| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| PRICE T ROWE ASSOCIATES INC /MD/ | 3,870,547 | 4,940,907 | +1,070,360 | 0.00 | 0.00 | +0.00 | buy |
| CITADEL ADVISORS LLC | 830,610 | 983,785 | +153,175 | 0.00 | 0.01 | +0.00 | buy |
| Caption Management, LLC | 0 | 90,690 | +90,690 | 0.00 | 0.06 | +0.06 | buy |
| JANE STREET GROUP, LLC | 0 | 70,715 | +70,715 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 0 | 67,279 | +67,279 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 10,694 | 63,204 | +52,510 | 0.00 | 0.00 | +0.00 | buy |
| SPHERA FUNDS MANAGEMENT LTD. | 0 | 48,511 | +48,511 | 0.00 | 0.05 | +0.05 | buy |
| BARCLAYS PLC | 13,171 | 61,268 | +48,097 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0 | 46,387 | +46,387 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 647,488 | 687,671 | +40,183 | 0.00 | 0.00 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 38,802 | +38,802 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 0 | 28,861 | +28,861 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 0 | 17,462 | +17,462 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 23,309 | 37,948 | +14,639 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 91,500 | 105,200 | +13,700 | 0.00 | 0.00 | +0.00 | buy |
| Cubist Systematic Strategies, LLC | 0 | 10,602 | +10,602 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 0 | 10,518 | +10,518 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Middle East FZE | 0 | 9,290 | +9,290 | 0.00 | 0.00 | +0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 19,814 | 26,280 | +6,466 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 94,055 | 100,516 | +6,461 | 0.00 | 0.00 | +0.00 | buy |
| EXCHANGE TRADED CONCEPTS, LLC | 17,412 | 23,327 | +5,915 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 707 | 4,398 | +3,691 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 242,493 | 245,562 | +3,069 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 9,756 | 11,883 | +2,127 | 0.00 | 0.00 | +0.00 | buy |
| COMERICA BANK | 0 | 841 | +841 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 2,241 | 2,241 | 0 | 0.00 | 0.00 | +0.00 | hold |
| TD ASSET MANAGEMENT INC | 193,168 | 193,168 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CORNERCAP INVESTMENT COUNSEL INC | 27,844 | 27,844 | 0 | 0.02 | 0.03 | +0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 23,570 | 23,570 | 0 | 0.00 | 0.00 | +0.00 | hold |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 300 | 300 | 0 | 0.00 | 0.00 | +0.00 | hold |
| BAKER BROS. ADVISORS LP | 4,916,095 | 4,916,095 | 0 | 0.14 | 0.32 | +0.18 | hold |
| Sarasin & Partners LLP | 65,081 | 65,081 | 0 | 0.00 | 0.00 | +0.00 | hold |
| NEA Management Company, LLC | 7,692,298 | 7,692,298 | 0 | 2.85 | 2.90 | +0.05 | hold |
| MetLife Investment Management, LLC | 18,157 | 18,157 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Casdin Capital, LLC | 510,882 | 510,882 | 0 | 0.27 | 0.28 | +0.01 | hold |
| Candriam S.C.A. | 135,000 | 135,000 | 0 | 0.00 | 0.01 | +0.00 | hold |
| Avoro Capital Advisors LLC | 4,535,000 | 4,535,000 | 0 | 0.34 | 0.35 | +0.02 | hold |
| Alphabet Inc. | 1,464,015 | 1,464,015 | 0 | 0.45 | 0.38 | -0.07 | hold |
| Aisling Capital Management LP | 1,472,331 | 1,472,331 | 0 | 2.91 | 2.48 | -0.42 | hold |
| METROPOLITAN LIFE INSURANCE CO/NY | 1,820 | 1,820 | 0 | 0.00 | 0.00 | +0.00 | hold |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 104,543 | 104,543 | 0 | 0.00 | 0.00 | +0.00 | hold |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 14,950 | 14,950 | 0 | 0.00 | 0.00 | +0.00 | hold |
| DEUTSCHE BANK AG\ | 13,959 | 13,959 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AMERICAN INTERNATIONAL GROUP, INC. | 15,221 | 15,160 | -61 | 0.00 | 0.00 | -0.00 | sell |
| NEW YORK STATE COMMON RETIREMENT FUND | 12,225 | 12,164 | -61 | 0.00 | 0.00 | +0.00 | sell |
| Daiwa Securities Group Inc. | 136 | 0 | -136 | 0.00 | 0.00 | -0.00 | sell |
| RHUMBLINE ADVISERS | 45,603 | 45,360 | -243 | 0.00 | 0.00 | +0.00 | sell |
| AMALGAMATED BANK | 3,029 | 2,733 | -296 | 0.00 | 0.00 | -0.00 | sell |
| BANK OF AMERICA CORP /DE/ | 81,600 | 80,707 | -893 | 0.00 | 0.00 | +0.00 | sell |
| Mirae Asset Global Investments Co., Ltd. | 13,113 | 11,946 | -1,167 | 0.00 | 0.00 | -0.00 | sell |
| NISA INVESTMENT ADVISORS, LLC | 1,170 | 0 | -1,170 | 0.00 | 0.00 | -0.00 | sell |
| China Universal Asset Management Co., Ltd. | 1,280 | 0 | -1,280 | 0.00 | 0.00 | -0.00 | sell |
| SG Americas Securities, LLC | 13,866 | 12,257 | -1,609 | 0.00 | 0.00 | -0.00 | sell |
| JPMORGAN CHASE & CO | 29,454 | 22,036 | -7,418 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 17,163 | 7,796 | -9,367 | 0.00 | 0.00 | -0.00 | sell |
| STATE OF WISCONSIN INVESTMENT BOARD | 38,116 | 27,800 | -10,316 | 0.00 | 0.00 | -0.00 | sell |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 11,925 | 0 | -11,925 | 0.00 | 0.00 | -0.00 | sell |
| Arizona State Retirement System | 11,951 | 0 | -11,951 | 0.00 | 0.00 | -0.00 | sell |
| DIMENSIONAL FUND ADVISORS LP | 37,284 | 24,313 | -12,971 | 0.00 | 0.00 | -0.00 | sell |
| Verition Fund Management LLC | 13,127 | 0 | -13,127 | 0.00 | 0.00 | -0.00 | sell |
| Legal & General Group Plc | 34,625 | 20,168 | -14,457 | 0.00 | 0.00 | -0.00 | sell |
| Corton Capital Inc. | 14,460 | 0 | -14,460 | 0.03 | 0.00 | -0.03 | sell |
| Connor, Clark & Lunn Investment Management Ltd. | 14,655 | 0 | -14,655 | 0.00 | 0.00 | -0.00 | sell |
| SIMPLEX TRADING, LLC | 26,245 | 10,043 | -16,202 | 0.00 | 0.00 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 54,210 | 37,178 | -17,032 | 0.00 | 0.00 | -0.00 | sell |
| STATE STREET CORP | 592,758 | 573,409 | -19,349 | 0.00 | 0.00 | +0.00 | sell |
| JANUS HENDERSON GROUP PLC | 23,743 | 0 | -23,743 | 0.00 | 0.00 | -0.00 | sell |
| Trexquant Investment LP | 25,657 | 0 | -25,657 | 0.00 | 0.00 | -0.00 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 43,834 | 5,020 | -38,814 | 0.00 | 0.00 | -0.00 | sell |
| VANGUARD GROUP INC | 1,628,377 | 1,588,417 | -39,960 | 0.00 | 0.00 | +0.00 | sell |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 85,478 | 44,247 | -41,231 | 0.01 | 0.01 | +0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 66,750 | 0 | -66,750 | 0.00 | 0.00 | -0.00 | sell |
| VOYA INVESTMENT MANAGEMENT LLC | 92,830 | 12,465 | -80,365 | 0.00 | 0.00 | -0.00 | sell |
| Swiss National Bank | 91,300 | 0 | -91,300 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 443,962 | 284,934 | -159,028 | 0.00 | 0.00 | -0.00 | sell |
| ExodusPoint Capital Management, LP | 619,248 | 229,804 | -389,444 | 0.04 | 0.02 | -0.02 | sell |
| FMR LLC | 6,004,833 | 5,537,239 | -467,594 | 0.00 | 0.00 | -0.00 | sell |
| Octagon Capital Advisors LP | 812,895 | 0 | -812,895 | 0.69 | 0.00 | -0.69 | sell |