| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Nantahala Capital Management, LLC | 5,597,433 | 12,326,184 | +6,728,751 | 1.31 | 0.80 | -0.51 | buy |
| Redmile Group, LLC | 15,470,502 | 11,526,710 | -3,943,792 | 3.84 | 0.83 | -3.01 | sell |
| TCG Crossover Management, LLC | 11,390,175 | 11,390,175 | 0 | 1.22 | 0.29 | -0.93 | hold |
| Prosight Management, LP | 8,300,000 | 7,824,749 | -475,251 | 5.10 | 1.44 | -3.66 | sell |
| BlackRock, Inc. | 6,250,747 | 7,020,093 | +769,346 | 0.00 | 0.00 | -0.00 | buy |
| Point72 Asset Management, L.P. | 3,382,129 | 3,649,144 | +267,015 | 0.02 | 0.01 | -0.02 | buy |
| MORGAN STANLEY | 3,812,582 | 3,051,173 | -761,409 | 0.00 | 0.00 | -0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 3,119,154 | 2,899,535 | -219,619 | 0.01 | 0.00 | -0.01 | sell |
| CITADEL ADVISORS LLC | 399,721 | 2,053,316 | +1,653,595 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 1,653,026 | 1,914,424 | +261,398 | 0.00 | 0.00 | -0.00 | buy |
| STATE STREET CORP | 1,566,662 | 1,685,836 | +119,174 | 0.00 | 0.00 | -0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,203,756 | 1,445,546 | +241,790 | 0.00 | 0.00 | -0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 1,325,017 | 1,288,206 | -36,811 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 668,022 | 773,414 | +105,392 | 0.00 | 0.00 | -0.00 | buy |
| Blue Owl Capital Holdings LP | 733,568 | 733,568 | 0 | 0.70 | 0.12 | -0.58 | hold |
| D. E. Shaw & Co., Inc. | 243,176 | 719,320 | +476,144 | 0.00 | 0.00 | -0.00 | buy |
| Opaleye Management Inc. | 0 | 700,000 | +700,000 | 0.00 | 0.07 | +0.07 | buy |
| AQR CAPITAL MANAGEMENT LLC | 237,637 | 658,125 | +420,488 | 0.00 | 0.00 | -0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 860,491 | 652,849 | -207,642 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 552,201 | 594,025 | +41,824 | 0.00 | 0.00 | -0.00 | buy |
| PLATINUM INVESTMENT MANAGEMENT LTD | 990,778 | 581,609 | -409,169 | 0.94 | 0.15 | -0.78 | sell |
| PANAGORA ASSET MANAGEMENT INC | 691,275 | 572,816 | -118,459 | 0.01 | 0.00 | -0.01 | sell |
| UBS Group AG | 458,902 | 520,293 | +61,391 | 0.00 | 0.00 | -0.00 | buy |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 418,782 | 418,782 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ACADIAN ASSET MANAGEMENT LLC | 449,122 | 360,251 | -88,871 | 0.00 | 0.00 | -0.00 | sell |
| WELLS FARGO & COMPANY/MN | 262,783 | 307,144 | +44,361 | 0.00 | 0.00 | -0.00 | buy |
| Russell Investments Group, Ltd. | 254,909 | 265,358 | +10,449 | 0.00 | 0.00 | -0.00 | buy |
| Bank of New York Mellon Corp | 202,254 | 251,645 | +49,391 | 0.00 | 0.00 | -0.00 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 231,064 | 234,355 | +3,291 | 0.00 | 0.00 | -0.00 | buy |
| Florida Trust Wealth Management Co | 150,435 | 230,435 | +80,000 | 0.02 | 0.01 | -0.01 | buy |
| Sixth Street Partners Management Company, L.P. | 0 | 224,058 | +224,058 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 224,361 | 224,058 | -303 | 0.00 | 0.00 | -0.00 | sell |
| Nuveen, LLC | 146,258 | 176,693 | +30,435 | 0.00 | 0.00 | -0.00 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 126,823 | 160,200 | +33,377 | 0.00 | 0.00 | -0.00 | buy |
| JPMORGAN CHASE & CO | 489,079 | 152,540 | -336,539 | 0.00 | 0.00 | -0.00 | sell |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 0 | 141,344 | +141,344 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 17,422 | 140,341 | +122,919 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 172,678 | 132,775 | -39,903 | 0.00 | 0.00 | -0.00 | sell |
| RHUMBLINE ADVISERS | 104,051 | 117,364 | +13,313 | 0.00 | 0.00 | -0.00 | buy |
| Focus Partners Wealth | 0 | 111,801 | +111,801 | 0.00 | 0.00 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 41,850 | 108,470 | +66,620 | 0.00 | 0.00 | +0.00 | buy |
| Quadrature Capital Ltd | 0 | 105,690 | +105,690 | 0.00 | 0.00 | +0.00 | buy |
| Revolve Wealth Partners, LLC | 0 | 100,000 | +100,000 | 0.00 | 0.01 | +0.01 | buy |
| Wilmington Savings Fund Society, FSB | 100,000 | 100,000 | 0 | 0.01 | 0.00 | -0.01 | hold |
| BARCLAYS PLC | 46,335 | 94,264 | +47,929 | 0.00 | 0.00 | -0.00 | buy |
| DEUTSCHE BANK AG\ | 80,205 | 83,444 | +3,239 | 0.00 | 0.00 | -0.00 | buy |
| DAFNA Capital Management LLC | 72,081 | 77,081 | +5,000 | 0.06 | 0.02 | -0.05 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 70,047 | 74,860 | +4,813 | 0.00 | 0.00 | -0.00 | buy |
| Invesco Ltd. | 41,630 | 55,762 | +14,132 | 0.00 | 0.00 | -0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 0 | 54,695 | +54,695 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 31,670 | 49,672 | +18,002 | 0.00 | 0.00 | -0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 47,910 | 49,270 | +1,360 | 0.00 | 0.00 | -0.00 | buy |
| Verition Fund Management LLC | 0 | 40,330 | +40,330 | 0.00 | 0.00 | +0.00 | buy |
| Magnetar Financial LLC | 39,092 | 39,092 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Brevan Howard Capital Management LP | 0 | 36,885 | +36,885 | 0.00 | 0.00 | +0.00 | buy |
| SEI INVESTMENTS CO | 33,461 | 33,461 | 0 | 0.00 | 0.00 | -0.00 | hold |
| DLK Investment Management, LLC | 25,305 | 33,155 | +7,850 | 0.04 | 0.04 | +0.01 | buy |
| Police & Firemen's Retirement System of New Jersey | 32,544 | 32,544 | 0 | 0.00 | 0.00 | -0.00 | hold |
| State of Alaska, Department of Revenue | 0 | 30,000 | +30,000 | 0.00 | 0.00 | +0.00 | buy |
| Susquehanna Portfolio Strategies, LLC | 64,523 | 28,864 | -35,659 | 0.00 | 0.00 | -0.00 | sell |
| INTECH INVESTMENT MANAGEMENT LLC | 23,988 | 28,273 | +4,285 | 0.00 | 0.00 | -0.00 | buy |
| Virtu Financial LLC | 12,098 | 28,174 | +16,076 | 0.00 | 0.00 | -0.00 | buy |
| AXQ CAPITAL, LP | 0 | 27,407 | +27,407 | 0.00 | 0.00 | +0.00 | buy |
| Cerity Partners LLC | 0 | 27,144 | +27,144 | 0.00 | 0.00 | +0.00 | buy |
| Creative Planning | 79,034 | 24,032 | -55,002 | 0.00 | 0.00 | -0.00 | sell |
| Saxony Capital Management, LLC | 23,876 | 23,768 | -108 | 0.05 | 0.01 | -0.04 | sell |
| Neuberger Berman Group LLC | 0 | 20,661 | +20,661 | 0.00 | 0.00 | +0.00 | buy |
| Ground Swell Capital, LLC | 0 | 20,408 | +20,408 | 0.00 | 0.02 | +0.02 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 14,230 | 19,343 | +5,113 | 0.00 | 0.00 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 7,992 | 18,361 | +10,369 | 0.00 | 0.00 | -0.00 | buy |
| Centiva Capital, LP | 0 | 17,683 | +17,683 | 0.00 | 0.00 | +0.00 | buy |
| Vanguard Personalized Indexing Management, LLC | 0 | 17,007 | +17,007 | 0.00 | 0.00 | +0.00 | buy |
| COMMONWEALTH EQUITY SERVICES, LLC | 17,769 | 15,519 | -2,250 | 0.00 | 0.00 | -0.00 | sell |
| PRUDENTIAL FINANCIAL INC | 26,295 | 14,295 | -12,000 | 0.00 | 0.00 | -0.00 | sell |
| ProShare Advisors LLC | 14,799 | 14,044 | -755 | 0.00 | 0.00 | -0.00 | sell |
| R Squared Ltd | 10,119 | 13,926 | +3,807 | 0.02 | 0.01 | -0.01 | buy |
| Engineers Gate Manager LP | 0 | 13,493 | +13,493 | 0.00 | 0.00 | +0.00 | buy |
| Pallas Capital Advisors LLC | 0 | 12,601 | +12,601 | 0.00 | 0.00 | +0.00 | buy |
| Meridian Wealth Management, LLC | 0 | 12,577 | +12,577 | 0.00 | 0.00 | +0.00 | buy |
| Perigon Wealth Management, LLC | 0 | 10,656 | +10,656 | 0.00 | 0.00 | +0.00 | buy |
| AVISO WEALTH MANAGEMENT | 10,343 | 10,343 | 0 | 0.02 | 0.00 | -0.01 | hold |
| Callan Family Office, LLC | 12,873 | 10,086 | -2,787 | 0.00 | 0.00 | -0.00 | sell |
| NEW YORK STATE COMMON RETIREMENT FUND | 9,100 | 9,100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Legal & General Group Plc | 9,012 | 9,012 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SIMPLEX TRADING, LLC | 0 | 8,197 | +8,197 | 0.00 | 0.00 | +0.00 | buy |
| Caitong International Asset Management Co., Ltd | 2 | 7,048 | +7,046 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 6,859 | 6,859 | 0 | 0.00 | 0.00 | -0.00 | hold |
| State of Wyoming | 2,032 | 5,713 | +3,681 | 0.00 | 0.00 | -0.00 | buy |
| JONES FINANCIAL COMPANIES LLLP | 3,000 | 3,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Optiver Holding B.V. | 866 | 2,706 | +1,840 | 0.00 | 0.00 | -0.00 | buy |
| Sterling Capital Management LLC | 663 | 1,802 | +1,139 | 0.00 | 0.00 | -0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 5,573 | 1,431 | -4,142 | 0.00 | 0.00 | -0.00 | sell |
| Arax Advisory Partners | 0 | 1,104 | +1,104 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 966 | 646 | -320 | 0.00 | 0.00 | -0.00 | sell |
| Rockefeller Capital Management L.P. | 1,488 | 431 | -1,057 | 0.00 | 0.00 | -0.00 | sell |
| NISA INVESTMENT ADVISORS, LLC | 370 | 370 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SBI Securities Co., Ltd. | 0 | 222 | +222 | 0.00 | 0.00 | +0.00 | buy |
| IFP Advisors, Inc | 30 | 140 | +110 | 0.00 | 0.00 | +0.00 | buy |
| ROTHSCHILD INVESTMENT LLC | 1 | 121 | +120 | 0.00 | 0.00 | +0.00 | buy |
| Allworth Financial LP | 117 | 104 | -13 | 0.00 | 0.00 | -0.00 | sell |