| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| VANGUARD GROUP INC | 333,865 | 586,440 | +252,575 | 0.00 | 0.00 | -0.00 | buy |
| NORTHERN TRUST CORP | 98,012 | 315,365 | +217,353 | 0.00 | 0.00 | +0.00 | buy |
| Almitas Capital LLC | 192,007 | 234,378 | +42,371 | 0.12 | 0.12 | -0.00 | buy |
| CITADEL ADVISORS LLC | 790,639 | 830,936 | +40,297 | 0.00 | 0.00 | -0.00 | buy |
| XTX Topco Ltd | 0 | 25,917 | +25,917 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 0 | 15,360 | +15,360 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 14,400 | +14,400 | 0.00 | 0.00 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 0 | 11,809 | +11,809 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 235,859 | 247,143 | +11,284 | 0.00 | 0.00 | -0.00 | buy |
| RHUMBLINE ADVISERS | 7,811 | 12,231 | +4,420 | 0.00 | 0.00 | -0.00 | buy |
| STATE STREET CORP | 44,077 | 48,186 | +4,109 | 0.00 | 0.00 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 4,095 | 6,418 | +2,323 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 8,993 | 9,398 | +405 | 0.00 | 0.00 | -0.00 | buy |
| CWM, LLC | 96 | 430 | +334 | 0.00 | 0.00 | +0.00 | buy |
| Sterling Capital Management LLC | 12 | 119 | +107 | 0.00 | 0.00 | +0.00 | buy |
| True Wealth Design, LLC | 0 | 5 | +5 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 0 | 3 | +3 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 618 | 618 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 1,309 | 1,309 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SECTORAL ASSET MANAGEMENT INC | 678,574 | 678,574 | 0 | 1.31 | 0.80 | -0.52 | hold |
| RA CAPITAL MANAGEMENT, L.P. | 2,180,631 | 2,180,631 | 0 | 0.08 | 0.05 | -0.03 | hold |
| PRELUDE CAPITAL MANAGEMENT, LLC | 16,624 | 16,624 | 0 | 0.00 | 0.00 | -0.00 | hold |
| O'SHAUGHNESSY ASSET MANAGEMENT, LLC | 12,272 | 12,272 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PFM Health Sciences, LP | 240,513 | 240,513 | 0 | 0.05 | 0.03 | -0.03 | hold |
| Alyeska Investment Group, L.P. | 300,000 | 300,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Ensign Peak Advisors, Inc | 187,500 | 187,500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Sio Capital Management, LLC | 162,058 | 162,058 | 0 | 0.13 | 0.07 | -0.06 | hold |
| Walleye Capital LLC | 39,624 | 39,624 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Boxer Capital Management, LLC | 250,000 | 250,000 | 0 | 0.06 | 0.11 | +0.05 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| Legal & General Group Plc | 1,449 | 1,449 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 22,100 | 22,100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 40,458 | 40,458 | 0 | 0.00 | 0.00 | -0.00 | hold |
| WELLINGTON MANAGEMENT GROUP LLP | 556,233 | 556,233 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ACADIAN ASSET MANAGEMENT LLC | 22,087 | 22,087 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AMALGAMATED BANK | 218 | 218 | 0 | 0.00 | 0.00 | -0.00 | hold |
| DEUTSCHE BANK AG\ | 97 | 0 | -97 | 0.00 | 0.00 | -0.00 | sell |
| Avior Wealth Management, LLC | 122 | 0 | -122 | 0.00 | 0.00 | -0.00 | sell |
| Corebridge Financial, Inc. | 8,379 | 8,257 | -122 | 0.00 | 0.00 | -0.00 | sell |
| NISA INVESTMENT ADVISORS, LLC | 388 | 208 | -180 | 0.00 | 0.00 | -0.00 | sell |
| Russell Investments Group, Ltd. | 556 | 265 | -291 | 0.00 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 19,778 | 18,893 | -885 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 13,306 | 11,870 | -1,436 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 26,169 | 17,855 | -8,314 | 0.00 | 0.00 | -0.00 | sell |
| SG Americas Securities, LLC | 10,753 | 0 | -10,753 | 0.00 | 0.00 | -0.00 | sell |
| Verition Fund Management LLC | 11,665 | 0 | -11,665 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 13,808 | 0 | -13,808 | 0.00 | 0.00 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 48,672 | 34,427 | -14,245 | 0.00 | 0.00 | -0.00 | sell |
| Redmile Group, LLC | 740,204 | 725,204 | -15,000 | 0.15 | 0.10 | -0.05 | sell |
| BlackRock, Inc. | 649,171 | 628,197 | -20,974 | 0.00 | 0.00 | -0.00 | sell |
| Squarepoint Ops LLC | 32,182 | 0 | -32,182 | 0.00 | 0.00 | -0.00 | sell |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 50,000 | 0 | -50,000 | 0.00 | 0.00 | -0.00 | sell |
| JPMORGAN CHASE & CO | 78,895 | 0 | -78,895 | 0.00 | 0.00 | -0.00 | sell |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 140,000 | 0 | -140,000 | 0.01 | 0.00 | -0.01 | sell |
| FMR LLC | 3,345,006 | 3,157,772 | -187,234 | 0.00 | 0.00 | -0.00 | sell |