| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Almitas Capital LLC | 1,353,141 | 2,538,355 | +1,185,214 | 0.28 | 0.27 | -0.01 | buy |
| GSA CAPITAL PARTNERS LLP | 0 | 81,326 | +81,326 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 14,299 | 85,399 | +71,100 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 0 | 58,307 | +58,307 | 0.00 | 0.00 | +0.00 | buy |
| NAN FUNG TRINITY (HK) Ltd | 0 | 41,950 | +41,950 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | 27,709 | +27,709 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 681,000 | 703,300 | +22,300 | 0.00 | 0.00 | -0.00 | buy |
| Callan Family Office, LLC | 0 | 19,778 | +19,778 | 0.00 | 0.00 | +0.00 | buy |
| Abel Hall, LLC | 0 | 15,209 | +15,209 | 0.00 | 0.00 | +0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 700 | 1,471 | +771 | 0.00 | 0.00 | +0.00 | buy |
| SBI Securities Co., Ltd. | 126 | 422 | +296 | 0.00 | 0.00 | +0.00 | buy |
| Clearstead Advisors, LLC | 0 | 177 | +177 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 530 | 629 | +99 | 0.00 | 0.00 | -0.00 | buy |
| True Wealth Design, LLC | 0 | 15 | +15 | 0.00 | 0.00 | +0.00 | buy |
| FEDERATED HERMES, INC. | 6,541 | 6,541 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MONETA GROUP INVESTMENT ADVISORS LLC | 15,196 | 15,196 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TANG CAPITAL MANAGEMENT LLC | 3,158,265 | 3,158,265 | 0 | 0.11 | 0.07 | -0.04 | hold |
| DekaBank Deutsche Girozentrale | 41,000 | 41,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Lido Advisors, LLC | 13,220 | 13,220 | 0 | 0.00 | 0.00 | -0.00 | hold |
| venBio Partners LLC | 9,699,925 | 9,699,925 | 0 | 4.89 | 3.51 | -1.38 | hold |
| Privium Fund Management B.V. | 509,059 | 509,059 | 0 | 0.08 | 0.05 | -0.04 | hold |
| JSF Financial, LLC | 17,500 | 17,500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Bradley & Co. Private Wealth Management, LLC | 1,000 | 1,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| BANK OF NOVA SCOTIA | 105,858 | 105,858 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Sterling Capital Management LLC | 34 | 0 | -34 | 0.00 | 0.00 | -0.00 | sell |
| Caitong International Asset Management Co., Ltd | 119 | 0 | -119 | 0.00 | 0.00 | -0.00 | sell |
| ROTHSCHILD INVESTMENT LLC | 225 | 0 | -225 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 10,517 | 10,277 | -240 | 0.00 | 0.00 | -0.00 | sell |
| SIMPLEX TRADING, LLC | 391 | 0 | -391 | 0.00 | 0.00 | 0.00 | sell |
| AMALGAMATED BANK | 897 | 0 | -897 | 0.00 | 0.00 | -0.00 | sell |
| HC Advisors, LLC | 21,500 | 20,500 | -1,000 | 0.01 | 0.01 | -0.00 | sell |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 40,551 | 39,279 | -1,272 | 0.00 | 0.00 | -0.00 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 2,393 | 0 | -2,393 | 0.00 | 0.00 | -0.00 | sell |
| Ameritas Investment Partners, Inc. | 2,790 | 0 | -2,790 | 0.00 | 0.00 | -0.00 | sell |
| HSBC HOLDINGS PLC | 16,128 | 12,306 | -3,822 | 0.00 | 0.00 | -0.00 | sell |
| Legal & General Group Plc | 3,860 | 0 | -3,860 | 0.00 | 0.00 | -0.00 | sell |
| FMR LLC | 21,988 | 18,033 | -3,955 | 0.00 | 0.00 | -0.00 | sell |
| STRS OHIO | 4,100 | 0 | -4,100 | 0.00 | 0.00 | -0.00 | sell |
| CWM, LLC | 6,845 | 1,304 | -5,541 | 0.00 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 7,590 | 1,678 | -5,912 | 0.00 | 0.00 | -0.00 | sell |
| Police & Firemen's Retirement System of New Jersey | 6,148 | 0 | -6,148 | 0.00 | 0.00 | -0.00 | sell |
| MERCER GLOBAL ADVISORS INC /ADV | 10,077 | 0 | -10,077 | 0.00 | 0.00 | -0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 10,622 | 0 | -10,622 | 0.00 | 0.00 | -0.00 | sell |
| GROUP ONE TRADING LLC | 17,085 | 5,194 | -11,891 | 0.00 | 0.00 | -0.00 | sell |
| NEW YORK STATE COMMON RETIREMENT FUND | 12,522 | 0 | -12,522 | 0.00 | 0.00 | -0.00 | sell |
| BANK OF MONTREAL /CAN/ | 682,394 | 668,747 | -13,647 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 24,711 | 9,010 | -15,701 | 0.00 | 0.00 | -0.00 | sell |
| Corebridge Financial, Inc. | 16,878 | 0 | -16,878 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 92,259 | 74,770 | -17,489 | 0.00 | 0.00 | -0.00 | sell |
| Kazazian Asset Management, LLC | 19,000 | 0 | -19,000 | 0.01 | 0.00 | -0.01 | sell |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 19,771 | 0 | -19,771 | 0.00 | 0.00 | -0.00 | sell |
| Forum Financial Management, LP | 22,051 | 0 | -22,051 | 0.00 | 0.00 | -0.00 | sell |
| SG Americas Securities, LLC | 22,277 | 0 | -22,277 | 0.00 | 0.00 | -0.00 | sell |
| ACADIAN ASSET MANAGEMENT LLC | 1,296,331 | 1,267,999 | -28,332 | 0.00 | 0.00 | -0.00 | sell |
| INTECH INVESTMENT MANAGEMENT LLC | 32,106 | 0 | -32,106 | 0.00 | 0.00 | -0.00 | sell |
| Vanguard Personalized Indexing Management, LLC | 34,577 | 0 | -34,577 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 48,029 | 10,567 | -37,462 | 0.00 | 0.00 | -0.00 | sell |
| Nan Fung Group Holdings Ltd | 41,950 | 0 | -41,950 | 0.02 | 0.00 | -0.02 | sell |
| RHUMBLINE ADVISERS | 46,302 | 0 | -46,302 | 0.00 | 0.00 | -0.00 | sell |
| SEI INVESTMENTS CO | 60,795 | 0 | -60,795 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 542,655 | 477,934 | -64,721 | 0.00 | 0.00 | -0.00 | sell |
| Aberdeen Group plc | 66,211 | 0 | -66,211 | 0.00 | 0.00 | -0.00 | sell |
| ALLIANCEBERNSTEIN L.P. | 71,730 | 0 | -71,730 | 0.00 | 0.00 | -0.00 | sell |
| AQR CAPITAL MANAGEMENT LLC | 119,050 | 45,583 | -73,467 | 0.00 | 0.00 | -0.00 | sell |
| Invesco Ltd. | 73,836 | 0 | -73,836 | 0.00 | 0.00 | -0.00 | sell |
| D. E. Shaw & Co., Inc. | 75,900 | 0 | -75,900 | 0.00 | 0.00 | -0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 211,051 | 133,433 | -77,618 | 0.00 | 0.00 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 373,214 | 289,693 | -83,521 | 0.00 | 0.00 | -0.00 | sell |
| Bank of New York Mellon Corp | 89,199 | 0 | -89,199 | 0.00 | 0.00 | -0.00 | sell |
| DEUTSCHE BANK AG\ | 101,113 | 0 | -101,113 | 0.00 | 0.00 | -0.00 | sell |
| Qube Research & Technologies Ltd | 146,977 | 44,133 | -102,844 | 0.00 | 0.00 | -0.00 | sell |
| COMMONWEALTH EQUITY SERVICES, LLC | 153,777 | 19,292 | -134,485 | 0.00 | 0.00 | -0.00 | sell |
| Nuveen, LLC | 164,790 | 0 | -164,790 | 0.00 | 0.00 | -0.00 | sell |
| MARSHALL WACE, LLP | 271,197 | 106,280 | -164,917 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 318,183 | 135,909 | -182,274 | 0.00 | 0.00 | -0.00 | sell |
| VANGUARD GROUP INC | 1,837,923 | 1,600,808 | -237,115 | 0.00 | 0.00 | -0.00 | sell |
| Redmile Group, LLC | 3,640,834 | 3,391,455 | -249,379 | 0.21 | 0.15 | -0.06 | sell |
| JPMORGAN CHASE & CO | 357,957 | 0 | -357,957 | 0.00 | 0.00 | -0.00 | sell |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 409,938 | 0 | -409,938 | 0.00 | 0.00 | -0.00 | sell |
| BANK OF AMERICA CORP /DE/ | 1,451,778 | 1,035,127 | -416,651 | 0.00 | 0.00 | -0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 944,084 | 492,614 | -451,470 | 0.00 | 0.00 | -0.00 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 770,907 | 315,421 | -455,486 | 0.00 | 0.00 | -0.00 | sell |
| MPM BioImpact LLC | 550,000 | 0 | -550,000 | 0.06 | 0.00 | -0.06 | sell |
| STATE STREET CORP | 718,853 | 124,232 | -594,621 | 0.00 | 0.00 | -0.00 | sell |
| BlackRock, Inc. | 2,313,800 | 716,297 | -1,597,503 | 0.00 | 0.00 | -0.00 | sell |