| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BRAIDWELL LP | 0 | 3,743,999 | +3,743,999 | 0.00 | 1.00 | +1.00 | buy |
| VANGUARD GROUP INC | 10,650,387 | 11,815,669 | +1,165,282 | 0.00 | 0.00 | -0.00 | buy |
| STATE STREET CORP | 4,903,578 | 6,020,988 | +1,117,410 | 0.00 | 0.00 | -0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 999,639 | +999,639 | 0.00 | 0.02 | +0.02 | buy |
| Point72 Asset Management, L.P. | 0 | 952,019 | +952,019 | 0.00 | 0.02 | +0.02 | buy |
| GOLDMAN SACHS GROUP INC | 983,387 | 1,763,148 | +779,761 | 0.00 | 0.00 | +0.00 | buy |
| Prosight Management, LP | 0 | 450,000 | +450,000 | 0.00 | 1.04 | +1.04 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 323,700 | 763,200 | +439,500 | 0.01 | 0.01 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 312,190 | 741,703 | +429,513 | 0.00 | 0.00 | +0.00 | buy |
| MORGAN STANLEY | 728,704 | 1,157,021 | +428,317 | 0.00 | 0.00 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 138,281 | 538,603 | +400,322 | 0.00 | 0.00 | +0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 0 | 362,450 | +362,450 | 0.00 | 0.00 | +0.00 | buy |
| FEDERATED HERMES, INC. | 0 | 336,490 | +336,490 | 0.00 | 0.01 | +0.01 | buy |
| NORGES BANK | 3,068,973 | 3,392,625 | +323,652 | 0.01 | 0.00 | -0.00 | buy |
| CITIGROUP INC | 146,263 | 414,977 | +268,714 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 1,359,155 | 1,600,814 | +241,659 | 0.00 | 0.00 | -0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 404,916 | 587,690 | +182,774 | 0.01 | 0.01 | +0.00 | buy |
| Finepoint Capital LP | 1,317,870 | 1,490,170 | +172,300 | 5.02 | 3.17 | -1.85 | buy |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 0 | 153,769 | +153,769 | 0.00 | 0.00 | +0.00 | buy |
| BIT Capital GmbH | 0 | 152,439 | +152,439 | 0.00 | 0.11 | +0.11 | buy |
| Rafferty Asset Management, LLC | 327,548 | 464,060 | +136,512 | 0.02 | 0.01 | -0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 2,081,510 | 2,216,793 | +135,283 | 0.00 | 0.00 | -0.00 | buy |
| Man Group plc | 57,347 | 187,982 | +130,635 | 0.00 | 0.00 | +0.00 | buy |
| Integral Health Asset Management, LLC | 600,000 | 725,000 | +125,000 | 0.95 | 0.59 | -0.36 | buy |
| FIRST TRUST ADVISORS LP | 0 | 118,644 | +118,644 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 34,962 | 137,434 | +102,472 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 186,299 | 287,926 | +101,627 | 0.00 | 0.00 | -0.00 | buy |
| ArrowMark Colorado Holdings LLC | 3,914,246 | 4,005,170 | +90,924 | 0.48 | 0.37 | -0.10 | buy |
| JANE STREET GROUP, LLC | 53,238 | 141,439 | +88,201 | 0.00 | 0.00 | +0.00 | buy |
| ALGERT GLOBAL LLC | 232,141 | 301,935 | +69,794 | 0.10 | 0.10 | -0.00 | buy |
| AlphaQuest LLC | 13,380 | 81,295 | +67,915 | 0.03 | 0.12 | +0.09 | buy |
| Russell Investments Group, Ltd. | 114,488 | 179,972 | +65,484 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 329,600 | 394,300 | +64,700 | 0.01 | 0.01 | -0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 87,272 | 149,194 | +61,922 | 0.00 | 0.00 | +0.00 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 11,467 | 68,859 | +57,392 | 0.00 | 0.00 | +0.00 | buy |
| SHERBROOKE PARK ADVISERS LLC | 0 | 44,692 | +44,692 | 0.00 | 0.07 | +0.07 | buy |
| MILLENNIUM MANAGEMENT LLC | 186,966 | 227,906 | +40,940 | 0.00 | 0.00 | -0.00 | buy |
| Bayesian Capital Management, LP | 0 | 38,600 | +38,600 | 0.00 | 0.03 | +0.03 | buy |
| Casdin Capital, LLC | 7,387,943 | 7,423,574 | +35,631 | 8.02 | 4.59 | -3.43 | buy |
| HighTower Advisors, LLC | 212,791 | 247,291 | +34,500 | 0.00 | 0.00 | -0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 877,813 | 912,157 | +34,344 | 0.00 | 0.00 | -0.00 | buy |
| TUDOR INVESTMENT CORP ET AL | 31,314 | 65,441 | +34,127 | 0.00 | 0.01 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 37,638 | 63,720 | +26,082 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 11,069 | 36,331 | +25,262 | 0.03 | 0.04 | +0.01 | buy |
| Brevan Howard Capital Management LP | 0 | 25,108 | +25,108 | 0.00 | 0.02 | +0.02 | buy |
| Dynamic Technology Lab Private Ltd | 20,763 | 44,632 | +23,869 | 0.02 | 0.04 | +0.02 | buy |
| Woodline Partners LP | 250,000 | 273,008 | +23,008 | 0.03 | 0.02 | -0.01 | buy |
| Engineers Gate Manager LP | 27,114 | 49,374 | +22,260 | 0.01 | 0.01 | +0.00 | buy |
| AXQ CAPITAL, LP | 0 | 21,000 | +21,000 | 0.00 | 0.04 | +0.04 | buy |
| EXCHANGE TRADED CONCEPTS, LLC | 14,962 | 34,876 | +19,914 | 0.00 | 0.01 | +0.00 | buy |
| Intellectus Partners, LLC | 49,860 | 69,260 | +19,400 | 0.16 | 0.15 | -0.01 | buy |
| PROFUND ADVISORS LLC | 54,029 | 72,349 | +18,320 | 0.03 | 0.02 | -0.00 | buy |
| Mesirow Financial Investment Management, Inc. | 0 | 17,627 | +17,627 | 0.00 | 0.00 | +0.00 | buy |
| OXFORD ASSET MANAGEMENT LLP | 0 | 16,018 | +16,018 | 0.00 | 0.17 | +0.17 | buy |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 0 | 15,325 | +15,325 | 0.00 | 0.01 | +0.01 | buy |
| CAPSTONE INVESTMENT ADVISORS, LLC | 0 | 14,506 | +14,506 | 0.00 | 0.00 | +0.00 | buy |
| FOX RUN MANAGEMENT, L.L.C. | 12,191 | 26,391 | +14,200 | 0.03 | 0.05 | +0.01 | buy |
| Centiva Capital, LP | 0 | 12,675 | +12,675 | 0.00 | 0.01 | +0.01 | buy |
| MACKENZIE FINANCIAL CORP | 0 | 11,571 | +11,571 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 75,799 | 87,087 | +11,288 | 0.00 | 0.00 | -0.00 | buy |
| MARTINGALE ASSET MANAGEMENT L P | 46,696 | 57,826 | +11,130 | 0.01 | 0.01 | -0.00 | buy |
| China Universal Asset Management Co., Ltd. | 14,257 | 25,210 | +10,953 | 0.03 | 0.03 | -0.00 | buy |
| Virtu Financial LLC | 0 | 10,461 | +10,461 | 0.00 | 0.01 | +0.01 | buy |
| Jump Financial, LLC | 0 | 10,316 | +10,316 | 0.00 | 0.00 | +0.00 | buy |
| Handelsbanken Fonder AB | 29,500 | 39,200 | +9,700 | 0.00 | 0.00 | -0.00 | buy |
| Allspring Global Investments Holdings, LLC | 0 | 9,569 | +9,569 | 0.00 | 0.00 | +0.00 | buy |
| Swiss National Bank | 156,400 | 163,500 | +7,100 | 0.00 | 0.00 | -0.00 | buy |
| TrueMark Investments, LLC | 47,958 | 54,445 | +6,487 | 0.52 | 0.41 | -0.11 | buy |
| WELLS FARGO & COMPANY/MN | 27,849 | 33,531 | +5,682 | 0.00 | 0.00 | -0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 21,922 | 27,421 | +5,499 | 0.02 | 0.02 | -0.00 | buy |
| RHUMBLINE ADVISERS | 151,445 | 156,387 | +4,942 | 0.00 | 0.00 | -0.00 | buy |
| E Fund Management Co., Ltd. | 17,486 | 21,930 | +4,444 | 0.01 | 0.01 | -0.00 | buy |
| NORTHERN TRUST CORP | 824,350 | 828,407 | +4,057 | 0.00 | 0.00 | -0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 51,233 | 54,917 | +3,684 | 0.00 | 0.00 | +0.00 | buy |
| ProShare Advisors LLC | 22,820 | 26,214 | +3,394 | 0.00 | 0.00 | -0.00 | buy |
| Verition Fund Management LLC | 16,170 | 19,394 | +3,224 | 0.00 | 0.00 | -0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 11,501 | 14,550 | +3,049 | 0.00 | 0.00 | -0.00 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 11,089 | 13,939 | +2,850 | 0.00 | 0.00 | -0.00 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 19,165 | 21,514 | +2,349 | 0.00 | 0.00 | -0.00 | buy |
| Pacer Advisors, Inc. | 0 | 2,157 | +2,157 | 0.00 | 0.00 | +0.00 | buy |
| CONGRESS ASSET MANAGEMENT CO | 146,974 | 149,082 | +2,108 | 0.01 | 0.01 | -0.00 | buy |
| AMERICAN INTERNATIONAL GROUP, INC. | 44,876 | 46,686 | +1,810 | 0.00 | 0.00 | -0.00 | buy |
| DEUTSCHE BANK AG\ | 50,367 | 51,615 | +1,248 | 0.00 | 0.00 | -0.00 | buy |
| Cubist Systematic Strategies, LLC | 0 | 1,229 | +1,229 | 0.00 | 0.00 | +0.00 | buy |
| NEOS Investment Management LLC | 22,110 | 22,780 | +670 | 0.02 | 0.01 | -0.01 | buy |
| Arizona State Retirement System | 22,193 | 22,769 | +576 | 0.00 | 0.00 | -0.00 | buy |
| EntryPoint Capital, LLC | 0 | 231 | +231 | 0.00 | 0.00 | +0.00 | buy |
| SIMPLEX TRADING, LLC | 0 | 150 | +150 | 0.00 | 0.00 | +0.00 | buy |
| First Horizon Advisors, Inc. | 647 | 793 | +146 | 0.00 | 0.00 | -0.00 | buy |
| OSAIC HOLDINGS, INC. | 24,231 | 24,373 | +142 | 0.00 | 0.00 | -0.00 | buy |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 18,357 | 18,436 | +79 | 0.00 | 0.00 | -0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 860 | 905 | +45 | 0.00 | 0.00 | -0.00 | buy |
| JANUS HENDERSON GROUP PLC | 37,313 | 37,342 | +29 | 0.00 | 0.00 | -0.00 | buy |
| First Command Advisory Services, Inc. | 0 | 25 | +25 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 0 | 23 | +23 | 0.00 | 0.00 | 0.00 | buy |
| Avior Wealth Management, LLC | 0 | 18 | +18 | 0.00 | 0.00 | +0.00 | buy |
| ROTHSCHILD INVESTMENT LLC | 0 | 15 | +15 | 0.00 | 0.00 | +0.00 | buy |
| Capital Advisors, Ltd. LLC | 87 | 92 | +5 | 0.00 | 0.00 | -0.00 | buy |
| BOSTON FAMILY OFFICE LLC | 12,397 | 12,397 | 0 | 0.01 | 0.01 | -0.00 | hold |
| CANADA LIFE ASSURANCE Co | 8,624 | 8,624 | 0 | 0.00 | 0.00 | -0.00 | hold |