| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Curative Ventures V LLC | 1,899,004 | 1,899,004 | 0 | 100.00 | 100.00 | 0.00 | hold |
| Vivo Capital, LLC | 624,338 | 624,339 | +1 | 0.53 | 0.59 | +0.06 | buy |
| CPMG Inc | 410,922 | 410,922 | 0 | 1.61 | 6.32 | +4.71 | hold |
| BML Capital Management, LLC | 348,735 | 391,103 | +42,368 | 2.52 | 2.95 | +0.43 | buy |
| Cable Car Capital, LP | 258,097 | 258,097 | 0 | 3.91 | 2.80 | -1.11 | hold |
| VANGUARD GROUP INC | 129,513 | 129,278 | -235 | 0.00 | 0.00 | -0.00 | sell |
| Nantahala Capital Management, LLC | 127,292 | 127,292 | 0 | 0.13 | 0.13 | -0.00 | hold |
| RENAISSANCE TECHNOLOGIES LLC | 126,255 | 116,255 | -10,000 | 0.00 | 0.00 | -0.00 | sell |
| MARSHALL WACE, LLP | 60,626 | 60,626 | 0 | 0.00 | 0.00 | -0.00 | hold |
| GEODE CAPITAL MANAGEMENT, LLC | 34,752 | 36,393 | +1,641 | 0.00 | 0.00 | -0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 31,381 | 31,631 | +250 | 0.00 | 0.00 | -0.00 | buy |
| TWO SIGMA ADVISERS, LP | 29,489 | 28,089 | -1,400 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 44,400 | 23,790 | -20,610 | 0.00 | 0.00 | -0.00 | sell |
| STATE STREET CORP | 11,682 | 12,182 | +500 | 0.00 | 0.00 | -0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 10,244 | 10,244 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 0 | 625 | +625 | 0.00 | 0.00 | +0.00 | buy |
| JONES FINANCIAL COMPANIES LLLP | 0 | 500 | +500 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 479 | 479 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CITIGROUP INC | 2 | 115 | +113 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 114 | 114 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BNP PARIBAS FINANCIAL MARKETS | 178 | 106 | -72 | 0.00 | 0.00 | -0.00 | sell |
| Frazier Financial Advisors, LLC | 15 | 15 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Qube Research & Technologies Ltd | 1 | 1 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CITADEL ADVISORS LLC | 15,438 | 0 | -15,438 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 274 | 0 | -274 | 0.00 | 0.00 | -0.00 | sell |
| Squarepoint Ops LLC | 17,367 | 0 | -17,367 | 0.00 | 0.00 | -0.00 | sell |