| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Paradigm Biocapital Advisors LP | 0 | 1,096,851 | +1,096,851 | 0.00 | 1.70 | +1.70 | buy |
| T. Rowe Price Investment Management, Inc. | 0 | 984,001 | +984,001 | 0.00 | 0.03 | +0.03 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 3,620,135 | 3,939,109 | +318,974 | 0.02 | 0.02 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 33,397 | 296,435 | +263,038 | 0.00 | 0.01 | +0.01 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 1,119,000 | 1,374,000 | +255,000 | 0.07 | 0.11 | +0.03 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 6,047 | 175,591 | +169,544 | 0.00 | 0.02 | +0.02 | buy |
| Holocene Advisors, LP | 1,796,077 | 1,954,528 | +158,451 | 0.27 | 0.35 | +0.08 | buy |
| Candriam S.C.A. | 293,760 | 450,992 | +157,232 | 0.06 | 0.11 | +0.05 | buy |
| DEUTSCHE BANK AG\ | 635,360 | 766,544 | +131,184 | 0.01 | 0.01 | +0.00 | buy |
| SAMLYN CAPITAL, LLC | 1,231,911 | 1,359,227 | +127,316 | 0.77 | 0.97 | +0.20 | buy |
| LORD, ABBETT & CO. LLC | 301,817 | 426,014 | +124,197 | 0.04 | 0.06 | +0.02 | buy |
| FEDERATED HERMES, INC. | 290,000 | 414,105 | +124,105 | 0.02 | 0.04 | +0.02 | buy |
| First Turn Management, LLC | 212,944 | 326,494 | +113,550 | 1.25 | 2.28 | +1.03 | buy |
| ExodusPoint Capital Management, LP | 41,917 | 153,596 | +111,679 | 0.02 | 0.07 | +0.05 | buy |
| Pier Capital, LLC | 0 | 103,463 | +103,463 | 0.00 | 0.64 | +0.64 | buy |
| Affinity Asset Advisors, LLC | 375,000 | 435,000 | +60,000 | 2.14 | 2.98 | +0.85 | buy |
| MARSHALL WACE, LLP | 524,578 | 583,725 | +59,147 | 0.03 | 0.03 | +0.01 | buy |
| EASTERN BANK | 0 | 56,050 | +56,050 | 0.00 | 0.04 | +0.04 | buy |
| VANGUARD GROUP INC | 2,524,176 | 2,580,177 | +56,001 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asset Management, L.P. | 119,000 | 171,573 | +52,573 | 0.01 | 0.03 | +0.01 | buy |
| Woodline Partners LP | 948,917 | 1,000,893 | +51,976 | 0.33 | 0.37 | +0.04 | buy |
| Trexquant Investment LP | 0 | 51,839 | +51,839 | 0.00 | 0.03 | +0.03 | buy |
| Cubist Systematic Strategies, LLC | 53,940 | 101,942 | +48,002 | 0.03 | 0.07 | +0.03 | buy |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 433,172 | 476,713 | +43,541 | 0.02 | 0.02 | +0.00 | buy |
| Verition Fund Management LLC | 0 | 43,210 | +43,210 | 0.00 | 0.01 | +0.01 | buy |
| BARCLAYS PLC | 44,001 | 85,395 | +41,394 | 0.00 | 0.00 | +0.00 | buy |
| TD ASSET MANAGEMENT INC | 154,338 | 192,894 | +38,556 | 0.01 | 0.01 | +0.00 | buy |
| MORGAN STANLEY | 305,438 | 341,076 | +35,638 | 0.00 | 0.00 | +0.00 | buy |
| Kynam Capital Management, LP | 1,543,669 | 1,576,549 | +32,880 | 5.85 | 5.40 | -0.45 | buy |
| THORNBURG INVESTMENT MANAGEMENT INC | 0 | 30,880 | +30,880 | 0.00 | 0.02 | +0.02 | buy |
| TUDOR INVESTMENT CORP ET AL | 0 | 24,478 | +24,478 | 0.00 | 0.01 | +0.01 | buy |
| Y-Intercept (Hong Kong) Ltd | 8,068 | 30,911 | +22,843 | 0.02 | 0.08 | +0.07 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 984,442 | 1,004,665 | +20,223 | 0.00 | 0.00 | +0.00 | buy |
| Crestline Management, LP | 63,550 | 81,315 | +17,765 | 0.18 | 0.20 | +0.02 | buy |
| Skandinaviska Enskilda Banken AB (publ) | 0 | 17,101 | +17,101 | 0.00 | 0.00 | +0.00 | buy |
| Harvest Investment Services, LLC | 0 | 16,313 | +16,313 | 0.00 | 0.23 | +0.23 | buy |
| Russell Investments Group, Ltd. | 10,531 | 25,265 | +14,734 | 0.00 | 0.00 | +0.00 | buy |
| EFG Asset Management (North America) Corp. | 31,444 | 45,968 | +14,524 | 0.20 | 0.34 | +0.14 | buy |
| Cinctive Capital Management LP | 34,772 | 48,500 | +13,728 | 0.07 | 0.12 | +0.06 | buy |
| Qube Research & Technologies Ltd | 0 | 13,376 | +13,376 | 0.00 | 0.00 | +0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 49,112 | 62,197 | +13,085 | 0.00 | 0.00 | +0.00 | buy |
| HighVista Strategies LLC | 9,162 | 22,010 | +12,848 | 0.12 | 0.34 | +0.21 | buy |
| Nicholas Investment Partners, LP | 59,129 | 71,559 | +12,430 | 0.22 | 0.29 | +0.07 | buy |
| Bayesian Capital Management, LP | 0 | 11,722 | +11,722 | 0.00 | 0.06 | +0.06 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 0 | 10,737 | +10,737 | 0.00 | 0.01 | +0.01 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 351,088 | 361,805 | +10,717 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 11,109 | 19,684 | +8,575 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 21,282 | 29,404 | +8,122 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 74,462 | 82,374 | +7,912 | 0.00 | 0.00 | +0.00 | buy |
| Brevan Howard Capital Management LP | 0 | 7,614 | +7,614 | 0.00 | 0.02 | +0.02 | buy |
| Eversept Partners, LP | 2,043,214 | 2,050,157 | +6,943 | 5.66 | 6.95 | +1.29 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 55,080 | 61,574 | +6,494 | 0.00 | 0.00 | +0.00 | buy |
| Westover Capital Advisors, LLC | 0 | 6,224 | +6,224 | 0.00 | 0.05 | +0.05 | buy |
| JENNISON ASSOCIATES LLC | 441,162 | 447,098 | +5,936 | 0.01 | 0.01 | +0.00 | buy |
| ALGERT GLOBAL LLC | 17,254 | 23,164 | +5,910 | 0.02 | 0.03 | +0.01 | buy |
| SG Americas Securities, LLC | 4,301 | 9,354 | +5,053 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asia (Singapore) Pte. Ltd. | 4,493 | 9,407 | +4,914 | 0.03 | 0.08 | +0.04 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 33,707 | 38,253 | +4,546 | 0.00 | 0.00 | +0.00 | buy |
| China Universal Asset Management Co., Ltd. | 6,427 | 10,545 | +4,118 | 0.03 | 0.05 | +0.02 | buy |
| STRS OHIO | 400 | 3,900 | +3,500 | 0.00 | 0.00 | +0.00 | buy |
| Point72 (DIFC) Ltd | 40,413 | 43,789 | +3,376 | 0.13 | 0.15 | +0.02 | buy |
| Rock Springs Capital Management LP | 381,192 | 383,492 | +2,300 | 0.42 | 0.55 | +0.14 | buy |
| Handelsbanken Fonder AB | 11,600 | 13,800 | +2,200 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 0 | 2,185 | +2,185 | 0.00 | 0.00 | +0.00 | buy |
| Allianz Asset Management GmbH | 15,300 | 17,200 | +1,900 | 0.00 | 0.00 | +0.00 | buy |
| ProShare Advisors LLC | 8,749 | 10,604 | +1,855 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 18,756 | 20,510 | +1,754 | 0.00 | 0.00 | +0.00 | buy |
| ALPS ADVISORS INC | 42,834 | 44,266 | +1,432 | 0.01 | 0.01 | +0.00 | buy |
| Catalyst Funds Management Pty Ltd | 0 | 1,200 | +1,200 | 0.00 | 0.01 | +0.01 | buy |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 7,761 | 8,918 | +1,157 | 0.00 | 0.00 | +0.00 | buy |
| PLATINUM INVESTMENT MANAGEMENT LTD | 136,416 | 137,389 | +973 | 0.20 | 0.27 | +0.08 | buy |
| ROYAL BANK OF CANADA | 4,583 | 5,321 | +738 | 0.00 | 0.00 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 1,633 | 1,983 | +350 | 0.00 | 0.00 | +0.00 | buy |
| Arizona State Retirement System | 9,907 | 10,238 | +331 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 39,373 | 39,496 | +123 | 0.00 | 0.00 | +0.00 | buy |
| GAMMA Investing LLC | 247 | 361 | +114 | 0.00 | 0.00 | +0.00 | buy |
| AXA S.A. | 246,201 | 246,269 | +68 | 0.03 | 0.03 | +0.01 | buy |
| NISA INVESTMENT ADVISORS, LLC | 67 | 121 | +54 | 0.00 | 0.00 | +0.00 | buy |
| VIRTUS ADVISERS, LLC | 2,420 | 2,465 | +45 | 0.04 | 0.05 | +0.01 | buy |
| BESSEMER GROUP INC | 0 | 35 | +35 | 0.00 | 0.00 | +0.00 | buy |
| ROTHSCHILD INVESTMENT LLC | 15 | 40 | +25 | 0.00 | 0.00 | +0.00 | buy |
| Federation des caisses Desjardins du Quebec | 0 | 20 | +20 | 0.00 | 0.00 | +0.00 | buy |
| Parallel Advisors, LLC | 0 | 15 | +15 | 0.00 | 0.00 | +0.00 | buy |
| Fortitude Family Office, LLC | 0 | 14 | +14 | 0.00 | 0.00 | +0.00 | buy |
| EARNED WEALTH ADVISORS, LLC | 0 | 11 | +11 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 10 | 14 | +4 | 0.00 | 0.00 | +0.00 | buy |
| WEXFORD CAPITAL LP | 46,855 | 46,855 | 0 | 0.43 | 0.50 | +0.07 | hold |
| ORBIMED ADVISORS LLC | 675,872 | 675,872 | 0 | 0.49 | 0.55 | +0.06 | hold |
| NOMURA ASSET MANAGEMENT CO LTD | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| Ameritas Investment Partners, Inc. | 4,000 | 4,000 | 0 | 0.00 | 0.01 | +0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 39,550 | 39,550 | 0 | 0.00 | 0.00 | +0.00 | hold |
| JANUS HENDERSON GROUP PLC | 14,500 | 14,500 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 7,527 | 7,527 | 0 | 0.00 | 0.00 | +0.00 | hold |
| HALL LAURIE J TRUSTEE | 600 | 600 | 0 | 0.01 | 0.01 | +0.00 | hold |
| KBC Group NV | 1,090 | 1,090 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Jasper Ridge Partners, L.P. | 15,639 | 15,639 | 0 | 0.02 | 0.02 | +0.00 | hold |
| Ensign Peak Advisors, Inc | 11,750 | 11,750 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Daiwa Securities Group Inc. | 182 | 182 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MetLife Investment Management, LLC | 22,778 | 22,778 | 0 | 0.00 | 0.01 | +0.00 | hold |
| Swiss National Bank | 69,700 | 69,700 | 0 | 0.00 | 0.00 | +0.00 | hold |