| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| RAYMOND JAMES FINANCIAL INC | 2,029,383 | 2,218,352 | +188,969 | 0.00 | 0.00 | -0.00 | buy |
| DAFNA Capital Management LLC | 186,717 | 304,752 | +118,035 | 0.22 | 0.32 | +0.09 | buy |
| SCS Capital Management LLC | 0 | 106,980 | +106,980 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 1,749,660 | 1,834,628 | +84,968 | 0.00 | 0.00 | -0.00 | buy |
| Squarepoint Ops LLC | 0 | 44,040 | +44,040 | 0.00 | 0.00 | +0.00 | buy |
| Brevan Howard Capital Management LP | 0 | 28,606 | +28,606 | 0.00 | 0.00 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 0 | 20,475 | +20,475 | 0.00 | 0.00 | +0.00 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 41,144 | 61,544 | +20,400 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 567,367 | 586,217 | +18,850 | 0.00 | 0.00 | -0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 0 | 18,693 | +18,693 | 0.00 | 0.00 | +0.00 | buy |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 223,780 | 241,816 | +18,036 | 0.00 | 0.00 | -0.00 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 87,069 | 102,888 | +15,819 | 0.00 | 0.00 | -0.00 | buy |
| EXCHANGE TRADED CONCEPTS, LLC | 18,085 | 27,693 | +9,608 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 47,736 | 57,236 | +9,500 | 0.00 | 0.00 | -0.00 | buy |
| DEUTSCHE BANK AG\ | 12,310 | 20,890 | +8,580 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 682,863 | 690,695 | +7,832 | 0.00 | 0.00 | -0.00 | buy |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 33,500 | 39,100 | +5,600 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 2,104 | 3,890 | +1,786 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 18 | 1,792 | +1,774 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 49,643 | 51,098 | +1,455 | 0.00 | 0.00 | -0.00 | buy |
| SIMPLEX TRADING, LLC | 680 | 1,782 | +1,102 | 0.00 | 0.00 | +0.00 | buy |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 0 | 869 | +869 | 0.00 | 0.00 | +0.00 | buy |
| SG Americas Securities, LLC | 11,398 | 12,118 | +720 | 0.00 | 0.00 | -0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 14,472 | 15,096 | +624 | 0.00 | 0.00 | -0.00 | buy |
| WELLS FARGO & COMPANY/MN | 15,841 | 16,136 | +295 | 0.00 | 0.00 | -0.00 | buy |
| GF FUND MANAGEMENT CO. LTD. | 1,167 | 1,424 | +257 | 0.00 | 0.00 | +0.00 | buy |
| SBI Securities Co., Ltd. | 1 | 100 | +99 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 0 | 96 | +96 | 0.00 | 0.00 | +0.00 | buy |
| True Wealth Design, LLC | 0 | 81 | +81 | 0.00 | 0.00 | +0.00 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 15,851 | 15,874 | +23 | 0.00 | 0.00 | -0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 1,853 | 1,861 | +8 | 0.00 | 0.00 | -0.00 | buy |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 3,255,514 | 3,255,514 | 0 | 0.29 | 0.24 | -0.06 | hold |
| Ameritas Investment Partners, Inc. | 1,534 | 1,534 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BVF INC/IL | 5,302,000 | 5,302,000 | 0 | 0.85 | 0.79 | -0.06 | hold |
| WASHINGTON TRUST Co | 1,500 | 1,500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 1,830 | 1,830 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 17,380 | 17,380 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Flagship Pioneering Inc. | 12,674,120 | 12,674,120 | 0 | 17.90 | 19.62 | +1.72 | hold |
| Sio Capital Management, LLC | 121,672 | 121,672 | 0 | 0.16 | 0.13 | -0.03 | hold |
| Birchview Capital, LP | 310,930 | 310,930 | 0 | 1.19 | 0.99 | -0.21 | hold |
| Sunbelt Securities, Inc. | 1,000 | 1,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| IFP Advisors, Inc | 2 | 2 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Alphabet Inc. | 500,901 | 500,901 | 0 | 0.14 | 0.12 | -0.02 | hold |
| Euclidean Capital LLC | 1,573,761 | 1,573,761 | 0 | 1.01 | 2.16 | +1.15 | hold |
| TFC Financial Management, Inc. | 123 | 123 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Alta Wealth Advisors LLC | 15,032 | 15,032 | 0 | 0.03 | 0.03 | -0.01 | hold |
| Rockwood Wealth Management, LLC | 107,329 | 107,329 | 0 | 0.05 | 0.04 | -0.01 | hold |
| Siren, L.L.C. | 720,720 | 720,720 | 0 | 0.15 | 0.15 | -0.00 | hold |
| Police & Firemen's Retirement System of New Jersey | 5,078 | 5,078 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Wingate Wealth Advisors, Inc. | 28,471 | 28,471 | 0 | 0.13 | 0.12 | -0.01 | hold |
| Evelyn Partners Asset Management Ltd | 7,100 | 7,100 | 0 | 0.01 | 0.01 | -0.00 | hold |
| FIDUCIARY TRUST CO | 10,879 | 10,879 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| Legal & General Group Plc | 2,706 | 2,706 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 1,871 | 1,871 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 75,495 | 75,495 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AMALGAMATED BANK | 681 | 681 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Bank of New York Mellon Corp | 58,312 | 58,311 | -1 | 0.00 | 0.00 | -0.00 | sell |
| GAMMA Investing LLC | 111 | 96 | -15 | 0.00 | 0.00 | -0.00 | sell |
| HSBC HOLDINGS PLC | 18,728 | 18,709 | -19 | 0.00 | 0.00 | -0.00 | sell |
| R Squared Ltd | 30 | 0 | -30 | 0.00 | 0.00 | -0.00 | sell |
| NISA INVESTMENT ADVISORS, LLC | 5,087 | 5,057 | -30 | 0.00 | 0.00 | -0.00 | sell |
| Russell Investments Group, Ltd. | 1,477 | 1,371 | -106 | 0.00 | 0.00 | -0.00 | sell |
| Point72 (DIFC) Ltd | 509 | 376 | -133 | 0.00 | 0.00 | -0.00 | sell |
| RHUMBLINE ADVISERS | 36,384 | 36,245 | -139 | 0.00 | 0.00 | -0.00 | sell |
| Sterling Capital Management LLC | 354 | 188 | -166 | 0.00 | 0.00 | -0.00 | sell |
| Corebridge Financial, Inc. | 12,557 | 12,373 | -184 | 0.00 | 0.00 | -0.00 | sell |
| China Universal Asset Management Co., Ltd. | 11,788 | 11,155 | -633 | 0.01 | 0.00 | -0.00 | sell |
| LAZARD ASSET MANAGEMENT LLC | 10,582 | 9,808 | -774 | 0.00 | 0.00 | -0.00 | sell |
| PANAGORA ASSET MANAGEMENT INC | 55,154 | 54,335 | -819 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 20,032 | 18,834 | -1,198 | 0.00 | 0.00 | -0.00 | sell |
| Walleye Capital LLC | 34,048 | 32,839 | -1,209 | 0.00 | 0.00 | -0.00 | sell |
| SHERBROOKE PARK ADVISERS LLC | 15,617 | 13,075 | -2,542 | 0.02 | 0.02 | -0.00 | sell |
| NORTHERN TRUST CORP | 253,671 | 247,305 | -6,366 | 0.00 | 0.00 | -0.00 | sell |
| Point72 Asset Management, L.P. | 634,761 | 625,217 | -9,544 | 0.01 | 0.01 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 12,946 | 3,166 | -9,780 | 0.00 | 0.00 | -0.00 | sell |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 10,295 | 0 | -10,295 | 0.00 | 0.00 | -0.00 | sell |
| Cubist Systematic Strategies, LLC | 10,895 | 0 | -10,895 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 51,609 | 39,890 | -11,719 | 0.00 | 0.00 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 74,656 | 56,332 | -18,324 | 0.00 | 0.00 | -0.00 | sell |
| Trexquant Investment LP | 61,598 | 35,585 | -26,013 | 0.00 | 0.00 | -0.00 | sell |
| ACADIAN ASSET MANAGEMENT LLC | 35,784 | 9,495 | -26,289 | 0.00 | 0.00 | -0.00 | sell |
| BlackRock, Inc. | 2,029,208 | 1,995,901 | -33,307 | 0.00 | 0.00 | -0.00 | sell |
| Corton Capital Inc. | 34,576 | 0 | -34,576 | 0.09 | 0.00 | -0.09 | sell |
| JPMORGAN CHASE & CO | 56,531 | 16,126 | -40,405 | 0.00 | 0.00 | -0.00 | sell |
| BAKER BROS. ADVISORS LP | 45,027 | 0 | -45,027 | 0.00 | 0.00 | -0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 92,640 | 20,656 | -71,984 | 0.00 | 0.00 | -0.00 | sell |
| D. E. Shaw & Co., Inc. | 100,367 | 14,875 | -85,492 | 0.00 | 0.00 | -0.00 | sell |
| FMR LLC | 5,689,719 | 5,588,874 | -100,845 | 0.00 | 0.00 | -0.00 | sell |