| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BANK OF AMERICA CORP /DE/ | 1,035,326 | 1,451,778 | +416,452 | 0.00 | 0.00 | -0.00 | buy |
| MARSHALL WACE, LLP | 0 | 271,197 | +271,197 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 1,109,448 | 1,296,331 | +186,883 | 0.01 | 0.00 | -0.00 | buy |
| COMMONWEALTH EQUITY SERVICES, LLC | 16,909 | 153,777 | +136,868 | 0.00 | 0.00 | +0.00 | buy |
| Almitas Capital LLC | 1,222,945 | 1,353,141 | +130,196 | 0.45 | 0.28 | -0.17 | buy |
| JPMORGAN CHASE & CO | 236,046 | 357,957 | +121,911 | 0.00 | 0.00 | -0.00 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 301,419 | 409,938 | +108,519 | 0.00 | 0.00 | -0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 41,985 | 119,050 | +77,065 | 0.00 | 0.00 | -0.00 | buy |
| Invesco Ltd. | 0 | 73,836 | +73,836 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 684,123 | 718,853 | +34,730 | 0.00 | 0.00 | -0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 740,106 | 770,907 | +30,801 | 0.00 | 0.00 | -0.00 | buy |
| Kazazian Asset Management, LLC | 0 | 19,000 | +19,000 | 0.00 | 0.01 | +0.01 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 13,198 | 32,106 | +18,908 | 0.00 | 0.00 | -0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 14,299 | +14,299 | 0.00 | 0.00 | +0.00 | buy |
| Forum Financial Management, LP | 11,299 | 22,051 | +10,752 | 0.00 | 0.00 | -0.00 | buy |
| MERCER GLOBAL ADVISORS INC /ADV | 0 | 10,077 | +10,077 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 138,470 | 146,977 | +8,507 | 0.00 | 0.00 | -0.00 | buy |
| HC Advisors, LLC | 15,475 | 21,500 | +6,025 | 0.02 | 0.01 | -0.01 | buy |
| Tower Research Capital LLC (TRC) | 5,001 | 10,517 | +5,516 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 2,204 | 6,845 | +4,641 | 0.00 | 0.00 | -0.00 | buy |
| RHUMBLINE ADVISERS | 42,516 | 46,302 | +3,786 | 0.00 | 0.00 | -0.00 | buy |
| FEDERATED HERMES, INC. | 4,483 | 6,541 | +2,058 | 0.00 | 0.00 | -0.00 | buy |
| GROUP ONE TRADING LLC | 15,112 | 17,085 | +1,973 | 0.00 | 0.00 | -0.00 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 39,131 | 40,551 | +1,420 | 0.00 | 0.00 | -0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 18,913 | 19,771 | +858 | 0.00 | 0.00 | -0.00 | buy |
| BANK OF NOVA SCOTIA | 105,306 | 105,858 | +552 | 0.00 | 0.00 | -0.00 | buy |
| EverSource Wealth Advisors, LLC | 0 | 530 | +530 | 0.00 | 0.00 | +0.00 | buy |
| SBI Securities Co., Ltd. | 22 | 126 | +104 | 0.00 | 0.00 | +0.00 | buy |
| Caitong International Asset Management Co., Ltd | 80 | 119 | +39 | 0.00 | 0.00 | -0.00 | buy |
| Ameritas Investment Partners, Inc. | 2,790 | 2,790 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 2,393 | 2,393 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 71,730 | 71,730 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MONETA GROUP INVESTMENT ADVISORS LLC | 15,196 | 15,196 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Sterling Capital Management LLC | 34 | 34 | 0 | 0.00 | 0.00 | -0.00 | hold |
| DekaBank Deutsche Girozentrale | 41,000 | 41,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Lido Advisors, LLC | 13,220 | 13,220 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Aberdeen Group plc | 66,211 | 66,211 | 0 | 0.00 | 0.00 | -0.00 | hold |
| venBio Partners LLC | 9,699,925 | 9,699,925 | 0 | 9.49 | 4.89 | -4.60 | hold |
| Nan Fung Group Holdings Ltd | 41,950 | 41,950 | 0 | 0.06 | 0.02 | -0.04 | hold |
| Privium Fund Management B.V. | 509,059 | 509,059 | 0 | 0.19 | 0.08 | -0.11 | hold |
| JSF Financial, LLC | 17,500 | 17,500 | 0 | 0.01 | 0.00 | -0.00 | hold |
| Bradley & Co. Private Wealth Management, LLC | 1,000 | 1,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Police & Firemen's Retirement System of New Jersey | 6,148 | 6,148 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SEI INVESTMENTS CO | 60,795 | 60,795 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| Legal & General Group Plc | 3,860 | 3,860 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PRICE T ROWE ASSOCIATES INC /MD/ | 10,622 | 10,622 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 12,522 | 12,522 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STRS OHIO | 4,100 | 4,100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AMALGAMATED BANK | 897 | 897 | 0 | 0.00 | 0.00 | +0.00 | hold |
| DEUTSCHE BANK AG\ | 101,113 | 101,113 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NISA INVESTMENT ADVISORS, LLC | 702 | 700 | -2 | 0.00 | 0.00 | -0.00 | sell |
| HSBC HOLDINGS PLC | 16,154 | 16,128 | -26 | 0.00 | 0.00 | -0.00 | sell |
| ROTHSCHILD INVESTMENT LLC | 390 | 225 | -165 | 0.00 | 0.00 | -0.00 | sell |
| Russell Investments Group, Ltd. | 228 | 0 | -228 | 0.00 | 0.00 | -0.00 | sell |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 237 | 0 | -237 | 0.00 | 0.00 | -0.00 | sell |
| Corebridge Financial, Inc. | 17,129 | 16,878 | -251 | 0.00 | 0.00 | -0.00 | sell |
| Bank of New York Mellon Corp | 90,003 | 89,199 | -804 | 0.00 | 0.00 | -0.00 | sell |
| MassMutual Private Wealth & Trust, FSB | 1,270 | 0 | -1,270 | 0.00 | 0.00 | -0.00 | sell |
| SG Americas Securities, LLC | 24,256 | 22,277 | -1,979 | 0.00 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 11,417 | 7,590 | -3,827 | 0.00 | 0.00 | -0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 216,707 | 211,051 | -5,656 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 31,436 | 24,711 | -6,725 | 0.00 | 0.00 | -0.00 | sell |
| Vanguard Personalized Indexing Management, LLC | 43,056 | 34,577 | -8,479 | 0.00 | 0.00 | -0.00 | sell |
| Abel Hall, LLC | 10,406 | 0 | -10,406 | 0.01 | 0.00 | -0.01 | sell |
| SIMPLEX TRADING, LLC | 14,567 | 391 | -14,176 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 65,122 | 48,029 | -17,093 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 343,066 | 318,183 | -24,883 | 0.00 | 0.00 | -0.00 | sell |
| DIMENSIONAL FUND ADVISORS LP | 26,233 | 0 | -26,233 | 0.00 | 0.00 | -0.00 | sell |
| Cubist Systematic Strategies, LLC | 32,021 | 0 | -32,021 | 0.00 | 0.00 | -0.00 | sell |
| Redmile Group, LLC | 3,689,611 | 3,640,834 | -48,777 | 0.43 | 0.21 | -0.22 | sell |
| VANGUARD GROUP INC | 1,887,002 | 1,837,923 | -49,079 | 0.00 | 0.00 | -0.00 | sell |
| BlackRock, Inc. | 2,384,247 | 2,313,800 | -70,447 | 0.00 | 0.00 | -0.00 | sell |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 75,000 | 0 | -75,000 | 0.00 | 0.00 | -0.00 | sell |
| TANG CAPITAL MANAGEMENT LLC | 3,296,883 | 3,158,265 | -138,618 | 0.36 | 0.11 | -0.26 | sell |
| TWO SIGMA ADVISERS, LP | 823,900 | 681,000 | -142,900 | 0.00 | 0.00 | -0.00 | sell |
| BANK OF MONTREAL /CAN/ | 826,582 | 682,394 | -144,188 | 0.00 | 0.00 | -0.00 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 151,620 | 0 | -151,620 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 704,131 | 542,655 | -161,476 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 263,856 | 92,259 | -171,597 | 0.04 | 0.00 | -0.03 | sell |
| D. E. Shaw & Co., Inc. | 255,878 | 75,900 | -179,978 | 0.00 | 0.00 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 569,009 | 373,214 | -195,795 | 0.00 | 0.00 | -0.00 | sell |
| DIADEMA PARTNERS LP | 197,680 | 0 | -197,680 | 0.37 | 0.00 | -0.37 | sell |
| UBS Group AG | 408,056 | 0 | -408,056 | 0.00 | 0.00 | -0.00 | sell |
| MPM BioImpact LLC | 1,391,434 | 550,000 | -841,434 | 0.33 | 0.06 | -0.27 | sell |
| MILLENNIUM MANAGEMENT LLC | 2,129,110 | 944,084 | -1,185,026 | 0.00 | 0.00 | -0.00 | sell |
| FMR LLC | 1,851,556 | 21,988 | -1,829,568 | 0.00 | 0.00 | -0.00 | sell |
| MORGAN STANLEY | 2,499,102 | 0 | -2,499,102 | 0.00 | 0.00 | -0.00 | sell |