| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 10,805,129 | 10,805,129 | 0 | 0.24 | 0.27 | +0.02 | hold |
| BlackRock, Inc. | 4,508,473 | 6,300,212 | +1,791,739 | 0.00 | 0.00 | +0.00 | buy |
| NEA Management Company, LLC | 3,568,781 | 3,568,781 | 0 | 0.43 | 0.64 | +0.21 | hold |
| Samsara BioCapital, LLC | 3,507,666 | 3,507,666 | 0 | 0.72 | 0.82 | +0.10 | hold |
| SR ONE CAPITAL MANAGEMENT, LP | 3,333,333 | 3,333,333 | 0 | 0.77 | 0.91 | +0.14 | hold |
| Monaco Asset Management SAM | 2,521,932 | 2,373,400 | -148,532 | 1.69 | 2.50 | +0.80 | sell |
| CITADEL ADVISORS LLC | 1,783,994 | 2,174,745 | +390,751 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 2,047,376 | 1,873,293 | -174,083 | 0.00 | 0.00 | +0.00 | sell |
| WASATCH ADVISORS LP | 1,577,847 | 1,577,847 | 0 | 0.02 | 0.03 | +0.01 | hold |
| ACADIAN ASSET MANAGEMENT LLC | 1,259,776 | 1,360,548 | +100,772 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 1,237,474 | 1,286,109 | +48,635 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,267,915 | 1,285,507 | +17,592 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 1,732,372 | 1,177,652 | -554,720 | 0.01 | 0.00 | -0.00 | sell |
| AQR CAPITAL MANAGEMENT LLC | 595,726 | 1,054,251 | +458,525 | 0.00 | 0.00 | +0.00 | buy |
| AWM Investment Company, Inc. | 906,000 | 906,000 | 0 | 0.21 | 0.22 | +0.01 | hold |
| Blackstone Inc. | 0 | 747,044 | +747,044 | 0.00 | 0.01 | +0.01 | buy |
| MARSHALL WACE, LLP | 0 | 673,010 | +673,010 | 0.00 | 0.00 | +0.00 | buy |
| PANAGORA ASSET MANAGEMENT INC | 284,210 | 583,249 | +299,039 | 0.00 | 0.01 | +0.00 | buy |
| JPMORGAN CHASE & CO | 575,001 | 562,980 | -12,021 | 0.00 | 0.00 | +0.00 | sell |
| Peapod Lane Capital LLC | 676,212 | 549,923 | -126,289 | 1.15 | 1.05 | -0.10 | sell |
| Alyeska Investment Group, L.P. | 2,084,840 | 484,840 | -1,600,000 | 0.01 | 0.00 | -0.01 | sell |
| DIMENSIONAL FUND ADVISORS LP | 346,593 | 483,211 | +136,618 | 0.00 | 0.00 | +0.00 | buy |
| Nuveen, LLC | 445,798 | 469,555 | +23,757 | 0.00 | 0.00 | +0.00 | buy |
| T. Rowe Price Investment Management, Inc. | 0 | 455,033 | +455,033 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 385,000 | 433,982 | +48,982 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 417,172 | 371,425 | -45,747 | 0.00 | 0.00 | +0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 145,688 | 323,659 | +177,971 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 153,816 | 289,985 | +136,169 | 0.01 | 0.01 | +0.00 | buy |
| Invesco Ltd. | 150,940 | 207,315 | +56,375 | 0.00 | 0.00 | +0.00 | buy |
| IEQ CAPITAL, LLC | 102,849 | 177,038 | +74,189 | 0.00 | 0.00 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 356,932 | 162,509 | -194,423 | 0.00 | 0.00 | -0.00 | sell |
| Sixth Street Partners Management Company, L.P. | 0 | 130,975 | +130,975 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 130,975 | 130,975 | 0 | 0.00 | 0.00 | +0.00 | hold |
| FMR LLC | 129,099 | 129,942 | +843 | 0.00 | 0.00 | +0.00 | buy |
| Susquehanna Portfolio Strategies, LLC | 61,934 | 126,339 | +64,405 | 0.00 | 0.01 | +0.00 | buy |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 107,800 | 122,800 | +15,000 | 0.00 | 0.01 | +0.00 | buy |
| BARCLAYS PLC | 123,493 | 121,570 | -1,923 | 0.00 | 0.00 | +0.00 | sell |
| Qube Research & Technologies Ltd | 0 | 120,809 | +120,809 | 0.00 | 0.00 | +0.00 | buy |
| MACKENZIE FINANCIAL CORP | 0 | 115,189 | +115,189 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 110,004 | 114,833 | +4,829 | 0.00 | 0.00 | +0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 287,365 | 113,402 | -173,963 | 0.04 | 0.02 | -0.02 | sell |
| JANE STREET GROUP, LLC | 0 | 111,625 | +111,625 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asset Management, L.P. | 60,348 | 106,806 | +46,458 | 0.00 | 0.00 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 89,870 | 100,950 | +11,080 | 0.00 | 0.00 | +0.00 | buy |
| Man Group plc | 152,622 | 100,047 | -52,575 | 0.00 | 0.00 | -0.00 | sell |
| AMERICAN CENTURY COMPANIES INC | 94,851 | 94,851 | 0 | 0.00 | 0.00 | +0.00 | hold |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 0 | 82,658 | +82,658 | 0.00 | 0.00 | +0.00 | buy |
| Mariner, LLC | 34,274 | 78,504 | +44,230 | 0.00 | 0.00 | +0.00 | buy |
| Marquette Asset Management, LLC | 0 | 75,071 | +75,071 | 0.00 | 0.03 | +0.03 | buy |
| STIFEL FINANCIAL CORP | 95,203 | 71,032 | -24,171 | 0.00 | 0.00 | -0.00 | sell |
| Empowered Funds, LLC | 0 | 69,642 | +69,642 | 0.00 | 0.00 | +0.00 | buy |
| HSBC HOLDINGS PLC | 12,034 | 65,994 | +53,960 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 63,500 | 60,473 | -3,027 | 0.00 | 0.00 | +0.00 | sell |
| Rangeley Capital, LLC | 68,000 | 60,000 | -8,000 | 0.15 | 0.16 | +0.00 | sell |
| Cerity Partners LLC | 28,439 | 55,260 | +26,821 | 0.00 | 0.00 | +0.00 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 52,200 | 53,600 | +1,400 | 0.01 | 0.01 | +0.00 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 23,531 | 48,143 | +24,612 | 0.00 | 0.00 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 76,627 | 45,723 | -30,904 | 0.00 | 0.00 | -0.00 | sell |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 68,305 | 40,868 | -27,437 | 0.00 | 0.00 | -0.00 | sell |
| Samalin Investment Counsel, LLC | 93,819 | 40,750 | -53,069 | 0.07 | 0.04 | -0.03 | sell |
| SEI INVESTMENTS CO | 40,046 | 40,046 | 0 | 0.00 | 0.00 | +0.00 | hold |
| MERCER GLOBAL ADVISORS INC /ADV | 11,629 | 33,726 | +22,097 | 0.00 | 0.00 | +0.00 | buy |
| Forefront Analytics, LLC | 43,835 | 28,955 | -14,880 | 0.08 | 0.09 | +0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 28,922 | 28,922 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CANADA PENSION PLAN INVESTMENT BOARD | 14,200 | 28,700 | +14,500 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF MONTREAL /CAN/ | 27,843 | 27,843 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Russell Investments Group, Ltd. | 4,238 | 27,629 | +23,391 | 0.00 | 0.00 | +0.00 | buy |
| Graham Capital Management, L.P. | 15,258 | 23,978 | +8,720 | 0.00 | 0.00 | +0.00 | buy |
| Abel Hall, LLC | 24,113 | 23,245 | -868 | 0.01 | 0.01 | +0.00 | sell |
| SIMPLEX TRADING, LLC | 20,486 | 23,016 | +2,530 | 0.00 | 0.00 | +0.00 | buy |
| Creative Planning | 0 | 21,990 | +21,990 | 0.00 | 0.00 | +0.00 | buy |
| Vanguard Personalized Indexing Management, LLC | 21,353 | 21,062 | -291 | 0.00 | 0.00 | +0.00 | sell |
| CITIGROUP INC | 2,171 | 20,638 | +18,467 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 20,895 | 20,584 | -311 | 0.00 | 0.00 | +0.00 | sell |
| CAPTRUST FINANCIAL ADVISORS | 0 | 18,515 | +18,515 | 0.00 | 0.00 | +0.00 | buy |
| Diversified Trust Co | 0 | 17,363 | +17,363 | 0.00 | 0.00 | +0.00 | buy |
| WINTON GROUP Ltd | 0 | 15,800 | +15,800 | 0.00 | 0.00 | +0.00 | buy |
| Merit Financial Group, LLC | 12,144 | 15,703 | +3,559 | 0.00 | 0.00 | +0.00 | buy |
| BRIGHTON JONES LLC | 0 | 14,751 | +14,751 | 0.00 | 0.00 | +0.00 | buy |
| Focus Partners Wealth | 0 | 12,940 | +12,940 | 0.00 | 0.00 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 12,861 | 12,478 | -383 | 0.00 | 0.00 | +0.00 | sell |
| Arax Advisory Partners | 146 | 12,060 | +11,914 | 0.00 | 0.00 | +0.00 | buy |
| Spark Investment Management LLC | 0 | 11,700 | +11,700 | 0.00 | 0.06 | +0.06 | buy |
| Quadrature Capital Ltd | 0 | 11,508 | +11,508 | 0.00 | 0.00 | +0.00 | buy |
| Pallas Capital Advisors LLC | 0 | 10,851 | +10,851 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 0 | 10,725 | +10,725 | 0.00 | 0.00 | +0.00 | buy |
| Police & Firemen's Retirement System of New Jersey | 10,638 | 10,638 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Neuberger Berman Group LLC | 10,878 | 10,171 | -707 | 0.00 | 0.00 | +0.00 | sell |
| NEW YORK STATE COMMON RETIREMENT FUND | 8,455 | 8,455 | 0 | 0.00 | 0.00 | +0.00 | hold |
| BNP PARIBAS FINANCIAL MARKETS | 11,027 | 8,168 | -2,859 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 5,239 | 8,009 | +2,770 | 0.00 | 0.00 | +0.00 | buy |
| GROUP ONE TRADING LLC | 5,620 | 7,545 | +1,925 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 5,184 | 5,184 | 0 | 0.00 | 0.00 | +0.00 | hold |
| FEDERATED HERMES, INC. | 5,985 | 5,048 | -937 | 0.00 | 0.00 | +0.00 | sell |
| SBI Securities Co., Ltd. | 104 | 4,948 | +4,844 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 4,567 | 4,567 | 0 | 0.00 | 0.00 | +0.00 | hold |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 0 | 3,300 | +3,300 | 0.00 | 0.00 | +0.00 | buy |
| Allworth Financial LP | 687 | 3,282 | +2,595 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 2,217 | 2,464 | +247 | 0.00 | 0.00 | +0.00 | buy |
| Integrated Wealth Concepts LLC | 0 | 2,464 | +2,464 | 0.00 | 0.00 | +0.00 | buy |