| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Deep Track Capital, LP | 0 | 2,821,135 | +2,821,135 | 0.00 | 3.26 | +3.26 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 3,666,439 | 5,461,976 | +1,795,537 | 0.01 | 0.03 | +0.02 | buy |
| Bellevue Group AG | 0 | 1,698,152 | +1,698,152 | 0.00 | 1.63 | +1.63 | buy |
| Holocene Advisors, LP | 0 | 1,307,393 | +1,307,393 | 0.00 | 0.14 | +0.14 | buy |
| ALLIANCEBERNSTEIN L.P. | 52,591 | 1,218,657 | +1,166,066 | 0.00 | 0.02 | +0.02 | buy |
| BlackRock, Inc. | 4,247,190 | 4,825,519 | +578,329 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asset Management, L.P. | 1,272,027 | 1,738,385 | +466,358 | 0.08 | 0.14 | +0.06 | buy |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 3,641,157 | 4,059,695 | +418,538 | 1.62 | 2.64 | +1.01 | buy |
| VANGUARD GROUP INC | 3,190,653 | 3,570,401 | +379,748 | 0.00 | 0.00 | +0.00 | buy |
| FRONTIER CAPITAL MANAGEMENT CO LLC | 0 | 371,151 | +371,151 | 0.00 | 0.20 | +0.20 | buy |
| First Light Asset Management, LLC | 507,097 | 869,676 | +362,579 | 1.39 | 3.37 | +1.98 | buy |
| GOLDMAN SACHS GROUP INC | 758,566 | 1,120,780 | +362,214 | 0.00 | 0.01 | +0.00 | buy |
| ORBIMED ADVISORS LLC | 0 | 353,500 | +353,500 | 0.00 | 0.37 | +0.37 | buy |
| STATE STREET CORP | 2,333,583 | 2,676,600 | +343,017 | 0.00 | 0.00 | +0.00 | buy |
| BRAIDWELL LP | 472,739 | 784,742 | +312,003 | 0.41 | 1.27 | +0.86 | buy |
| Rhenman & Partners Asset Management AB | 130,000 | 420,000 | +290,000 | 0.42 | 1.99 | +1.57 | buy |
| Eversept Partners, LP | 2,807,836 | 3,072,304 | +264,468 | 6.25 | 8.72 | +2.47 | buy |
| Woodline Partners LP | 737,578 | 1,000,279 | +262,701 | 0.10 | 0.20 | +0.10 | buy |
| TimesSquare Capital Management, LLC | 0 | 252,462 | +252,462 | 0.00 | 0.19 | +0.19 | buy |
| First Turn Management, LLC | 354,529 | 601,774 | +247,245 | 1.55 | 3.48 | +1.93 | buy |
| MORGAN STANLEY | 274,523 | 499,665 | +225,142 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 253,976 | 474,668 | +220,692 | 0.01 | 0.02 | +0.01 | buy |
| BANK OF AMERICA CORP /DE/ | 490,472 | 694,319 | +203,847 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 193,400 | +193,400 | 0.00 | 0.02 | +0.02 | buy |
| CITIGROUP INC | 9,134 | 174,255 | +165,121 | 0.00 | 0.01 | +0.01 | buy |
| BNP Paribas Asset Management Holding S.A. | 416 | 154,553 | +154,137 | 0.00 | 0.01 | +0.01 | buy |
| Nicholas Investment Partners, LP | 0 | 144,810 | +144,810 | 0.00 | 0.53 | +0.53 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,321,575 | 1,444,925 | +123,350 | 0.00 | 0.00 | +0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 82,282 | 202,953 | +120,671 | 0.00 | 0.00 | +0.00 | buy |
| ARMISTICE CAPITAL, LLC | 536,000 | 653,796 | +117,796 | 0.49 | 0.81 | +0.32 | buy |
| TD ASSET MANAGEMENT INC | 210,474 | 325,564 | +115,090 | 0.00 | 0.01 | +0.01 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 66,607 | 176,684 | +110,077 | 0.00 | 0.01 | +0.01 | buy |
| Integral Health Asset Management, LLC | 1,700,000 | 1,800,000 | +100,000 | 3.60 | 4.62 | +1.02 | buy |
| ExodusPoint Capital Management, LP | 0 | 72,741 | +72,741 | 0.00 | 0.04 | +0.04 | buy |
| Swedbank AB | 50,000 | 121,200 | +71,200 | 0.00 | 0.01 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 139,585 | 207,968 | +68,383 | 0.00 | 0.01 | +0.01 | buy |
| WELLS FARGO & COMPANY/MN | 81,212 | 145,205 | +63,993 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 30,632 | 89,851 | +59,219 | 0.00 | 0.00 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 54,327 | +54,327 | 0.00 | 0.01 | +0.01 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 465,809 | 518,858 | +53,049 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 162,075 | 207,289 | +45,214 | 0.00 | 0.00 | +0.00 | buy |
| Birchview Capital, LP | 0 | 44,000 | +44,000 | 0.00 | 1.30 | +1.30 | buy |
| FMR LLC | 2,843,131 | 2,885,853 | +42,722 | 0.00 | 0.01 | +0.00 | buy |
| E. Ohman J:or Asset Management AB | 0 | 39,500 | +39,500 | 0.00 | 0.05 | +0.05 | buy |
| TWO SIGMA INVESTMENTS, LP | 171,659 | 209,951 | +38,292 | 0.01 | 0.02 | +0.01 | buy |
| GW&K Investment Management, LLC | 77,065 | 113,753 | +36,688 | 0.02 | 0.05 | +0.03 | buy |
| BARCLAYS PLC | 217,593 | 253,716 | +36,123 | 0.00 | 0.01 | +0.00 | buy |
| Headlands Technologies LLC | 7,993 | 42,825 | +34,832 | 0.02 | 0.18 | +0.16 | buy |
| Man Group plc | 0 | 32,364 | +32,364 | 0.00 | 0.00 | +0.00 | buy |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0 | 28,323 | +28,323 | 0.00 | 0.00 | +0.00 | buy |
| COMERICA BANK | 124 | 27,731 | +27,607 | 0.00 | 0.01 | +0.01 | buy |
| Neo Ivy Capital Management | 0 | 25,452 | +25,452 | 0.00 | 0.20 | +0.20 | buy |
| Burkehill Global Management, LP | 0 | 25,000 | +25,000 | 0.00 | 0.08 | +0.08 | buy |
| AMERICAN CENTURY COMPANIES INC | 708,423 | 732,699 | +24,276 | 0.01 | 0.02 | +0.01 | buy |
| Monashee Investment Management LLC | 0 | 22,905 | +22,905 | 0.00 | 0.65 | +0.65 | buy |
| Candriam S.C.A. | 427,189 | 449,554 | +22,365 | 0.06 | 0.11 | +0.05 | buy |
| ALPS ADVISORS INC | 30,750 | 52,392 | +21,642 | 0.00 | 0.02 | +0.01 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 17,929 | 38,021 | +20,092 | 0.00 | 0.00 | +0.00 | buy |
| Laurion Capital Management LP | 0 | 20,000 | +20,000 | 0.00 | 0.07 | +0.07 | buy |
| TWINBEECH CAPITAL LP | 0 | 18,930 | +18,930 | 0.00 | 0.07 | +0.07 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 102,200 | 120,600 | +18,400 | 0.00 | 0.00 | +0.00 | buy |
| FOX RUN MANAGEMENT, L.L.C. | 0 | 17,033 | +17,033 | 0.00 | 0.13 | +0.13 | buy |
| CenterBook Partners LP | 0 | 15,639 | +15,639 | 0.00 | 0.04 | +0.04 | buy |
| Quantinno Capital Management LP | 0 | 14,855 | +14,855 | 0.00 | 0.00 | +0.00 | buy |
| ADAR1 Capital Management, LLC | 0 | 14,733 | +14,733 | 0.00 | 0.06 | +0.06 | buy |
| State of New Jersey Common Pension Fund D | 0 | 13,071 | +13,071 | 0.00 | 0.00 | +0.00 | buy |
| PROFUND ADVISORS LLC | 18,992 | 32,024 | +13,032 | 0.02 | 0.05 | +0.03 | buy |
| NORTHERN TRUST CORP | 461,260 | 473,219 | +11,959 | 0.00 | 0.00 | +0.00 | buy |
| Hennion & Walsh Asset Management, Inc. | 32,286 | 42,374 | +10,088 | 0.03 | 0.07 | +0.04 | buy |
| XTX Topco Ltd | 0 | 10,025 | +10,025 | 0.00 | 0.01 | +0.01 | buy |
| Creative Planning | 0 | 9,321 | +9,321 | 0.00 | 0.00 | +0.00 | buy |
| Allianz Asset Management GmbH | 0 | 8,700 | +8,700 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 161,541 | 169,734 | +8,193 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 0 | 7,906 | +7,906 | 0.00 | 0.00 | +0.00 | buy |
| Mariner, LLC | 0 | 7,789 | +7,789 | 0.00 | 0.00 | +0.00 | buy |
| Jain Global LLC | 0 | 7,133 | +7,133 | 0.00 | 0.00 | +0.00 | buy |
| SECTORAL ASSET MANAGEMENT INC | 30,188 | 36,858 | +6,670 | 0.54 | 1.50 | +0.95 | buy |
| RAYMOND JAMES FINANCIAL INC | 58,505 | 64,875 | +6,370 | 0.00 | 0.00 | +0.00 | buy |
| COMMONWEALTH EQUITY SERVICES, LLC | 0 | 6,141 | +6,141 | 0.00 | 0.00 | +0.00 | buy |
| SEI INVESTMENTS CO | 0 | 6,069 | +6,069 | 0.00 | 0.00 | +0.00 | buy |
| Quantbot Technologies LP | 0 | 5,909 | +5,909 | 0.00 | 0.01 | +0.01 | buy |
| Virtu Financial LLC | 0 | 5,870 | +5,870 | 0.00 | 0.01 | +0.01 | buy |
| Berkshire Money Management, Inc. | 0 | 5,000 | +5,000 | 0.00 | 0.02 | +0.02 | buy |
| FIDUCIARY TRUST CO | 0 | 4,902 | +4,902 | 0.00 | 0.00 | +0.00 | buy |
| Voleon Capital Management LP | 0 | 4,847 | +4,847 | 0.00 | 0.01 | +0.01 | buy |
| XPONANCE, INC. | 0 | 4,359 | +4,359 | 0.00 | 0.00 | +0.00 | buy |
| Argentarii, LLC | 0 | 4,330 | +4,330 | 0.00 | 0.07 | +0.07 | buy |
| Scientech Research LLC | 0 | 4,286 | +4,286 | 0.00 | 0.14 | +0.14 | buy |
| FORA Capital, LLC | 0 | 4,074 | +4,074 | 0.00 | 0.02 | +0.02 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 0 | 3,959 | +3,959 | 0.00 | 0.00 | +0.00 | buy |
| Parkman Healthcare Partners LLC | 96,737 | 100,564 | +3,827 | 0.31 | 0.48 | +0.18 | buy |
| Walleye Capital LLC | 12,051 | 14,926 | +2,875 | 0.00 | 0.00 | +0.00 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 416,376 | 418,963 | +2,587 | 0.01 | 0.02 | +0.01 | buy |
| Sandia Investment Management LP | 0 | 2,500 | +2,500 | 0.00 | 0.32 | +0.32 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 28,383 | 30,797 | +2,414 | 0.00 | 0.00 | +0.00 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 16,233 | 18,624 | +2,391 | 0.00 | 0.00 | +0.00 | buy |
| ProShare Advisors LLC | 11,074 | 12,938 | +1,864 | 0.00 | 0.00 | +0.00 | buy |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 10,120 | 11,900 | +1,780 | 0.00 | 0.00 | +0.00 | buy |
| Perigon Wealth Management, LLC | 12,898 | 14,396 | +1,498 | 0.01 | 0.01 | +0.01 | buy |
| Aster Capital Management (DIFC) Ltd | 0 | 1,406 | +1,406 | 0.00 | 0.03 | +0.03 | buy |