| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BAILLIE GIFFORD & CO | 8,038,872 | 7,879,359 | -159,513 | 0.64 | 0.58 | -0.06 | sell |
| FMR LLC | 8,159,011 | 5,453,480 | -2,705,531 | 0.05 | 0.03 | -0.02 | sell |
| T. Rowe Price Investment Management, Inc. | 3,598,472 | 4,833,642 | +1,235,170 | 0.24 | 0.29 | +0.05 | buy |
| FLOSSBACH VON STORCH SE | 4,230,098 | 4,230,033 | -65 | 1.84 | 1.64 | -0.20 | sell |
| PRIMECAP MANAGEMENT CO/CA/ | 4,001,466 | 3,870,766 | -130,700 | 0.34 | 0.29 | -0.05 | sell |
| DODGE & COX | 877,437 | 3,647,091 | +2,769,654 | 0.05 | 0.19 | +0.14 | buy |
| PFIZER INC | 3,658,361 | 1,658,361 | -2,000,000 | 67.60 | 37.39 | -30.21 | sell |
| Temasek Holdings (Private) Ltd | 1,506,027 | 1,506,027 | 0 | 0.62 | 0.52 | -0.10 | hold |
| Capital International Investors | 1,133,473 | 1,135,066 | +1,593 | 0.02 | 0.02 | -0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 1,275,475 | 1,103,298 | -172,177 | 0.11 | 0.08 | -0.02 | sell |
| BlackRock, Inc. | 1,314,027 | 765,309 | -548,718 | 0.00 | 0.00 | -0.00 | sell |
| FRANKLIN RESOURCES INC | 751,998 | 732,816 | -19,182 | 0.02 | 0.02 | -0.00 | sell |
| UBS Group AG | 258,288 | 607,440 | +349,152 | 0.01 | 0.01 | +0.01 | buy |
| MORGAN STANLEY | 574,692 | 603,016 | +28,324 | 0.00 | 0.00 | -0.00 | buy |
| Candriam S.C.A. | 586,736 | 589,452 | +2,716 | 0.36 | 0.30 | -0.06 | buy |
| BANK OF AMERICA CORP /DE/ | 129,024 | 573,356 | +444,332 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 1,108,719 | 568,707 | -540,012 | 0.02 | 0.01 | -0.01 | sell |
| DekaBank Deutsche Girozentrale | 481,397 | 481,397 | 0 | 0.09 | 0.08 | -0.01 | hold |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 492,045 | 459,673 | -32,372 | 0.05 | 0.04 | -0.01 | sell |
| VICTORY CAPITAL MANAGEMENT INC | 209,985 | 413,685 | +203,700 | 0.01 | 0.02 | +0.01 | buy |
| Long Focus Capital Management, LLC | 207,903 | 397,655 | +189,752 | 1.43 | 2.24 | +0.81 | buy |
| CITADEL ADVISORS LLC | 2,712 | 389,495 | +386,783 | 0.00 | 0.03 | +0.03 | buy |
| DEUTSCHE BANK AG\ | 345,566 | 382,476 | +36,910 | 0.01 | 0.01 | -0.00 | buy |
| BAKER BROS. ADVISORS LP | 368,923 | 368,923 | 0 | 0.38 | 0.26 | -0.12 | hold |
| LBP AM SA | 305,470 | 353,329 | +47,859 | 0.46 | 0.43 | -0.03 | buy |
| Legal & General Group Plc | 315,748 | 311,583 | -4,165 | 0.01 | 0.01 | -0.00 | sell |
| FIRST TRUST ADVISORS LP | 331,360 | 305,622 | -25,738 | 0.03 | 0.02 | -0.01 | sell |
| Capital International, Inc./CA/ | 470,017 | 293,208 | -176,809 | 0.49 | 0.23 | -0.25 | sell |
| Aberdeen Group plc | 721,928 | 291,907 | -430,021 | 0.13 | 0.05 | -0.09 | sell |
| TANG CAPITAL MANAGEMENT LLC | 270,000 | 270,000 | 0 | 1.45 | 1.02 | -0.43 | hold |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 262,993 | 263,253 | +260 | 0.00 | 0.00 | -0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 0 | 246,327 | +246,327 | 0.00 | 0.02 | +0.02 | buy |
| MACQUARIE GROUP LTD | 191,548 | 231,461 | +39,913 | 0.02 | 0.03 | +0.00 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 192,789 | 210,777 | +17,988 | 0.02 | 0.01 | -0.00 | buy |
| Hudson Bay Capital Management LP | 150,000 | 205,004 | +55,004 | 0.10 | 0.12 | +0.02 | buy |
| JANE STREET GROUP, LLC | 0 | 197,018 | +197,018 | 0.00 | 0.02 | +0.02 | buy |
| GROUPAMA ASSET MANAGMENT | 223,225 | 193,402 | -29,823 | 0.39 | 0.28 | -0.11 | sell |
| CenterBook Partners LP | 215,944 | 185,491 | -30,453 | 1.28 | 0.90 | -0.37 | sell |
| CITIGROUP INC | 164,830 | 179,633 | +14,803 | 0.01 | 0.01 | +0.00 | buy |
| GILDER GAGNON HOWE & CO LLC | 667,635 | 168,871 | -498,764 | 0.75 | 0.17 | -0.58 | sell |
| TD ASSET MANAGEMENT INC | 173,795 | 168,041 | -5,754 | 0.02 | 0.01 | -0.00 | sell |
| Mitsubishi UFJ Trust & Banking Corp | 161,400 | 154,186 | -7,214 | 0.04 | 0.03 | -0.01 | sell |
| Baader Bank Aktiengesellschaft | 151,862 | 152,870 | +1,008 | 1.38 | 1.24 | -0.14 | buy |
| GOLDMAN SACHS GROUP INC | 184,112 | 146,584 | -37,528 | 0.00 | 0.00 | -0.00 | sell |
| STATE STREET CORP | 145,309 | 126,635 | -18,674 | 0.00 | 0.00 | -0.00 | sell |
| Ghisallo Capital Management LLC | 0 | 125,000 | +125,000 | 0.00 | 0.40 | +0.40 | buy |
| Allianz Asset Management GmbH | 123,495 | 120,966 | -2,529 | 0.02 | 0.01 | -0.00 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 103,750 | 115,990 | +12,240 | 0.00 | 0.00 | -0.00 | buy |
| VAN ECK ASSOCIATES CORP | 119,987 | 112,460 | -7,527 | 0.01 | 0.01 | -0.00 | sell |
| Carmignac Gestion | 176,351 | 106,549 | -69,802 | 0.29 | 0.16 | -0.13 | sell |
| Susquehanna Portfolio Strategies, LLC | 92,636 | 92,636 | 0 | 0.22 | 0.14 | -0.07 | hold |
| EDMOND DE ROTHSCHILD HOLDING S.A. | 92,310 | 92,310 | 0 | 0.16 | 0.14 | -0.02 | hold |
| Beacon Pointe Advisors, LLC | 88,041 | 91,380 | +3,339 | 0.10 | 0.08 | -0.02 | buy |
| Amundi | 151,743 | 85,231 | -66,512 | 0.01 | 0.00 | -0.00 | sell |
| Krensavage Asset Management, LLC | 73,382 | 79,366 | +5,984 | 4.14 | 3.33 | -0.80 | buy |
| Squarepoint Ops LLC | 335,660 | 75,904 | -259,756 | 0.08 | 0.02 | -0.06 | sell |
| Invesco Ltd. | 681,100 | 74,156 | -606,944 | 0.01 | 0.00 | -0.01 | sell |
| Vontobel Holding Ltd. | 59,972 | 72,096 | +12,124 | 0.02 | 0.02 | +0.00 | buy |
| Jump Financial, LLC | 9,559 | 70,909 | +61,350 | 0.01 | 0.11 | +0.09 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 14,130 | 65,660 | +51,530 | 0.00 | 0.01 | +0.01 | buy |
| Pictet Asset Management Holding SA | 59,774 | 62,719 | +2,945 | 0.01 | 0.01 | -0.00 | buy |
| Bank Julius Baer & Co. Ltd, Zurich | 64,712 | 62,022 | -2,690 | 0.02 | 0.02 | -0.00 | sell |
| JPMORGAN CHASE & CO | 64,774 | 60,156 | -4,618 | 0.00 | 0.00 | -0.00 | sell |
| Alyeska Investment Group, L.P. | 0 | 57,668 | +57,668 | 0.00 | 0.02 | +0.02 | buy |
| GROUP ONE TRADING LLC | 73,577 | 57,030 | -16,547 | 0.26 | 0.17 | -0.09 | sell |
| APG Asset Management N.V. | 53,100 | 54,700 | +1,600 | 0.01 | 0.01 | -0.00 | buy |
| Swedbank AB | 39,900 | 49,900 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| Woodline Partners LP | 95,498 | 48,498 | -47,000 | 0.05 | 0.02 | -0.03 | sell |
| AMERICAN CENTURY COMPANIES INC | 66,833 | 48,027 | -18,806 | 0.00 | 0.00 | -0.00 | sell |
| Erste Asset Management GmbH | 47,700 | 47,700 | 0 | 0.04 | 0.05 | +0.00 | hold |
| Slow Capital, Inc. | 45,346 | 42,022 | -3,324 | 0.59 | 0.49 | -0.10 | sell |
| COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS | 41,706 | 41,706 | 0 | 0.02 | 0.02 | -0.00 | hold |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 131,522 | 41,387 | -90,135 | 0.38 | 0.16 | -0.22 | sell |
| HRT FINANCIAL LP | 0 | 36,921 | +36,921 | 0.00 | 0.01 | +0.01 | buy |
| Rhenman & Partners Asset Management AB | 35,870 | 35,870 | 0 | 0.48 | 0.39 | -0.09 | hold |
| Bellevue Group AG | 35,039 | 33,955 | -1,084 | 0.08 | 0.07 | -0.01 | sell |
| SCOTIA CAPITAL INC. | 25,081 | 31,600 | +6,519 | 0.01 | 0.01 | +0.00 | buy |
| Crocodile Capital Partners GmbH | 29,586 | 29,586 | 0 | 5.29 | 2.38 | -2.92 | hold |
| AMERIPRISE FINANCIAL INC | 28,815 | 28,794 | -21 | 0.00 | 0.00 | -0.00 | sell |
| USS Investment Management Ltd | 27,822 | 27,822 | 0 | 0.02 | 0.01 | -0.01 | hold |
| SECTOR GAMMA AS | 37,470 | 27,732 | -9,738 | 1.30 | 0.68 | -0.63 | sell |
| Aristides Capital LLC | 17,359 | 25,359 | +8,000 | 0.59 | 0.74 | +0.15 | buy |
| Quinn Opportunity Partners LLC | 25,075 | 23,000 | -2,075 | 0.23 | 0.17 | -0.06 | sell |
| Quadrature Capital Ltd | 0 | 22,203 | +22,203 | 0.00 | 0.03 | +0.03 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 24,235 | 21,360 | -2,875 | 0.00 | 0.00 | -0.00 | sell |
| KENNEDY CAPITAL MANAGEMENT LLC | 16,422 | 20,931 | +4,509 | 0.04 | 0.05 | +0.00 | buy |
| SG Americas Securities, LLC | 90,429 | 20,703 | -69,726 | 0.04 | 0.01 | -0.03 | sell |
| SIMPLEX TRADING, LLC | 7,606 | 20,361 | +12,755 | 0.02 | 0.04 | +0.02 | buy |
| Palo Alto Investors LP | 25,206 | 19,614 | -5,592 | 0.57 | 0.36 | -0.21 | sell |
| BANQUE PICTET & CIE SA | 5,114 | 19,311 | +14,197 | 0.01 | 0.02 | +0.01 | buy |
| Privium Fund Management B.V. | 10,987 | 19,000 | +8,013 | 0.25 | 0.34 | +0.08 | buy |
| LMR Partners LLP | 15,500 | 18,538 | +3,038 | 0.03 | 0.02 | -0.00 | buy |
| LPL Financial LLC | 19,674 | 18,357 | -1,317 | 0.00 | 0.00 | -0.00 | sell |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 18,244 | 17,746 | -498 | 0.00 | 0.00 | -0.00 | sell |
| SECTORAL ASSET MANAGEMENT INC | 16,160 | 17,660 | +1,500 | 1.14 | 1.07 | -0.06 | buy |
| China Universal Asset Management Co., Ltd. | 20,065 | 17,634 | -2,431 | 0.20 | 0.14 | -0.06 | sell |
| IMC-Chicago, LLC | 0 | 17,406 | +17,406 | 0.00 | 0.03 | +0.03 | buy |
| Limestone Investment Advisors LP | 17,190 | 17,190 | 0 | 0.79 | 0.76 | -0.03 | hold |
| PLATINUM INVESTMENT MANAGEMENT LTD | 14,863 | 16,902 | +2,039 | 0.11 | 0.11 | +0.00 | buy |
| NOMURA HOLDINGS INC | 7,683 | 16,665 | +8,982 | 0.01 | 0.01 | +0.00 | buy |