| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| FMR LLC | 7,283,411 | 8,159,011 | +875,600 | 0.04 | 0.05 | +0.01 | buy |
| BAILLIE GIFFORD & CO | 8,159,682 | 8,038,872 | -120,810 | 0.65 | 0.64 | -0.01 | sell |
| FLOSSBACH VON STORCH SE | 4,259,631 | 4,230,098 | -29,533 | 1.68 | 1.84 | +0.16 | sell |
| PRIMECAP MANAGEMENT CO/CA/ | 4,046,425 | 4,001,466 | -44,959 | 0.30 | 0.34 | +0.03 | sell |
| PFIZER INC | 3,658,361 | 3,658,361 | 0 | 66.51 | 67.60 | +1.09 | hold |
| T. Rowe Price Investment Management, Inc. | 86,154 | 3,598,472 | +3,512,318 | 0.01 | 0.24 | +0.24 | buy |
| Temasek Holdings (Private) Ltd | 1,807,232 | 1,506,027 | -301,205 | 0.66 | 0.62 | -0.04 | sell |
| BlackRock, Inc. | 1,665,939 | 1,314,027 | -351,912 | 0.00 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 1,195,470 | 1,275,475 | +80,005 | 0.08 | 0.11 | +0.02 | buy |
| Capital International Investors | 1,428,441 | 1,133,473 | -294,968 | 0.03 | 0.02 | -0.00 | sell |
| Bank of New York Mellon Corp | 698,368 | 1,108,719 | +410,351 | 0.01 | 0.02 | +0.01 | buy |
| DODGE & COX | 0 | 877,437 | +877,437 | 0.00 | 0.05 | +0.05 | buy |
| FRANKLIN RESOURCES INC | 425,442 | 751,998 | +326,556 | 0.01 | 0.02 | +0.01 | buy |
| Aberdeen Group plc | 385,668 | 721,928 | +336,260 | 0.07 | 0.13 | +0.06 | buy |
| Invesco Ltd. | 645,142 | 681,100 | +35,958 | 0.01 | 0.01 | +0.00 | buy |
| GILDER GAGNON HOWE & CO LLC | 649,284 | 667,635 | +18,351 | 0.77 | 0.75 | -0.02 | buy |
| Candriam S.C.A. | 670,955 | 586,736 | -84,219 | 0.38 | 0.36 | -0.02 | sell |
| MORGAN STANLEY | 713,606 | 574,692 | -138,914 | 0.00 | 0.00 | -0.00 | sell |
| ALTRINSIC GLOBAL ADVISORS LLC | 620,766 | 496,771 | -123,995 | 2.79 | 1.91 | -0.88 | sell |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 478,257 | 492,045 | +13,788 | 0.05 | 0.05 | +0.00 | buy |
| DekaBank Deutsche Girozentrale | 411,897 | 481,397 | +69,500 | 0.07 | 0.09 | +0.02 | buy |
| Capital International, Inc./CA/ | 638,099 | 470,017 | -168,082 | 0.70 | 0.49 | -0.22 | sell |
| BAKER BROS. ADVISORS LP | 45,031 | 368,923 | +323,892 | 0.05 | 0.38 | +0.34 | buy |
| DEUTSCHE BANK AG\ | 289,788 | 345,566 | +55,778 | 0.01 | 0.01 | +0.00 | buy |
| Squarepoint Ops LLC | 347,727 | 335,660 | -12,067 | 0.08 | 0.08 | +0.00 | sell |
| FIRST TRUST ADVISORS LP | 316,935 | 331,360 | +14,425 | 0.03 | 0.03 | +0.00 | buy |
| Legal & General Group Plc | 253,460 | 315,748 | +62,288 | 0.01 | 0.01 | +0.00 | buy |
| LBP AM SA | 305,221 | 305,470 | +249 | 0.43 | 0.46 | +0.03 | buy |
| TANG CAPITAL MANAGEMENT LLC | 270,000 | 270,000 | 0 | 1.36 | 1.45 | +0.09 | hold |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 243,468 | 262,993 | +19,525 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 493,931 | 258,288 | -235,643 | 0.01 | 0.01 | -0.00 | sell |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 218,422 | 256,874 | +38,452 | 0.01 | 0.01 | +0.00 | buy |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 382,979 | 237,732 | -145,247 | 0.13 | 0.09 | -0.04 | sell |
| GROUPAMA ASSET MANAGMENT | 196,544 | 223,225 | +26,681 | 0.37 | 0.39 | +0.02 | buy |
| CenterBook Partners LP | 109,417 | 215,944 | +106,527 | 0.63 | 1.28 | +0.64 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 0 | 209,985 | +209,985 | 0.00 | 0.01 | +0.01 | buy |
| Long Focus Capital Management, LLC | 159,000 | 207,903 | +48,903 | 0.98 | 1.43 | +0.45 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 177,839 | 192,789 | +14,950 | 0.02 | 0.02 | +0.00 | buy |
| MACQUARIE GROUP LTD | 190,252 | 191,548 | +1,296 | 0.02 | 0.02 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 270,211 | 184,112 | -86,099 | 0.00 | 0.00 | -0.00 | sell |
| Carmignac Gestion | 185,877 | 176,351 | -9,526 | 0.28 | 0.29 | +0.01 | sell |
| TD ASSET MANAGEMENT INC | 11,452 | 173,795 | +162,343 | 0.00 | 0.02 | +0.01 | buy |
| CITIGROUP INC | 261,984 | 164,830 | -97,154 | 0.02 | 0.01 | -0.01 | sell |
| Mitsubishi UFJ Trust & Banking Corp | 178,997 | 161,400 | -17,597 | 0.04 | 0.04 | -0.00 | sell |
| Baader Bank Aktiengesellschaft | 142,822 | 151,862 | +9,040 | 1.31 | 1.38 | +0.07 | buy |
| Amundi | 268,337 | 151,743 | -116,594 | 0.01 | 0.01 | -0.00 | sell |
| Hudson Bay Capital Management LP | 165,000 | 150,000 | -15,000 | 0.10 | 0.10 | +0.01 | sell |
| STATE STREET CORP | 152,911 | 145,309 | -7,602 | 0.00 | 0.00 | +0.00 | sell |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 145,687 | 131,522 | -14,165 | 0.22 | 0.38 | +0.15 | sell |
| BANK OF AMERICA CORP /DE/ | 293,776 | 129,024 | -164,752 | 0.00 | 0.00 | -0.00 | sell |
| Allianz Asset Management GmbH | 120,680 | 123,495 | +2,815 | 0.02 | 0.02 | +0.00 | buy |
| VAN ECK ASSOCIATES CORP | 120,660 | 119,987 | -673 | 0.01 | 0.01 | +0.00 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 101,348 | 103,750 | +2,402 | 0.00 | 0.00 | +0.00 | buy |
| BIT Capital GmbH | 10,586 | 96,089 | +85,503 | 0.12 | 0.67 | +0.55 | buy |
| Woodline Partners LP | 117,498 | 95,498 | -22,000 | 0.07 | 0.05 | -0.02 | sell |
| Susquehanna Portfolio Strategies, LLC | 6,047 | 92,636 | +86,589 | 0.24 | 0.22 | -0.02 | buy |
| EDMOND DE ROTHSCHILD HOLDING S.A. | 82,310 | 92,310 | +10,000 | 0.13 | 0.16 | +0.02 | buy |
| SG Americas Securities, LLC | 38,637 | 90,429 | +51,792 | 0.01 | 0.04 | +0.03 | buy |
| Beacon Pointe Advisors, LLC | 89,516 | 88,041 | -1,475 | 0.09 | 0.10 | +0.01 | sell |
| GROUP ONE TRADING LLC | 63,304 | 73,577 | +10,273 | 0.24 | 0.26 | +0.02 | buy |
| Krensavage Asset Management, LLC | 87,563 | 73,382 | -14,181 | 4.41 | 4.14 | -0.27 | sell |
| AMERICAN CENTURY COMPANIES INC | 74,042 | 66,833 | -7,209 | 0.00 | 0.00 | -0.00 | sell |
| JPMORGAN CHASE & CO | 1,772 | 64,774 | +63,002 | 0.00 | 0.00 | +0.00 | buy |
| Bank Julius Baer & Co. Ltd, Zurich | 61,230 | 64,712 | +3,482 | 0.02 | 0.02 | +0.00 | buy |
| Vontobel Holding Ltd. | 21,882 | 59,972 | +38,090 | 0.01 | 0.02 | +0.01 | buy |
| Pictet Asset Management Holding SA | 48,916 | 59,774 | +10,858 | 0.01 | 0.01 | +0.00 | buy |
| APG Asset Management N.V. | 49,600 | 53,100 | +3,500 | 0.01 | 0.01 | +0.00 | buy |
| Erste Asset Management GmbH | 42,000 | 47,700 | +5,700 | 0.05 | 0.04 | -0.01 | buy |
| Slow Capital, Inc. | 48,761 | 45,346 | -3,415 | 0.59 | 0.59 | -0.00 | sell |
| COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS | 41,706 | 41,706 | 0 | 0.02 | 0.02 | +0.00 | hold |
| SHELL ASSET MANAGEMENT CO | 35,212 | 40,610 | +5,398 | 0.15 | 0.15 | -0.00 | buy |
| Swedbank AB | 37,500 | 39,900 | +2,400 | 0.00 | 0.00 | +0.00 | buy |
| SECTOR GAMMA AS | 30,000 | 37,470 | +7,470 | 0.88 | 1.30 | +0.43 | buy |
| Rhenman & Partners Asset Management AB | 35,750 | 35,870 | +120 | 0.37 | 0.48 | +0.11 | buy |
| Bellevue Group AG | 7,964 | 35,039 | +27,075 | 0.02 | 0.08 | +0.07 | buy |
| Crocodile Capital Partners GmbH | 29,586 | 29,586 | 0 | 3.81 | 5.29 | +1.48 | hold |
| TB Alternative Assets Ltd. | 38,996 | 28,917 | -10,079 | 0.82 | 0.57 | -0.25 | sell |
| AMERIPRISE FINANCIAL INC | 28,526 | 28,815 | +289 | 0.00 | 0.00 | +0.00 | buy |
| USS Investment Management Ltd | 27,822 | 27,822 | 0 | 0.02 | 0.02 | -0.00 | hold |
| Aquatic Capital Management LLC | 20,720 | 26,640 | +5,920 | 0.05 | 0.06 | +0.01 | buy |
| Palo Alto Investors LP | 25,206 | 25,206 | 0 | 0.44 | 0.57 | +0.13 | hold |
| BARCLAYS PLC | 118,934 | 25,094 | -93,840 | 0.00 | 0.00 | -0.00 | sell |
| SCOTIA CAPITAL INC. | 110,081 | 25,081 | -85,000 | 0.05 | 0.01 | -0.04 | sell |
| Quinn Opportunity Partners LLC | 197,946 | 25,075 | -172,871 | 1.27 | 0.23 | -1.04 | sell |
| VOYA INVESTMENT MANAGEMENT LLC | 27,870 | 24,235 | -3,635 | 0.00 | 0.00 | -0.00 | sell |
| Twin Tree Management, LP | 98,640 | 22,077 | -76,563 | 0.20 | 0.06 | -0.14 | sell |
| Robeco Institutional Asset Management B.V. | 77,535 | 20,619 | -56,916 | 0.01 | 0.00 | -0.01 | sell |
| China Universal Asset Management Co., Ltd. | 20,036 | 20,065 | +29 | 0.17 | 0.20 | +0.03 | buy |
| LPL Financial LLC | 11,412 | 19,674 | +8,262 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 28,405 | 18,244 | -10,161 | 0.01 | 0.00 | -0.00 | sell |
| DYMON ASIA CAPITAL (SINGAPORE) PTE. LTD. | 0 | 17,500 | +17,500 | 0.00 | 1.32 | +1.32 | buy |
| Aristides Capital LLC | 14,533 | 17,359 | +2,826 | 0.49 | 0.59 | +0.10 | buy |
| KENNEDY CAPITAL MANAGEMENT LLC | 16,295 | 16,422 | +127 | 0.04 | 0.04 | +0.01 | buy |
| SECTORAL ASSET MANAGEMENT INC | 17,175 | 16,160 | -1,015 | 1.22 | 1.14 | -0.08 | sell |
| Employees Retirement System of Texas | 30,388 | 15,826 | -14,562 | 0.03 | 0.01 | -0.01 | sell |
| HighTower Advisors, LLC | 16,077 | 15,652 | -425 | 0.00 | 0.00 | +0.00 | sell |
| LMR Partners LLP | 2,774 | 15,500 | +12,726 | 0.01 | 0.03 | +0.02 | buy |
| PLATINUM INVESTMENT MANAGEMENT LTD | 0 | 14,863 | +14,863 | 0.00 | 0.11 | +0.11 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 10,650 | 14,130 | +3,480 | 0.00 | 0.00 | +0.00 | buy |
| FRED ALGER MANAGEMENT, LLC | 61,930 | 13,839 | -48,091 | 0.03 | 0.01 | -0.03 | sell |