| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| TORONTO DOMINION BANK | 0 | 1,909,228 | +1,909,228 | 0.00 | 0.20 | +0.20 | buy |
| LORD, ABBETT & CO. LLC | 594,876 | 1,279,987 | +685,111 | 0.06 | 0.22 | +0.16 | buy |
| MILLENNIUM MANAGEMENT LLC | 222,515 | 644,010 | +421,495 | 0.01 | 0.03 | +0.02 | buy |
| GILDER GAGNON HOWE & CO LLC | 7,047 | 404,237 | +397,190 | 0.00 | 0.24 | +0.24 | buy |
| JENNISON ASSOCIATES LLC | 2,178,580 | 2,500,132 | +321,552 | 0.04 | 0.08 | +0.04 | buy |
| Invesco Ltd. | 682,097 | 932,115 | +250,018 | 0.00 | 0.01 | +0.01 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 239,315 | 460,773 | +221,458 | 0.00 | 0.00 | +0.00 | buy |
| MACQUARIE GROUP LTD | 594,878 | 815,912 | +221,034 | 0.02 | 0.05 | +0.03 | buy |
| D. E. Shaw & Co., Inc. | 182,095 | 365,544 | +183,449 | 0.01 | 0.02 | +0.01 | buy |
| Atika Capital Management LLC | 0 | 177,200 | +177,200 | 0.00 | 1.27 | +1.27 | buy |
| Cutter Capital Management, LP | 0 | 112,500 | +112,500 | 0.00 | 2.55 | +2.55 | buy |
| Rock Springs Capital Management LP | 0 | 110,889 | +110,889 | 0.00 | 0.23 | +0.23 | buy |
| BANK OF AMERICA CORP /DE/ | 233,468 | 337,856 | +104,388 | 0.00 | 0.00 | +0.00 | buy |
| Paradigm Biocapital Advisors LP | 2,440,445 | 2,531,896 | +91,451 | 2.81 | 4.88 | +2.07 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 600 | 82,300 | +81,700 | 0.00 | 0.00 | +0.00 | buy |
| FEDERATED HERMES, INC. | 0 | 77,714 | +77,714 | 0.00 | 0.01 | +0.01 | buy |
| DEUTSCHE BANK AG\ | 79,166 | 153,441 | +74,275 | 0.00 | 0.00 | +0.00 | buy |
| Informed Momentum Co LLC | 0 | 71,815 | +71,815 | 0.00 | 0.56 | +0.56 | buy |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 0 | 59,204 | +59,204 | 0.00 | 0.40 | +0.40 | buy |
| Lisanti Capital Growth, LLC | 39,845 | 96,935 | +57,090 | 0.33 | 1.29 | +0.96 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 12,454 | 64,123 | +51,669 | 0.00 | 0.01 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 268,775 | 318,730 | +49,955 | 0.00 | 0.00 | +0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 103,495 | 148,735 | +45,240 | 0.00 | 0.01 | +0.01 | buy |
| NORTHERN TRUST CORP | 317,555 | 357,616 | +40,061 | 0.00 | 0.00 | +0.00 | buy |
| Woodline Partners LP | 71,569 | 108,986 | +37,417 | 0.02 | 0.04 | +0.02 | buy |
| Qube Research & Technologies Ltd | 64,683 | 97,996 | +33,313 | 0.00 | 0.01 | +0.00 | buy |
| JANE STREET GROUP, LLC | 27,581 | 57,256 | +29,675 | 0.00 | 0.01 | +0.00 | buy |
| FMR LLC | 5,032 | 33,827 | +28,795 | 0.00 | 0.00 | +0.00 | buy |
| BLAIR WILLIAM & CO/IL | 0 | 27,230 | +27,230 | 0.00 | 0.00 | +0.00 | buy |
| SILVERARC CAPITAL MANAGEMENT, LLC | 40,000 | 65,955 | +25,955 | 0.30 | 0.82 | +0.52 | buy |
| TD ASSET MANAGEMENT INC | 29,788 | 54,988 | +25,200 | 0.00 | 0.00 | +0.00 | buy |
| Advisory Services Network, LLC | 37,811 | 60,459 | +22,648 | 0.02 | 0.06 | +0.04 | buy |
| Artia Global Partners LP | 0 | 20,811 | +20,811 | 0.00 | 0.46 | +0.46 | buy |
| AIGH Capital Management LLC | 204,413 | 224,713 | +20,300 | 3.15 | 4.68 | +1.54 | buy |
| Numerai GP LLC | 0 | 18,668 | +18,668 | 0.00 | 0.28 | +0.28 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 12,033 | 30,033 | +18,000 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 2,097,323 | 2,115,162 | +17,839 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 899,379 | 916,856 | +17,477 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 39,553 | 57,004 | +17,451 | 0.00 | 0.00 | +0.00 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 15,118 | +15,118 | 0.00 | 0.06 | +0.06 | buy |
| TUDOR INVESTMENT CORP ET AL | 0 | 13,880 | +13,880 | 0.00 | 0.01 | +0.01 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 32,929 | 46,777 | +13,848 | 0.00 | 0.00 | +0.00 | buy |
| SEI INVESTMENTS CO | 35,491 | 48,180 | +12,689 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 0 | 11,375 | +11,375 | 0.00 | 0.05 | +0.05 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 58,835 | 69,826 | +10,991 | 0.00 | 0.00 | +0.00 | buy |
| SECTORAL ASSET MANAGEMENT INC | 11,300 | 20,300 | +9,000 | 0.22 | 0.75 | +0.53 | buy |
| AMERIPRISE FINANCIAL INC | 39,349 | 47,685 | +8,336 | 0.00 | 0.00 | +0.00 | buy |
| Alpha DNA Investment Management LLC | 0 | 7,818 | +7,818 | 0.00 | 0.24 | +0.24 | buy |
| AIGEN INVESTMENT MANAGEMENT, LP | 0 | 7,504 | +7,504 | 0.00 | 0.07 | +0.07 | buy |
| OMERS ADMINISTRATION Corp | 0 | 7,400 | +7,400 | 0.00 | 0.00 | +0.00 | buy |
| Capula Management Ltd | 0 | 6,396 | +6,396 | 0.00 | 0.00 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 8,572 | 14,681 | +6,109 | 0.00 | 0.01 | +0.00 | buy |
| NATIONS FINANCIAL GROUP INC, /IA/ /ADV | 0 | 6,000 | +6,000 | 0.00 | 0.02 | +0.02 | buy |
| Bleakley Financial Group, LLC | 0 | 5,825 | +5,825 | 0.00 | 0.01 | +0.01 | buy |
| Assenagon Asset Management S.A. | 1,141,247 | 1,146,812 | +5,565 | 0.08 | 0.11 | +0.04 | buy |
| Voleon Capital Management LP | 0 | 5,266 | +5,266 | 0.00 | 0.02 | +0.02 | buy |
| STRS OHIO | 0 | 5,200 | +5,200 | 0.00 | 0.00 | +0.00 | buy |
| Pictet Asset Management Holding SA | 0 | 5,130 | +5,130 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 0 | 4,848 | +4,848 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 33,435 | 38,208 | +4,773 | 0.00 | 0.00 | +0.00 | buy |
| THOROUGHBRED FINANCIAL SERVICES, LLC | 0 | 4,745 | +4,745 | 0.00 | 0.02 | +0.02 | buy |
| Corton Capital Inc. | 0 | 4,714 | +4,714 | 0.00 | 0.15 | +0.15 | buy |
| Baader Bank Aktiengesellschaft | 0 | 4,500 | +4,500 | 0.00 | 0.02 | +0.02 | buy |
| Marex Group plc | 0 | 4,400 | +4,400 | 0.00 | 0.00 | +0.00 | buy |
| Bayesian Capital Management, LP | 0 | 4,114 | +4,114 | 0.00 | 0.03 | +0.03 | buy |
| OPPENHEIMER & CO INC | 0 | 4,100 | +4,100 | 0.00 | 0.00 | +0.00 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 0 | 4,031 | +4,031 | 0.00 | 0.00 | +0.00 | buy |
| HARBOR CAPITAL ADVISORS, INC. | 18,105 | 22,113 | +4,008 | 0.03 | 0.05 | +0.03 | buy |
| JANUS HENDERSON GROUP PLC | 8,482 | 12,482 | +4,000 | 0.00 | 0.00 | +0.00 | buy |
| Centiva Capital, LP | 0 | 3,959 | +3,959 | 0.00 | 0.01 | +0.01 | buy |
| HighTower Advisors, LLC | 0 | 3,734 | +3,734 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 290,009 | 293,700 | +3,691 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 835,790 | 838,804 | +3,014 | 0.00 | 0.00 | +0.00 | buy |
| Quarry LP | 0 | 3,000 | +3,000 | 0.00 | 0.03 | +0.03 | buy |
| ProShare Advisors LLC | 9,200 | 12,170 | +2,970 | 0.00 | 0.00 | +0.00 | buy |
| KEYBANK NATIONAL ASSOCIATION/OH | 9,979 | 12,383 | +2,404 | 0.00 | 0.00 | +0.00 | buy |
| Creative Planning | 11,002 | 13,177 | +2,175 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 24,579 | 26,595 | +2,016 | 0.00 | 0.00 | +0.00 | buy |
| ALPS ADVISORS INC | 29,242 | 30,906 | +1,664 | 0.01 | 0.01 | +0.00 | buy |
| Legato Capital Management LLC | 44,160 | 45,656 | +1,496 | 0.18 | 0.33 | +0.15 | buy |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 6,633 | 7,904 | +1,271 | 0.00 | 0.00 | +0.00 | buy |
| MetLife Investment Management, LLC | 21,504 | 22,678 | +1,174 | 0.00 | 0.01 | +0.00 | buy |
| RHUMBLINE ADVISERS | 48,515 | 49,534 | +1,019 | 0.00 | 0.00 | +0.00 | buy |
| China Universal Asset Management Co., Ltd. | 7,317 | 8,106 | +789 | 0.03 | 0.04 | +0.02 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 20,202 | 20,926 | +724 | 0.00 | 0.00 | +0.00 | buy |
| Swiss National Bank | 51,733 | 52,333 | +600 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 101,430 | 101,928 | +498 | 0.00 | 0.00 | +0.00 | buy |
| SHERBROOKE PARK ADVISERS LLC | 6,128 | 6,571 | +443 | 0.05 | 0.12 | +0.07 | buy |
| Brooklyn Investment Group | 0 | 370 | +370 | 0.00 | 0.01 | +0.01 | buy |
| MAI Capital Management | 0 | 285 | +285 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 3,604 | 3,848 | +244 | 0.00 | 0.01 | +0.00 | buy |
| Aster Capital Management (DIFC) Ltd | 0 | 218 | +218 | 0.00 | 0.00 | +0.00 | buy |
| SUMMIT SECURITIES GROUP LLC | 0 | 157 | +157 | 0.00 | 0.00 | +0.00 | buy |
| Accent Capital Management, LLC | 0 | 105 | +105 | 0.00 | 0.00 | +0.00 | buy |
| Arizona State Retirement System | 7,615 | 7,712 | +97 | 0.00 | 0.00 | +0.00 | buy |
| COMERICA BANK | 89 | 173 | +84 | 0.00 | 0.00 | +0.00 | buy |
| QUADRANT CAPITAL GROUP LLC | 6 | 89 | +83 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 2,111 | 2,167 | +56 | 0.00 | 0.00 | +0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 100 | 149 | +49 | 0.00 | 0.00 | +0.00 | buy |
| Amundi | 0 | 47 | +47 | 0.00 | 0.00 | +0.00 | buy |