| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| D. E. Shaw & Co., Inc. | 44,390 | 1,580,216 | +1,535,826 | 0.00 | 0.01 | +0.01 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 5,387,783 | 6,617,554 | +1,229,771 | 0.01 | 0.01 | -0.00 | buy |
| STATE STREET CORP | 3,702,196 | 4,894,000 | +1,191,804 | 0.00 | 0.00 | -0.00 | buy |
| ALGERT GLOBAL LLC | 136,350 | 1,215,293 | +1,078,943 | 0.03 | 0.16 | +0.13 | buy |
| GOLDMAN SACHS GROUP INC | 1,475,712 | 2,451,796 | +976,084 | 0.00 | 0.00 | +0.00 | buy |
| BlackRock, Inc. | 5,984,552 | 6,823,973 | +839,421 | 0.00 | 0.00 | -0.00 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 344,315 | 1,051,903 | +707,588 | 0.01 | 0.02 | +0.01 | buy |
| Sixth Street Partners Management Company, L.P. | 0 | 677,823 | +677,823 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 34,012 | 697,694 | +663,682 | 0.00 | 0.01 | +0.00 | buy |
| Candriam S.C.A. | 574,085 | 1,179,768 | +605,683 | 0.04 | 0.06 | +0.02 | buy |
| TWO SIGMA INVESTMENTS, LP | 0 | 603,664 | +603,664 | 0.00 | 0.00 | +0.00 | buy |
| Integral Health Asset Management, LLC | 1,400,000 | 1,900,000 | +500,000 | 0.94 | 0.84 | -0.09 | buy |
| FRANKLIN RESOURCES INC | 1,452,835 | 1,797,377 | +344,542 | 0.00 | 0.00 | -0.00 | buy |
| Squarepoint Ops LLC | 0 | 344,343 | +344,343 | 0.00 | 0.01 | +0.01 | buy |
| DIMENSIONAL FUND ADVISORS LP | 1,471,290 | 1,801,399 | +330,109 | 0.00 | 0.00 | -0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 21,101 | 345,038 | +323,937 | 0.00 | 0.00 | +0.00 | buy |
| SUPERSTRING CAPITAL MANAGEMENT LP | 115,234 | 406,077 | +290,843 | 1.04 | 2.78 | +1.73 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,838,801 | 2,090,089 | +251,288 | 0.00 | 0.00 | -0.00 | buy |
| Blue Owl Capital Holdings LP | 150,000 | 400,000 | +250,000 | 0.51 | 0.66 | +0.15 | buy |
| CITIGROUP INC | 16,994 | 248,757 | +231,763 | 0.00 | 0.00 | +0.00 | buy |
| SPHERA FUNDS MANAGEMENT LTD. | 537,628 | 752,983 | +215,355 | 1.17 | 1.17 | -0.00 | buy |
| FMR LLC | 2,434,080 | 2,635,475 | +201,395 | 0.00 | 0.00 | -0.00 | buy |
| Trexquant Investment LP | 23,972 | 221,819 | +197,847 | 0.00 | 0.01 | +0.01 | buy |
| AQR CAPITAL MANAGEMENT LLC | 170,087 | 358,751 | +188,664 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 43,291 | 217,827 | +174,536 | 0.01 | 0.03 | +0.02 | buy |
| Boxer Capital Management, LLC | 176,500 | 350,000 | +173,500 | 0.29 | 0.29 | -0.01 | buy |
| CITADEL ADVISORS LLC | 2,422,741 | 2,595,299 | +172,558 | 0.02 | 0.02 | -0.01 | buy |
| HRT FINANCIAL LP | 0 | 153,245 | +153,245 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0 | 139,266 | +139,266 | 0.00 | 0.00 | +0.00 | buy |
| Jump Financial, LLC | 0 | 131,400 | +131,400 | 0.00 | 0.01 | +0.01 | buy |
| MORGAN STANLEY | 1,682,523 | 1,794,020 | +111,497 | 0.00 | 0.00 | -0.00 | buy |
| SR ONE CAPITAL MANAGEMENT, LP | 4,514,929 | 4,615,384 | +100,455 | 6.39 | 4.81 | -1.58 | buy |
| NORTHERN TRUST CORP | 710,861 | 806,304 | +95,443 | 0.00 | 0.00 | -0.00 | buy |
| BRAIDWELL LP | 1,128,040 | 1,214,540 | +86,500 | 0.48 | 0.49 | +0.01 | buy |
| WINTON GROUP Ltd | 0 | 83,000 | +83,000 | 0.00 | 0.03 | +0.03 | buy |
| MPM BioImpact LLC | 1,803,945 | 1,882,162 | +78,217 | 1.77 | 1.24 | -0.52 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 605,037 | 677,823 | +72,786 | 0.00 | 0.00 | -0.00 | buy |
| Engineers Gate Manager LP | 0 | 64,052 | +64,052 | 0.00 | 0.01 | +0.01 | buy |
| Caption Management, LLC | 0 | 48,130 | +48,130 | 0.00 | 0.02 | +0.02 | buy |
| WELLS FARGO & COMPANY/MN | 39,108 | 87,009 | +47,901 | 0.00 | 0.00 | +0.00 | buy |
| AXQ CAPITAL, LP | 0 | 36,519 | +36,519 | 0.00 | 0.04 | +0.04 | buy |
| Quadrature Capital Ltd | 0 | 36,296 | +36,296 | 0.00 | 0.00 | +0.00 | buy |
| SG Americas Securities, LLC | 16,093 | 52,089 | +35,996 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 1,043,159 | 1,078,055 | +34,896 | 0.00 | 0.00 | -0.00 | buy |
| Bank of New York Mellon Corp | 190,470 | 220,080 | +29,610 | 0.00 | 0.00 | -0.00 | buy |
| UBS Group AG | 194,689 | 222,923 | +28,234 | 0.00 | 0.00 | -0.00 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 186,099 | 213,373 | +27,274 | 0.00 | 0.00 | -0.00 | buy |
| GROUP ONE TRADING LLC | 100 | 24,162 | +24,062 | 0.00 | 0.01 | +0.01 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 48,369 | 72,060 | +23,691 | 0.00 | 0.00 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 51,333 | 73,878 | +22,545 | 0.00 | 0.00 | +0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 146,804 | 168,628 | +21,824 | 0.00 | 0.00 | -0.00 | buy |
| Nuveen, LLC | 153,022 | 172,167 | +19,145 | 0.00 | 0.00 | -0.00 | buy |
| Jain Global LLC | 0 | 17,637 | +17,637 | 0.00 | 0.00 | +0.00 | buy |
| ALLSTATE CORP | 0 | 16,177 | +16,177 | 0.00 | 0.00 | +0.00 | buy |
| Blueshift Asset Management, LLC | 0 | 15,371 | +15,371 | 0.00 | 0.04 | +0.04 | buy |
| RHUMBLINE ADVISERS | 79,063 | 93,919 | +14,856 | 0.00 | 0.00 | -0.00 | buy |
| DRW Securities, LLC | 0 | 14,312 | +14,312 | 0.00 | 0.01 | +0.01 | buy |
| IEQ CAPITAL, LLC | 0 | 13,444 | +13,444 | 0.00 | 0.00 | +0.00 | buy |
| Creative Planning | 16,466 | 29,903 | +13,437 | 0.00 | 0.00 | +0.00 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 15,432 | 28,682 | +13,250 | 0.00 | 0.00 | +0.00 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 0 | 11,800 | +11,800 | 0.00 | 0.00 | +0.00 | buy |
| Cerity Partners LLC | 0 | 11,106 | +11,106 | 0.00 | 0.00 | +0.00 | buy |
| Brevan Howard Capital Management LP | 19,709 | 30,654 | +10,945 | 0.00 | 0.00 | +0.00 | buy |
| Virtus Investment Advisers, LLC | 29,069 | 39,565 | +10,496 | 0.10 | 0.10 | -0.00 | buy |
| MERCER GLOBAL ADVISORS INC /ADV | 0 | 9,387 | +9,387 | 0.00 | 0.00 | +0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 54,239 | 63,470 | +9,231 | 0.00 | 0.00 | -0.00 | buy |
| TUDOR INVESTMENT CORP ET AL | 33,688 | 42,409 | +8,721 | 0.00 | 0.00 | -0.00 | buy |
| MetLife Investment Management, LLC | 35,689 | 43,840 | +8,151 | 0.00 | 0.00 | -0.00 | buy |
| BARCLAYS PLC | 12,429 | 19,807 | +7,378 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 39,188 | 44,951 | +5,763 | 0.00 | 0.00 | -0.00 | buy |
| SIMPLEX TRADING, LLC | 1,348 | 7,106 | +5,758 | 0.00 | 0.00 | +0.00 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 11,747 | 16,949 | +5,202 | 0.00 | 0.00 | +0.00 | buy |
| Arax Advisory Partners | 215 | 5,249 | +5,034 | 0.00 | 0.00 | +0.00 | buy |
| Police & Firemen's Retirement System of New Jersey | 19,332 | 24,083 | +4,751 | 0.00 | 0.00 | -0.00 | buy |
| China Universal Asset Management Co., Ltd. | 17,809 | 22,153 | +4,344 | 0.02 | 0.01 | -0.00 | buy |
| Quantbot Technologies LP | 0 | 4,280 | +4,280 | 0.00 | 0.00 | +0.00 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 11,222 | 14,826 | +3,604 | 0.00 | 0.00 | -0.00 | buy |
| Integrated Wealth Concepts LLC | 0 | 3,497 | +3,497 | 0.00 | 0.00 | +0.00 | buy |
| Federation des caisses Desjardins du Quebec | 3,000 | 6,000 | +3,000 | 0.00 | 0.00 | +0.00 | buy |
| Pacer Advisors, Inc. | 0 | 1,516 | +1,516 | 0.00 | 0.00 | +0.00 | buy |
| Steward Partners Investment Advisory, LLC | 1,650 | 3,143 | +1,493 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 5,413 | 6,781 | +1,368 | 0.00 | 0.00 | -0.00 | buy |
| Legal & General Group Plc | 29,336 | 30,667 | +1,331 | 0.00 | 0.00 | -0.00 | buy |
| EVENTIDE ASSET MANAGEMENT, LLC | 953,451 | 954,768 | +1,317 | 0.20 | 0.14 | -0.06 | buy |
| Caitong International Asset Management Co., Ltd | 77 | 1,252 | +1,175 | 0.00 | 0.00 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 19,131 | 20,143 | +1,012 | 0.00 | 0.00 | -0.00 | buy |
| TEMA ETFS LLC | 57,227 | 57,977 | +750 | 0.05 | 0.02 | -0.03 | buy |
| IFP Advisors, Inc | 297 | 1,028 | +731 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 298 | 923 | +625 | 0.00 | 0.00 | +0.00 | buy |
| Tidal Investments LLC | 57,602 | 57,977 | +375 | 0.00 | 0.00 | -0.00 | buy |
| Fortitude Family Office, LLC | 0 | 314 | +314 | 0.00 | 0.00 | +0.00 | buy |
| SJS Investment Consulting Inc. | 0 | 140 | +140 | 0.00 | 0.00 | +0.00 | buy |
| Allworth Financial LP | 140 | 279 | +139 | 0.00 | 0.00 | +0.00 | buy |
| State of Wyoming | 0 | 89 | +89 | 0.00 | 0.00 | +0.00 | buy |
| ROTHSCHILD INVESTMENT LLC | 77 | 126 | +49 | 0.00 | 0.00 | +0.00 | buy |
| Covestor Ltd | 0 | 48 | +48 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Advisory Services, LLC | 0 | 46 | +46 | 0.00 | 0.00 | +0.00 | buy |
| Larson Financial Group LLC | 36 | 81 | +45 | 0.00 | 0.00 | +0.00 | buy |
| Stone House Investment Management, LLC | 0 | 18 | +18 | 0.00 | 0.00 | +0.00 | buy |
| Clearstead Advisors, LLC | 0 | 9 | +9 | 0.00 | 0.00 | +0.00 | buy |