| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Paradigm Biocapital Advisors LP | 0 | 1,465,334 | +1,465,334 | 0.00 | 1.05 | +1.05 | buy |
| Woodline Partners LP | 0 | 410,000 | +410,000 | 0.00 | 0.04 | +0.04 | buy |
| VANGUARD GROUP INC | 6,440,715 | 6,818,078 | +377,363 | 0.00 | 0.00 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 103,141 | 427,433 | +324,292 | 0.00 | 0.02 | +0.01 | buy |
| ROYCE & ASSOCIATES LP | 0 | 267,612 | +267,612 | 0.00 | 0.05 | +0.05 | buy |
| FEDERATED HERMES, INC. | 492,922 | 737,555 | +244,633 | 0.02 | 0.02 | +0.01 | buy |
| ExodusPoint Capital Management, LP | 0 | 242,457 | +242,457 | 0.00 | 0.05 | +0.05 | buy |
| CITADEL ADVISORS LLC | 89,168 | 310,075 | +220,907 | 0.00 | 0.00 | +0.00 | buy |
| Informed Momentum Co LLC | 0 | 215,763 | +215,763 | 0.00 | 0.58 | +0.58 | buy |
| Invesco Ltd. | 1,126,668 | 1,328,954 | +202,286 | 0.00 | 0.00 | +0.00 | buy |
| GILDER GAGNON HOWE & CO LLC | 3,902,991 | 4,096,051 | +193,060 | 0.59 | 0.84 | +0.25 | buy |
| Qube Research & Technologies Ltd | 0 | 192,219 | +192,219 | 0.00 | 0.00 | +0.00 | buy |
| FIRST TRUST ADVISORS LP | 263,137 | 440,185 | +177,048 | 0.00 | 0.01 | +0.00 | buy |
| TWINBEECH CAPITAL LP | 0 | 167,764 | +167,764 | 0.00 | 0.05 | +0.05 | buy |
| NORGES BANK | 532,793 | 679,320 | +146,527 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 52,455 | 198,359 | +145,904 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 2,789,530 | 2,920,008 | +130,478 | 0.01 | 0.01 | +0.00 | buy |
| Penserra Capital Management LLC | 0 | 118,521 | +118,521 | 0.00 | 0.03 | +0.03 | buy |
| Aberdeen Group plc | 482,074 | 587,540 | +105,466 | 0.01 | 0.02 | +0.01 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 64,101 | 168,624 | +104,523 | 0.00 | 0.00 | +0.00 | buy |
| Phocas Financial Corp. | 0 | 103,999 | +103,999 | 0.00 | 0.25 | +0.25 | buy |
| MYDA Advisors LLC | 200,000 | 290,000 | +90,000 | 0.80 | 1.61 | +0.81 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 2,472,730 | 2,546,947 | +74,217 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 0 | 73,676 | +73,676 | 0.00 | 0.06 | +0.06 | buy |
| TWO SIGMA ADVISERS, LP | 0 | 70,800 | +70,800 | 0.00 | 0.00 | +0.00 | buy |
| Virtu Financial LLC | 0 | 68,261 | +68,261 | 0.00 | 0.06 | +0.06 | buy |
| TWO SIGMA INVESTMENTS, LP | 84,844 | 151,569 | +66,725 | 0.00 | 0.01 | +0.00 | buy |
| Engineers Gate Manager LP | 0 | 66,123 | +66,123 | 0.00 | 0.02 | +0.02 | buy |
| READYSTATE ASSET MANAGEMENT LP | 0 | 60,200 | +60,200 | 0.00 | 0.05 | +0.05 | buy |
| THOROUGHBRED FINANCIAL SERVICES, LLC | 0 | 59,940 | +59,940 | 0.00 | 0.06 | +0.06 | buy |
| RAYMOND JAMES FINANCIAL INC | 0 | 58,046 | +58,046 | 0.00 | 0.00 | +0.00 | buy |
| MARSHALL WACE, LLP | 0 | 57,908 | +57,908 | 0.00 | 0.00 | +0.00 | buy |
| COOKSON PEIRCE & CO INC | 0 | 57,613 | +57,613 | 0.00 | 0.05 | +0.05 | buy |
| Scientech Research LLC | 0 | 55,205 | +55,205 | 0.00 | 0.23 | +0.23 | buy |
| ESSEX INVESTMENT MANAGEMENT CO LLC | 142,823 | 190,638 | +47,815 | 0.36 | 0.62 | +0.26 | buy |
| AQR CAPITAL MANAGEMENT LLC | 204,480 | 248,196 | +43,716 | 0.00 | 0.00 | +0.00 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 109,731 | 152,861 | +43,130 | 0.00 | 0.01 | +0.00 | buy |
| Brevan Howard Capital Management LP | 0 | 40,618 | +40,618 | 0.00 | 0.02 | +0.02 | buy |
| ALGERT GLOBAL LLC | 80,790 | 120,880 | +40,090 | 0.03 | 0.05 | +0.02 | buy |
| SEI INVESTMENTS CO | 0 | 39,350 | +39,350 | 0.00 | 0.00 | +0.00 | buy |
| TUDOR INVESTMENT CORP ET AL | 64,334 | 103,373 | +39,039 | 0.01 | 0.01 | +0.00 | buy |
| FRED ALGER MANAGEMENT, LLC | 0 | 36,313 | +36,313 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 42,349 | 77,940 | +35,591 | 0.00 | 0.00 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 42,258 | 69,694 | +27,436 | 0.01 | 0.01 | +0.01 | buy |
| Jump Financial, LLC | 15,126 | 42,000 | +26,874 | 0.00 | 0.01 | +0.01 | buy |
| Perpetual Ltd | 0 | 26,520 | +26,520 | 0.00 | 0.01 | +0.01 | buy |
| Silverleafe Capital Partners, LLC | 0 | 26,208 | +26,208 | 0.00 | 0.14 | +0.14 | buy |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 11,399,138 | 11,422,978 | +23,840 | 5.88 | 7.23 | +1.35 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 25,167 | 48,670 | +23,503 | 0.00 | 0.00 | +0.00 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 0 | 23,085 | +23,085 | 0.00 | 0.04 | +0.04 | buy |
| IEQ CAPITAL, LLC | 0 | 22,082 | +22,082 | 0.00 | 0.00 | +0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 0 | 21,906 | +21,906 | 0.00 | 0.03 | +0.03 | buy |
| OXFORD ASSET MANAGEMENT LLP | 0 | 21,324 | +21,324 | 0.00 | 0.15 | +0.15 | buy |
| AMERICAN CENTURY COMPANIES INC | 1,631,226 | 1,652,492 | +21,266 | 0.01 | 0.02 | +0.00 | buy |
| Cerity Partners LLC | 0 | 19,354 | +19,354 | 0.00 | 0.00 | +0.00 | buy |
| Rockefeller Capital Management L.P. | 0 | 18,457 | +18,457 | 0.00 | 0.00 | +0.00 | buy |
| FIDUCIARY TRUST CO | 0 | 16,156 | +16,156 | 0.00 | 0.00 | +0.00 | buy |
| Entropy Technologies, LP | 0 | 15,744 | +15,744 | 0.00 | 0.02 | +0.02 | buy |
| Pathstone Holdings, LLC | 0 | 15,523 | +15,523 | 0.00 | 0.00 | +0.00 | buy |
| GK Wealth Management LLC | 0 | 14,667 | +14,667 | 0.00 | 0.29 | +0.29 | buy |
| KESTRA PRIVATE WEALTH SERVICES, LLC | 0 | 14,158 | +14,158 | 0.00 | 0.00 | +0.00 | buy |
| Massar Capital Management, LP | 0 | 14,000 | +14,000 | 0.00 | 0.26 | +0.26 | buy |
| Legato Capital Management LLC | 42,771 | 56,717 | +13,946 | 0.08 | 0.12 | +0.04 | buy |
| CIBC WORLD MARKETS CORP | 10,059 | 23,852 | +13,793 | 0.00 | 0.00 | +0.00 | buy |
| Virtus Investment Advisers, LLC | 0 | 13,401 | +13,401 | 0.00 | 0.06 | +0.06 | buy |
| Vontobel Holding Ltd. | 0 | 13,356 | +13,356 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 168,052 | 181,074 | +13,022 | 0.00 | 0.00 | +0.00 | buy |
| FOX RUN MANAGEMENT, L.L.C. | 16,946 | 29,967 | +13,021 | 0.04 | 0.07 | +0.03 | buy |
| CANADA LIFE ASSURANCE Co | 0 | 12,816 | +12,816 | 0.00 | 0.00 | +0.00 | buy |
| TOWNSQUARE CAPITAL LLC | 0 | 12,194 | +12,194 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 105,441 | 116,476 | +11,035 | 0.00 | 0.00 | +0.00 | buy |
| Quadrature Capital Ltd | 0 | 11,026 | +11,026 | 0.00 | 0.00 | +0.00 | buy |
| Graham Capital Management, L.P. | 26,837 | 37,617 | +10,780 | 0.01 | 0.02 | +0.01 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 11,099 | 21,799 | +10,700 | 0.00 | 0.00 | +0.00 | buy |
| Baader Bank Aktiengesellschaft | 0 | 10,000 | +10,000 | 0.00 | 0.02 | +0.02 | buy |
| State of Wyoming | 4,028 | 13,232 | +9,204 | 0.01 | 0.03 | +0.02 | buy |
| Allostery Investments LP | 0 | 7,500 | +7,500 | 0.00 | 0.17 | +0.17 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 50,956 | 58,093 | +7,137 | 0.00 | 0.00 | +0.00 | buy |
| NKCFO LLC | 0 | 7,000 | +7,000 | 0.00 | 0.05 | +0.05 | buy |
| Advisors Asset Management, Inc. | 22,339 | 28,187 | +5,848 | 0.01 | 0.01 | +0.00 | buy |
| VIRTUS ADVISERS, LLC | 5,803 | 11,606 | +5,803 | 0.03 | 0.12 | +0.08 | buy |
| KBC Group NV | 0 | 5,368 | +5,368 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 5,998 | 11,331 | +5,333 | 0.00 | 0.00 | +0.00 | buy |
| C M BIDWELL & ASSOCIATES LTD | 0 | 5,285 | +5,285 | 0.00 | 0.05 | +0.05 | buy |
| Diametric Capital, LP | 20,370 | 24,344 | +3,974 | 0.19 | 0.45 | +0.26 | buy |
| Point72 Hong Kong Ltd | 0 | 3,280 | +3,280 | 0.00 | 0.00 | +0.00 | buy |
| LVW Advisors, LLC | 11,936 | 14,466 | +2,530 | 0.02 | 0.03 | +0.01 | buy |
| Police & Firemen's Retirement System of New Jersey | 21,359 | 23,799 | +2,440 | 0.00 | 0.00 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 111,160 | 113,360 | +2,200 | 0.00 | 0.00 | +0.00 | buy |
| COLDSTREAM CAPITAL MANAGEMENT INC | 0 | 2,169 | +2,169 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 69,354 | 71,417 | +2,063 | 0.00 | 0.00 | +0.00 | buy |
| TOCQUEVILLE ASSET MANAGEMENT L.P. | 14,200 | 16,200 | +2,000 | 0.00 | 0.00 | +0.00 | buy |
| Larson Financial Group LLC | 0 | 1,127 | +1,127 | 0.00 | 0.00 | +0.00 | buy |
| SBI Securities Co., Ltd. | 242 | 1,337 | +1,095 | 0.00 | 0.00 | +0.00 | buy |
| AMALGAMATED BANK | 2,670 | 3,723 | +1,053 | 0.00 | 0.00 | +0.00 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 28,780 | 29,697 | +917 | 0.00 | 0.00 | +0.00 | buy |
| Walleye Capital LLC | 0 | 719 | +719 | 0.00 | 0.00 | +0.00 | buy |
| NewEdge Advisors, LLC | 0 | 700 | +700 | 0.00 | 0.00 | +0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 592,565 | 593,195 | +630 | 0.01 | 0.01 | +0.00 | buy |
| AdvisorNet Financial, Inc | 0 | 577 | +577 | 0.00 | 0.00 | +0.00 | buy |