| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| TANG CAPITAL MANAGEMENT LLC | 3,568,058 | 8,068,058 | +4,500,000 | 1.80 | 2.20 | +0.39 | buy |
| BlackRock, Inc. | 11,742,147 | 14,674,262 | +2,932,115 | 0.00 | 0.00 | -0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 1,059,607 | 2,568,384 | +1,508,777 | 0.01 | 0.01 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 1,748,663 | 2,964,997 | +1,216,334 | 0.00 | 0.00 | -0.00 | buy |
| Kynam Capital Management, LP | 0 | 1,000,000 | +1,000,000 | 0.00 | 0.27 | +0.27 | buy |
| STATE STREET CORP | 4,300,216 | 5,279,726 | +979,510 | 0.00 | 0.00 | -0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 671,095 | 1,549,190 | +878,095 | 0.01 | 0.01 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 1,975,465 | 2,705,969 | +730,504 | 0.00 | 0.00 | -0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 692,279 | +692,279 | 0.00 | 0.01 | +0.01 | buy |
| Exome Asset Management LLC | 414,629 | 1,083,487 | +668,858 | 1.98 | 3.36 | +1.37 | buy |
| Candriam S.C.A. | 1,092,705 | 1,729,199 | +636,494 | 0.04 | 0.04 | -0.00 | buy |
| VANGUARD GROUP INC | 14,463,614 | 15,030,209 | +566,595 | 0.00 | 0.00 | -0.00 | buy |
| Trexquant Investment LP | 411,862 | 978,137 | +566,275 | 0.04 | 0.05 | +0.01 | buy |
| Finepoint Capital LP | 1,626,146 | 2,175,646 | +549,500 | 1.40 | 1.03 | -0.37 | buy |
| Parkman Healthcare Partners LLC | 0 | 500,548 | +500,548 | 0.00 | 0.27 | +0.27 | buy |
| ALGERT GLOBAL LLC | 513,277 | 994,923 | +481,646 | 0.10 | 0.10 | -0.00 | buy |
| Schonfeld Strategic Advisors LLC | 0 | 354,500 | +354,500 | 0.00 | 0.01 | +0.01 | buy |
| MORGAN STANLEY | 962,111 | 1,300,770 | +338,659 | 0.00 | 0.00 | -0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 23,392 | 326,134 | +302,742 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 2,732,270 | 3,030,157 | +297,887 | 0.00 | 0.00 | -0.00 | buy |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 53,442 | 346,288 | +292,846 | 0.01 | 0.02 | +0.02 | buy |
| BIT Capital GmbH | 0 | 284,508 | +284,508 | 0.00 | 0.10 | +0.10 | buy |
| Point72 Asset Management, L.P. | 1,349,400 | 1,592,753 | +243,353 | 0.03 | 0.02 | -0.02 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 0 | 239,668 | +239,668 | 0.00 | 0.00 | +0.00 | buy |
| MPM BioImpact LLC | 2,033,041 | 2,268,825 | +235,784 | 2.16 | 1.33 | -0.83 | buy |
| NORTHERN TRUST CORP | 938,266 | 1,169,979 | +231,713 | 0.00 | 0.00 | -0.00 | buy |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 112,048 | 330,699 | +218,651 | 0.02 | 0.03 | +0.01 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 109,912 | 297,165 | +187,253 | 0.06 | 0.10 | +0.04 | buy |
| Man Group plc | 0 | 173,605 | +173,605 | 0.00 | 0.00 | +0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 376,645 | 549,645 | +173,000 | 0.00 | 0.00 | -0.00 | buy |
| UBS Group AG | 191,724 | 343,246 | +151,522 | 0.00 | 0.00 | -0.00 | buy |
| Squarepoint Ops LLC | 25,568 | 162,588 | +137,020 | 0.00 | 0.00 | +0.00 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 32,893 | 161,827 | +128,934 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 87,386 | 205,676 | +118,290 | 0.00 | 0.00 | +0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 15,407 | 129,948 | +114,541 | 0.01 | 0.04 | +0.03 | buy |
| FIRST TRUST ADVISORS LP | 0 | 89,949 | +89,949 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 0 | 87,863 | +87,863 | 0.00 | 0.00 | +0.00 | buy |
| HSBC HOLDINGS PLC | 34,420 | 111,769 | +77,349 | 0.00 | 0.00 | +0.00 | buy |
| Rafferty Asset Management, LLC | 180,030 | 249,561 | +69,531 | 0.00 | 0.00 | -0.00 | buy |
| Russell Investments Group, Ltd. | 11,245 | 79,804 | +68,559 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 251,819 | 313,202 | +61,383 | 0.00 | 0.00 | -0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 220,667 | 272,166 | +51,499 | 0.00 | 0.00 | -0.00 | buy |
| Bank of New York Mellon Corp | 278,707 | 328,897 | +50,190 | 0.00 | 0.00 | -0.00 | buy |
| Nebula Research & Development LLC | 39,584 | 86,641 | +47,057 | 0.03 | 0.04 | +0.01 | buy |
| HighTower Advisors, LLC | 154,920 | 199,743 | +44,823 | 0.00 | 0.00 | -0.00 | buy |
| Aristides Capital LLC | 0 | 43,400 | +43,400 | 0.00 | 0.06 | +0.06 | buy |
| FEDERATED HERMES, INC. | 7,869 | 50,100 | +42,231 | 0.00 | 0.00 | +0.00 | buy |
| Jump Financial, LLC | 101,975 | 138,226 | +36,251 | 0.01 | 0.01 | -0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 42,388 | 76,318 | +33,930 | 0.00 | 0.00 | -0.00 | buy |
| Graham Capital Management, L.P. | 0 | 31,569 | +31,569 | 0.00 | 0.00 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 52,182 | 82,460 | +30,278 | 0.00 | 0.00 | -0.00 | buy |
| Creative Planning | 0 | 29,532 | +29,532 | 0.00 | 0.00 | +0.00 | buy |
| Savant Capital, LLC | 0 | 29,088 | +29,088 | 0.00 | 0.00 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 276,452 | 305,441 | +28,989 | 0.00 | 0.00 | -0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 0 | 28,947 | +28,947 | 0.00 | 0.00 | +0.00 | buy |
| SIMPLEX TRADING, LLC | 20,426 | 47,462 | +27,036 | 0.00 | 0.01 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 614,200 | 638,900 | +24,700 | 0.01 | 0.01 | -0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 82,527 | 106,287 | +23,760 | 0.00 | 0.00 | -0.00 | buy |
| SG Americas Securities, LLC | 55,084 | 77,557 | +22,473 | 0.00 | 0.00 | -0.00 | buy |
| SYON CAPITAL LLC | 0 | 22,157 | +22,157 | 0.00 | 0.01 | +0.01 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 31,890 | 52,770 | +20,880 | 0.00 | 0.00 | -0.00 | buy |
| Mesirow Financial Investment Management, Inc. | 14,536 | 32,916 | +18,380 | 0.00 | 0.00 | +0.00 | buy |
| Vanguard Personalized Indexing Management, LLC | 0 | 17,525 | +17,525 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 61,822 | 78,831 | +17,009 | 0.00 | 0.00 | -0.00 | buy |
| MetLife Investment Management, LLC | 57,689 | 74,166 | +16,477 | 0.00 | 0.00 | -0.00 | buy |
| ProShare Advisors LLC | 26,708 | 42,200 | +15,492 | 0.00 | 0.00 | -0.00 | buy |
| Verition Fund Management LLC | 76,139 | 90,474 | +14,335 | 0.00 | 0.00 | -0.00 | buy |
| RHUMBLINE ADVISERS | 157,912 | 171,444 | +13,532 | 0.00 | 0.00 | -0.00 | buy |
| XTX Topco Ltd | 47,271 | 59,752 | +12,481 | 0.02 | 0.02 | -0.00 | buy |
| PROFUND ADVISORS LLC | 36,133 | 48,539 | +12,406 | 0.01 | 0.01 | -0.00 | buy |
| Atom Investors LP | 0 | 11,765 | +11,765 | 0.00 | 0.01 | +0.01 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 36,176 | 47,645 | +11,469 | 0.00 | 0.00 | -0.00 | buy |
| CIBC WORLD MARKETS CORP | 0 | 11,388 | +11,388 | 0.00 | 0.00 | +0.00 | buy |
| CONGRESS ASSET MANAGEMENT CO | 146,424 | 157,485 | +11,061 | 0.01 | 0.00 | -0.00 | buy |
| TWINBEECH CAPITAL LP | 0 | 10,204 | +10,204 | 0.00 | 0.00 | +0.00 | buy |
| STIFEL FINANCIAL CORP | 0 | 10,200 | +10,200 | 0.00 | 0.00 | +0.00 | buy |
| China Universal Asset Management Co., Ltd. | 25,751 | 35,491 | +9,740 | 0.02 | 0.01 | -0.01 | buy |
| Ensign Peak Advisors, Inc | 55,450 | 64,900 | +9,450 | 0.00 | 0.00 | -0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 223,289 | 232,582 | +9,293 | 0.00 | 0.00 | -0.00 | buy |
| Arizona State Retirement System | 25,190 | 32,737 | +7,547 | 0.00 | 0.00 | -0.00 | buy |
| Corebridge Financial, Inc. | 53,186 | 60,500 | +7,314 | 0.00 | 0.00 | -0.00 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 21,514 | 28,697 | +7,183 | 0.00 | 0.00 | -0.00 | buy |
| FMR LLC | 89,772 | 96,682 | +6,910 | 0.00 | 0.00 | -0.00 | buy |
| NEOS Investment Management LLC | 58,290 | 64,655 | +6,365 | 0.01 | 0.01 | -0.01 | buy |
| THRIVENT FINANCIAL FOR LUTHERANS | 160,458 | 166,668 | +6,210 | 0.00 | 0.00 | -0.00 | buy |
| E Fund Management Co., Ltd. | 11,550 | 17,654 | +6,104 | 0.00 | 0.00 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 21,050 | 27,128 | +6,078 | 0.00 | 0.00 | -0.00 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 208,708 | 214,399 | +5,691 | 0.04 | 0.03 | -0.02 | buy |
| TUDOR INVESTMENT CORP ET AL | 80,683 | 86,357 | +5,674 | 0.01 | 0.00 | -0.00 | buy |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 28,228 | 33,720 | +5,492 | 0.00 | 0.00 | -0.00 | buy |
| Invesco Ltd. | 114,156 | 119,417 | +5,261 | 0.00 | 0.00 | -0.00 | buy |
| GROUP ONE TRADING LLC | 0 | 4,774 | +4,774 | 0.00 | 0.00 | +0.00 | buy |
| Steward Partners Investment Advisory, LLC | 2,500 | 6,500 | +4,000 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 8,970 | 12,730 | +3,760 | 0.00 | 0.00 | -0.00 | buy |
| Sterling Capital Management LLC | 351 | 3,834 | +3,483 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 870 | 4,325 | +3,455 | 0.00 | 0.00 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 215,547 | 218,872 | +3,325 | 0.00 | 0.00 | -0.00 | buy |
| VIRTUS ADVISERS, LLC | 11,781 | 14,873 | +3,092 | 0.04 | 0.03 | -0.01 | buy |
| Brooklyn Investment Group | 0 | 2,801 | +2,801 | 0.00 | 0.00 | +0.00 | buy |
| US BANCORP \DE\ | 1,065 | 3,811 | +2,746 | 0.00 | 0.00 | +0.00 | buy |