| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| DEERFIELD MANAGEMENT COMPANY, L.P. | 0 | 1,616,778 | +1,616,778 | 0.00 | 0.47 | +0.47 | buy |
| JANUS HENDERSON GROUP PLC | 535,552 | 1,639,351 | +1,103,799 | 0.00 | 0.01 | +0.01 | buy |
| FMR LLC | 20,633 | 920,239 | +899,606 | 0.00 | 0.00 | +0.00 | buy |
| FARALLON CAPITAL MANAGEMENT LLC | 3,290,956 | 3,990,956 | +700,000 | 0.20 | 0.32 | +0.11 | buy |
| Opaleye Management Inc. | 1,698,142 | 2,260,000 | +561,858 | 3.49 | 7.42 | +3.93 | buy |
| BANK OF AMERICA CORP /DE/ | 200,740 | 746,872 | +546,132 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 346,654 | 750,787 | +404,133 | 0.01 | 0.02 | +0.01 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 84,376 | 461,248 | +376,872 | 0.00 | 0.01 | +0.01 | buy |
| MORGAN STANLEY | 413,347 | 691,330 | +277,983 | 0.00 | 0.00 | +0.00 | buy |
| SILVERARC CAPITAL MANAGEMENT, LLC | 0 | 214,057 | +214,057 | 0.00 | 0.66 | +0.66 | buy |
| JANE STREET GROUP, LLC | 89,651 | 293,627 | +203,976 | 0.00 | 0.01 | +0.01 | buy |
| D. E. Shaw & Co., Inc. | 12,097 | 164,374 | +152,277 | 0.00 | 0.00 | +0.00 | buy |
| DARK FOREST CAPITAL MANAGEMENT LP | 52,363 | 201,103 | +148,740 | 0.09 | 0.14 | +0.05 | buy |
| MARSHALL WACE, LLP | 286,289 | 416,527 | +130,238 | 0.00 | 0.01 | +0.00 | buy |
| CenterBook Partners LP | 0 | 121,072 | +121,072 | 0.00 | 0.11 | +0.11 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 120,369 | +120,369 | 0.00 | 0.00 | +0.00 | buy |
| CITADEL ADVISORS LLC | 392,564 | 506,558 | +113,994 | 0.00 | 0.01 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 181,800 | 287,800 | +106,000 | 0.00 | 0.01 | +0.00 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 558,658 | 662,873 | +104,215 | 0.20 | 0.34 | +0.14 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 86,882 | 187,718 | +100,836 | 0.00 | 0.00 | +0.00 | buy |
| TANG CAPITAL MANAGEMENT LLC | 1,100,000 | 1,200,000 | +100,000 | 0.86 | 0.98 | +0.12 | buy |
| GOLDMAN SACHS GROUP INC | 778,276 | 861,231 | +82,955 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 44,753 | 125,121 | +80,368 | 0.00 | 0.00 | +0.00 | buy |
| BlackRock, Inc. | 4,661,563 | 4,731,960 | +70,397 | 0.00 | 0.00 | +0.00 | buy |
| SG Americas Securities, LLC | 0 | 61,735 | +61,735 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 381,237 | 434,090 | +52,853 | 0.01 | 0.01 | +0.00 | buy |
| SIMPLEX TRADING, LLC | 40,234 | 79,027 | +38,793 | 0.01 | 0.04 | +0.03 | buy |
| RAYMOND JAMES FINANCIAL INC | 18,507 | 53,575 | +35,068 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 28,205 | 62,523 | +34,318 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,339,254 | 1,373,248 | +33,994 | 0.00 | 0.00 | +0.00 | buy |
| BANCO BILBAO VIZCAYA ARGENTARIA, S.A. | 0 | 30,000 | +30,000 | 0.00 | 0.00 | +0.00 | buy |
| Kovitz Investment Group Partners, LLC | 0 | 26,000 | +26,000 | 0.00 | 0.00 | +0.00 | buy |
| Family Management Corp | 0 | 25,200 | +25,200 | 0.00 | 0.06 | +0.06 | buy |
| ExodusPoint Capital Management, LP | 60,770 | 85,479 | +24,709 | 0.01 | 0.02 | +0.01 | buy |
| Campbell & CO Investment Adviser LLC | 0 | 24,673 | +24,673 | 0.00 | 0.03 | +0.03 | buy |
| Creative Planning | 145 | 19,075 | +18,930 | 0.00 | 0.00 | +0.00 | buy |
| WOLVERINE TRADING, LLC | 0 | 17,208 | +17,208 | 0.00 | 0.01 | +0.01 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 179,999 | 196,226 | +16,227 | 0.00 | 0.00 | +0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 105,734 | 121,756 | +16,022 | 0.00 | 0.00 | +0.00 | buy |
| ACUTA CAPITAL PARTNERS, LLC | 137,709 | 153,482 | +15,773 | 1.63 | 2.63 | +1.00 | buy |
| Virtus Investment Advisers, LLC | 0 | 14,910 | +14,910 | 0.00 | 0.06 | +0.06 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 21,867 | 36,065 | +14,198 | 0.00 | 0.00 | +0.00 | buy |
| CIBC WORLD MARKETS CORP | 0 | 14,066 | +14,066 | 0.00 | 0.00 | +0.00 | buy |
| ROYAL BANK OF CANADA | 0 | 11,936 | +11,936 | 0.00 | 0.00 | +0.00 | buy |
| SCOTIA CAPITAL INC. | 0 | 10,809 | +10,809 | 0.00 | 0.00 | +0.00 | buy |
| Cetera Investment Advisers | 31,243 | 41,999 | +10,756 | 0.00 | 0.00 | +0.00 | buy |
| AIGEN INVESTMENT MANAGEMENT, LP | 0 | 10,213 | +10,213 | 0.00 | 0.02 | +0.02 | buy |
| AMERIPRISE FINANCIAL INC | 0 | 10,161 | +10,161 | 0.00 | 0.00 | +0.00 | buy |
| CORSAIR CAPITAL MANAGEMENT, L.P. | 0 | 10,000 | +10,000 | 0.00 | 0.04 | +0.04 | buy |
| Whitcomb & Hess, Inc. | 11,495 | 21,300 | +9,805 | 0.04 | 0.10 | +0.05 | buy |
| Bank of New York Mellon Corp | 188,584 | 194,131 | +5,547 | 0.00 | 0.00 | +0.00 | buy |
| Quarry LP | 0 | 5,389 | +5,389 | 0.00 | 0.02 | +0.02 | buy |
| RHUMBLINE ADVISERS | 80,652 | 85,463 | +4,811 | 0.00 | 0.00 | +0.00 | buy |
| Walleye Capital LLC | 29,293 | 33,521 | +4,228 | 0.00 | 0.01 | +0.00 | buy |
| Squarepoint Ops LLC | 98,189 | 102,260 | +4,071 | 0.00 | 0.00 | +0.00 | buy |
| OSAIC HOLDINGS, INC. | 0 | 3,719 | +3,719 | 0.00 | 0.00 | +0.00 | buy |
| COMMONWEALTH EQUITY SERVICES, LLC | 10,342 | 13,633 | +3,291 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 24,623 | 27,377 | +2,754 | 0.00 | 0.00 | +0.00 | buy |
| TUDOR INVESTMENT CORP ET AL | 38,619 | 40,959 | +2,340 | 0.00 | 0.01 | +0.00 | buy |
| Hurley Capital, LLC | 0 | 2,160 | +2,160 | 0.00 | 0.02 | +0.02 | buy |
| LPL Financial LLC | 12,320 | 14,420 | +2,100 | 0.00 | 0.00 | +0.00 | buy |
| Significant Wealth Partners LLC | 12,616 | 14,396 | +1,780 | 0.08 | 0.11 | +0.03 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 35,981 | 37,681 | +1,700 | 0.00 | 0.00 | +0.00 | buy |
| Bleakley Financial Group, LLC | 23,785 | 25,308 | +1,523 | 0.01 | 0.01 | +0.00 | buy |
| Valmark Advisers, Inc. | 17,358 | 18,641 | +1,283 | 0.00 | 0.00 | +0.00 | buy |
| Mariner, LLC | 19,688 | 20,935 | +1,247 | 0.00 | 0.00 | +0.00 | buy |
| GAMMA Investing LLC | 1,788 | 2,961 | +1,173 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 769 | 1,752 | +983 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 30,020 | 30,979 | +959 | 0.00 | 0.00 | +0.00 | buy |
| Advisory Services Network, LLC | 66,445 | 67,180 | +735 | 0.01 | 0.02 | +0.00 | buy |
| DMC Group, LLC | 16,302 | 16,881 | +579 | 0.16 | 0.20 | +0.05 | buy |
| AMALGAMATED BANK | 1,656 | 2,195 | +539 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 91,541 | 91,997 | +456 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 146 | 502 | +356 | 0.00 | 0.00 | +0.00 | buy |
| MassMutual Private Wealth & Trust, FSB | 0 | 300 | +300 | 0.00 | 0.00 | +0.00 | buy |
| Caitong International Asset Management Co., Ltd | 0 | 163 | +163 | 0.00 | 0.00 | +0.00 | buy |
| PNC FINANCIAL SERVICES GROUP, INC. | 5,480 | 5,594 | +114 | 0.00 | 0.00 | +0.00 | buy |
| Sigma Planning Corp | 65,210 | 65,275 | +65 | 0.02 | 0.03 | +0.01 | buy |
| Ballentine Partners, LLC | 10,960 | 11,020 | +60 | 0.00 | 0.00 | +0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 323 | 378 | +55 | 0.00 | 0.00 | +0.00 | buy |
| Parkside Financial Bank & Trust | 0 | 50 | +50 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 4 | 52 | +48 | 0.00 | 0.00 | +0.00 | buy |
| ROTHSCHILD INVESTMENT LLC | 115 | 155 | +40 | 0.00 | 0.00 | +0.00 | buy |
| Larson Financial Group LLC | 0 | 38 | +38 | 0.00 | 0.00 | +0.00 | buy |
| Brooklyn Investment Group | 0 | 36 | +36 | 0.00 | 0.00 | +0.00 | buy |
| Farther Finance Advisors, LLC | 105 | 141 | +36 | 0.00 | 0.00 | +0.00 | buy |
| Stephens Consulting, LLC | 0 | 25 | +25 | 0.00 | 0.00 | +0.00 | buy |
| Birchview Capital, LP | 10,000 | 10,013 | +13 | 0.10 | 0.13 | +0.03 | buy |
| SBI Securities Co., Ltd. | 0 | 3 | +3 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 6,632 | 6,632 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 51,928 | 51,928 | 0 | 0.00 | 0.00 | +0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 66,150 | 66,150 | 0 | 0.00 | 0.00 | +0.00 | hold |
| GREENLEAF TRUST | 14,016 | 14,016 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Sterling Capital Management LLC | 70 | 70 | 0 | 0.00 | 0.00 | +0.00 | hold |
| HighVista Strategies LLC | 203,510 | 203,510 | 0 | 0.89 | 1.16 | +0.27 | hold |
| SIGNATUREFD, LLC | 10,000 | 10,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| MIRABELLA FINANCIAL SERVICES LLP | 500,000 | 500,000 | 0 | 0.54 | 0.30 | -0.24 | hold |
| Allworth Financial LP | 12 | 12 | 0 | 0.00 | 0.00 | +0.00 | hold |
| HARBERT FUND ADVISORS, INC. | 339,158 | 339,158 | 0 | 3.47 | 5.80 | +2.33 | hold |
| IFP Advisors, Inc | 0 | 0 | 0 | 0.00 | 0.00 | +0.00 | hold |