| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| VANGUARD GROUP INC | 93,723 | 264,211 | +170,488 | 0.00 | 0.00 | +0.00 | buy |
| PFM Health Sciences, LP | 140,513 | 240,513 | +100,000 | 0.03 | 0.05 | +0.02 | buy |
| NORTHERN TRUST CORP | 0 | 57,578 | +57,578 | 0.00 | 0.00 | +0.00 | buy |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0 | 53,168 | +53,168 | 0.00 | 0.00 | +0.00 | buy |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 0 | 50,000 | +50,000 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 500 | 19,496 | +18,996 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 0 | 11,356 | +11,356 | 0.00 | 0.00 | +0.00 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 0 | 11,024 | +11,024 | 0.00 | 0.00 | +0.00 | buy |
| Point72 (DIFC) Ltd | 20,238 | 28,079 | +7,841 | 0.01 | 0.01 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 110,634 | 116,627 | +5,993 | 0.00 | 0.00 | -0.00 | buy |
| STATE STREET CORP | 21,265 | 25,365 | +4,100 | 0.00 | 0.00 | -0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0 | 3,681 | +3,681 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 1,406 | 4,568 | +3,162 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 0 | 1,049 | +1,049 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | 826 | +826 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 0 | 132 | +132 | 0.00 | 0.00 | 0.00 | buy |
| Russell Investments Group, Ltd. | 0 | 49 | +49 | 0.00 | 0.00 | +0.00 | buy |
| EARNED WEALTH ADVISORS, LLC | 0 | 42 | +42 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 618 | 618 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 457 | 457 | 0 | 0.00 | 0.00 | -0.00 | hold |
| RA CAPITAL MANAGEMENT, L.P. | 2,180,631 | 2,180,631 | 0 | 0.11 | 0.09 | -0.02 | hold |
| NORGES BANK | 157,211 | 157,211 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CITADEL ADVISORS LLC | 718,527 | 718,527 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Alyeska Investment Group, L.P. | 300,000 | 300,000 | 0 | 0.01 | 0.01 | -0.00 | hold |
| Sio Capital Management, LLC | 162,058 | 162,058 | 0 | 0.24 | 0.25 | +0.02 | hold |
| Avior Wealth Management, LLC | 122 | 122 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Squarepoint Ops LLC | 31,250 | 31,250 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Ovata Capital Management Ltd | 25,000 | 25,000 | 0 | 0.05 | 0.04 | -0.02 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 22,100 | 22,100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 14,649 | 14,649 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AMALGAMATED BANK | 218 | 218 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Corebridge Financial, Inc. | 3,395 | 3,374 | -21 | 0.00 | 0.00 | -0.00 | sell |
| FMR LLC | 3,338,180 | 3,338,084 | -96 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 3,273 | 2,905 | -368 | 0.00 | 0.00 | +0.00 | sell |
| Cubist Systematic Strategies, LLC | 520 | 0 | -520 | 0.00 | 0.00 | -0.00 | sell |
| WELLINGTON MANAGEMENT GROUP LLP | 948,402 | 947,612 | -790 | 0.00 | 0.00 | -0.00 | sell |
| Walleye Capital LLC | 40,539 | 39,624 | -915 | 0.00 | 0.00 | -0.00 | sell |
| RHUMBLINE ADVISERS | 6,228 | 5,307 | -921 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 28,616 | 26,860 | -1,756 | 0.00 | 0.00 | -0.00 | sell |
| SECTORAL ASSET MANAGEMENT INC | 682,274 | 678,574 | -3,700 | 1.07 | 1.39 | +0.32 | sell |
| Sandia Investment Management LP | 7,500 | 0 | -7,500 | 0.04 | 0.00 | -0.04 | sell |
| BARCLAYS PLC | 17,476 | 8,633 | -8,843 | 0.00 | 0.00 | -0.00 | sell |
| Redmile Group, LLC | 1,034,583 | 1,023,548 | -11,035 | 0.24 | 0.21 | -0.03 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 45,383 | 28,700 | -16,683 | 0.00 | 0.00 | -0.00 | sell |
| Logos Global Management LP | 117,806 | 58,903 | -58,903 | 0.05 | 0.02 | -0.03 | sell |
| Altium Capital Management LLC | 83,149 | 0 | -83,149 | 0.13 | 0.00 | -0.13 | sell |
| Ensign Peak Advisors, Inc | 364,686 | 187,500 | -177,186 | 0.00 | 0.00 | -0.00 | sell |
| ExodusPoint Capital Management, LP | 215,567 | 17,328 | -198,239 | 0.01 | 0.00 | -0.01 | sell |
| MILLENNIUM MANAGEMENT LLC | 234,663 | 0 | -234,663 | 0.00 | 0.00 | -0.00 | sell |