| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 218,813 | 325,000 | +106,187 | 0.00 | 0.02 | +0.02 | buy |
| Trexquant Investment LP | 0 | 69,050 | +69,050 | 0.00 | 0.03 | +0.03 | buy |
| Ikarian Capital, LLC | 0 | 64,300 | +64,300 | 0.00 | 0.73 | +0.73 | buy |
| VANGUARD GROUP INC | 63,814 | 96,762 | +32,948 | 0.00 | 0.00 | +0.00 | buy |
| AVANTAX ADVISORY SERVICES, INC. | 0 | 30,570 | +30,570 | 0.00 | 0.01 | +0.01 | buy |
| ROYAL BANK OF CANADA | 0 | 23,008 | +23,008 | 0.00 | 0.00 | +0.00 | buy |
| DRIVE WEALTH MANAGEMENT, LLC | 0 | 23,000 | +23,000 | 0.00 | 0.22 | +0.22 | buy |
| WELLS FARGO & COMPANY/MN | 0 | 21,800 | +21,800 | 0.00 | 0.00 | +0.00 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 0 | 18,543 | +18,543 | 0.00 | 0.02 | +0.02 | buy |
| UBS Group AG | 0 | 15,521 | +15,521 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 0 | 9,582 | +9,582 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 0 | 5,157 | +5,157 | 0.00 | 0.00 | +0.00 | buy |
| BlackRock, Inc. | 9,067 | 13,721 | +4,654 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 24,056 | 27,253 | +3,197 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 11,980 | 14,286 | +2,306 | 0.00 | 0.00 | +0.00 | buy |
| OSAIC HOLDINGS, INC. | 0 | 895 | +895 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 0 | 652 | +652 | 0.00 | 0.00 | +0.00 | buy |
| Spire Wealth Management | 0 | 200 | +200 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 3 | 3 | 0 | 0.00 | 0.00 | +0.00 | hold |
| BAKER BROS. ADVISORS LP | 83,055 | 83,055 | 0 | 0.01 | 0.04 | +0.03 | hold |
| EcoR1 Capital, LLC | 255,573 | 255,573 | 0 | 0.08 | 0.41 | +0.33 | hold |
| Vivo Capital, LLC | 141,879 | 141,879 | 0 | 0.10 | 0.63 | +0.53 | hold |
| HHLR ADVISORS, LTD. | 76,247 | 76,247 | 0 | 0.01 | 0.11 | +0.09 | hold |
| Deep Track Capital, LP | 244,110 | 244,110 | 0 | 0.07 | 0.36 | +0.30 | hold |
| ELEVATION WEALTH PARTNERS, LLC | 4 | 4 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| CWM, LLC | 675 | 0 | -675 | 0.00 | 0.00 | -0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 13,443 | 11,443 | -2,000 | 0.00 | 0.00 | +0.00 | sell |
| Qube Research & Technologies Ltd | 10,947 | 0 | -10,947 | 0.00 | 0.00 | -0.00 | sell |
| SILVERARC CAPITAL MANAGEMENT, LLC | 26,219 | 0 | -26,219 | 0.05 | 0.00 | -0.05 | sell |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 67,096 | 40,096 | -27,000 | 0.01 | 0.04 | +0.03 | sell |
| ACADIAN ASSET MANAGEMENT LLC | 30,597 | 0 | -30,597 | 0.00 | 0.00 | -0.00 | sell |
| Woodline Partners LP | 91,971 | 0 | -91,971 | 0.01 | 0.00 | -0.01 | sell |
| ARMISTICE CAPITAL, LLC | 315,095 | 0 | -315,095 | 0.07 | 0.00 | -0.07 | sell |