| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| TFG Asset Management GP Ltd | 145,480 | 203,543 | +58,063 | 0.84 | 1.77 | +0.93 | buy |
| Rock Springs Capital Management LP | 287,967 | 298,218 | +10,251 | 0.51 | 0.80 | +0.30 | buy |
| China Universal Asset Management Co., Ltd. | 7,968 | 9,175 | +1,207 | 0.02 | 0.03 | +0.01 | buy |
| HighVista Strategies LLC | 11,472 | 11,634 | +162 | 0.09 | 0.15 | +0.05 | buy |
| Aaron Wealth Advisors LLC | 1,168,176 | 1,167,799 | -377 | 2.01 | 3.27 | +1.26 | sell |
| Koa Wealth Management, LLC | 17,913 | 17,113 | -800 | 0.39 | 0.64 | +0.26 | sell |
| PFM Health Sciences, LP | 71,894 | 70,971 | -923 | 0.20 | 0.34 | +0.14 | sell |
| TEMA ETFS LLC | 8,877 | 5,010 | -3,867 | 0.02 | 0.01 | -0.01 | sell |
| Candriam S.C.A. | 294,374 | 289,893 | -4,481 | 0.05 | 0.07 | +0.03 | sell |
| EVENTIDE ASSET MANAGEMENT, LLC | 890,000 | 873,492 | -16,508 | 0.44 | 0.64 | +0.20 | sell |
| Goelzer Investment Management, Inc. | 164,172 | 4,000 | -160,172 | 0.24 | 0.01 | -0.23 | sell |
| DAFNA Capital Management LLC | 175,465 | 11,809 | -163,656 | 1.19 | 0.12 | -1.07 | sell |
| EcoR1 Capital, LLC | 777,000 | 388,500 | -388,500 | 0.98 | 1.04 | +0.06 | sell |
| Cormorant Asset Management, LP | 1,120,000 | 550,000 | -570,000 | 1.68 | 1.56 | -0.12 | sell |