| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Siren, L.L.C. | 0 | 5,850,000 | +5,850,000 | 0.00 | 0.36 | +0.36 | buy |
| Soleus Capital Management, L.P. | 6,325,000 | 10,875,000 | +4,550,000 | 0.55 | 0.95 | +0.40 | buy |
| Saturn V Capital Management LP | 0 | 3,856,799 | +3,856,799 | 0.00 | 1.45 | +1.45 | buy |
| Blackstone Inc. | 2,638,276 | 5,938,276 | +3,300,000 | 0.02 | 0.05 | +0.03 | buy |
| ADAR1 Capital Management, LLC | 5,247,603 | 8,063,949 | +2,816,346 | 0.84 | 1.24 | +0.39 | buy |
| Fairmount Funds Management LLC | 6,125,000 | 8,625,000 | +2,500,000 | 0.89 | 1.35 | +0.45 | buy |
| Sands Capital Alternatives, LLC | 10,950,000 | 13,018,965 | +2,068,965 | 3.89 | 5.15 | +1.26 | buy |
| Integral Health Asset Management, LLC | 0 | 1,750,000 | +1,750,000 | 0.00 | 0.18 | +0.18 | buy |
| Nantahala Capital Management, LLC | 2,190,000 | 3,929,292 | +1,739,292 | 0.22 | 0.48 | +0.26 | buy |
| Stonepine Capital Management, LLC | 735,019 | 2,348,147 | +1,613,128 | 0.97 | 3.81 | +2.84 | buy |
| AMERIPRISE FINANCIAL INC | 0 | 1,376,395 | +1,376,395 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 3,273,339 | 4,558,604 | +1,285,265 | 0.00 | 0.00 | +0.00 | buy |
| CITADEL ADVISORS LLC | 0 | 1,243,630 | +1,243,630 | 0.00 | 0.00 | +0.00 | buy |
| Exome Asset Management LLC | 0 | 600,000 | +600,000 | 0.00 | 0.61 | +0.61 | buy |
| BlackRock, Inc. | 3,075,186 | 3,305,574 | +230,388 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 0 | 169,850 | +169,850 | 0.00 | 0.00 | +0.00 | buy |
| Persistent Asset Partners Ltd | 0 | 93,430 | +93,430 | 0.00 | 0.09 | +0.09 | buy |
| WELLS FARGO & COMPANY/MN | 0 | 67,833 | +67,833 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 507,749 | 554,849 | +47,100 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 0 | 20,298 | +20,298 | 0.00 | 0.00 | +0.00 | buy |
| Scientech Research LLC | 0 | 15,977 | +15,977 | 0.00 | 0.02 | +0.02 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,112,574 | 1,128,239 | +15,665 | 0.00 | 0.00 | +0.00 | buy |
| CAXTON CORP | 16,393 | 28,453 | +12,060 | 0.12 | 1.36 | +1.25 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 0 | 11,400 | +11,400 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 10,570 | +10,570 | 0.00 | 0.00 | +0.00 | buy |
| Virtu Financial LLC | 13,446 | 22,869 | +9,423 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 85,578 | 94,795 | +9,217 | 0.00 | 0.00 | +0.00 | buy |
| Pinnacle Wealth Planning Services, Inc. | 0 | 5,400 | +5,400 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 7,702 | 10,814 | +3,112 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 902 | 3,286 | +2,384 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 27,963 | 28,875 | +912 | 0.00 | 0.00 | +0.00 | buy |
| ProShare Advisors LLC | 10,341 | 11,046 | +705 | 0.00 | 0.00 | +0.00 | buy |
| Focus Partners Advisor Solutions, LLC | 10,708 | 10,719 | +11 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 0 | 4 | +4 | 0.00 | 0.00 | +0.00 | buy |
| Allworth Financial LP | 0 | 1 | +1 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 6,174 | 6,174 | 0 | 0.00 | 0.00 | +0.00 | hold |
| VOYA INVESTMENT MANAGEMENT LLC | 13,146 | 13,146 | 0 | 0.00 | 0.00 | +0.00 | hold |
| PERCEPTIVE ADVISORS LLC | 5,421,568 | 5,421,568 | 0 | 0.25 | 0.20 | -0.05 | hold |
| Commodore Capital LP | 5,397,488 | 5,397,488 | 0 | 0.43 | 0.74 | +0.31 | hold |
| Nuveen, LLC | 78,659 | 78,659 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Police & Firemen's Retirement System of New Jersey | 17,638 | 17,638 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Legal & General Group Plc | 5,504 | 5,504 | 0 | 0.00 | 0.00 | +0.00 | hold |
| PRICE T ROWE ASSOCIATES INC /MD/ | 30,606 | 30,606 | 0 | 0.00 | 0.00 | +0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 47,900 | 47,900 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 152,298 | 152,298 | 0 | 0.00 | 0.00 | +0.00 | hold |
| BLAIR WILLIAM & CO/IL | 152,953 | 152,953 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 3,776 | 3,715 | -61 | 0.00 | 0.00 | +0.00 | sell |
| Arax Advisory Partners | 86 | 0 | -86 | 0.00 | 0.00 | -0.00 | sell |
| AMALGAMATED BANK | 2,065 | 1,900 | -165 | 0.00 | 0.00 | +0.00 | sell |
| Tower Research Capital LLC (TRC) | 7,046 | 6,509 | -537 | 0.00 | 0.00 | +0.00 | sell |
| Sterling Capital Management LLC | 3,827 | 3,220 | -607 | 0.00 | 0.00 | +0.00 | sell |
| Invesco Ltd. | 33,034 | 32,262 | -772 | 0.00 | 0.00 | -0.00 | sell |
| Bank of New York Mellon Corp | 138,667 | 137,485 | -1,182 | 0.00 | 0.00 | +0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 15,640 | 12,891 | -2,749 | 0.00 | 0.00 | -0.00 | sell |
| INTECH INVESTMENT MANAGEMENT LLC | 31,918 | 26,884 | -5,034 | 0.00 | 0.00 | +0.00 | sell |
| RHUMBLINE ADVISERS | 57,551 | 47,163 | -10,388 | 0.00 | 0.00 | +0.00 | sell |
| DEUTSCHE BANK AG\ | 80,496 | 54,909 | -25,587 | 0.00 | 0.00 | -0.00 | sell |
| FMR LLC | 105,770 | 57,374 | -48,396 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 374,336 | 322,720 | -51,616 | 0.00 | 0.00 | +0.00 | sell |