| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| MORGAN STANLEY | 0 | 234,703 | +234,703 | 0.00 | 0.00 | +0.00 | buy |
| Aberdeen Group plc | 0 | 200,000 | +200,000 | 0.00 | 0.00 | +0.00 | buy |
| MARSHALL WACE, LLP | 0 | 110,551 | +110,551 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0 | 103,948 | +103,948 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 0 | 99,082 | +99,082 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 307,938 | 391,646 | +83,708 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 0 | 83,622 | +83,622 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 2,410 | 79,989 | +77,579 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 0 | 73,163 | +73,163 | 0.00 | 0.00 | +0.00 | buy |
| ExodusPoint Capital Management, LP | 0 | 63,778 | +63,778 | 0.00 | 0.00 | +0.00 | buy |
| Laurion Capital Management LP | 0 | 60,400 | +60,400 | 0.00 | 0.01 | +0.01 | buy |
| Man Group plc | 0 | 50,410 | +50,410 | 0.00 | 0.00 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 45,986 | +45,986 | 0.00 | 0.00 | +0.00 | buy |
| 683 Capital Management, LLC | 0 | 43,198 | +43,198 | 0.00 | 0.03 | +0.03 | buy |
| VANGUARD GROUP INC | 1,752,594 | 1,788,152 | +35,558 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 0 | 33,230 | +33,230 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 0 | 30,285 | +30,285 | 0.00 | 0.00 | +0.00 | buy |
| Cubist Systematic Strategies, LLC | 0 | 26,245 | +26,245 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0 | 22,104 | +22,104 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 41,700 | 61,100 | +19,400 | 0.00 | 0.00 | +0.00 | buy |
| Virtu Financial LLC | 0 | 18,418 | +18,418 | 0.00 | 0.01 | +0.01 | buy |
| Walleye Capital LLC | 0 | 17,777 | +17,777 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 0 | 16,670 | +16,670 | 0.00 | 0.00 | +0.00 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 15,005 | +15,005 | 0.00 | 0.01 | +0.01 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 0 | 13,293 | +13,293 | 0.00 | 0.00 | +0.00 | buy |
| Pale Fire Capital SE | 16,575 | 21,573 | +4,998 | 0.00 | 0.02 | +0.02 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 17,700 | 21,700 | +4,000 | 0.00 | 0.00 | +0.00 | buy |
| LAZARD ASSET MANAGEMENT LLC | 0 | 3,983 | +3,983 | 0.00 | 0.00 | +0.00 | buy |
| STIFEL FINANCIAL CORP | 116,900 | 120,400 | +3,500 | 0.00 | 0.00 | +0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 19,212 | 21,315 | +2,103 | 0.00 | 0.00 | +0.00 | buy |
| BVF INC/IL | 2,989,474 | 2,989,474 | 0 | 0.21 | 0.44 | +0.23 | hold |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 88,300 | 88,300 | 0 | 0.01 | 0.01 | +0.01 | hold |
| BAKER BROS. ADVISORS LP | 2,784,792 | 2,784,792 | 0 | 0.04 | 0.18 | +0.14 | hold |
| ATLAS CAPITAL ADVISORS INC. | 896 | 896 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Deer Management Co. LLC | 1,245,505 | 1,245,505 | 0 | 0.39 | 0.94 | +0.55 | hold |
| DC Investments Management, LLC | 35,563 | 35,563 | 0 | 0.11 | 0.21 | +0.10 | hold |
| EcoR1 Capital, LLC | 5,000,000 | 5,000,000 | 0 | 0.44 | 0.76 | +0.32 | hold |
| Waldron Private Wealth LLC | 10,000 | 10,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Alphabet Inc. | 1,077,080 | 1,077,080 | 0 | 0.18 | 0.29 | +0.11 | hold |
| Aries Wealth Management | 10,000 | 10,000 | 0 | 0.01 | 0.02 | +0.01 | hold |
| Privium Fund Management (UK) Ltd | 15,825 | 15,825 | 0 | 0.03 | 0.06 | +0.03 | hold |
| Simplify Asset Management Inc. | 1,046,916 | 1,046,916 | 0 | 0.44 | 0.95 | +0.50 | hold |
| NewEdge Wealth, LLC | 91,463 | 91,463 | 0 | 0.01 | 0.01 | +0.01 | hold |
| DC Funds, LP | 630,000 | 630,000 | 0 | 33.20 | 44.16 | +10.96 | hold |
| Lynx1 Capital Management LP | 5,224,600 | 5,224,600 | 0 | 8.85 | 11.98 | +3.13 | hold |
| NORTHERN TRUST CORP | 71,976 | 71,611 | -365 | 0.00 | 0.00 | +0.00 | sell |
| LETKO, BROSSEAU & ASSOCIATES INC | 32,400 | 20,700 | -11,700 | 0.00 | 0.00 | +0.00 | sell |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 4,000,000 | 3,900,000 | -100,000 | 0.02 | 0.05 | +0.02 | sell |