| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BIT Capital GmbH | 3,491,234 | 6,348,797 | +2,857,563 | 1.08 | 3.08 | +2.00 | buy |
| Point72 Asset Management, L.P. | 0 | 2,620,878 | +2,620,878 | 0.00 | 0.06 | +0.06 | buy |
| Logos Global Management LP | 0 | 2,250,000 | +2,250,000 | 0.00 | 1.37 | +1.37 | buy |
| BANK OF AMERICA CORP /DE/ | 0 | 2,019,348 | +2,019,348 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 2,583,499 | 4,470,485 | +1,886,986 | 0.01 | 0.05 | +0.04 | buy |
| Candriam S.C.A. | 0 | 1,274,278 | +1,274,278 | 0.00 | 0.08 | +0.08 | buy |
| TANG CAPITAL MANAGEMENT LLC | 4,002,200 | 5,000,000 | +997,800 | 1.12 | 3.21 | +2.09 | buy |
| Woodline Partners LP | 175,439 | 1,086,004 | +910,565 | 0.00 | 0.05 | +0.04 | buy |
| CITADEL ADVISORS LLC | 269,489 | 1,004,880 | +735,391 | 0.00 | 0.01 | +0.01 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 865,354 | 1,431,889 | +566,535 | 0.01 | 0.03 | +0.02 | buy |
| Trexquant Investment LP | 309,283 | 860,158 | +550,875 | 0.01 | 0.08 | +0.06 | buy |
| Blue Owl Capital Holdings LP | 0 | 450,000 | +450,000 | 0.00 | 0.97 | +0.97 | buy |
| Ensign Peak Advisors, Inc | 39,225 | 474,653 | +435,428 | 0.00 | 0.01 | +0.01 | buy |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 68,485 | 384,351 | +315,866 | 0.02 | 0.35 | +0.33 | buy |
| MARSHALL WACE, LLP | 4,038,335 | 4,328,682 | +290,347 | 0.02 | 0.05 | +0.03 | buy |
| STEMPOINT CAPITAL LP | 0 | 284,769 | +284,769 | 0.00 | 0.70 | +0.70 | buy |
| BlackRock, Inc. | 683,241 | 925,391 | +242,150 | 0.00 | 0.00 | +0.00 | buy |
| SILVERARC CAPITAL MANAGEMENT, LLC | 300,000 | 503,382 | +203,382 | 0.20 | 0.79 | +0.60 | buy |
| AdvisorShares Investments LLC | 246,739 | 421,347 | +174,608 | 0.25 | 0.72 | +0.47 | buy |
| JANE STREET GROUP, LLC | 341,821 | 501,930 | +160,109 | 0.00 | 0.00 | +0.00 | buy |
| ARK Investment Management LLC | 3,301,050 | 3,451,965 | +150,915 | 0.14 | 0.32 | +0.18 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 138,480 | +138,480 | 0.00 | 0.00 | +0.00 | buy |
| ALPS ADVISORS INC | 0 | 136,462 | +136,462 | 0.00 | 0.01 | +0.01 | buy |
| K2 PRINCIPAL FUND, L.P. | 0 | 135,100 | +135,100 | 0.00 | 0.18 | +0.18 | buy |
| Walleye Capital LLC | 362,152 | 487,165 | +125,013 | 0.01 | 0.03 | +0.02 | buy |
| Y-Intercept (Hong Kong) Ltd | 44,978 | 168,090 | +123,112 | 0.00 | 0.05 | +0.04 | buy |
| Squarepoint Ops LLC | 16,293 | 138,671 | +122,378 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF MONTREAL /CAN/ | 0 | 119,222 | +119,222 | 0.00 | 0.00 | +0.00 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 0 | 115,839 | +115,839 | 0.00 | 0.00 | +0.00 | buy |
| LPL Financial LLC | 0 | 109,568 | +109,568 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 231,385 | 332,206 | +100,821 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 45,886 | 146,127 | +100,241 | 0.00 | 0.00 | +0.00 | buy |
| CreativeOne Wealth, LLC | 0 | 94,439 | +94,439 | 0.00 | 0.03 | +0.03 | buy |
| RTW INVESTMENTS, LP | 10,632,390 | 10,700,974 | +68,584 | 0.59 | 1.29 | +0.71 | buy |
| Dorsey Wright & Associates | 0 | 62,449 | +62,449 | 0.00 | 0.15 | +0.15 | buy |
| Campbell & CO Investment Adviser LLC | 0 | 61,816 | +61,816 | 0.00 | 0.05 | +0.05 | buy |
| ROYAL BANK OF CANADA | 244,526 | 299,808 | +55,282 | 0.00 | 0.00 | +0.00 | buy |
| CIBC WORLD MARKET INC. | 0 | 52,110 | +52,110 | 0.00 | 0.00 | +0.00 | buy |
| NATIONAL BANK OF CANADA /FI/ | 549 | 51,727 | +51,178 | 0.00 | 0.00 | +0.00 | buy |
| EXCHANGE TRADED CONCEPTS, LLC | 0 | 50,102 | +50,102 | 0.00 | 0.00 | +0.00 | buy |
| QRG CAPITAL MANAGEMENT, INC. | 0 | 48,657 | +48,657 | 0.00 | 0.01 | +0.01 | buy |
| MOUNT VERNON ASSOCIATES INC /MD/ | 0 | 38,000 | +38,000 | 0.00 | 0.35 | +0.35 | buy |
| Merit Financial Group, LLC | 0 | 37,847 | +37,847 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 0 | 37,585 | +37,585 | 0.00 | 0.00 | +0.00 | buy |
| Burns Matteson Capital Management, LLC | 0 | 32,861 | +32,861 | 0.00 | 0.15 | +0.15 | buy |
| Integrated Wealth Concepts LLC | 0 | 32,516 | +32,516 | 0.00 | 0.00 | +0.00 | buy |
| STIFEL FINANCIAL CORP | 29,000 | 60,469 | +31,469 | 0.00 | 0.00 | +0.00 | buy |
| TD Waterhouse Canada Inc. | 690 | 30,306 | +29,616 | 0.00 | 0.00 | +0.00 | buy |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | 147,590 | 175,373 | +27,783 | 0.06 | 0.16 | +0.10 | buy |
| Atria Investments, Inc | 0 | 27,732 | +27,732 | 0.00 | 0.00 | +0.00 | buy |
| Cetera Investment Advisers | 0 | 24,561 | +24,561 | 0.00 | 0.00 | +0.00 | buy |
| Jain Global LLC | 0 | 23,737 | +23,737 | 0.00 | 0.00 | +0.00 | buy |
| Rockefeller Capital Management L.P. | 1,276 | 23,644 | +22,368 | 0.00 | 0.00 | +0.00 | buy |
| Janney Montgomery Scott LLC | 0 | 21,196 | +21,196 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 371,697 | 391,587 | +19,890 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 0 | 19,054 | +19,054 | 0.00 | 0.00 | +0.00 | buy |
| Gladstone Institutional Advisory LLC | 16,944 | 35,589 | +18,645 | 0.00 | 0.02 | +0.01 | buy |
| PERSONAL CFO SOLUTIONS, LLC | 0 | 17,180 | +17,180 | 0.00 | 0.04 | +0.04 | buy |
| FOX RUN MANAGEMENT, L.L.C. | 13,058 | 30,208 | +17,150 | 0.01 | 0.07 | +0.06 | buy |
| Entropy Technologies, LP | 19,970 | 36,480 | +16,510 | 0.01 | 0.02 | +0.02 | buy |
| Caitong International Asset Management Co., Ltd | 169 | 15,578 | +15,409 | 0.00 | 0.03 | +0.03 | buy |
| RAYMOND JAMES FINANCIAL INC | 17,429 | 32,642 | +15,213 | 0.00 | 0.00 | +0.00 | buy |
| CHIRON CAPITAL MANAGEMENT, LLC | 0 | 15,086 | +15,086 | 0.00 | 0.19 | +0.19 | buy |
| Arax Advisory Partners | 240 | 15,240 | +15,000 | 0.00 | 0.00 | +0.00 | buy |
| OSAIC HOLDINGS, INC. | 0 | 14,113 | +14,113 | 0.00 | 0.00 | +0.00 | buy |
| IFG Advisory, LLC | 0 | 13,845 | +13,845 | 0.00 | 0.01 | +0.01 | buy |
| COMMONWEALTH EQUITY SERVICES, LLC | 0 | 12,972 | +12,972 | 0.00 | 0.00 | +0.00 | buy |
| SIG BROKERAGE, LP | 0 | 12,290 | +12,290 | 0.00 | 0.03 | +0.03 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 62,962 | 75,187 | +12,225 | 0.00 | 0.00 | +0.00 | buy |
| Scientech Research LLC | 13,037 | 24,846 | +11,809 | 0.06 | 0.28 | +0.22 | buy |
| EntryPoint Capital, LLC | 16,612 | 28,375 | +11,763 | 0.03 | 0.10 | +0.07 | buy |
| DCF Advisers, LLC | 42,500 | 54,250 | +11,750 | 0.09 | 0.20 | +0.11 | buy |
| Walleye Trading LLC | 0 | 11,498 | +11,498 | 0.00 | 0.00 | +0.00 | buy |
| HighTower Advisors, LLC | 30,641 | 40,727 | +10,086 | 0.00 | 0.00 | +0.00 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 0 | 9,667 | +9,667 | 0.00 | 0.00 | +0.00 | buy |
| MERCER GLOBAL ADVISORS INC /ADV | 0 | 9,450 | +9,450 | 0.00 | 0.00 | +0.00 | buy |
| MML INVESTORS SERVICES, LLC | 10,004 | 19,006 | +9,002 | 0.00 | 0.00 | +0.00 | buy |
| HighVista Strategies LLC | 364,360 | 371,120 | +6,760 | 0.56 | 1.20 | +0.64 | buy |
| BARCLAYS PLC | 3,863 | 9,108 | +5,245 | 0.00 | 0.00 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 236,380 | 240,874 | +4,494 | 0.00 | 0.00 | +0.00 | buy |
| China Universal Asset Management Co., Ltd. | 16,735 | 21,183 | +4,448 | 0.01 | 0.02 | +0.01 | buy |
| GSA CAPITAL PARTNERS LLP | 30,206 | 34,317 | +4,111 | 0.01 | 0.03 | +0.02 | buy |
| Persistent Asset Partners Ltd | 8,060 | 11,845 | +3,785 | 0.02 | 0.05 | +0.04 | buy |
| WINTON GROUP Ltd | 14,900 | 17,900 | +3,000 | 0.00 | 0.01 | +0.01 | buy |
| Quadrature Capital Ltd | 17,891 | 20,406 | +2,515 | 0.00 | 0.00 | +0.00 | buy |
| State of Wyoming | 0 | 2,318 | +2,318 | 0.00 | 0.00 | +0.00 | buy |
| MCDONALD PARTNERS LLC | 0 | 2,040 | +2,040 | 0.00 | 0.01 | +0.01 | buy |
| FLAGSHIP HARBOR ADVISORS, LLC | 42,599 | 44,599 | +2,000 | 0.01 | 0.02 | +0.01 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 2,192 | 4,159 | +1,967 | 0.00 | 0.00 | +0.00 | buy |
| Aquatic Capital Management LLC | 63,533 | 65,180 | +1,647 | 0.01 | 0.03 | +0.02 | buy |
| DT Investment Partners, LLC | 0 | 1,590 | +1,590 | 0.00 | 0.00 | +0.00 | buy |
| HOEY INVESTMENTS, INC | 0 | 1,500 | +1,500 | 0.00 | 0.00 | +0.00 | buy |
| JONES FINANCIAL COMPANIES LLLP | 0 | 1,450 | +1,450 | 0.00 | 0.00 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 4,919 | 5,953 | +1,034 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 2,019 | 3,040 | +1,021 | 0.00 | 0.00 | +0.00 | buy |
| Parallel Advisors, LLC | 7,268 | 8,183 | +915 | 0.00 | 0.00 | +0.00 | buy |
| Federation des caisses Desjardins du Quebec | 175 | 1,025 | +850 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 80,442 | 81,279 | +837 | 0.00 | 0.00 | +0.00 | buy |
| Dougherty Wealth Advisers LLC | 0 | 695 | +695 | 0.00 | 0.01 | +0.01 | buy |
| Quantbot Technologies LP | 0 | 596 | +596 | 0.00 | 0.00 | +0.00 | buy |