| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 10,805,129 | 10,805,129 | 0 | 0.33 | 0.30 | -0.03 | hold |
| TANG CAPITAL MANAGEMENT LLC | 7,055,576 | 7,055,576 | 0 | 0.72 | 0.59 | -0.13 | hold |
| BlackRock, Inc. | 4,529,416 | 4,153,845 | -375,571 | 0.00 | 0.00 | -0.00 | sell |
| Samsara BioCapital, LLC | 3,768,035 | 3,768,035 | 0 | 1.24 | 1.28 | +0.04 | hold |
| NEA Management Company, LLC | 3,568,781 | 3,568,781 | 0 | 0.51 | 0.45 | -0.06 | hold |
| SR ONE CAPITAL MANAGEMENT, LP | 3,333,333 | 3,333,333 | 0 | 1.58 | 1.20 | -0.38 | hold |
| CITADEL ADVISORS LLC | 3,508,493 | 3,297,824 | -210,669 | 0.01 | 0.00 | -0.00 | sell |
| VANGUARD GROUP INC | 2,525,107 | 2,554,282 | +29,175 | 0.00 | 0.00 | -0.00 | buy |
| Alyeska Investment Group, L.P. | 2,064,956 | 2,084,696 | +19,740 | 0.02 | 0.01 | -0.00 | buy |
| WASATCH ADVISORS LP | 2,066,010 | 1,786,214 | -279,796 | 0.02 | 0.02 | -0.01 | sell |
| Monaco Asset Management SAM | 813,116 | 1,583,372 | +770,256 | 0.76 | 1.00 | +0.24 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,198,313 | 1,208,378 | +10,065 | 0.00 | 0.00 | -0.00 | buy |
| STATE STREET CORP | 1,117,902 | 1,137,942 | +20,040 | 0.00 | 0.00 | -0.00 | buy |
| Affinity Asset Advisors, LLC | 800,000 | 800,000 | 0 | 0.23 | 0.20 | -0.03 | hold |
| Blackstone Inc. | 747,044 | 747,044 | 0 | 0.01 | 0.01 | -0.00 | hold |
| BANK OF AMERICA CORP /DE/ | 809,366 | 742,718 | -66,648 | 0.00 | 0.00 | -0.00 | sell |
| AWM Investment Company, Inc. | 1,000,000 | 700,000 | -300,000 | 0.25 | 0.13 | -0.12 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 811,572 | 696,372 | -115,200 | 0.00 | 0.00 | -0.00 | sell |
| Peapod Lane Capital LLC | 598,245 | 663,850 | +65,605 | 1.24 | 1.10 | -0.14 | buy |
| GOLDMAN SACHS GROUP INC | 681,068 | 593,799 | -87,269 | 0.00 | 0.00 | -0.00 | sell |
| JPMORGAN CHASE & CO | 1,432,558 | 578,012 | -854,546 | 0.00 | 0.00 | -0.00 | sell |
| Woodline Partners LP | 500,166 | 500,166 | 0 | 0.01 | 0.00 | -0.00 | hold |
| ACADIAN ASSET MANAGEMENT LLC | 629,378 | 475,887 | -153,491 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 471,823 | 462,169 | -9,654 | 0.00 | 0.00 | -0.00 | sell |
| AQR CAPITAL MANAGEMENT LLC | 672,078 | 449,518 | -222,560 | 0.00 | 0.00 | -0.00 | sell |
| ROYAL BANK OF CANADA | 0 | 406,072 | +406,072 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 496,187 | 364,218 | -131,969 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 246,863 | 280,312 | +33,449 | 0.00 | 0.00 | -0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 216,438 | 271,962 | +55,524 | 0.00 | 0.00 | -0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 222,113 | 231,081 | +8,968 | 0.00 | 0.00 | -0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 147,551 | 161,776 | +14,225 | 0.00 | 0.00 | -0.00 | buy |
| Samalin Investment Counsel, LLC | 153,425 | 156,425 | +3,000 | 0.11 | 0.10 | -0.01 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 82,240 | 149,530 | +67,290 | 0.00 | 0.00 | +0.00 | buy |
| STIFEL FINANCIAL CORP | 115,999 | 132,496 | +16,497 | 0.00 | 0.00 | -0.00 | buy |
| Nuveen, LLC | 140,113 | 130,739 | -9,374 | 0.00 | 0.00 | -0.00 | sell |
| Bank of New York Mellon Corp | 130,313 | 122,834 | -7,479 | 0.00 | 0.00 | -0.00 | sell |
| FMR LLC | 54,976 | 116,138 | +61,162 | 0.00 | 0.00 | +0.00 | buy |
| PANAGORA ASSET MANAGEMENT INC | 0 | 114,266 | +114,266 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 69,396 | 99,297 | +29,901 | 0.00 | 0.00 | +0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 96,838 | 98,097 | +1,259 | 0.00 | 0.00 | -0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 80,690 | 89,870 | +9,180 | 0.00 | 0.00 | -0.00 | buy |
| TWO SIGMA ADVISERS, LP | 120,300 | 88,400 | -31,900 | 0.00 | 0.00 | -0.00 | sell |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 87,800 | 87,800 | 0 | 0.00 | 0.00 | -0.00 | hold |
| IEQ CAPITAL, LLC | 63,764 | 81,917 | +18,153 | 0.00 | 0.00 | -0.00 | buy |
| RHUMBLINE ADVISERS | 78,185 | 78,522 | +337 | 0.00 | 0.00 | -0.00 | buy |
| HSBC HOLDINGS PLC | 73,805 | 67,193 | -6,612 | 0.00 | 0.00 | -0.00 | sell |
| THRIVENT FINANCIAL FOR LUTHERANS | 103,551 | 63,143 | -40,408 | 0.00 | 0.00 | -0.00 | sell |
| DEUTSCHE BANK AG\ | 58,812 | 58,812 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CWM, LLC | 28,157 | 34,758 | +6,601 | 0.00 | 0.00 | -0.00 | buy |
| Cerity Partners LLC | 29,770 | 33,676 | +3,906 | 0.00 | 0.00 | -0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 28,792 | 32,197 | +3,405 | 0.00 | 0.00 | -0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 31,705 | 30,379 | -1,326 | 0.00 | 0.00 | -0.00 | sell |
| Vanguard Personalized Indexing Management, LLC | 40,363 | 28,030 | -12,333 | 0.00 | 0.00 | -0.00 | sell |
| Forefront Analytics, LLC | 29,191 | 27,979 | -1,212 | 0.06 | 0.02 | -0.04 | sell |
| BANK OF MONTREAL /CAN/ | 37,386 | 27,843 | -9,543 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 37,824 | 26,755 | -11,069 | 0.00 | 0.00 | -0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 23,958 | 25,196 | +1,238 | 0.00 | 0.00 | -0.00 | buy |
| SEI INVESTMENTS CO | 22,788 | 22,898 | +110 | 0.00 | 0.00 | -0.00 | buy |
| Savant Capital, LLC | 0 | 21,986 | +21,986 | 0.00 | 0.00 | +0.00 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 17,365 | 21,620 | +4,255 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 10,286 | 20,359 | +10,073 | 0.00 | 0.00 | +0.00 | buy |
| SG Americas Securities, LLC | 23,731 | 17,522 | -6,209 | 0.00 | 0.00 | -0.00 | sell |
| China Universal Asset Management Co., Ltd. | 14,155 | 14,252 | +97 | 0.00 | 0.00 | -0.00 | buy |
| ProShare Advisors LLC | 14,637 | 13,617 | -1,020 | 0.00 | 0.00 | -0.00 | sell |
| Mariner, LLC | 12,861 | 13,104 | +243 | 0.00 | 0.00 | -0.00 | buy |
| Pallas Capital Advisors LLC | 13,141 | 12,836 | -305 | 0.00 | 0.00 | -0.00 | sell |
| DLK Investment Management, LLC | 0 | 11,320 | +11,320 | 0.00 | 0.01 | +0.01 | buy |
| Merit Financial Group, LLC | 0 | 10,668 | +10,668 | 0.00 | 0.00 | +0.00 | buy |
| Police & Firemen's Retirement System of New Jersey | 10,638 | 10,638 | 0 | 0.00 | 0.00 | -0.00 | hold |
| UPTICK PARTNERS, LLC | 10,450 | 10,450 | 0 | 0.01 | 0.00 | -0.00 | hold |
| MERCER GLOBAL ADVISORS INC /ADV | 0 | 10,082 | +10,082 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 8,455 | 8,455 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Caitong International Asset Management Co., Ltd | 4,877 | 6,091 | +1,214 | 0.01 | 0.01 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 5,184 | 5,184 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SIMPLEX TRADING, LLC | 37,239 | 5,064 | -32,175 | 0.00 | 0.00 | -0.00 | sell |
| Founders Capital Management | 5,000 | 5,000 | 0 | 0.01 | 0.00 | -0.00 | hold |
| Legal & General Group Plc | 4,567 | 4,567 | 0 | 0.00 | 0.00 | -0.00 | hold |
| FEDERATED HERMES, INC. | 5,366 | 3,805 | -1,561 | 0.00 | 0.00 | -0.00 | sell |
| Mirae Asset Global Investments Co., Ltd. | 2,330 | 2,741 | +411 | 0.00 | 0.00 | -0.00 | buy |
| GROUP ONE TRADING LLC | 1,295 | 2,320 | +1,025 | 0.00 | 0.00 | +0.00 | buy |
| AMALGAMATED BANK | 1,826 | 1,826 | 0 | 0.00 | 0.00 | -0.00 | hold |
| EverSource Wealth Advisors, LLC | 1,062 | 1,768 | +706 | 0.00 | 0.00 | +0.00 | buy |
| GF FUND MANAGEMENT CO. LTD. | 1,751 | 1,751 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Sterling Capital Management LLC | 951 | 1,418 | +467 | 0.00 | 0.00 | +0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 506 | 1,071 | +565 | 0.00 | 0.00 | +0.00 | buy |
| Red Tortoise LLC | 801 | 801 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Physician Wealth Advisors, Inc. | 667 | 667 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Russell Investments Group, Ltd. | 2,019 | 435 | -1,584 | 0.00 | 0.00 | -0.00 | sell |
| NATIONAL BANK OF CANADA /FI/ | 299 | 299 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MARK SHEPTOFF FINANCIAL PLANNING, LLC | 200 | 200 | 0 | 0.00 | 0.00 | -0.00 | hold |
| True Wealth Design, LLC | 8 | 164 | +156 | 0.00 | 0.00 | +0.00 | buy |
| IFP Advisors, Inc | 0 | 117 | +117 | 0.00 | 0.00 | +0.00 | buy |
| SBI Securities Co., Ltd. | 104 | 104 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MAI Capital Management | 100 | 100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Federation des caisses Desjardins du Quebec | 100 | 100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Clearstead Advisors, LLC | 0 | 11 | +11 | 0.00 | 0.00 | +0.00 | buy |
| Farther Finance Advisors, LLC | 1 | 1 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ORBIMED ADVISORS LLC | 821,400 | 0 | -821,400 | 0.04 | 0.00 | -0.04 | sell |
| CIBC WORLD MARKETS CORP | 11,741 | 0 | -11,741 | 0.00 | 0.00 | -0.00 | sell |
| VOYA INVESTMENT MANAGEMENT LLC | 15,606 | 0 | -15,606 | 0.00 | 0.00 | -0.00 | sell |