| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ArrowMark Colorado Holdings LLC | 0 | 108,333 | +108,333 | 0.00 | 0.00 | +0.00 | buy |
| Euclidean Capital LLC | 0 | 87,696 | +87,696 | 0.00 | 0.09 | +0.09 | buy |
| ArrowMark Colorado Holdings LLC | 0 | 55,123 | +55,123 | 0.00 | 0.01 | +0.01 | buy |
| Board of Trustees of The Leland Stanford Junior University | 0 | 52,131 | +52,131 | 0.00 | 0.03 | +0.03 | buy |
| Trustees of Columbia University in the City of New York | 0 | 47,930 | +47,930 | 0.00 | 0.95 | +0.95 | buy |
| VANGUARD GROUP INC | 0 | 32,511 | +32,511 | 0.00 | 0.00 | +0.00 | buy |
| Alyeska Investment Group, L.P. | 0 | 20,376 | +20,376 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 0 | 11,473 | +11,473 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 10,326 | +10,326 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 0 | 612 | +612 | 0.00 | 0.00 | +0.00 | buy |
| WOLVERINE ASSET MANAGEMENT LLC | 0 | 281 | +281 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 17,220 | 17,322 | +102 | 0.00 | 0.00 | 0.00 | buy |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 166,666 | 166,666 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CANTOR FITZGERALD, L. P. | 35,200 | 35,200 | 0 | 0.00 | 0.00 | +0.00 | hold |
| BRIDGER MANAGEMENT, LLC | 466,666 | 466,666 | 0 | 0.01 | 0.00 | -0.00 | hold |
| PERCEPTIVE ADVISORS LLC | 166,666 | 166,666 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BAKER BROS. ADVISORS LP | 833,333 | 833,333 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PRELUDE CAPITAL MANAGEMENT, LLC | 24,614 | 24,614 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Trustees of Columbia University in the City of New York | 33,333 | 33,333 | 0 | 0.00 | 0.00 | -0.00 | hold |
| LMR Partners LLP | 648,285 | 648,285 | 0 | 0.00 | 0.00 | -0.00 | hold |
| EcoR1 Capital, LLC | 66,665 | 66,665 | 0 | 0.00 | 0.02 | +0.02 | hold |
| Samsara BioCapital, LLC | 99,999 | 99,999 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Altium Capital Management LLC | 82,233 | 82,233 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Euclidean Capital LLC | 170,833 | 170,833 | 0 | 0.00 | 0.00 | -0.00 | hold |
| HIGHBRIDGE CAPITAL MANAGEMENT LLC | 0 | 0 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CLEAR STREET LLC | 100 | 66 | -34 | 0.00 | 0.00 | -0.00 | sell |
| WOLVERINE ASSET MANAGEMENT LLC | 7,725 | 0 | -7,725 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 8,738 | 0 | -8,738 | 0.00 | 0.00 | -0.00 | sell |
| PRUDENTIAL FINANCIAL INC | 10,000 | 0 | -10,000 | 0.00 | 0.00 | -0.00 | sell |
| Virtu Financial LLC | 12,154 | 0 | -12,154 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 14,494 | 0 | -14,494 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 35,833 | 0 | -35,833 | 0.00 | 0.00 | -0.00 | sell |
| BRIDGER MANAGEMENT, LLC | 61,699 | 0 | -61,699 | 0.01 | 0.00 | -0.01 | sell |
| PRELUDE CAPITAL MANAGEMENT, LLC | 61,699 | 0 | -61,699 | 0.00 | 0.00 | -0.00 | sell |
| STATE STREET CORP | 70,932 | 0 | -70,932 | 0.00 | 0.00 | -0.00 | sell |
| Monashee Investment Management LLC | 82,986 | 0 | -82,986 | 0.00 | 0.00 | -0.00 | sell |
| BML Capital Management, LLC | 89,271 | 0 | -89,271 | 0.04 | 0.00 | -0.04 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 124,598 | 0 | -124,598 | 0.00 | 0.00 | -0.00 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 172,148 | 0 | -172,148 | 0.00 | 0.00 | -0.00 | sell |
| Alyeska Investment Group, L.P. | 305,648 | 0 | -305,648 | 0.00 | 0.00 | -0.00 | sell |
| HHLR ADVISORS, LTD. | 384,573 | 0 | -384,573 | 0.00 | 0.00 | -0.00 | sell |
| VANGUARD GROUP INC | 487,698 | 0 | -487,698 | 0.00 | 0.00 | -0.00 | sell |
| Trustees of Columbia University in the City of New York | 718,950 | 0 | -718,950 | 0.65 | 0.00 | -0.65 | sell |
| Board of Trustees of The Leland Stanford Junior University | 781,960 | 0 | -781,960 | 0.03 | 0.00 | -0.03 | sell |
| HARVARD MANAGEMENT CO INC | 826,852 | 0 | -826,852 | 0.05 | 0.00 | -0.05 | sell |
| Euclidean Capital LLC | 1,315,463 | 0 | -1,315,463 | 0.14 | 0.00 | -0.14 | sell |
| Column Group LLC | 9,414,795 | 627,651 | -8,787,144 | 3.06 | 3.90 | +0.83 | sell |