| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| WELLINGTON MANAGEMENT GROUP LLP | 14,070,893 | 17,098,936 | +3,028,043 | 0.05 | 0.06 | +0.01 | buy |
| FMR LLC | 14,655,935 | 15,892,064 | +1,236,129 | 0.01 | 0.01 | -0.00 | buy |
| BlackRock, Inc. | 13,711,314 | 14,075,197 | +363,883 | 0.00 | 0.00 | -0.00 | buy |
| T. Rowe Price Investment Management, Inc. | 12,643,784 | 13,147,656 | +503,872 | 0.16 | 0.16 | +0.00 | buy |
| Invesco Ltd. | 6,202,592 | 7,000,099 | +797,507 | 0.02 | 0.02 | +0.00 | buy |
| Hood River Capital Management LLC | 6,173,433 | 6,054,477 | -118,956 | 1.34 | 1.07 | -0.27 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 5,466,117 | 5,741,306 | +275,189 | 0.01 | 0.01 | +0.00 | buy |
| CITADEL ADVISORS LLC | 4,340,866 | 5,362,666 | +1,021,800 | 0.06 | 0.07 | +0.01 | buy |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 2,305,255 | 5,214,614 | +2,909,359 | 0.13 | 0.30 | +0.18 | buy |
| PICTON MAHONEY ASSET MANAGEMENT | 0 | 5,000,000 | +5,000,000 | 0.00 | 0.07 | +0.07 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 3,841,703 | 4,411,340 | +569,637 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 3,668,602 | 4,293,694 | +625,092 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 2,567,066 | 3,838,020 | +1,270,954 | 0.04 | 0.05 | +0.01 | buy |
| Capital Research Global Investors | 0 | 3,593,576 | +3,593,576 | 0.00 | 0.01 | +0.01 | buy |
| Bank of New York Mellon Corp | 996,333 | 3,313,110 | +2,316,777 | 0.00 | 0.01 | +0.01 | buy |
| BANK OF AMERICA CORP /DE/ | 1,253,889 | 3,215,667 | +1,961,778 | 0.00 | 0.00 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 3,000,000 | +3,000,000 | 0.00 | 0.01 | +0.01 | buy |
| Broad Bay Capital Management, LP | 2,510,760 | 2,919,465 | +408,705 | 5.66 | 5.29 | -0.38 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 2,667,200 | 2,903,100 | +235,900 | 0.08 | 0.08 | -0.00 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 3,672,439 | 2,795,706 | -876,733 | 0.07 | 0.05 | -0.02 | sell |
| Capital World Investors | 2,238,147 | 2,666,058 | +427,911 | 0.01 | 0.01 | +0.00 | buy |
| Integral Health Asset Management, LLC | 2,200,000 | 2,575,000 | +375,000 | 2.20 | 2.40 | +0.20 | buy |
| Allspring Global Investments Holdings, LLC | 652,648 | 2,458,400 | +1,805,752 | 0.02 | 0.07 | +0.05 | buy |
| Point72 Asset Management, L.P. | 2,041,856 | 2,439,637 | +397,781 | 0.06 | 0.07 | +0.01 | buy |
| NEXT CENTURY GROWTH INVESTORS LLC | 2,308,287 | 2,262,076 | -46,211 | 3.17 | 2.89 | -0.28 | sell |
| LOOMIS SAYLES & CO L P | 2,236,058 | 2,106,068 | -129,990 | 0.05 | 0.05 | -0.00 | sell |
| AMERIPRISE FINANCIAL INC | 1,927,916 | 2,101,456 | +173,540 | 0.01 | 0.01 | -0.00 | buy |
| GILDER GAGNON HOWE & CO LLC | 1,857,139 | 1,833,691 | -23,448 | 0.39 | 0.39 | +0.00 | sell |
| NORTHERN TRUST CORP | 1,383,301 | 1,583,617 | +200,316 | 0.00 | 0.00 | +0.00 | buy |
| Nuveen, LLC | 2,137,007 | 1,580,582 | -556,425 | 0.01 | 0.01 | -0.00 | sell |
| MORGAN STANLEY | 2,362,546 | 1,526,839 | -835,707 | 0.00 | 0.00 | -0.00 | sell |
| Qube Research & Technologies Ltd | 1,513,852 | 1,517,992 | +4,140 | 0.04 | 0.04 | -0.00 | buy |
| SSI INVESTMENT MANAGEMENT LLC | 0 | 1,500,000 | +1,500,000 | 0.00 | 0.15 | +0.15 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,276,344 | 1,401,658 | +125,314 | 0.00 | 0.00 | -0.00 | buy |
| Freestone Grove Partners LP | 620,210 | 1,337,777 | +717,567 | 0.09 | 0.17 | +0.08 | buy |
| Rhenman & Partners Asset Management AB | 1,009,450 | 1,053,450 | +44,000 | 1.86 | 2.29 | +0.43 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 135,771 | 1,050,174 | +914,403 | 0.00 | 0.03 | +0.02 | buy |
| GOLDMAN SACHS GROUP INC | 1,152,419 | 1,011,650 | -140,769 | 0.00 | 0.00 | -0.00 | sell |
| OBERWEIS ASSET MANAGEMENT INC/ | 747,500 | 966,600 | +219,100 | 0.54 | 0.50 | -0.04 | buy |
| JUPITER ASSET MANAGEMENT LTD | 765,233 | 877,769 | +112,536 | 0.12 | 0.08 | -0.04 | buy |
| AQR CAPITAL MANAGEMENT LLC | 885,004 | 817,266 | -67,738 | 0.01 | 0.01 | -0.00 | sell |
| ORBIMED ADVISORS LLC | 0 | 791,000 | +791,000 | 0.00 | 0.30 | +0.30 | buy |
| Granahan Investment Management, LLC | 749,487 | 780,500 | +31,013 | 0.63 | 0.67 | +0.03 | buy |
| MARSICO CAPITAL MANAGEMENT LLC | 713,341 | 779,767 | +66,426 | 0.39 | 0.40 | +0.01 | buy |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 1,705,040 | 759,957 | -945,083 | 0.02 | 0.01 | -0.01 | sell |
| SEI INVESTMENTS CO | 443,429 | 739,063 | +295,634 | 0.01 | 0.01 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 1,035,739 | 692,604 | -343,135 | 0.03 | 0.02 | -0.02 | sell |
| FIRST TRUST ADVISORS LP | 621,407 | 626,234 | +4,827 | 0.01 | 0.01 | -0.00 | buy |
| FEDERATED HERMES, INC. | 571,468 | 604,792 | +33,324 | 0.02 | 0.02 | -0.00 | buy |
| ROYCE & ASSOCIATES LP | 522,460 | 557,938 | +35,478 | 0.10 | 0.10 | -0.01 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 23,821 | 551,319 | +527,498 | 0.00 | 0.00 | +0.00 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 398,783 | 544,274 | +145,491 | 0.00 | 0.01 | +0.00 | buy |
| TD ASSET MANAGEMENT INC | 550,966 | 541,168 | -9,798 | 0.01 | 0.01 | -0.00 | sell |
| Pier Capital, LLC | 546,674 | 537,050 | -9,624 | 1.72 | 1.56 | -0.16 | sell |
| HENNESSY ADVISORS INC | 488,000 | 471,600 | -16,400 | 0.34 | 0.30 | -0.04 | sell |
| TWO SIGMA INVESTMENTS, LP | 316,727 | 465,127 | +148,400 | 0.01 | 0.01 | -0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 415,654 | 450,528 | +34,874 | 0.00 | 0.00 | -0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 482,714 | 445,818 | -36,896 | 0.00 | 0.00 | -0.00 | sell |
| Aberdeen Group plc | 0 | 413,043 | +413,043 | 0.00 | 0.01 | +0.01 | buy |
| PICTON MAHONEY ASSET MANAGEMENT | 404,156 | 401,849 | -2,307 | 0.09 | 0.07 | -0.01 | sell |
| PFM Health Sciences, LP | 0 | 359,826 | +359,826 | 0.00 | 0.67 | +0.67 | buy |
| Burkehill Global Management, LP | 350,000 | 350,000 | 0 | 0.46 | 0.31 | -0.15 | hold |
| OSTERWEIS CAPITAL MANAGEMENT INC | 0 | 346,985 | +346,985 | 0.00 | 0.32 | +0.32 | buy |
| PRUDENTIAL FINANCIAL INC | 487,650 | 336,980 | -150,670 | 0.01 | 0.01 | -0.00 | sell |
| Swiss National Bank | 331,900 | 331,900 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BNP Paribas Asset Management Holding S.A. | 246,851 | 327,009 | +80,158 | 0.01 | 0.01 | +0.00 | buy |
| 1492 Capital Management LLC | 324,865 | 324,019 | -846 | 2.46 | 2.17 | -0.28 | sell |
| AMERICAN CENTURY COMPANIES INC | 41,575 | 312,851 | +271,276 | 0.00 | 0.00 | +0.00 | buy |
| PANAGORA ASSET MANAGEMENT INC | 295,594 | 295,594 | 0 | 0.02 | 0.02 | -0.00 | hold |
| Edgestream Partners, L.P. | 0 | 275,393 | +275,393 | 0.00 | 0.16 | +0.16 | buy |
| LGT Fund Management Co Ltd. | 287,000 | 272,700 | -14,300 | 0.44 | 0.21 | -0.23 | sell |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 342,716 | 267,147 | -75,569 | 0.00 | 0.00 | -0.00 | sell |
| FORMULA GROWTH LTD | 239,508 | 239,208 | -300 | 1.82 | 1.90 | +0.08 | sell |
| CITIGROUP INC | 150,423 | 237,947 | +87,524 | 0.00 | 0.00 | +0.00 | buy |
| MARSHALL WACE, LLP | 17,131 | 237,656 | +220,525 | 0.00 | 0.00 | +0.00 | buy |
| Maven Securities LTD | 110,000 | 236,721 | +126,721 | 0.28 | 0.24 | -0.03 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 192,029 | 232,076 | +40,047 | 0.01 | 0.01 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 214,553 | 229,453 | +14,900 | 0.01 | 0.01 | -0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 224,834 | 224,380 | -454 | 0.00 | 0.00 | -0.00 | sell |
| Voleon Capital Management LP | 448,963 | 220,818 | -228,145 | 0.19 | 0.08 | -0.11 | sell |
| RHUMBLINE ADVISERS | 198,730 | 218,505 | +19,775 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 247,726 | 217,182 | -30,544 | 0.01 | 0.01 | -0.00 | sell |
| TUDOR INVESTMENT CORP ET AL | 0 | 212,489 | +212,489 | 0.00 | 0.02 | +0.02 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 158,065 | 198,200 | +40,135 | 0.00 | 0.00 | +0.00 | buy |
| Simplify Asset Management Inc. | 262,880 | 193,032 | -69,848 | 0.09 | 0.05 | -0.03 | sell |
| JPMORGAN CHASE & CO | 124,983 | 188,534 | +63,551 | 0.00 | 0.00 | +0.00 | buy |
| NORDEA INVESTMENT MANAGEMENT AB | 0 | 174,983 | +174,983 | 0.00 | 0.00 | +0.00 | buy |
| Hillsdale Investment Management Inc. | 156,270 | 173,870 | +17,600 | 0.09 | 0.08 | -0.00 | buy |
| DEUTSCHE BANK AG\ | 139,297 | 173,659 | +34,362 | 0.00 | 0.00 | +0.00 | buy |
| Baird Financial Group, Inc. | 184,396 | 171,014 | -13,382 | 0.01 | 0.00 | -0.00 | sell |
| Legal & General Group Plc | 179,088 | 154,517 | -24,571 | 0.00 | 0.00 | -0.00 | sell |
| Jain Global LLC | 111,989 | 152,922 | +40,933 | 0.02 | 0.03 | +0.01 | buy |
| Assenagon Asset Management S.A. | 1,774,975 | 152,846 | -1,622,129 | 0.05 | 0.00 | -0.05 | sell |
| SEVEN GRAND MANAGERS, LLC | 0 | 150,000 | +150,000 | 0.00 | 0.18 | +0.18 | buy |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 47,432 | 149,892 | +102,460 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 404,032 | 149,514 | -254,518 | 0.00 | 0.00 | -0.00 | sell |
| RAYMOND JAMES FINANCIAL INC | 101,288 | 149,038 | +47,750 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 146,064 | 139,723 | -6,341 | 0.00 | 0.00 | -0.00 | sell |
| ROYAL BANK OF CANADA | 150,260 | 136,886 | -13,374 | 0.00 | 0.00 | -0.00 | sell |
| Lisanti Capital Growth, LLC | 0 | 130,280 | +130,280 | 0.00 | 0.58 | +0.58 | buy |