| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| RHUMBLINE ADVISERS | 0 | 125,457 | +125,457 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 0 | 14,621 | +14,621 | 0.00 | 0.00 | +0.00 | buy |
| FNY Investment Advisers, LLC | 0 | 13,800 | +13,800 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 346,000 | 0 | -346,000 | 0.00 | 0.00 | -0.00 | sell |
| VIKING GLOBAL INVESTORS LP | 3,564,173 | 0 | -3,564,173 | 0.06 | 0.00 | -0.06 | sell |
| TWO SIGMA INVESTMENTS, LP | 13,291 | 0 | -13,291 | 0.00 | 0.00 | -0.00 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 25,027 | 0 | -25,027 | 0.00 | 0.00 | -0.00 | sell |
| PERCEPTIVE ADVISORS LLC | 57,558,451 | 0 | -57,558,451 | 5.75 | 0.00 | -5.75 | sell |
| TANG CAPITAL MANAGEMENT LLC | 9,366,783 | 0 | -9,366,783 | 3.87 | 0.00 | -3.87 | sell |
| MILLENNIUM MANAGEMENT LLC | 42,074 | 0 | -42,074 | 0.00 | 0.00 | -0.00 | sell |
| Anson Funds Management LP | 117,146 | 0 | -117,146 | 0.10 | 0.00 | -0.10 | sell |
| Casdin Capital, LLC | 206,415 | 0 | -206,415 | 0.09 | 0.00 | -0.09 | sell |
| TYBOURNE CAPITAL MANAGEMENT (HK) LTD | 3,398,890 | 0 | -3,398,890 | 2.26 | 0.00 | -2.26 | sell |
| MYDA Advisors LLC | 100,000 | 0 | -100,000 | 0.19 | 0.00 | -0.19 | sell |
| Cubist Systematic Strategies, LLC | 19,179 | 0 | -19,179 | 0.00 | 0.00 | -0.00 | sell |
| Donald L. Hagan, LLC | 20,600 | 0 | -20,600 | 0.05 | 0.00 | -0.05 | sell |
| OSAIC HOLDINGS, INC. | 17,555 | 0 | -17,555 | 0.00 | 0.00 | -0.00 | sell |
| 22NW, LP | 2,211,678 | 0 | -2,211,678 | 6.44 | 0.00 | -6.44 | sell |
| Affinity Asset Advisors, LLC | 3,779,694 | 0 | -3,779,694 | 3.37 | 0.00 | -3.37 | sell |
| Old Well Partners, LLC | 32,200 | 0 | -32,200 | 0.13 | 0.00 | -0.13 | sell |
| HighMark Wealth Management LLC | 100 | 0 | -100 | 0.00 | 0.00 | -0.00 | sell |
| Vida Ventures Advisors, LLC | 2,282,084 | 0 | -2,282,084 | 12.14 | 0.00 | -12.14 | sell |
| AXXCESS WEALTH MANAGEMENT, LLC | 27,126 | 0 | -27,126 | 0.00 | 0.00 | -0.00 | sell |
| EntryPoint Capital, LLC | 46 | 0 | -46 | 0.00 | 0.00 | -0.00 | sell |
| COMMONWEALTH EQUITY SERVICES, LLC | 10,830 | 0 | -10,830 | 0.00 | 0.00 | -0.00 | sell |
| STIFEL FINANCIAL CORP | 18,500 | 0 | -18,500 | 0.00 | 0.00 | -0.00 | sell |
| Invesco Ltd. | 38,039 | 0 | -38,039 | 0.00 | 0.00 | -0.00 | sell |
| ACADIAN ASSET MANAGEMENT LLC | 14,605 | 0 | -14,605 | 0.00 | 0.00 | -0.00 | sell |