEY ADVISOR GROUP, INC. | 15,000 | 15,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Utah Retirement Systems | 13,240 | 13,240 | 0 | 0.00 | 0.00 | +0.00 | hold |
| ACT Advisors, LLC. | 0 | 13,153 | +13,153 | 0.00 | 0.00 | +0.00 | buy |
| CAPTRUST FINANCIAL ADVISORS | 0 | 10,000 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| MERCER GLOBAL ADVISORS INC /ADV | 10,000 | 10,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Hartford Financial Management Inc. | 6,500 | 6,500 | 0 | 0.00 | 0.00 | +0.00 | hold |
| BARCLAYS PLC | 5,719 | 5,719 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Tower Research Capital LLC (TRC) | 10,181 | 4,524 | -5,657 | 0.00 | 0.00 | -0.00 | sell |
| SBI Securities Co., Ltd. | 4,248 | 4,248 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CITIGROUP INC | 9,895 | 3,932 | -5,963 | 0.00 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 980 | 980 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Allworth Financial LP | 50 | 50 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CAPTRUST FINANCIAL ADVISORS | 10,000 | 0 | -10,000 | 0.00 | 0.00 | -0.00 | sell |
| Rockefeller Capital Management L.P. | 550 | 0 | -550 | 0.00 | 0.00 | -0.00 | sell |