| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Deep Track Capital, LP | 0 | 8,859,648 | +8,859,648 | 0.00 | 0.82 | +0.82 | buy |
| RTW INVESTMENTS, LP | 3,098,987 | 5,538,168 | +2,439,181 | 0.18 | 0.24 | +0.07 | buy |
| Logos Global Management LP | 0 | 2,000,000 | +2,000,000 | 0.00 | 1.02 | +1.02 | buy |
| Nantahala Capital Management, LLC | 1,000,000 | 2,829,232 | +1,829,232 | 0.26 | 0.67 | +0.40 | buy |
| Vivo Capital, LLC | 1,608,000 | 3,362,385 | +1,754,385 | 0.68 | 1.27 | +0.59 | buy |
| Laurion Capital Management LP | 439,311 | 1,764,906 | +1,325,595 | 0.10 | 0.39 | +0.28 | buy |
| Woodline Partners LP | 461,929 | 1,754,856 | +1,292,927 | 0.01 | 0.03 | +0.02 | buy |
| UBS Group AG | 0 | 1,049,161 | +1,049,161 | 0.00 | 0.00 | +0.00 | buy |
| Blue Owl Capital Holdings LP | 161,238 | 1,135,828 | +974,590 | 0.14 | 1.05 | +0.91 | buy |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 0 | 701,754 | +701,754 | 0.00 | 0.02 | +0.02 | buy |
| 22NW, LP | 0 | 646,559 | +646,559 | 0.00 | 1.24 | +1.24 | buy |
| DAFNA Capital Management LLC | 243,210 | 711,046 | +467,836 | 0.23 | 0.58 | +0.34 | buy |
| TANG CAPITAL MANAGEMENT LLC | 1,000,000 | 1,400,000 | +400,000 | 0.25 | 0.22 | -0.03 | buy |
| GMT CAPITAL CORP | 1,547,800 | 1,781,718 | +233,918 | 0.29 | 0.27 | -0.01 | buy |
| Aisling Capital Management LP | 964,500 | 1,198,418 | +233,918 | 1.29 | 1.19 | -0.11 | buy |
| Polar Asset Management Partners Inc. | 0 | 229,806 | +229,806 | 0.00 | 0.02 | +0.02 | buy |
| Good Life Advisors, LLC | 0 | 180,000 | +180,000 | 0.00 | 0.04 | +0.04 | buy |
| ALLIANCEBERNSTEIN L.P. | 0 | 150,612 | +150,612 | 0.00 | 0.00 | +0.00 | buy |
| BIT Capital GmbH | 115,697 | 246,320 | +130,623 | 0.04 | 0.08 | +0.05 | buy |
| Rosalind Advisors, Inc. | 707,625 | 823,286 | +115,661 | 1.44 | 1.15 | -0.29 | buy |
| AdvisorShares Investments LLC | 66,602 | 140,541 | +73,939 | 0.05 | 0.08 | +0.03 | buy |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 0 | 73,227 | +73,227 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 169,479 | 240,591 | +71,112 | 0.00 | 0.00 | +0.00 | buy |
| ARK Investment Management LLC | 1,736,202 | 1,804,803 | +68,601 | 0.05 | 0.05 | -0.00 | buy |
| BlackRock, Inc. | 343,507 | 411,928 | +68,421 | 0.00 | 0.00 | -0.00 | buy |
| EntryPoint Capital, LLC | 65,519 | 117,651 | +52,132 | 0.10 | 0.15 | +0.05 | buy |
| SIMPLEX TRADING, LLC | 0 | 48,651 | +48,651 | 0.00 | 0.00 | +0.00 | buy |
| GROUP ONE TRADING LLC | 0 | 48,289 | +48,289 | 0.00 | 0.01 | +0.01 | buy |
| Virtus Investment Advisers, LLC | 0 | 37,225 | +37,225 | 0.00 | 0.03 | +0.03 | buy |
| Vident Advisory, LLC | 0 | 33,162 | +33,162 | 0.00 | 0.00 | +0.00 | buy |
| ROYAL BANK OF CANADA | 59,713 | 89,446 | +29,733 | 0.00 | 0.00 | +0.00 | buy |
| State of Tennessee, Department of Treasury | 0 | 29,719 | +29,719 | 0.00 | 0.00 | +0.00 | buy |
| VIRTUS ADVISERS, LLC | 16,121 | 41,695 | +25,574 | 0.02 | 0.08 | +0.05 | buy |
| OLD NATIONAL BANCORP /IN/ | 0 | 15,600 | +15,600 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 48,415 | 63,922 | +15,507 | 0.00 | 0.00 | -0.00 | buy |
| Bayesian Capital Management, LP | 0 | 15,100 | +15,100 | 0.00 | 0.01 | +0.01 | buy |
| LGT Financial Advisors LLC | 0 | 14,700 | +14,700 | 0.00 | 0.13 | +0.13 | buy |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | 0 | 14,273 | +14,273 | 0.00 | 0.00 | +0.00 | buy |
| Ethos Financial Group, LLC | 0 | 12,308 | +12,308 | 0.00 | 0.00 | +0.00 | buy |
| WOLVERINE TRADING, LLC | 0 | 11,675 | +11,675 | 0.00 | 0.00 | +0.00 | buy |
| ALPS ADVISORS INC | 55,332 | 66,231 | +10,899 | 0.00 | 0.00 | -0.00 | buy |
| Cerity Partners LLC | 0 | 10,287 | +10,287 | 0.00 | 0.00 | +0.00 | buy |
| GAMMA Investing LLC | 5,346 | 10,349 | +5,003 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 0 | 3,629 | +3,629 | 0.00 | 0.00 | +0.00 | buy |
| FLAGSHIP HARBOR ADVISORS, LLC | 11,312 | 14,446 | +3,134 | 0.00 | 0.00 | -0.00 | buy |
| Atom Investors LP | 17,515 | 20,212 | +2,697 | 0.01 | 0.01 | -0.00 | buy |
| Caitong International Asset Management Co., Ltd | 156 | 2,742 | +2,586 | 0.00 | 0.01 | +0.01 | buy |
| Conservest Capital Advisors, Inc. | 13,363 | 15,363 | +2,000 | 0.01 | 0.00 | -0.00 | buy |
| China Universal Asset Management Co., Ltd. | 10,782 | 12,455 | +1,673 | 0.00 | 0.00 | -0.00 | buy |
| BARCLAYS PLC | 419,194 | 420,825 | +1,631 | 0.00 | 0.00 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 2,403 | 3,445 | +1,042 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 0 | 906 | +906 | 0.00 | 0.00 | +0.00 | buy |
| Banque Transatlantique SA | 0 | 478 | +478 | 0.00 | 0.00 | +0.00 | buy |
| KENNEDY CAPITAL MANAGEMENT LLC | 33,976 | 34,415 | +439 | 0.00 | 0.00 | -0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 1,694 | 2,013 | +319 | 0.00 | 0.00 | -0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 682 | 933 | +251 | 0.00 | 0.00 | +0.00 | buy |
| GF FUND MANAGEMENT CO. LTD. | 1,068 | 1,261 | +193 | 0.00 | 0.00 | -0.00 | buy |
| Steward Partners Investment Advisory, LLC | 1,000 | 1,100 | +100 | 0.00 | 0.00 | -0.00 | buy |
| SBI Securities Co., Ltd. | 56 | 104 | +48 | 0.00 | 0.00 | +0.00 | buy |
| Larson Financial Group LLC | 100 | 112 | +12 | 0.00 | 0.00 | -0.00 | buy |
| MAI Capital Management | 800 | 800 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ADIRONDACK TRUST CO | 505 | 505 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SHELL ASSET MANAGEMENT CO | 130 | 130 | 0 | 0.00 | 0.00 | 0.00 | hold |
| GEODE CAPITAL MANAGEMENT, LLC | 42,169 | 42,169 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PRINCIPAL SECURITIES, INC. | 288 | 288 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CIBC Private Wealth Group LLC | 23 | 23 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Oasis Management Co Ltd. | 107,911 | 107,911 | 0 | 0.13 | 0.10 | -0.03 | hold |
| North Star Investment Management Corp. | 3,372 | 3,372 | 0 | 0.00 | 0.00 | -0.00 | hold |
| GHP Investment Advisors, Inc. | 250 | 250 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PFM Health Sciences, LP | 451,267 | 451,267 | 0 | 0.13 | 0.10 | -0.03 | hold |
| Ancora Advisors LLC | 1,330 | 1,330 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SIGNATUREFD, LLC | 1 | 1 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Saba Capital Management, L.P. | 151,033 | 151,033 | 0 | 0.01 | 0.01 | -0.00 | hold |
| CWM, LLC | 10,855 | 10,855 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Westside Investment Management, Inc. | 500 | 500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BOOTHBAY FUND MANAGEMENT, LLC | 62,300 | 62,300 | 0 | 0.01 | 0.01 | -0.00 | hold |
| Colonial Trust Advisors | 2,000 | 2,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Anfield Capital Management, LLC | 35 | 35 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Tradewinds Capital Management, LLC | 14 | 14 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SVB WEALTH LLC | 26,607 | 26,607 | 0 | 0.00 | 0.00 | +0.00 | hold |
| NewEdge Advisors, LLC | 550 | 550 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Anchor Investment Management, LLC | 550 | 550 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TruNorth Capital Management, LLC | 60 | 60 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Brown University | 214,200 | 214,200 | 0 | 0.35 | 0.28 | -0.06 | hold |
| Intellectus Partners, LLC | 10,100 | 10,100 | 0 | 0.01 | 0.01 | -0.00 | hold |
| Parallel Advisors, LLC | 134 | 134 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NVWM, LLC | 202 | 202 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Fore Capital, LLC | 35,000 | 35,000 | 0 | 0.16 | 0.12 | -0.04 | hold |
| Crewe Advisors LLC | 1,945 | 1,945 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Pacifica Partners Inc. | 420 | 420 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TSFG, LLC | 100 | 100 | 0 | 0.00 | 0.00 | 0.00 | hold |
| TFC Financial Management, Inc. | 52 | 52 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TCG Crossover Management, LLC | 3,858,000 | 3,858,000 | 0 | 1.43 | 1.51 | +0.08 | hold |
| Founders Fund VII Management, LLC | 278,880 | 278,880 | 0 | 100.00 | 100.00 | 0.00 | hold |
| Blue Trust, Inc. | 2,799 | 2,799 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Missouri Trust & Investment Co | 30 | 30 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TD Waterhouse Canada Inc. | 1,770 | 1,770 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Pathstone Holdings, LLC | 13,789 | 13,789 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Federation des caisses Desjardins du Quebec | 475 | 475 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CROWLEY WEALTH MANAGEMENT, INC. | 30 | 30 | 0 | 0.00 | 0.00 | -0.00 | hold |