| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 0 | 58,139,535 | +58,139,535 | 0.00 | 0.31 | +0.31 | buy |
| Deep Track Capital, LP | 0 | 58,139,535 | +58,139,535 | 0.00 | 0.69 | +0.69 | buy |
| Logos Global Management LP | 0 | 40,000,000 | +40,000,000 | 0.00 | 1.74 | +1.74 | buy |
| Avidity Partners Management LP | 0 | 34,884,000 | +34,884,000 | 0.00 | 0.51 | +0.51 | buy |
| SPHERA FUNDS MANAGEMENT LTD. | 0 | 25,581,395 | +25,581,395 | 0.00 | 1.71 | +1.71 | buy |
| Octagon Capital Advisors LP | 0 | 18,604,650 | +18,604,650 | 0.00 | 0.94 | +0.94 | buy |
| Rosalind Advisors, Inc. | 0 | 13,960,000 | +13,960,000 | 0.00 | 5.40 | +5.40 | buy |
| Altium Capital Management LLC | 0 | 13,953,488 | +13,953,488 | 0.00 | 2.58 | +2.58 | buy |
| Ikarian Capital, LLC | 0 | 13,953,488 | +13,953,488 | 0.00 | 1.57 | +1.57 | buy |
| Point72 Asset Management, L.P. | 30,061,112 | 13,664,080 | -16,397,032 | 0.04 | 0.02 | -0.02 | sell |
| Alyeska Investment Group, L.P. | 5,683,196 | 5,404,861 | -278,335 | 0.02 | 0.01 | -0.00 | sell |
| AIGH Capital Management LLC | 0 | 4,651,165 | +4,651,165 | 0.00 | 0.89 | +0.89 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 0 | 4,220,899 | +4,220,899 | 0.00 | 0.05 | +0.05 | buy |
| AWM Investment Company, Inc. | 0 | 2,250,000 | +2,250,000 | 0.00 | 0.12 | +0.12 | buy |
| AdvisorShares Investments LLC | 1,859,181 | 1,644,814 | -214,367 | 0.18 | 0.11 | -0.06 | sell |
| PDS Planning, Inc | 1,153,120 | 1,153,120 | 0 | 0.05 | 0.05 | -0.00 | hold |
| Propel Bio Management, LLC | 850,000 | 850,000 | 0 | 0.29 | 0.20 | -0.08 | hold |
| Simplify Asset Management Inc. | 500,000 | 500,000 | 0 | 0.03 | 0.02 | -0.01 | hold |
| FNY Investment Advisers, LLC | 402,000 | 310,999 | -91,001 | 0.18 | 0.08 | -0.11 | sell |
| Lewis Asset Management, LLC | 282,000 | 282,000 | 0 | 0.11 | 0.10 | -0.01 | hold |
| STIFEL FINANCIAL CORP | 0 | 243,724 | +243,724 | 0.00 | 0.00 | +0.00 | buy |
| Formidable Asset Management, LLC | 102,350 | 114,250 | +11,900 | 0.01 | 0.01 | -0.00 | buy |
| MONETA GROUP INVESTMENT ADVISORS LLC | 48,746 | 113,900 | +65,154 | 0.00 | 0.00 | +0.00 | buy |
| TD Waterhouse Canada Inc. | 43,333 | 109,999 | +66,666 | 0.00 | 0.00 | +0.00 | buy |
| IAG Wealth Partners, LLC | 104,513 | 104,513 | 0 | 0.01 | 0.01 | -0.00 | hold |
| Corient Private Wealth LLC | 0 | 100,000 | +100,000 | 0.00 | 0.00 | +0.00 | buy |
| Nadler Financial Group, Inc. | 43,700 | 98,700 | +55,000 | 0.00 | 0.01 | +0.00 | buy |
| HighTower Advisors, LLC | 48,599 | 96,183 | +47,584 | 0.00 | 0.00 | +0.00 | buy |
| CHANNEL WEALTH LLC | 0 | 90,000 | +90,000 | 0.00 | 0.01 | +0.01 | buy |
| Cerity Partners LLC | 88,271 | 84,271 | -4,000 | 0.00 | 0.00 | -0.00 | sell |
| Thrive Wealth Management, LLC | 128,000 | 82,700 | -45,300 | 0.01 | 0.01 | -0.00 | sell |
| RWA WEALTH PARTNERS, LLC | 58,647 | 75,617 | +16,970 | 0.00 | 0.00 | +0.00 | buy |
| WEDBUSH SECURITIES INC | 66,500 | 66,500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Rathbones Group PLC | 65,381 | 65,381 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Powell Investment Advisors, LLC | 60,000 | 60,000 | 0 | 0.01 | 0.01 | -0.00 | hold |
| North Star Investment Management Corp. | 52,000 | 52,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| YHB Investment Advisors, Inc. | 0 | 50,000 | +50,000 | 0.00 | 0.00 | +0.00 | buy |
| Integrated Wealth Concepts LLC | 0 | 47,075 | +47,075 | 0.00 | 0.00 | +0.00 | buy |
| LPL Financial LLC | 46,035 | 46,230 | +195 | 0.00 | 0.00 | -0.00 | buy |
| COMMONWEALTH EQUITY SERVICES, LLC | 35,839 | 44,598 | +8,759 | 0.00 | 0.00 | +0.00 | buy |
| X-Square Capital, LLC | 42,000 | 42,000 | 0 | 0.01 | 0.01 | -0.00 | hold |
| CRA Financial Services, LLC | 10,568 | 39,760 | +29,192 | 0.00 | 0.00 | +0.00 | buy |
| Strategic Blueprint, LLC | 32,000 | 38,000 | +6,000 | 0.00 | 0.00 | +0.00 | buy |
| Crewe Advisors LLC | 36,363 | 36,363 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BANK OF MONTREAL /CAN/ | 35,800 | 35,800 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CARDIFF PARK ADVISORS, LLC | 35,000 | 35,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Conservest Capital Advisors, Inc. | 40,100 | 33,500 | -6,600 | 0.00 | 0.00 | -0.00 | sell |
| HRT FINANCIAL LP | 24,047 | 29,684 | +5,637 | 0.00 | 0.00 | +0.00 | buy |
| MERCER GLOBAL ADVISORS INC /ADV | 23,000 | 29,000 | +6,000 | 0.00 | 0.00 | +0.00 | buy |
| EVOKE WEALTH, LLC | 25,000 | 25,000 | 0 | 0.02 | 0.00 | -0.02 | hold |
| Legacy Financial Group LLC | 0 | 22,666 | +22,666 | 0.00 | 0.00 | +0.00 | buy |
| Riverwater Partners LLC | 0 | 20,190 | +20,190 | 0.00 | 0.01 | +0.01 | buy |
| Jump Financial, LLC | 10,123 | 18,715 | +8,592 | 0.00 | 0.00 | +0.00 | buy |
| Creative Planning | 26,012 | 17,251 | -8,761 | 0.00 | 0.00 | -0.00 | sell |
| Balboa Wealth Partners | 17,108 | 17,108 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BOS Asset Management, LLC | 15,555 | 15,555 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SILVERLAKE WEALTH MANAGEMENT LLC | 0 | 15,000 | +15,000 | 0.00 | 0.00 | +0.00 | buy |
| INSIGNEO ADVISORY SERVICES, LLC | 0 | 14,285 | +14,285 | 0.00 | 0.00 | +0.00 | buy |
| Mariner, LLC | 13,650 | 13,650 | 0 | 0.00 | 0.00 | -0.00 | hold |
| EP Wealth Advisors, LLC | 0 | 12,000 | +12,000 | 0.00 | 0.00 | +0.00 | buy |
| Visionary Wealth Advisors | 0 | 12,000 | +12,000 | 0.00 | 0.00 | +0.00 | buy |
| Stratos Wealth Partners, LTD. | 0 | 10,641 | +10,641 | 0.00 | 0.00 | +0.00 | buy |
| Fountainhead AM, LLC | 10,150 | 10,150 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ROBERTS GLORE & CO INC /IL/ | 10,000 | 10,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CIBC Private Wealth Group LLC | 0 | 10,000 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| Annex Advisory Services, LLC | 10,000 | 10,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Kovack Advisors, Inc. | 10,000 | 10,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| MGO ONE SEVEN LLC | 0 | 10,000 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| Venture Visionary Partners LLC | 0 | 10,000 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| Avalon Trust Co | 7,500 | 7,500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Global Retirement Partners, LLC | 0 | 5,000 | +5,000 | 0.00 | 0.00 | +0.00 | buy |
| NewEdge Advisors, LLC | 4,771 | 4,771 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NATIONAL BANK OF CANADA /FI/ | 4,563 | 4,563 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Gradient Investments LLC | 3,205 | 3,205 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NVWM, LLC | 2,264 | 2,264 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Federation des caisses Desjardins du Quebec | 1,204 | 1,204 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Glen Eagle Advisors, LLC | 1,095 | 1,095 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Westside Investment Management, Inc. | 1,000 | 1,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Allworth Financial LP | 1,000 | 1,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CWM, LLC | 900 | 900 | 0 | 0.00 | 0.00 | 0.00 | hold |
| US BANCORP \DE\ | 0 | 750 | +750 | 0.00 | 0.00 | +0.00 | buy |
| Truvestments Capital LLC | 0 | 600 | +600 | 0.00 | 0.00 | +0.00 | buy |
| CarsonAllaria Wealth Management, Ltd. | 500 | 500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| McIlrath & Eck, LLC | 400 | 400 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CNB Bank | 185 | 185 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CoreCap Advisors, LLC | 0 | 130 | +130 | 0.00 | 0.00 | +0.00 | buy |
| TSFG, LLC | 100 | 100 | 0 | 0.00 | 0.00 | 0.00 | hold |
| CENTRAL TRUST Co | 100 | 100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| HANTZ FINANCIAL SERVICES, INC. | 30 | 30 | 0 | 0.00 | 0.00 | 0.00 | hold |
| Anson Funds Management LP | 8,924,494 | 0 | -8,924,494 | 0.71 | 0.00 | -0.71 | sell |
| Virtu Financial LLC | 175,547 | 0 | -175,547 | 0.01 | 0.00 | -0.01 | sell |
| Connective Capital Management, LLC | 125,000 | 0 | -125,000 | 0.04 | 0.00 | -0.04 | sell |
| Baltimore-Washington Financial Advisors, Inc. | 19,650 | 0 | -19,650 | 0.00 | 0.00 | -0.00 | sell |
| Advisory Services Network, LLC | 200 | 0 | -200 | 0.00 | 0.00 | -0.00 | sell |
| Brookstone Capital Management | 10,030 | 0 | -10,030 | 0.00 | 0.00 | -0.00 | sell |
| Coastal Bridge Advisors, LLC | 30,000 | 0 | -30,000 | 0.00 | 0.00 | -0.00 | sell |
| Connecticut Wealth Management, LLC | 31,731 | 0 | -31,731 | 0.00 | 0.00 | -0.00 | sell |
| Parallel Advisors, LLC | 2,000 | 0 | -2,000 | 0.00 | 0.00 | -0.00 | sell |
| Qube Research & Technologies Ltd | 221,660 | 0 | -221,660 | 0.00 | 0.00 | -0.00 | sell |
| NICOLET ADVISORY SERVICES, LLC | 15,950 | 0 | -15,950 | 0.00 | 0.00 | -0.00 | sell |