| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| FMR LLC | 24,268,223 | 25,696,740 | +1,428,517 | 0.03 | 0.02 | -0.00 | buy |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 5,932,000 | 7,687,638 | +1,755,638 | 1.65 | 1.64 | -0.01 | buy |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 6,608,629 | 7,581,029 | +972,400 | 3.58 | 3.72 | +0.14 | buy |
| HHLR ADVISORS, LTD. | 5,984,550 | 5,984,550 | 0 | 4.19 | 6.47 | +2.28 | hold |
| WESTFIELD CAPITAL MANAGEMENT CO LP | 6,164,677 | 5,763,475 | -401,202 | 0.56 | 0.44 | -0.12 | sell |
| BlackRock, Inc. | 4,276,913 | 4,684,543 | +407,630 | 0.00 | 0.00 | -0.00 | buy |
| Point72 Asset Management, L.P. | 2,784,806 | 3,886,017 | +1,101,211 | 0.09 | 0.12 | +0.03 | buy |
| First Beijing Investment Ltd | 0 | 2,296,335 | +2,296,335 | 0.00 | 1.79 | +1.79 | buy |
| Artisan Partners Limited Partnership | 2,341,074 | 2,254,488 | -86,586 | 0.08 | 0.07 | -0.01 | sell |
| TWO SIGMA INVESTMENTS, LP | 526,070 | 1,890,396 | +1,364,326 | 0.02 | 0.03 | +0.01 | buy |
| Kynam Capital Management, LP | 0 | 1,576,295 | +1,576,295 | 0.00 | 1.81 | +1.81 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 582,154 | 1,527,336 | +945,182 | 0.02 | 0.04 | +0.02 | buy |
| STATE STREET CORP | 1,516,368 | 1,498,372 | -17,996 | 0.00 | 0.00 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 2,174,535 | 1,464,112 | -710,423 | 0.01 | 0.00 | -0.00 | sell |
| Patient Square Capital LP | 0 | 990,000 | +990,000 | 0.00 | 3.18 | +3.18 | buy |
| MATTHEWS INTERNATIONAL CAPITAL MANAGEMENT LLC | 956,824 | 925,920 | -30,904 | 6.31 | 6.80 | +0.48 | sell |
| Hudson Bay Capital Management LP | 575,000 | 876,351 | +301,351 | 0.07 | 0.10 | +0.02 | buy |
| JOHNSON & JOHNSON | 814,586 | 814,586 | 0 | 3.19 | 2.26 | -0.93 | hold |
| IvyRock Asset Management (HK) Ltd | 804,000 | 804,000 | 0 | 9.22 | 8.17 | -1.04 | hold |
| ArrowMark Colorado Holdings LLC | 721,790 | 727,144 | +5,354 | 0.35 | 0.35 | +0.00 | buy |
| Capital International Investors | 941,600 | 647,850 | -293,750 | 0.00 | 0.00 | -0.00 | sell |
| Triata Capital Ltd | 252,600 | 629,914 | +377,314 | 0.67 | 2.07 | +1.40 | buy |
| MORGAN STANLEY | 482,550 | 603,247 | +120,697 | 0.00 | 0.00 | +0.00 | buy |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 480,143 | 574,898 | +94,755 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 555,436 | 550,051 | -5,385 | 0.00 | 0.00 | -0.00 | sell |
| SG Americas Securities, LLC | 371,728 | 535,658 | +163,930 | 0.01 | 0.01 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 402,800 | 521,800 | +119,000 | 0.01 | 0.01 | +0.00 | buy |
| CITADEL ADVISORS LLC | 178,040 | 516,980 | +338,940 | 0.00 | 0.01 | +0.00 | buy |
| Jump Financial, LLC | 523,632 | 516,633 | -6,999 | 0.14 | 0.14 | -0.00 | sell |
| Squarepoint Ops LLC | 409,974 | 479,480 | +69,506 | 0.02 | 0.02 | +0.00 | buy |
| Candriam S.C.A. | 261,815 | 470,292 | +208,477 | 0.03 | 0.04 | +0.02 | buy |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 91,725 | 406,901 | +315,176 | 0.00 | 0.00 | +0.00 | buy |
| SEI INVESTMENTS CO | 103,022 | 324,921 | +221,899 | 0.00 | 0.01 | +0.00 | buy |
| UBS Group AG | 224,612 | 305,214 | +80,602 | 0.00 | 0.00 | +0.00 | buy |
| Empire Life Investments Inc. | 322,936 | 300,958 | -21,978 | 0.40 | 0.35 | -0.05 | sell |
| JPMORGAN CHASE & CO | 945,694 | 288,103 | -657,591 | 0.00 | 0.00 | -0.00 | sell |
| MARSHALL WACE, LLP | 755,953 | 287,123 | -468,830 | 0.02 | 0.01 | -0.01 | sell |
| MILLENNIUM MANAGEMENT LLC | 77,194 | 284,911 | +207,717 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 276,119 | 280,226 | +4,107 | 0.00 | 0.00 | -0.00 | buy |
| Walleye Capital LLC | 299,463 | 235,415 | -64,048 | 0.04 | 0.03 | -0.01 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 264,923 | 234,533 | -30,390 | 0.00 | 0.00 | -0.00 | sell |
| Legal & General Group Plc | 226,950 | 233,868 | +6,918 | 0.00 | 0.00 | -0.00 | buy |
| iA Global Asset Management Inc. | 153,242 | 230,587 | +77,345 | 0.04 | 0.06 | +0.02 | buy |
| Ikarian Capital, LLC | 226,888 | 226,888 | 0 | 0.64 | 0.59 | -0.05 | hold |
| Y-Intercept (Hong Kong) Ltd | 0 | 223,296 | +223,296 | 0.00 | 0.08 | +0.08 | buy |
| HSBC HOLDINGS PLC | 266,134 | 221,475 | -44,659 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 0 | 208,207 | +208,207 | 0.00 | 0.07 | +0.07 | buy |
| Woodline Partners LP | 205,077 | 205,870 | +793 | 0.02 | 0.01 | -0.00 | buy |
| CenterBook Partners LP | 213,024 | 204,603 | -8,421 | 0.23 | 0.20 | -0.03 | sell |
| Russell Investments Group, Ltd. | 175,832 | 193,521 | +17,689 | 0.00 | 0.00 | -0.00 | buy |
| Trexquant Investment LP | 0 | 191,993 | +191,993 | 0.00 | 0.03 | +0.03 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 153,275 | 182,364 | +29,089 | 0.00 | 0.00 | -0.00 | buy |
| BARCLAYS PLC | 273,820 | 179,900 | -93,920 | 0.00 | 0.00 | -0.00 | sell |
| Tidal Investments LLC | 0 | 179,453 | +179,453 | 0.00 | 0.01 | +0.01 | buy |
| BANK OF AMERICA CORP /DE/ | 287,529 | 177,862 | -109,667 | 0.00 | 0.00 | -0.00 | sell |
| Sumitomo Mitsui Trust Group, Inc. | 166,590 | 166,590 | 0 | 0.00 | 0.00 | -0.00 | hold |
| DEUTSCHE BANK AG\ | 157,034 | 165,020 | +7,986 | 0.00 | 0.00 | -0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 163,148 | 163,148 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Swiss National Bank | 161,294 | 142,794 | -18,500 | 0.00 | 0.00 | -0.00 | sell |
| Raiffeisen Bank International AG | 100,000 | 140,000 | +40,000 | 0.03 | 0.03 | +0.01 | buy |
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | 80,363 | 138,046 | +57,683 | 0.02 | 0.03 | +0.01 | buy |
| Pictet Asset Management Holding SA | 111,465 | 98,721 | -12,744 | 0.00 | 0.00 | -0.00 | sell |
| Bank of New York Mellon Corp | 103,375 | 97,613 | -5,762 | 0.00 | 0.00 | -0.00 | sell |
| Nuveen, LLC | 94,586 | 96,786 | +2,200 | 0.00 | 0.00 | -0.00 | buy |
| Mitsubishi UFJ Asset Management Co., Ltd. | 75,078 | 96,781 | +21,703 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 84,981 | 88,564 | +3,583 | 0.00 | 0.00 | -0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 14,883 | 84,765 | +69,882 | 0.03 | 0.10 | +0.07 | buy |
| Rockefeller Capital Management L.P. | 56 | 83,178 | +83,122 | 0.00 | 0.00 | +0.00 | buy |
| Evergreen Quality Fund GP, Ltd. | 122,100 | 81,400 | -40,700 | 0.05 | 0.03 | -0.02 | sell |
| NOMURA HOLDINGS INC | 30,429 | 80,000 | +49,571 | 0.00 | 0.01 | +0.01 | buy |
| CITIGROUP INC | 74,997 | 79,949 | +4,952 | 0.00 | 0.00 | -0.00 | buy |
| AMERIPRISE FINANCIAL INC | 75,062 | 75,439 | +377 | 0.00 | 0.00 | -0.00 | buy |
| ROYAL LONDON ASSET MANAGEMENT LTD | 79,400 | 75,000 | -4,400 | 0.00 | 0.00 | -0.00 | sell |
| NORDEA INVESTMENT MANAGEMENT AB | 73,561 | 71,134 | -2,427 | 0.00 | 0.00 | -0.00 | sell |
| Cinctive Capital Management LP | 0 | 69,586 | +69,586 | 0.00 | 0.08 | +0.08 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 65,826 | 65,826 | 0 | 0.04 | 0.03 | -0.01 | hold |
| TUDOR INVESTMENT CORP ET AL | 53,300 | 55,102 | +1,802 | 0.01 | 0.01 | -0.00 | buy |
| Creative Planning | 17,881 | 55,017 | +37,136 | 0.00 | 0.00 | +0.00 | buy |
| AVIVA PLC | 52,744 | 54,113 | +1,369 | 0.00 | 0.00 | -0.00 | buy |
| GROUP ONE TRADING LLC | 39,976 | 50,910 | +10,934 | 0.03 | 0.03 | +0.00 | buy |
| Headlands Technologies LLC | 34,742 | 49,428 | +14,686 | 0.06 | 0.10 | +0.04 | buy |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 35,841 | 42,727 | +6,886 | 0.00 | 0.00 | +0.00 | buy |
| Handelsbanken Fonder AB | 42,000 | 42,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Rock Springs Capital Management LP | 33,800 | 40,500 | +6,700 | 0.04 | 0.04 | +0.01 | buy |
| GUGGENHEIM CAPITAL LLC | 44,107 | 37,848 | -6,259 | 0.01 | 0.01 | -0.00 | sell |
| Virtus Investment Advisers, LLC | 30,617 | 37,824 | +7,207 | 0.18 | 0.19 | +0.01 | buy |
| Quantinno Capital Management LP | 0 | 37,787 | +37,787 | 0.00 | 0.00 | +0.00 | buy |
| Bellevue Group AG | 63,971 | 35,886 | -28,085 | 0.03 | 0.02 | -0.01 | sell |
| Aquatic Capital Management LLC | 1,432 | 35,314 | +33,882 | 0.00 | 0.02 | +0.02 | buy |
| LMR Partners LLP | 35,000 | 35,000 | 0 | 0.01 | 0.01 | -0.00 | hold |
| Krane Funds Advisors LLC | 28,818 | 31,538 | +2,720 | 0.02 | 0.02 | +0.00 | buy |
| E Fund Management (Hong Kong) Co., Ltd. | 29,922 | 29,922 | 0 | 0.17 | 0.25 | +0.07 | hold |
| E Fund Management Co., Ltd. | 26,132 | 29,922 | +3,790 | 0.04 | 0.02 | -0.03 | buy |
| Aberdeen Group plc | 29,782 | 29,655 | -127 | 0.00 | 0.00 | -0.00 | sell |
| BRITISH COLUMBIA INVESTMENT MANAGEMENT Corp | 28,600 | 28,600 | 0 | 0.00 | 0.00 | -0.00 | hold |
| FEDERATED HERMES, INC. | 16,500 | 28,000 | +11,500 | 0.00 | 0.00 | +0.00 | buy |
| OPPENHEIMER & CO INC | 0 | 26,850 | +26,850 | 0.00 | 0.01 | +0.01 | buy |
| STIFEL FINANCIAL CORP | 26,882 | 26,754 | -128 | 0.00 | 0.00 | -0.00 | sell |
| VOYA INVESTMENT MANAGEMENT LLC | 24,728 | 25,865 | +1,137 | 0.00 | 0.00 | -0.00 | buy |
| PUBLIC SECTOR PENSION INVESTMENT BOARD | 25,789 | 25,789 | 0 | 0.00 | 0.00 | -0.00 | hold |