| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Caligan Partners LP | 0 | 756,538 | +756,538 | 0.00 | 0.37 | +0.37 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 0 | 378,269 | +378,269 | 0.00 | 0.02 | +0.02 | buy |
| Exome Asset Management LLC | 0 | 325,762 | +325,762 | 0.00 | 0.52 | +0.52 | buy |
| MARSHALL WACE, LLP | 0 | 71,088 | +71,088 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 19,763 | 85,144 | +65,381 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 558,700 | 617,100 | +58,400 | 0.00 | 0.00 | +0.00 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 33,550 | 81,262 | +47,712 | 0.01 | 0.01 | +0.00 | buy |
| Atom Investors LP | 0 | 29,612 | +29,612 | 0.00 | 0.01 | +0.01 | buy |
| Man Group plc | 110,624 | 134,977 | +24,353 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 36,123 | 60,407 | +24,284 | 0.00 | 0.00 | +0.00 | buy |
| Mariner, LLC | 13,598 | 31,535 | +17,937 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 101,699 | 110,373 | +8,674 | 0.00 | 0.00 | -0.00 | buy |
| Qube Research & Technologies Ltd | 2,168 | 4,065 | +1,897 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 574,901 | 575,580 | +679 | 0.00 | 0.00 | -0.00 | buy |
| SIMPLEX TRADING, LLC | 4 | 84 | +80 | 0.00 | 0.00 | 0.00 | buy |
| Frazier Financial Advisors, LLC | 300 | 375 | +75 | 0.00 | 0.00 | +0.00 | buy |
| Temasek Holdings (Private) Ltd | 566,650 | 566,650 | 0 | 0.01 | 0.01 | -0.00 | hold |
| RENAISSANCE TECHNOLOGIES LLC | 63,800 | 63,800 | 0 | 0.00 | 0.00 | -0.00 | hold |
| RHUMBLINE ADVISERS | 1,371 | 1,371 | 0 | 0.00 | 0.00 | -0.00 | hold |
| GEODE CAPITAL MANAGEMENT, LLC | 34,347 | 34,347 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Alberta Investment Management Corp | 74,723 | 74,723 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Donald L. Hagan, LLC | 30,000 | 30,000 | 0 | 0.03 | 0.03 | -0.00 | hold |
| Aberdeen Group plc | 162,580 | 162,580 | 0 | 0.00 | 0.00 | -0.00 | hold |
| HHLR ADVISORS, LTD. | 6,909,220 | 6,909,220 | 0 | 0.26 | 0.28 | +0.01 | hold |
| GAMMA Investing LLC | 63 | 63 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Legal & General Group Plc | 1,191 | 1,191 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CITIGROUP INC | 50 | 50 | 0 | 0.00 | 0.00 | -0.00 | hold |
| XTX Topco Ltd | 35,951 | 30,485 | -5,466 | 0.01 | 0.01 | -0.01 | sell |
| Headlands Technologies LLC | 7,698 | 0 | -7,698 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA SECURITIES, LLC | 11,073 | 0 | -11,073 | 0.00 | 0.00 | -0.00 | sell |
| HRT FINANCIAL LP | 17,354 | 0 | -17,354 | 0.00 | 0.00 | -0.00 | sell |
| NOMURA HOLDINGS INC | 23,000 | 0 | -23,000 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 24,608 | 0 | -24,608 | 0.00 | 0.00 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 145,195 | 84,941 | -60,254 | 0.00 | 0.00 | -0.00 | sell |
| CITADEL ADVISORS LLC | 74,029 | 0 | -74,029 | 0.00 | 0.00 | -0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 191,301 | 93,508 | -97,793 | 0.00 | 0.00 | -0.00 | sell |
| Diametric Capital, LP | 99,295 | 0 | -99,295 | 0.11 | 0.00 | -0.11 | sell |
| GSA CAPITAL PARTNERS LLP | 538,119 | 432,621 | -105,498 | 0.09 | 0.06 | -0.02 | sell |
| BARCLAYS PLC | 173,064 | 38,552 | -134,512 | 0.00 | 0.00 | -0.00 | sell |
| ACADIAN ASSET MANAGEMENT LLC | 155,572 | 0 | -155,572 | 0.00 | 0.00 | -0.00 | sell |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 310,499 | 0 | -310,499 | 0.00 | 0.00 | -0.00 | sell |
| CANADA PENSION PLAN INVESTMENT BOARD | 313,600 | 0 | -313,600 | 0.00 | 0.00 | -0.00 | sell |
| MORGAN STANLEY | 516,696 | 0 | -516,696 | 0.00 | 0.00 | -0.00 | sell |