| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| STATE STREET CORP | 1,891,465 | 3,853,951 | +1,962,486 | 0.00 | 0.00 | +0.00 | buy |
| TCG Crossover Management, LLC | 0 | 1,789,617 | +1,789,617 | 0.00 | 0.82 | +0.82 | buy |
| Prosight Management, LP | 865,350 | 2,392,523 | +1,527,173 | 5.08 | 6.82 | +1.74 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 701,604 | 1,610,186 | +908,582 | 0.00 | 0.00 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 885,551 | +885,551 | 0.00 | 0.02 | +0.02 | buy |
| Alyeska Investment Group, L.P. | 424,845 | 1,301,089 | +876,244 | 0.03 | 0.05 | +0.02 | buy |
| JANUS HENDERSON GROUP PLC | 4,701,112 | 5,350,453 | +649,341 | 0.05 | 0.03 | -0.02 | buy |
| VANGUARD GROUP INC | 2,417,104 | 2,906,386 | +489,282 | 0.00 | 0.00 | -0.00 | buy |
| JANE STREET GROUP, LLC | 81,322 | 540,233 | +458,911 | 0.00 | 0.01 | +0.01 | buy |
| GOLDMAN SACHS GROUP INC | 655,108 | 1,073,656 | +418,548 | 0.00 | 0.00 | -0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 103,476 | 471,009 | +367,533 | 0.00 | 0.01 | +0.01 | buy |
| University of Wisconsin Foundation | 0 | 362,000 | +362,000 | 0.00 | 4.20 | +4.20 | buy |
| BlackRock, Inc. | 3,730,994 | 4,080,200 | +349,206 | 0.00 | 0.00 | -0.00 | buy |
| Squarepoint Ops LLC | 66,161 | 390,952 | +324,791 | 0.00 | 0.01 | +0.01 | buy |
| CITADEL ADVISORS LLC | 802,784 | 1,104,144 | +301,360 | 0.02 | 0.01 | -0.01 | buy |
| Walleye Capital LLC | 35,821 | 323,017 | +287,196 | 0.01 | 0.03 | +0.02 | buy |
| BANK OF AMERICA CORP /DE/ | 493,452 | 738,330 | +244,878 | 0.00 | 0.00 | -0.00 | buy |
| UBS Group AG | 390,357 | 590,060 | +199,703 | 0.00 | 0.00 | -0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 100,645 | 289,808 | +189,163 | 0.00 | 0.00 | +0.00 | buy |
| ORBIMED ADVISORS LLC | 1,766,100 | 1,954,426 | +188,326 | 1.04 | 0.55 | -0.48 | buy |
| Caption Management, LLC | 90,000 | 272,500 | +182,500 | 0.13 | 0.17 | +0.04 | buy |
| ExodusPoint Capital Management, LP | 0 | 161,548 | +161,548 | 0.00 | 0.02 | +0.02 | buy |
| XTX Topco Ltd | 0 | 161,427 | +161,427 | 0.00 | 0.06 | +0.06 | buy |
| Trexquant Investment LP | 13,217 | 170,484 | +157,267 | 0.00 | 0.02 | +0.02 | buy |
| Rock Springs Capital Management LP | 210,366 | 358,798 | +148,432 | 0.30 | 0.25 | -0.05 | buy |
| Rhenman & Partners Asset Management AB | 100,127 | 225,377 | +125,250 | 0.27 | 0.29 | +0.02 | buy |
| MORGAN STANLEY | 495,635 | 618,385 | +122,750 | 0.00 | 0.00 | -0.00 | buy |
| Qube Research & Technologies Ltd | 110,849 | 216,005 | +105,156 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 0 | 104,100 | +104,100 | 0.00 | 0.00 | +0.00 | buy |
| Blue Owl Capital Holdings LP | 0 | 100,000 | +100,000 | 0.00 | 0.43 | +0.43 | buy |
| Rafferty Asset Management, LLC | 76,196 | 175,248 | +99,052 | 0.01 | 0.01 | +0.00 | buy |
| ALGERT GLOBAL LLC | 88,217 | 183,367 | +95,150 | 0.04 | 0.04 | +0.00 | buy |
| Deep Track Capital, LP | 0 | 89,589 | +89,589 | 0.00 | 0.03 | +0.03 | buy |
| BARCLAYS PLC | 144,024 | 221,233 | +77,209 | 0.00 | 0.00 | -0.00 | buy |
| SPHERA FUNDS MANAGEMENT LTD. | 85,840 | 157,840 | +72,000 | 0.50 | 0.46 | -0.04 | buy |
| Logos Global Management LP | 935,000 | 1,000,000 | +65,000 | 2.26 | 0.92 | -1.34 | buy |
| Man Group plc | 0 | 64,512 | +64,512 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 63,544 | +63,544 | 0.00 | 0.00 | +0.00 | buy |
| Hudson Bay Capital Management LP | 50,000 | 110,000 | +60,000 | 0.01 | 0.01 | +0.00 | buy |
| TWINBEECH CAPITAL LP | 0 | 58,810 | +58,810 | 0.00 | 0.06 | +0.06 | buy |
| Headlands Technologies LLC | 0 | 56,497 | +56,497 | 0.00 | 0.07 | +0.07 | buy |
| Aquatic Capital Management LLC | 0 | 52,421 | +52,421 | 0.00 | 0.02 | +0.02 | buy |
| SG Americas Securities, LLC | 29,015 | 79,817 | +50,802 | 0.00 | 0.00 | -0.00 | buy |
| PROFUND ADVISORS LLC | 16,438 | 64,022 | +47,584 | 0.01 | 0.03 | +0.01 | buy |
| Schonfeld Strategic Advisors LLC | 0 | 45,453 | +45,453 | 0.00 | 0.00 | +0.00 | buy |
| Freestone Grove Partners LP | 0 | 41,806 | +41,806 | 0.00 | 0.00 | +0.00 | buy |
| TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY | 0 | 38,875 | +38,875 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 354,544 | 390,506 | +35,962 | 0.00 | 0.00 | -0.00 | buy |
| D. E. Shaw & Co., Inc. | 0 | 32,707 | +32,707 | 0.00 | 0.00 | +0.00 | buy |
| WINTON GROUP Ltd | 0 | 31,800 | +31,800 | 0.00 | 0.02 | +0.02 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,083,864 | 1,113,582 | +29,718 | 0.00 | 0.00 | -0.00 | buy |
| Atom Investors LP | 0 | 27,942 | +27,942 | 0.00 | 0.03 | +0.03 | buy |
| Rangeley Capital, LLC | 0 | 25,414 | +25,414 | 0.00 | 0.30 | +0.30 | buy |
| Quantinno Capital Management LP | 0 | 24,218 | +24,218 | 0.00 | 0.00 | +0.00 | buy |
| Raiffeisen Bank International AG | 24,000 | 46,000 | +22,000 | 0.01 | 0.01 | +0.00 | buy |
| Stonepine Capital Management, LLC | 0 | 20,000 | +20,000 | 0.00 | 0.22 | +0.22 | buy |
| CAPSTONE INVESTMENT ADVISORS, LLC | 0 | 19,508 | +19,508 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 28,518 | 47,919 | +19,401 | 0.00 | 0.00 | -0.00 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 0 | 19,334 | +19,334 | 0.00 | 0.02 | +0.02 | buy |
| Lion Point Capital, LP | 0 | 19,000 | +19,000 | 0.00 | 1.36 | +1.36 | buy |
| CITIGROUP INC | 5,515 | 24,218 | +18,703 | 0.00 | 0.00 | +0.00 | buy |
| Entropy Technologies, LP | 0 | 16,108 | +16,108 | 0.00 | 0.01 | +0.01 | buy |
| Quantbot Technologies LP | 0 | 15,348 | +15,348 | 0.00 | 0.01 | +0.01 | buy |
| Brevan Howard Capital Management LP | 0 | 14,757 | +14,757 | 0.00 | 0.00 | +0.00 | buy |
| SIMPLEX TRADING, LLC | 3,596 | 17,567 | +13,971 | 0.00 | 0.01 | +0.00 | buy |
| Aristides Capital LLC | 0 | 13,100 | +13,100 | 0.00 | 0.06 | +0.06 | buy |
| Virtus Investment Advisers, LLC | 4,452 | 17,388 | +12,936 | 0.03 | 0.07 | +0.03 | buy |
| FEDERATED HERMES, INC. | 0 | 11,898 | +11,898 | 0.00 | 0.00 | +0.00 | buy |
| MARTINGALE ASSET MANAGEMENT L P | 0 | 11,240 | +11,240 | 0.00 | 0.00 | +0.00 | buy |
| DARK FOREST CAPITAL MANAGEMENT LP | 46,856 | 57,363 | +10,507 | 0.03 | 0.04 | +0.01 | buy |
| Walleye Trading LLC | 0 | 10,447 | +10,447 | 0.00 | 0.00 | +0.00 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 0 | 9,956 | +9,956 | 0.00 | 0.00 | +0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 66,325 | 75,498 | +9,173 | 0.00 | 0.00 | -0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 18,953 | 27,691 | +8,738 | 0.00 | 0.00 | -0.00 | buy |
| OXFORD ASSET MANAGEMENT LLP | 14,206 | 22,811 | +8,605 | 0.11 | 0.11 | -0.00 | buy |
| DnB Asset Management AS | 8,919 | 17,274 | +8,355 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 22,364 | 30,148 | +7,784 | 0.00 | 0.00 | -0.00 | buy |
| Quadrature Capital Ltd | 26,861 | 33,002 | +6,141 | 0.01 | 0.00 | -0.00 | buy |
| Legal & General Group Plc | 37,916 | 43,467 | +5,551 | 0.00 | 0.00 | -0.00 | buy |
| AlphaQuest LLC | 7,320 | 12,855 | +5,535 | 0.01 | 0.01 | -0.00 | buy |
| FNY Investment Advisers, LLC | 5,210 | 10,300 | +5,090 | 0.04 | 0.04 | -0.00 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 33,520 | 38,487 | +4,967 | 0.00 | 0.00 | -0.00 | buy |
| Engineers Gate Manager LP | 8,916 | 13,147 | +4,231 | 0.00 | 0.00 | -0.00 | buy |
| JONES FINANCIAL COMPANIES LLLP | 88 | 4,226 | +4,138 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 24,469 | 28,322 | +3,853 | 0.00 | 0.00 | -0.00 | buy |
| Handelsbanken Fonder AB | 14,000 | 17,800 | +3,800 | 0.00 | 0.00 | -0.00 | buy |
| Caitong International Asset Management Co., Ltd | 0 | 3,713 | +3,713 | 0.00 | 0.01 | +0.01 | buy |
| Russell Investments Group, Ltd. | 17,502 | 21,062 | +3,560 | 0.00 | 0.00 | -0.00 | buy |
| Swiss National Bank | 74,600 | 77,100 | +2,500 | 0.00 | 0.00 | -0.00 | buy |
| ProShare Advisors LLC | 8,874 | 10,495 | +1,621 | 0.00 | 0.00 | -0.00 | buy |
| Bank of New York Mellon Corp | 120,472 | 122,066 | +1,594 | 0.00 | 0.00 | -0.00 | buy |
| CONGRESS ASSET MANAGEMENT CO | 55,773 | 57,342 | +1,569 | 0.01 | 0.01 | -0.00 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 4,863 | 5,953 | +1,090 | 0.00 | 0.00 | -0.00 | buy |
| SageView Advisory Group, LLC | 0 | 950 | +950 | 0.00 | 0.00 | +0.00 | buy |
| Nuveen, LLC | 95,629 | 96,416 | +787 | 0.00 | 0.00 | -0.00 | buy |
| Smartleaf Asset Management LLC | 0 | 692 | +692 | 0.00 | 0.00 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 2,323 | 2,923 | +600 | 0.00 | 0.00 | -0.00 | buy |
| SIGNATUREFD, LLC | 0 | 360 | +360 | 0.00 | 0.00 | +0.00 | buy |
| Aster Capital Management (DIFC) Ltd | 0 | 314 | +314 | 0.00 | 0.00 | +0.00 | buy |
| Woodline Partners LP | 1,026,938 | 1,027,221 | +283 | 0.12 | 0.05 | -0.06 | buy |