| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Corvex Management LP | 3,228,149 | 4,784,570 | +1,556,421 | 8.24 | 10.21 | +1.96 | buy |
| Casdin Capital, LLC | 3,007,164 | 3,707,164 | +700,000 | 14.62 | 12.74 | -1.88 | buy |
| LMR Partners LLP | 2,135,439 | 2,135,439 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BlackRock, Inc. | 1,550,708 | 1,706,239 | +155,531 | 0.00 | 0.00 | -0.00 | buy |
| GOLDMAN SACHS GROUP INC | 1,334,980 | 1,669,441 | +334,461 | 0.01 | 0.01 | +0.00 | buy |
| ARK Investment Management LLC | 1,324,583 | 1,610,189 | +285,606 | 0.66 | 0.72 | +0.06 | buy |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 775,269 | 1,400,653 | +625,384 | 0.16 | 0.29 | +0.12 | buy |
| MORGAN STANLEY | 532,235 | 988,297 | +456,062 | 0.00 | 0.00 | +0.00 | buy |
| CITADEL ADVISORS LLC | 647,401 | 865,462 | +218,061 | 0.03 | 0.03 | +0.00 | buy |
| First Light Asset Management, LLC | 242,927 | 783,923 | +540,996 | 1.40 | 3.27 | +1.87 | buy |
| Deep Track Capital, LP | 0 | 700,000 | +700,000 | 0.00 | 0.71 | +0.71 | buy |
| Sumitomo Mitsui Trust Group, Inc. | 633,457 | 666,581 | +33,124 | 0.03 | 0.03 | -0.00 | buy |
| Nikko Asset Management Americas, Inc. | 638,800 | 666,581 | +27,781 | 0.58 | 0.59 | +0.01 | buy |
| Zweig-DiMenna Associates LLC | 689,290 | 571,950 | -117,340 | 6.21 | 3.56 | -2.65 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 549,147 | 552,125 | +2,978 | 0.00 | 0.00 | -0.00 | buy |
| STATE STREET CORP | 472,445 | 527,815 | +55,370 | 0.00 | 0.00 | +0.00 | buy |
| GAGNON SECURITIES LLC | 303,149 | 524,865 | +221,716 | 4.49 | 6.94 | +2.45 | buy |
| D. E. Shaw & Co., Inc. | 467,197 | 467,197 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Aberdeen Group plc | 230,096 | 457,201 | +227,105 | 0.02 | 0.04 | +0.02 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 341,005 | 347,927 | +6,922 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 234,606 | 346,211 | +111,605 | 0.00 | 0.00 | +0.00 | buy |
| Assenagon Asset Management S.A. | 95,128 | 303,433 | +208,305 | 0.01 | 0.03 | +0.02 | buy |
| FRANKLIN RESOURCES INC | 607,221 | 280,938 | -326,283 | 0.01 | 0.00 | -0.01 | sell |
| DIMENSIONAL FUND ADVISORS LP | 265,791 | 280,619 | +14,828 | 0.00 | 0.00 | -0.00 | buy |
| NORGES BANK | 0 | 273,100 | +273,100 | 0.00 | 0.00 | +0.00 | buy |
| EVENTIDE ASSET MANAGEMENT, LLC | 459,015 | 269,542 | -189,473 | 0.49 | 0.25 | -0.24 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 243,780 | 243,780 | 0 | 0.00 | 0.00 | -0.00 | hold |
| UBS Group AG | 50,825 | 208,663 | +157,838 | 0.00 | 0.00 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 195,889 | 207,664 | +11,775 | 0.00 | 0.00 | -0.00 | buy |
| JANE STREET GROUP, LLC | 0 | 204,592 | +204,592 | 0.00 | 0.01 | +0.01 | buy |
| ASHFORD CAPITAL MANAGEMENT INC | 174,512 | 201,986 | +27,474 | 1.38 | 1.49 | +0.10 | buy |
| Portolan Capital Management, LLC | 102,575 | 200,315 | +97,740 | 0.35 | 0.51 | +0.16 | buy |
| Alamea Verwaltungs GmbH | 185,989 | 185,989 | 0 | 8.85 | 10.20 | +1.35 | hold |
| NORTHERN TRUST CORP | 175,767 | 183,841 | +8,074 | 0.00 | 0.00 | -0.00 | buy |
| Sixth Street Partners Management Company, L.P. | 0 | 177,937 | +177,937 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 170,615 | 177,937 | +7,322 | 0.00 | 0.00 | -0.00 | buy |
| Gagnon Advisors, LLC | 148,225 | 177,870 | +29,645 | 7.00 | 7.76 | +0.76 | buy |
| MILLENNIUM MANAGEMENT LLC | 149,906 | 155,575 | +5,669 | 0.01 | 0.01 | +0.00 | buy |
| Rockefeller Capital Management L.P. | 96,590 | 151,164 | +54,574 | 0.01 | 0.02 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 70,105 | 142,315 | +72,210 | 0.01 | 0.01 | +0.00 | buy |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 0 | 141,500 | +141,500 | 0.00 | 0.01 | +0.01 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 7,718 | 123,690 | +115,972 | 0.00 | 0.00 | +0.00 | buy |
| RAYMOND JAMES FINANCIAL INC | 610,073 | 123,418 | -486,655 | 0.01 | 0.00 | -0.01 | sell |
| SILVERARC CAPITAL MANAGEMENT, LLC | 0 | 122,269 | +122,269 | 0.00 | 0.93 | +0.93 | buy |
| ROYCE & ASSOCIATES LP | 140,513 | 112,136 | -28,377 | 0.09 | 0.06 | -0.03 | sell |
| Q Global Advisors, LLC | 111,701 | 111,701 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TUDOR INVESTMENT CORP ET AL | 33,540 | 108,839 | +75,299 | 0.01 | 0.03 | +0.02 | buy |
| FRED ALGER MANAGEMENT, LLC | 202,771 | 108,527 | -94,244 | 0.06 | 0.02 | -0.03 | sell |
| Science & Technology Partners, L.P. | 241,200 | 106,387 | -134,813 | 4.06 | 1.23 | -2.83 | sell |
| TORONTO DOMINION BANK | 105,950 | 105,050 | -900 | 0.00 | 0.00 | -0.00 | sell |
| THRIVENT FINANCIAL FOR LUTHERANS | 153,721 | 101,992 | -51,729 | 0.02 | 0.01 | -0.01 | sell |
| Point72 Asset Management, L.P. | 75,795 | 97,300 | +21,505 | 0.01 | 0.01 | +0.00 | buy |
| BARCLAYS PLC | 7,864 | 97,234 | +89,370 | 0.00 | 0.00 | +0.00 | buy |
| StoneX Group Inc. | 32,396 | 97,188 | +64,792 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 92,424 | +92,424 | 0.00 | 0.01 | +0.01 | buy |
| TORONTO DOMINION BANK | 0 | 88,158 | +88,158 | 0.00 | 0.01 | +0.01 | buy |
| Prosight Management, LP | 523,463 | 85,500 | -437,963 | 5.51 | 1.01 | -4.50 | sell |
| Pentwater Capital Management LP | 0 | 82,500 | +82,500 | 0.00 | 0.05 | +0.05 | buy |
| BNP Paribas Asset Management Holding S.A. | 77,369 | 77,305 | -64 | 0.01 | 0.01 | -0.00 | sell |
| ARDSLEY ADVISORY PARTNERS LP | 100,000 | 75,000 | -25,000 | 0.98 | 0.56 | -0.42 | sell |
| Virtu Financial LLC | 0 | 73,345 | +73,345 | 0.00 | 0.00 | 0.00 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 102,929 | 69,169 | -33,760 | 0.00 | 0.00 | -0.00 | sell |
| Walleye Capital LLC | 0 | 67,900 | +67,900 | 0.00 | 0.02 | +0.02 | buy |
| Legal Advantage Investments, Inc. | 61,675 | 67,045 | +5,370 | 2.05 | 1.61 | -0.43 | buy |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | 57,759 | 66,216 | +8,457 | 0.28 | 0.29 | +0.01 | buy |
| Bank of New York Mellon Corp | 315,508 | 62,028 | -253,480 | 0.00 | 0.00 | -0.00 | sell |
| WOLVERINE ASSET MANAGEMENT LLC | 58,876 | 60,320 | +1,444 | 0.00 | 0.00 | -0.00 | buy |
| JPMORGAN CHASE & CO | 33,674 | 54,387 | +20,713 | 0.00 | 0.00 | +0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 249,432 | 54,336 | -195,096 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 3,137 | 53,894 | +50,757 | 0.00 | 0.00 | +0.00 | buy |
| Quantinno Capital Management LP | 3,810 | 53,454 | +49,644 | 0.00 | 0.00 | +0.00 | buy |
| Jefferies Financial Group Inc. | 0 | 49,800 | +49,800 | 0.00 | 0.03 | +0.03 | buy |
| Meridiem Capital Partners LP | 55,585 | 46,764 | -8,821 | 0.23 | 0.15 | -0.09 | sell |
| NIA IMPACT ADVISORS, LLC | 31,631 | 46,731 | +15,100 | 0.90 | 1.33 | +0.43 | buy |
| Nuveen, LLC | 41,944 | 46,158 | +4,214 | 0.00 | 0.00 | +0.00 | buy |
| Corient Private Wealth LLC | 0 | 44,658 | +44,658 | 0.00 | 0.00 | +0.00 | buy |
| Kovack Advisors, Inc. | 33,960 | 43,092 | +9,132 | 0.12 | 0.14 | +0.03 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 46,377 | 43,041 | -3,336 | 0.00 | 0.00 | -0.00 | sell |
| Slow Capital, Inc. | 40,457 | 42,500 | +2,043 | 0.34 | 0.34 | +0.00 | buy |
| Swiss National Bank | 40,000 | 40,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| D. E. Shaw & Co., Inc. | 18,903 | 38,877 | +19,974 | 0.00 | 0.00 | +0.00 | buy |
| RBF Capital, LLC | 37,340 | 37,340 | 0 | 0.12 | 0.11 | -0.01 | hold |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 25,804 | 36,939 | +11,135 | 0.00 | 0.00 | +0.00 | buy |
| TD ASSET MANAGEMENT INC | 34,884 | 34,884 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Longaeva Partners L.P. | 0 | 34,863 | +34,863 | 0.00 | 0.07 | +0.07 | buy |
| One Capital Management, LLC | 33,306 | 33,306 | 0 | 0.06 | 0.06 | +0.00 | hold |
| FORA Capital, LLC | 0 | 33,225 | +33,225 | 0.00 | 0.16 | +0.16 | buy |
| LAZARD ASSET MANAGEMENT LLC | 33,894 | 32,852 | -1,042 | 0.00 | 0.00 | -0.00 | sell |
| Vestmark Advisory Solutions, Inc. | 28,865 | 32,091 | +3,226 | 0.02 | 0.02 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 18,390 | 29,172 | +10,782 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 30,300 | 29,138 | -1,162 | 0.00 | 0.00 | -0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 23,026 | 28,891 | +5,865 | 0.00 | 0.00 | +0.00 | buy |
| Brevan Howard Capital Management LP | 5,666 | 28,172 | +22,506 | 0.00 | 0.03 | +0.02 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 27,521 | +27,521 | 0.00 | 0.04 | +0.04 | buy |
| RHUMBLINE ADVISERS | 23,520 | 25,183 | +1,663 | 0.00 | 0.00 | +0.00 | buy |
| ExodusPoint Capital Management, LP | 0 | 25,174 | +25,174 | 0.00 | 0.02 | +0.02 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 25,045 | 21,935 | -3,110 | 0.00 | 0.00 | -0.00 | sell |
| ALGERT GLOBAL LLC | 12,192 | 21,932 | +9,740 | 0.01 | 0.02 | +0.01 | buy |
| DEUTSCHE BANK AG\ | 17,618 | 21,880 | +4,262 | 0.00 | 0.00 | +0.00 | buy |
| Quadrature Capital Ltd | 0 | 20,422 | +20,422 | 0.00 | 0.01 | +0.01 | buy |