| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Casdin Capital, LLC | 3,507,164 | 3,507,164 | 0 | 9.92 | 18.03 | +8.10 | hold |
| Corvex Management LP | 2,473,781 | 2,473,781 | 0 | 4.30 | 6.92 | +2.62 | hold |
| LMR Partners LLP | 0 | 1,532,805 | +1,532,805 | 0.00 | 0.00 | +0.00 | buy |
| BlackRock, Inc. | 1,066,202 | 1,179,812 | +113,610 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 1,048,644 | 1,143,491 | +94,847 | 0.01 | 0.02 | +0.01 | buy |
| ORACLE INVESTMENT MANAGEMENT INC | 1,045,768 | 1,023,468 | -22,300 | 35.47 | 52.82 | +17.34 | sell |
| VANGUARD GROUP INC | 849,442 | 1,006,210 | +156,768 | 0.00 | 0.00 | +0.00 | buy |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC | 172,945 | 755,564 | +582,619 | 0.33 | 1.94 | +1.61 | buy |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 0 | 669,995 | +669,995 | 0.00 | 0.13 | +0.13 | buy |
| LORD, ABBETT & CO. LLC | 0 | 630,473 | +630,473 | 0.00 | 0.15 | +0.15 | buy |
| FRED ALGER MANAGEMENT, LLC | 394,230 | 546,054 | +151,824 | 0.08 | 0.20 | +0.12 | buy |
| D. E. Shaw & Co., Inc. | 467,197 | 467,197 | 0 | 0.00 | 0.00 | +0.00 | hold |
| FMR LLC | 53,825 | 402,494 | +348,669 | 0.00 | 0.00 | +0.00 | buy |
| MACQUARIE GROUP LTD | 0 | 384,480 | +384,480 | 0.00 | 0.04 | +0.04 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 377,631 | 382,350 | +4,719 | 0.00 | 0.00 | +0.00 | buy |
| GAGNON SECURITIES LLC | 541,943 | 359,376 | -182,567 | 4.56 | 5.57 | +1.01 | sell |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 472,783 | 324,918 | -147,865 | 0.17 | 0.21 | +0.03 | sell |
| STATE STREET CORP | 314,914 | 319,908 | +4,994 | 0.00 | 0.00 | +0.00 | buy |
| NEXT CENTURY GROWTH INVESTORS LLC | 141,113 | 312,014 | +170,901 | 0.49 | 1.80 | +1.31 | buy |
| Zweig-DiMenna Associates LLC | 0 | 309,500 | +309,500 | 0.00 | 2.01 | +2.01 | buy |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 177,500 | 300,600 | +123,100 | 0.02 | 0.05 | +0.03 | buy |
| D. E. Shaw & Co., Inc. | 31,391 | 294,517 | +263,126 | 0.00 | 0.02 | +0.02 | buy |
| Divisadero Street Capital Management, LP | 221,944 | 288,240 | +66,296 | 1.21 | 2.77 | +1.56 | buy |
| Assenagon Asset Management S.A. | 329,256 | 267,614 | -61,642 | 0.03 | 0.04 | +0.01 | sell |
| Invesco Ltd. | 5,697 | 255,351 | +249,654 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 250,930 | 250,930 | 0 | 0.00 | 0.00 | +0.00 | hold |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 224,382 | 221,097 | -3,285 | 0.03 | 0.06 | +0.03 | sell |
| MORGAN STANLEY | 198,353 | 212,832 | +14,479 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 93,573 | 205,116 | +111,543 | 0.01 | 0.02 | +0.02 | buy |
| FARALLON CAPITAL MANAGEMENT LLC | 0 | 195,000 | +195,000 | 0.00 | 0.08 | +0.08 | buy |
| Gagnon Advisors, LLC | 255,059 | 187,618 | -67,441 | 6.99 | 9.23 | +2.24 | sell |
| NORTHERN TRUST CORP | 150,043 | 179,651 | +29,608 | 0.00 | 0.00 | +0.00 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 60,005 | 166,094 | +106,089 | 0.01 | 0.06 | +0.05 | buy |
| TWO SIGMA INVESTMENTS, LP | 40,416 | 152,073 | +111,657 | 0.00 | 0.03 | +0.02 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 147,034 | 151,403 | +4,369 | 0.00 | 0.00 | +0.00 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 0 | 140,792 | +140,792 | 0.00 | 0.00 | +0.00 | buy |
| Tri Locum Partners LP | 0 | 127,567 | +127,567 | 0.00 | 2.03 | +2.03 | buy |
| OBERWEIS ASSET MANAGEMENT INC/ | 122,000 | 123,500 | +1,500 | 0.27 | 0.45 | +0.18 | buy |
| BOSUN ASSET MANAGEMENT, LLC | 170,134 | 117,274 | -52,860 | 3.48 | 4.05 | +0.57 | sell |
| Q Global Advisors, LLC | 115,474 | 111,701 | -3,773 | 0.01 | 0.02 | +0.01 | sell |
| JPMORGAN CHASE & CO | 52,161 | 107,891 | +55,730 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 180,398 | 105,413 | -74,985 | 0.01 | 0.01 | +0.00 | sell |
| PRUDENTIAL FINANCIAL INC | 0 | 103,275 | +103,275 | 0.00 | 0.01 | +0.01 | buy |
| TUDOR INVESTMENT CORP ET AL | 60,726 | 101,810 | +41,084 | 0.03 | 0.08 | +0.05 | buy |
| Nicholas Investment Partners, LP | 69,337 | 97,049 | +27,712 | 0.27 | 0.66 | +0.39 | buy |
| EMERALD ADVISERS, LLC | 0 | 91,818 | +91,818 | 0.00 | 0.27 | +0.27 | buy |
| Allspring Global Investments Holdings, LLC | 177 | 90,151 | +89,974 | 0.00 | 0.01 | +0.01 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 38,000 | 88,000 | +50,000 | 0.00 | 0.01 | +0.00 | buy |
| Palisades Investment Partners, LLC | 0 | 83,604 | +83,604 | 0.00 | 2.71 | +2.71 | buy |
| BARCLAYS PLC | 18,921 | 80,407 | +61,486 | 0.00 | 0.00 | +0.00 | buy |
| CITADEL ADVISORS LLC | 29,805 | 79,090 | +49,285 | 0.00 | 0.01 | +0.00 | buy |
| Trexquant Investment LP | 122,012 | 74,912 | -47,100 | 0.07 | 0.07 | +0.00 | sell |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | 0 | 71,709 | +71,709 | 0.00 | 0.04 | +0.04 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 15,229 | 68,072 | +52,843 | 0.00 | 0.01 | +0.01 | buy |
| NORGES BANK | 0 | 68,000 | +68,000 | 0.00 | 0.00 | +0.00 | buy |
| Lisanti Capital Growth, LLC | 36,615 | 67,900 | +31,285 | 0.39 | 1.26 | +0.86 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 63,578 | 66,968 | +3,390 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asset Management, L.P. | 293,671 | 63,088 | -230,583 | 0.04 | 0.01 | -0.03 | sell |
| CASTLEARK MANAGEMENT LLC | 0 | 61,710 | +61,710 | 0.00 | 0.17 | +0.17 | buy |
| Calamos Advisors LLC | 85,002 | 59,527 | -25,475 | 0.02 | 0.02 | +0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 574,436 | 58,803 | -515,633 | 0.02 | 0.00 | -0.02 | sell |
| EMERALD MUTUAL FUND ADVISERS TRUST | 0 | 57,637 | +57,637 | 0.00 | 0.27 | +0.27 | buy |
| AQR CAPITAL MANAGEMENT LLC | 87,390 | 57,531 | -29,859 | 0.01 | 0.01 | +0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 0 | 56,588 | +56,588 | 0.00 | 0.00 | +0.00 | buy |
| WOLVERINE ASSET MANAGEMENT LLC | 46,545 | 51,537 | +4,992 | 0.00 | 0.00 | +0.00 | buy |
| Informed Momentum Co LLC | 32,737 | 51,183 | +18,446 | 0.21 | 0.56 | +0.35 | buy |
| NISA INVESTMENT ADVISORS, LLC | 34 | 50,043 | +50,009 | 0.00 | 0.01 | +0.01 | buy |
| UBS Group AG | 13,416 | 46,905 | +33,489 | 0.00 | 0.00 | +0.00 | buy |
| NATIONAL BANK OF CANADA /FI/ | 0 | 45,000 | +45,000 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 0 | 43,242 | +43,242 | 0.00 | 0.01 | +0.01 | buy |
| ALGERT GLOBAL LLC | 66,128 | 42,926 | -23,202 | 0.08 | 0.08 | +0.00 | sell |
| Bank of New York Mellon Corp | 32,317 | 40,914 | +8,597 | 0.00 | 0.00 | +0.00 | buy |
| RBF Capital, LLC | 37,340 | 37,340 | 0 | 0.08 | 0.15 | +0.07 | hold |
| LPL Financial LLC | 0 | 35,621 | +35,621 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 51,589 | 35,615 | -15,974 | 0.01 | 0.01 | +0.00 | sell |
| TD ASSET MANAGEMENT INC | 34,884 | 34,884 | 0 | 0.00 | 0.00 | +0.00 | hold |
| AMERIPRISE FINANCIAL INC | 0 | 34,407 | +34,407 | 0.00 | 0.00 | +0.00 | buy |
| Legal Advantage Investments, Inc. | 34,500 | 34,100 | -400 | 0.80 | 1.39 | +0.58 | sell |
| Quadrature Capital Ltd | 0 | 34,086 | +34,086 | 0.00 | 0.05 | +0.05 | buy |
| ROYCE & ASSOCIATES LP | 28,293 | 31,567 | +3,274 | 0.01 | 0.02 | +0.01 | buy |
| Engineers Gate Manager LP | 10,523 | 29,690 | +19,167 | 0.01 | 0.04 | +0.03 | buy |
| Ensign Peak Advisors, Inc | 0 | 26,900 | +26,900 | 0.00 | 0.00 | +0.00 | buy |
| Verition Fund Management LLC | 25,845 | 26,776 | +931 | 0.01 | 0.01 | +0.00 | buy |
| JANE STREET GROUP, LLC | 13,476 | 25,699 | +12,223 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 40,953 | 24,402 | -16,551 | 0.00 | 0.00 | +0.00 | sell |
| Swiss National Bank | 20,400 | 23,800 | +3,400 | 0.00 | 0.00 | +0.00 | buy |
| Cubist Systematic Strategies, LLC | 124,718 | 22,804 | -101,914 | 0.08 | 0.03 | -0.05 | sell |
| Alphabet Inc. | 22,711 | 22,711 | 0 | 0.05 | 0.10 | +0.05 | hold |
| ROYAL BANK OF CANADA | 12,334 | 22,639 | +10,305 | 0.00 | 0.00 | +0.00 | buy |
| THOMPSON DAVIS & CO., INC. | 14,600 | 21,130 | +6,530 | 0.46 | 1.04 | +0.59 | buy |
| Alpine Global Management, LLC | 20,000 | 20,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| RHUMBLINE ADVISERS | 18,729 | 19,750 | +1,021 | 0.00 | 0.00 | +0.00 | buy |
| NIA IMPACT ADVISORS, LLC | 0 | 19,256 | +19,256 | 0.00 | 0.48 | +0.48 | buy |
| SEI INVESTMENTS CO | 0 | 18,012 | +18,012 | 0.00 | 0.00 | +0.00 | buy |
| Graham Capital Management, L.P. | 12,584 | 17,453 | +4,869 | 0.02 | 0.04 | +0.02 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 7,647 | 16,849 | +9,202 | 0.00 | 0.00 | +0.00 | buy |
| Gotham Asset Management, LLC | 13,478 | 16,587 | +3,109 | 0.01 | 0.01 | +0.01 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 14,240 | 15,751 | +1,511 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 15,509 | 14,434 | -1,075 | 0.00 | 0.00 | +0.00 | sell |
| DIMENSIONAL FUND ADVISORS LP | 0 | 14,054 | +14,054 | 0.00 | 0.00 | +0.00 | buy |