| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 4,997,586 | 6,065,308 | +1,067,722 | 0.17 | 0.21 | +0.05 | buy |
| STATE STREET CORP | 1,346,904 | 2,143,992 | +797,088 | 0.00 | 0.01 | +0.00 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 790,689 | 1,237,830 | +447,141 | 0.01 | 0.02 | +0.01 | buy |
| Soleus Capital Management, L.P. | 148,696 | 573,614 | +424,918 | 0.58 | 1.92 | +1.34 | buy |
| BANK OF AMERICA CORP /DE/ | 390,474 | 713,452 | +322,978 | 0.00 | 0.00 | +0.00 | buy |
| Hood River Capital Management LLC | 0 | 280,028 | +280,028 | 0.00 | 0.24 | +0.24 | buy |
| GOLDMAN SACHS GROUP INC | 450,838 | 724,317 | +273,479 | 0.00 | 0.01 | +0.00 | buy |
| NORGES BANK | 0 | 263,175 | +263,175 | 0.00 | 0.00 | +0.00 | buy |
| PERCEPTIVE ADVISORS LLC | 0 | 259,545 | +259,545 | 0.00 | 0.38 | +0.38 | buy |
| BNP Paribas Asset Management Holding S.A. | 0 | 257,228 | +257,228 | 0.00 | 0.02 | +0.02 | buy |
| Logos Global Management LP | 0 | 225,000 | +225,000 | 0.00 | 1.18 | +1.18 | buy |
| Handelsbanken Fonder AB | 0 | 213,500 | +213,500 | 0.00 | 0.05 | +0.05 | buy |
| Patient Square Capital LP | 104,262 | 298,682 | +194,420 | 2.04 | 5.05 | +3.01 | buy |
| SEGALL BRYANT & HAMILL, LLC | 0 | 185,024 | +185,024 | 0.00 | 0.20 | +0.20 | buy |
| Candriam S.C.A. | 403,026 | 569,590 | +166,564 | 0.15 | 0.22 | +0.07 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1,283,288 | 1,420,375 | +137,087 | 0.01 | 0.01 | +0.00 | buy |
| FEDERATED HERMES, INC. | 346,522 | 481,961 | +135,439 | 0.04 | 0.06 | +0.02 | buy |
| Bank of New York Mellon Corp | 445,527 | 565,579 | +120,052 | 0.01 | 0.01 | +0.00 | buy |
| TimesSquare Capital Management, LLC | 300,649 | 395,827 | +95,178 | 0.32 | 0.47 | +0.16 | buy |
| Palo Alto Investors LP | 64,700 | 156,421 | +91,721 | 0.88 | 1.72 | +0.84 | buy |
| WELLS FARGO & COMPANY/MN | 27,065 | 115,437 | +88,372 | 0.00 | 0.00 | +0.00 | buy |
| Voleon Capital Management LP | 86,529 | 173,067 | +86,538 | 0.15 | 0.29 | +0.14 | buy |
| NAN FUNG TRINITY (HK) Ltd | 156,265 | 227,479 | +71,214 | 1.14 | 1.42 | +0.28 | buy |
| AMERIPRISE FINANCIAL INC | 203,068 | 271,480 | +68,412 | 0.00 | 0.00 | +0.00 | buy |
| Vestal Point Capital, LP | 0 | 66,000 | +66,000 | 0.00 | 0.19 | +0.19 | buy |
| Qube Research & Technologies Ltd | 45,052 | 109,001 | +63,949 | 0.00 | 0.01 | +0.01 | buy |
| MARSHALL WACE, LLP | 39,832 | 102,703 | +62,871 | 0.00 | 0.01 | +0.00 | buy |
| TCG Crossover Management, LLC | 0 | 62,049 | +62,049 | 0.00 | 0.16 | +0.16 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 13,243 | 72,194 | +58,951 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 601,073 | 655,778 | +54,705 | 0.03 | 0.03 | -0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,010,022 | 1,062,926 | +52,904 | 0.00 | 0.01 | +0.00 | buy |
| VANGUARD GROUP INC | 2,545,369 | 2,596,089 | +50,720 | 0.00 | 0.00 | +0.00 | buy |
| Rhenman & Partners Asset Management AB | 56,255 | 106,255 | +50,000 | 0.46 | 0.78 | +0.33 | buy |
| FRANKLIN RESOURCES INC | 601,137 | 650,715 | +49,578 | 0.01 | 0.01 | +0.00 | buy |
| Hillsdale Investment Management Inc. | 0 | 47,630 | +47,630 | 0.00 | 0.10 | +0.10 | buy |
| TWO SIGMA INVESTMENTS, LP | 343,126 | 388,542 | +45,416 | 0.04 | 0.05 | +0.01 | buy |
| UBS Group AG | 275,842 | 320,783 | +44,941 | 0.00 | 0.01 | +0.00 | buy |
| Squarepoint Ops LLC | 127,903 | 172,426 | +44,523 | 0.02 | 0.03 | +0.01 | buy |
| BlackRock, Inc. | 3,602,434 | 3,645,286 | +42,852 | 0.00 | 0.00 | +0.00 | buy |
| THRIVENT FINANCIAL FOR LUTHERANS | 0 | 41,857 | +41,857 | 0.00 | 0.01 | +0.01 | buy |
| XTX Topco Ltd | 0 | 40,249 | +40,249 | 0.00 | 0.08 | +0.08 | buy |
| Rafferty Asset Management, LLC | 33,127 | 72,943 | +39,816 | 0.01 | 0.02 | +0.01 | buy |
| CenterBook Partners LP | 8,357 | 45,367 | +37,010 | 0.03 | 0.18 | +0.14 | buy |
| Pictet Asset Management Holding SA | 541,277 | 577,274 | +35,997 | 0.04 | 0.04 | +0.01 | buy |
| SEI INVESTMENTS CO | 15,604 | 46,078 | +30,474 | 0.00 | 0.00 | +0.00 | buy |
| ZACKS INVESTMENT MANAGEMENT | 0 | 30,398 | +30,398 | 0.00 | 0.02 | +0.02 | buy |
| Faithward Advisors, LLC | 0 | 27,341 | +27,341 | 0.00 | 0.32 | +0.32 | buy |
| BARCLAYS PLC | 115,771 | 142,144 | +26,373 | 0.00 | 0.00 | +0.00 | buy |
| CAPITAL FUND MANAGEMENT S.A. | 36,115 | 62,313 | +26,198 | 0.03 | 0.05 | +0.02 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 495,976 | 521,652 | +25,676 | 0.11 | 0.11 | -0.01 | buy |
| D. E. Shaw & Co., Inc. | 923,509 | 948,161 | +24,652 | 0.05 | 0.06 | +0.00 | buy |
| Allianz Asset Management GmbH | 2,800 | 27,444 | +24,644 | 0.00 | 0.00 | +0.00 | buy |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 313,259 | 336,701 | +23,442 | 0.06 | 0.07 | +0.01 | buy |
| EMERALD MUTUAL FUND ADVISERS TRUST | 219,038 | 242,320 | +23,282 | 0.83 | 0.93 | +0.10 | buy |
| F/m Investments LLC | 29,806 | 53,088 | +23,282 | 0.08 | 0.16 | +0.08 | buy |
| Sofinnova Investments, Inc. | 0 | 23,100 | +23,100 | 0.00 | 0.08 | +0.08 | buy |
| Pathstone Holdings, LLC | 0 | 21,676 | +21,676 | 0.00 | 0.01 | +0.01 | buy |
| PROFUND ADVISORS LLC | 7,576 | 27,091 | +19,515 | 0.02 | 0.07 | +0.05 | buy |
| Creative Planning | 12,744 | 31,519 | +18,775 | 0.00 | 0.00 | +0.00 | buy |
| SG Americas Securities, LLC | 0 | 18,710 | +18,710 | 0.00 | 0.00 | +0.00 | buy |
| MARTINGALE ASSET MANAGEMENT L P | 0 | 18,226 | +18,226 | 0.00 | 0.04 | +0.04 | buy |
| ALPS ADVISORS INC | 24,023 | 42,097 | +18,074 | 0.01 | 0.02 | +0.01 | buy |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 6,574 | 24,126 | +17,552 | 0.00 | 0.00 | +0.00 | buy |
| MACKENZIE FINANCIAL CORP | 3,787 | 19,889 | +16,102 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 394,489 | 409,286 | +14,797 | 0.00 | 0.01 | +0.00 | buy |
| Fisher Asset Management, LLC | 0 | 14,089 | +14,089 | 0.00 | 0.00 | +0.00 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 6,802 | 20,486 | +13,684 | 0.00 | 0.00 | +0.00 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 20,696 | 33,696 | +13,000 | 0.00 | 0.00 | +0.00 | buy |
| Persistent Asset Partners Ltd | 0 | 10,189 | +10,189 | 0.00 | 0.39 | +0.39 | buy |
| NewEdge Advisors, LLC | 0 | 10,000 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| NOMURA HOLDINGS INC | 0 | 9,876 | +9,876 | 0.00 | 0.00 | +0.00 | buy |
| GUGGENHEIM CAPITAL LLC | 0 | 9,772 | +9,772 | 0.00 | 0.01 | +0.01 | buy |
| Legato Capital Management LLC | 34,567 | 44,124 | +9,557 | 0.28 | 0.30 | +0.02 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 22,440 | 31,659 | +9,219 | 0.00 | 0.00 | +0.00 | buy |
| Verition Fund Management LLC | 0 | 8,251 | +8,251 | 0.00 | 0.00 | +0.00 | buy |
| TD ASSET MANAGEMENT INC | 15,400 | 23,276 | +7,876 | 0.00 | 0.00 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 1,942 | 9,274 | +7,332 | 0.00 | 0.00 | +0.00 | buy |
| NEXT CENTURY GROWTH INVESTORS LLC | 360,934 | 368,035 | +7,101 | 1.93 | 2.02 | +0.09 | buy |
| FMR LLC | 640,218 | 646,466 | +6,248 | 0.00 | 0.00 | +0.00 | buy |
| Dana Investment Advisors, Inc. | 0 | 6,105 | +6,105 | 0.00 | 0.01 | +0.01 | buy |
| Freestone Grove Partners LP | 0 | 5,692 | +5,692 | 0.00 | 0.00 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 28,490 | 34,114 | +5,624 | 0.00 | 0.00 | +0.00 | buy |
| NorthCrest Asset Manangement, LLC | 0 | 5,369 | +5,369 | 0.00 | 0.01 | +0.01 | buy |
| LPL Financial LLC | 0 | 5,213 | +5,213 | 0.00 | 0.00 | +0.00 | buy |
| ROYAL BANK OF CANADA | 15,260 | 20,172 | +4,912 | 0.00 | 0.00 | +0.00 | buy |
| State of Wyoming | 0 | 4,687 | +4,687 | 0.00 | 0.04 | +0.04 | buy |
| Steward Partners Investment Advisory, LLC | 1,931 | 6,231 | +4,300 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 0 | 3,872 | +3,872 | 0.00 | 0.00 | +0.00 | buy |
| Y-Intercept (Hong Kong) Ltd | 11,025 | 14,368 | +3,343 | 0.02 | 0.03 | +0.01 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 33,125 | 36,411 | +3,286 | 0.00 | 0.00 | +0.00 | buy |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 3,200 | 6,450 | +3,250 | 0.00 | 0.00 | +0.00 | buy |
| Sumitomo Mitsui Trust Group, Inc. | 0 | 3,038 | +3,038 | 0.00 | 0.00 | +0.00 | buy |
| MQS Management LLC | 0 | 2,902 | +2,902 | 0.00 | 0.14 | +0.14 | buy |
| Man Group plc | 3,960 | 6,841 | +2,881 | 0.00 | 0.00 | +0.00 | buy |
| Graham Capital Management, L.P. | 4,321 | 7,180 | +2,859 | 0.01 | 0.02 | +0.01 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 20,444 | 23,292 | +2,848 | 0.00 | 0.00 | +0.00 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 12,115 | 14,815 | +2,700 | 0.00 | 0.00 | +0.00 | buy |
| Forefront Analytics, LLC | 0 | 2,663 | +2,663 | 0.00 | 0.19 | +0.19 | buy |
| TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY | 14,724 | 17,382 | +2,658 | 0.01 | 0.01 | +0.00 | buy |
| WETZEL INVESTMENT ADVISORS, INC. | 0 | 2,600 | +2,600 | 0.00 | 0.08 | +0.08 | buy |