| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Foresite Capital Management IV, LLC | 8,325,000 | 16,007,999 | +7,682,999 | 4.90 | 7.75 | +2.86 | buy |
| Almitas Capital LLC | 1,050,520 | 2,482,606 | +1,432,086 | 0.15 | 0.44 | +0.30 | buy |
| CITADEL ADVISORS LLC | 3,754,745 | 4,506,857 | +752,112 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 217,285 | 660,899 | +443,614 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 4,137,264 | 4,399,139 | +261,875 | 0.00 | 0.00 | -0.00 | buy |
| Squarepoint Ops LLC | 0 | 198,324 | +198,324 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 204,501 | 387,680 | +183,179 | 0.00 | 0.00 | +0.00 | buy |
| RAYMOND JAMES FINANCIAL INC | 0 | 158,000 | +158,000 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 1,612,146 | 1,768,500 | +156,354 | 0.00 | 0.00 | -0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 19,952 | 174,279 | +154,327 | 0.00 | 0.00 | +0.00 | buy |
| EXCHANGE TRADED CONCEPTS, LLC | 135,050 | 246,349 | +111,299 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 306,400 | 391,200 | +84,800 | 0.00 | 0.00 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 69,220 | 124,696 | +55,476 | 0.00 | 0.00 | +0.00 | buy |
| CIBC WORLD MARKETS CORP | 15,039 | 35,658 | +20,619 | 0.00 | 0.00 | +0.00 | buy |
| IEQ CAPITAL, LLC | 0 | 16,391 | +16,391 | 0.00 | 0.00 | +0.00 | buy |
| GTS SECURITIES LLC | 0 | 13,046 | +13,046 | 0.00 | 0.00 | +0.00 | buy |
| Cerity Partners LLC | 0 | 12,706 | +12,706 | 0.00 | 0.00 | +0.00 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 0 | 12,596 | +12,596 | 0.00 | 0.00 | +0.00 | buy |
| Advisors Asset Management, Inc. | 0 | 11,620 | +11,620 | 0.00 | 0.00 | +0.00 | buy |
| Abel Hall, LLC | 0 | 11,416 | +11,416 | 0.00 | 0.00 | +0.00 | buy |
| Vanguard Personalized Indexing Management, LLC | 22,377 | 32,887 | +10,510 | 0.00 | 0.00 | +0.00 | buy |
| Savant Capital, LLC | 0 | 10,459 | +10,459 | 0.00 | 0.00 | +0.00 | buy |
| Rangeley Capital, LLC | 0 | 10,000 | +10,000 | 0.00 | 0.01 | +0.01 | buy |
| Graham Capital Management, L.P. | 52,136 | 61,609 | +9,473 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 2,487 | 11,553 | +9,066 | 0.00 | 0.00 | +0.00 | buy |
| VSM Wealth Advisory, LLC | 0 | 5,000 | +5,000 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 19,490 | 24,269 | +4,779 | 0.00 | 0.00 | +0.00 | buy |
| GROUP ONE TRADING LLC | 2,000 | 6,001 | +4,001 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 16,095 | 19,335 | +3,240 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 94,320 | 96,453 | +2,133 | 0.00 | 0.00 | -0.00 | buy |
| COLDSTREAM CAPITAL MANAGEMENT INC | 0 | 1,166 | +1,166 | 0.00 | 0.00 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 9,305 | 9,776 | +471 | 0.00 | 0.00 | -0.00 | buy |
| SIMPLEX TRADING, LLC | 617 | 990 | +373 | 0.00 | 0.00 | 0.00 | buy |
| XPONANCE, INC. | 10,998 | 11,269 | +271 | 0.00 | 0.00 | -0.00 | buy |
| EverSource Wealth Advisors, LLC | 0 | 106 | +106 | 0.00 | 0.00 | +0.00 | buy |
| True Wealth Design, LLC | 0 | 60 | +60 | 0.00 | 0.00 | +0.00 | buy |
| MAI Capital Management | 2,000 | 2,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Ameritas Investment Partners, Inc. | 17,114 | 17,114 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TD ASSET MANAGEMENT INC | 1,004,642 | 1,004,642 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 11,644 | 11,644 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 220,790 | 220,790 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PRINCIPAL FINANCIAL GROUP INC | 10,997 | 10,997 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PRUDENTIAL FINANCIAL INC | 48,057 | 48,057 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CANADA PENSION PLAN INVESTMENT BOARD | 588,235 | 588,235 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BBR PARTNERS, LLC | 164,041 | 164,041 | 0 | 0.01 | 0.01 | -0.00 | hold |
| Bank of New York Mellon Corp | 525,782 | 525,782 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TAKEDA PHARMACEUTICAL CO LTD | 823,317 | 823,317 | 0 | 1.98 | 2.74 | +0.75 | hold |
| HSG Holding Ltd | 3,045,997 | 3,045,997 | 0 | 0.07 | 0.09 | +0.01 | hold |
| Daiwa Securities Group Inc. | 917 | 917 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Orland Properties Ltd | 15,093,969 | 15,093,969 | 0 | 14.08 | 9.84 | -4.24 | hold |
| Alphabet Inc. | 5,865,125 | 5,865,125 | 0 | 0.22 | 0.20 | -0.02 | hold |
| Clarius Group, LLC | 399,168 | 399,168 | 0 | 0.02 | 0.01 | -0.00 | hold |
| AE Wealth Management LLC | 25,000 | 25,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| venBio Partners LLC | 7,102,190 | 7,102,190 | 0 | 2.66 | 3.09 | +0.43 | hold |
| Foresite Capital Management V, LLC | 8,133,047 | 8,133,047 | 0 | 4.33 | 4.99 | +0.66 | hold |
| Fortis Capital Management LLC | 12,092 | 12,092 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MWG Management Ltd. | 20,162,332 | 20,162,332 | 0 | 17.35 | 18.48 | +1.13 | hold |
| MIC Capital Management UK LLP | 1,740,569 | 1,740,569 | 0 | 0.16 | 0.19 | +0.03 | hold |
| JOHNSON & JOHNSON | 823,317 | 823,317 | 0 | 0.14 | 0.13 | -0.01 | hold |
| Decheng Capital LLC | 11,909,341 | 11,909,341 | 0 | 1.63 | 1.80 | +0.16 | hold |
| Police & Firemen's Retirement System of New Jersey | 35,001 | 35,001 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SEI INVESTMENTS CO | 55,900 | 55,900 | 0 | 0.00 | 0.00 | -0.00 | hold |
| DIMENSIONAL FUND ADVISORS LP | 13,463 | 13,463 | 0 | 0.00 | 0.00 | -0.00 | hold |
| US BANCORP \DE\ | 1,165 | 1,165 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Legal & General Group Plc | 15,005 | 15,005 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 51,263 | 51,263 | 0 | 0.00 | 0.00 | -0.00 | hold |
| JONES FINANCIAL COMPANIES LLLP | 40,000 | 40,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STRS OHIO | 5,100 | 5,100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AMALGAMATED BANK | 6,005 | 6,005 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MACKENZIE FINANCIAL CORP | 11,205 | 11,205 | 0 | 0.00 | 0.00 | +0.00 | hold |
| TUDOR INVESTMENT CORP ET AL | 124,320 | 124,320 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 49,523 | 49,523 | 0 | 0.00 | 0.00 | -0.00 | hold |
| DEUTSCHE BANK AG\ | 82,441 | 82,441 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Covestor Ltd | 76 | 0 | -76 | 0.00 | 0.00 | 0.00 | sell |
| HSBC HOLDINGS PLC | 18,843 | 18,721 | -122 | 0.00 | 0.00 | -0.00 | sell |
| LAZARD ASSET MANAGEMENT LLC | 182 | 0 | -182 | 0.00 | 0.00 | 0.00 | sell |
| NISA INVESTMENT ADVISORS, LLC | 685 | 500 | -185 | 0.00 | 0.00 | -0.00 | sell |
| China Universal Asset Management Co., Ltd. | 59,205 | 58,603 | -602 | 0.00 | 0.00 | -0.00 | sell |
| Corebridge Financial, Inc. | 79,894 | 78,727 | -1,167 | 0.00 | 0.00 | -0.00 | sell |
| Sterling Capital Management LLC | 5,458 | 2,887 | -2,571 | 0.00 | 0.00 | -0.00 | sell |
| VOYA INVESTMENT MANAGEMENT LLC | 52,935 | 50,329 | -2,606 | 0.00 | 0.00 | -0.00 | sell |
| VICTORY CAPITAL MANAGEMENT INC | 17,845 | 15,148 | -2,697 | 0.00 | 0.00 | -0.00 | sell |
| SHELL ASSET MANAGEMENT CO | 12,810 | 6,401 | -6,409 | 0.00 | 0.00 | -0.00 | sell |
| ProShare Advisors LLC | 58,482 | 47,966 | -10,516 | 0.00 | 0.00 | -0.00 | sell |
| Eagle Bay Advisors LLC | 11,200 | 0 | -11,200 | 0.00 | 0.00 | -0.00 | sell |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 308,551 | 295,647 | -12,904 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 131,877 | 117,905 | -13,972 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 1,310,224 | 1,295,073 | -15,151 | 0.00 | 0.00 | -0.00 | sell |
| Jefferies Financial Group Inc. | 16,316 | 0 | -16,316 | 0.00 | 0.00 | -0.00 | sell |
| Invesco Ltd. | 407,205 | 378,880 | -28,325 | 0.00 | 0.00 | -0.00 | sell |
| VANGUARD GROUP INC | 9,766,083 | 9,737,729 | -28,354 | 0.00 | 0.00 | -0.00 | sell |
| AMERIPRISE FINANCIAL INC | 37,489 | 0 | -37,489 | 0.00 | 0.00 | -0.00 | sell |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 551,851 | 513,828 | -38,023 | 0.00 | 0.00 | -0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,645,787 | 1,604,676 | -41,111 | 0.00 | 0.00 | -0.00 | sell |
| SG Americas Securities, LLC | 116,748 | 71,881 | -44,867 | 0.00 | 0.00 | -0.00 | sell |
| RHUMBLINE ADVISERS | 281,129 | 235,694 | -45,435 | 0.00 | 0.00 | -0.00 | sell |
| STATE STREET CORP | 3,748,673 | 3,702,440 | -46,233 | 0.00 | 0.00 | -0.00 | sell |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 99,307 | 34,307 | -65,000 | 0.00 | 0.00 | -0.00 | sell |
| RPO LLC | 66,378 | 0 | -66,378 | 0.06 | 0.00 | -0.06 | sell |
| BARCLAYS PLC | 258,380 | 183,467 | -74,913 | 0.00 | 0.00 | -0.00 | sell |