| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Curative Ventures V LLC | 1,899,004 | 1,899,004 | 0 | 100.00 | 100.00 | 0.00 | hold |
| Vivo Capital, LLC | 624,340 | 624,338 | -2 | 0.39 | 0.53 | +0.14 | sell |
| CPMG Inc | 410,923 | 410,922 | -1 | 1.36 | 1.61 | +0.25 | sell |
| BML Capital Management, LLC | 0 | 348,735 | +348,735 | 0.00 | 2.52 | +2.52 | buy |
| Cable Car Capital, LP | 258,097 | 258,097 | 0 | 2.06 | 3.91 | +1.85 | hold |
| VANGUARD GROUP INC | 130,102 | 129,513 | -589 | 0.00 | 0.00 | +0.00 | sell |
| Nantahala Capital Management, LLC | 127,292 | 127,292 | 0 | 0.10 | 0.13 | +0.04 | hold |
| RENAISSANCE TECHNOLOGIES LLC | 113,614 | 126,255 | +12,641 | 0.00 | 0.00 | +0.00 | buy |
| MARSHALL WACE, LLP | 60,626 | 60,626 | 0 | 0.00 | 0.00 | +0.00 | hold |
| TWO SIGMA INVESTMENTS, LP | 50,800 | 44,400 | -6,400 | 0.00 | 0.00 | +0.00 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 31,426 | 34,752 | +3,326 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 49,737 | 31,381 | -18,356 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA ADVISERS, LP | 36,789 | 29,489 | -7,300 | 0.00 | 0.00 | +0.00 | sell |
| Squarepoint Ops LLC | 27,836 | 17,367 | -10,469 | 0.00 | 0.00 | -0.00 | sell |
| CITADEL ADVISORS LLC | 28,298 | 15,438 | -12,860 | 0.00 | 0.00 | -0.00 | sell |
| STATE STREET CORP | 12,582 | 11,682 | -900 | 0.00 | 0.00 | +0.00 | sell |
| ACADIAN ASSET MANAGEMENT LLC | 14,014 | 10,244 | -3,770 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 0 | 479 | +479 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 0 | 274 | +274 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 0 | 178 | +178 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 114 | 114 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Frazier Financial Advisors, LLC | 0 | 15 | +15 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 2 | 2 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Qube Research & Technologies Ltd | 0 | 1 | +1 | 0.00 | 0.00 | +0.00 | buy |
| Daiwa Securities Group Inc. | 18 | 0 | -18 | 0.00 | 0.00 | 0.00 | sell |
| Anson Funds Management LP | 17,344 | 0 | -17,344 | 0.03 | 0.00 | -0.03 | sell |
| Covestor Ltd | 1 | 0 | -1 | 0.00 | 0.00 | 0.00 | sell |