| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Deep Track Capital, LP | 0 | 1,529,987 | +1,529,987 | 0.00 | 0.43 | +0.43 | buy |
| Rosalind Advisors, Inc. | 19,300,000 | 1,075,105 | -18,224,895 | 4.14 | 6.34 | +2.21 | sell |
| SPHERA FUNDS MANAGEMENT LTD. | 0 | 933,225 | +933,225 | 0.00 | 1.36 | +1.36 | buy |
| Avidity Partners Management LP | 0 | 918,000 | +918,000 | 0.00 | 0.42 | +0.42 | buy |
| Logos Global Management LP | 0 | 600,000 | +600,000 | 0.00 | 0.60 | +0.60 | buy |
| Octagon Capital Advisors LP | 0 | 489,596 | +489,596 | 0.00 | 0.70 | +0.70 | buy |
| TANG CAPITAL MANAGEMENT LLC | 0 | 400,000 | +400,000 | 0.00 | 0.25 | +0.25 | buy |
| Ikarian Capital, LLC | 0 | 367,195 | +367,195 | 0.00 | 1.01 | +1.01 | buy |
| Altium Capital Management LLC | 0 | 317,000 | +317,000 | 0.00 | 0.84 | +0.84 | buy |
| PDS Planning, Inc | 0 | 267,580 | +267,580 | 0.00 | 0.21 | +0.21 | buy |
| Alyeska Investment Group, L.P. | 0 | 142,233 | +142,233 | 0.00 | 0.01 | +0.01 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 0 | 97,636 | +97,636 | 0.00 | 0.03 | +0.03 | buy |
| AdvisorShares Investments LLC | 0 | 49,084 | +49,084 | 0.00 | 0.08 | +0.08 | buy |
| Fore Capital, LLC | 0 | 18,421 | +18,421 | 0.00 | 0.32 | +0.32 | buy |
| TD Waterhouse Canada Inc. | 0 | 2,753 | +2,753 | 0.00 | 0.00 | +0.00 | buy |
| IAG Wealth Partners, LLC | 0 | 2,750 | +2,750 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 0 | 1,652 | +1,652 | 0.00 | 0.00 | +0.00 | buy |
| Crewe Advisors LLC | 0 | 956 | +956 | 0.00 | 0.00 | +0.00 | buy |
| Global Wealth Strategies & Associates | 0 | 526 | +526 | 0.00 | 0.00 | +0.00 | buy |
| NATIONAL BANK OF CANADA /FI/ | 0 | 214 | +214 | 0.00 | 0.00 | +0.00 | buy |
| Avalon Trust Co | 0 | 197 | +197 | 0.00 | 0.00 | +0.00 | buy |
| NewEdge Advisors, LLC | 0 | 124 | +124 | 0.00 | 0.00 | +0.00 | buy |
| NVWM, LLC | 0 | 59 | +59 | 0.00 | 0.00 | +0.00 | buy |
| FNY Investment Advisers, LLC | 0 | 39 | +39 | 0.00 | 0.00 | 0.00 | buy |
| Federation des caisses Desjardins du Quebec | 0 | 31 | +31 | 0.00 | 0.00 | +0.00 | buy |
| Glen Eagle Advisors, LLC | 0 | 28 | +28 | 0.00 | 0.00 | +0.00 | buy |
| Westside Investment Management, Inc. | 0 | 26 | +26 | 0.00 | 0.00 | +0.00 | buy |
| Allworth Financial LP | 0 | 26 | +26 | 0.00 | 0.00 | +0.00 | buy |
| CENTRAL TRUST Co | 0 | 26 | +26 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 0 | 23 | +23 | 0.00 | 0.00 | 0.00 | buy |
| CarsonAllaria Wealth Management, Ltd. | 0 | 13 | +13 | 0.00 | 0.00 | +0.00 | buy |
| McIlrath & Eck, LLC | 0 | 10 | +10 | 0.00 | 0.00 | +0.00 | buy |
| MOTCO | 0 | 4 | +4 | 0.00 | 0.00 | +0.00 | buy |
| CoreCap Advisors, LLC | 0 | 3 | +3 | 0.00 | 0.00 | +0.00 | buy |
| TSFG, LLC | 0 | 2 | +2 | 0.00 | 0.00 | 0.00 | buy |
| ROBERTS GLORE & CO INC /IL/ | 10,000 | 0 | -10,000 | 0.00 | 0.00 | -0.00 | sell |
| HANTZ FINANCIAL SERVICES, INC. | 30 | 0 | -30 | 0.00 | 0.00 | 0.00 | sell |
| MONETA GROUP INVESTMENT ADVISORS LLC | 108,481 | 0 | -108,481 | 0.00 | 0.00 | -0.00 | sell |
| WEDBUSH SECURITIES INC | 65,500 | 0 | -65,500 | 0.00 | 0.00 | -0.00 | sell |
| MOTCO | 185 | 0 | -185 | 0.00 | 0.00 | -0.00 | sell |
| RA CAPITAL MANAGEMENT, L.P. | 44,004,464 | 0 | -44,004,464 | 0.16 | 0.00 | -0.16 | sell |
| Rathbones Group PLC | 65,381 | 0 | -65,381 | 0.00 | 0.00 | -0.00 | sell |
| Mariner, LLC | 13,650 | 0 | -13,650 | 0.00 | 0.00 | -0.00 | sell |
| LPL Financial LLC | 45,000 | 0 | -45,000 | 0.00 | 0.00 | -0.00 | sell |
| CIBC WORLD MARKET INC. | 207,395 | 0 | -207,395 | 0.00 | 0.00 | -0.00 | sell |
| AdvisorShares Investments LLC | 1,865,217 | 0 | -1,865,217 | 0.09 | 0.00 | -0.09 | sell |
| Alyeska Investment Group, L.P. | 5,404,861 | 0 | -5,404,861 | 0.01 | 0.00 | -0.01 | sell |
| HighTower Advisors, LLC | 14,808 | 0 | -14,808 | 0.00 | 0.00 | -0.00 | sell |
| YHB Investment Advisors, Inc. | 50,000 | 0 | -50,000 | 0.00 | 0.00 | -0.00 | sell |
| SPHERA FUNDS MANAGEMENT LTD. | 25,581,395 | 0 | -25,581,395 | 1.13 | 0.00 | -1.13 | sell |
| Virtu Financial LLC | 117,750 | 0 | -117,750 | 0.00 | 0.00 | -0.00 | sell |
| CWM, LLC | 900 | 0 | -900 | 0.00 | 0.00 | 0.00 | sell |
| Westside Investment Management, Inc. | 1,000 | 0 | -1,000 | 0.00 | 0.00 | -0.00 | sell |
| Creative Planning | 18,251 | 0 | -18,251 | 0.00 | 0.00 | -0.00 | sell |
| Nadler Financial Group, Inc. | 98,700 | 0 | -98,700 | 0.00 | 0.00 | -0.00 | sell |
| Gradient Investments LLC | 3,205 | 0 | -3,205 | 0.00 | 0.00 | -0.00 | sell |
| Annex Advisory Services, LLC | 10,000 | 0 | -10,000 | 0.00 | 0.00 | -0.00 | sell |
| RWA WEALTH PARTNERS, LLC | 75,617 | 0 | -75,617 | 0.00 | 0.00 | -0.00 | sell |
| BOOTHBAY FUND MANAGEMENT, LLC | 4,220,899 | 0 | -4,220,899 | 0.03 | 0.00 | -0.03 | sell |
| Allworth Financial LP | 1,000 | 0 | -1,000 | 0.00 | 0.00 | -0.00 | sell |
| Baltimore-Washington Financial Advisors, Inc. | 19,650 | 0 | -19,650 | 0.00 | 0.00 | -0.00 | sell |
| Cerity Partners LLC | 63,271 | 0 | -63,271 | 0.00 | 0.00 | -0.00 | sell |
| Formidable Asset Management, LLC | 127,380 | 0 | -127,380 | 0.01 | 0.00 | -0.01 | sell |
| Stratos Wealth Partners, LTD. | 16,641 | 0 | -16,641 | 0.00 | 0.00 | -0.00 | sell |
| NewEdge Advisors, LLC | 4,771 | 0 | -4,771 | 0.00 | 0.00 | -0.00 | sell |
| NVWM, LLC | 2,264 | 0 | -2,264 | 0.00 | 0.00 | -0.00 | sell |
| McIlrath & Eck, LLC | 400 | 0 | -400 | 0.00 | 0.00 | -0.00 | sell |
| Conservest Capital Advisors, Inc. | 33,500 | 0 | -33,500 | 0.00 | 0.00 | -0.00 | sell |
| Kovack Advisors, Inc. | 10,000 | 0 | -10,000 | 0.00 | 0.00 | -0.00 | sell |
| X-Square Capital, LLC | 42,000 | 0 | -42,000 | 0.01 | 0.00 | -0.01 | sell |
| Crewe Advisors LLC | 36,363 | 0 | -36,363 | 0.00 | 0.00 | -0.00 | sell |
| MGO ONE SEVEN LLC | 10,000 | 0 | -10,000 | 0.00 | 0.00 | -0.00 | sell |
| CNB Bank | 185 | 0 | -185 | 0.00 | 0.00 | -0.00 | sell |
| Integrated Wealth Concepts LLC | 77,075 | 0 | -77,075 | 0.00 | 0.00 | -0.00 | sell |
| FNY Investment Advisers, LLC | 419,135 | 0 | -419,135 | 0.08 | 0.00 | -0.08 | sell |
| Altium Capital Management LLC | 13,953,488 | 0 | -13,953,488 | 1.56 | 0.00 | -1.56 | sell |
| Cresset Asset Management, LLC | 10,000 | 0 | -10,000 | 0.00 | 0.00 | -0.00 | sell |
| HHLR ADVISORS, LTD. | 2,457,542 | 0 | -2,457,542 | 0.02 | 0.00 | -0.02 | sell |
| CRA Financial Services, LLC | 39,760 | 0 | -39,760 | 0.00 | 0.00 | -0.00 | sell |
| Strategic Blueprint, LLC | 32,000 | 0 | -32,000 | 0.00 | 0.00 | -0.00 | sell |
| Ikarian Capital, LLC | 13,953,488 | 0 | -13,953,488 | 1.18 | 0.00 | -1.18 | sell |
| Avidity Partners Management LP | 34,884,000 | 0 | -34,884,000 | 0.40 | 0.00 | -0.40 | sell |
| Logos Global Management LP | 40,000,000 | 0 | -40,000,000 | 1.25 | 0.00 | -1.25 | sell |
| Venture Visionary Partners LLC | 15,727 | 0 | -15,727 | 0.00 | 0.00 | -0.00 | sell |
| EVOKE WEALTH, LLC | 25,000 | 0 | -25,000 | 0.01 | 0.00 | -0.01 | sell |
| Avalon Trust Co | 7,500 | 0 | -7,500 | 0.00 | 0.00 | -0.00 | sell |
| TSFG, LLC | 100 | 0 | -100 | 0.00 | 0.00 | 0.00 | sell |
| Powell Investment Advisors, LLC | 60,000 | 0 | -60,000 | 0.01 | 0.00 | -0.01 | sell |
| Visionary Wealth Advisors | 12,000 | 0 | -12,000 | 0.00 | 0.00 | -0.00 | sell |
| IAG Wealth Partners, LLC | 104,513 | 0 | -104,513 | 0.01 | 0.00 | -0.01 | sell |
| Kestra Advisory Services, LLC | 28,286 | 0 | -28,286 | 0.00 | 0.00 | -0.00 | sell |
| Legacy Financial Group LLC | 22,666 | 0 | -22,666 | 0.00 | 0.00 | -0.00 | sell |
| Octagon Capital Advisors LP | 18,604,650 | 0 | -18,604,650 | 0.83 | 0.00 | -0.83 | sell |
| Simplify Asset Management Inc. | 500,000 | 0 | -500,000 | 0.01 | 0.00 | -0.01 | sell |
| Thrive Wealth Management, LLC | 28,000 | 0 | -28,000 | 0.00 | 0.00 | -0.00 | sell |
| Deep Track Capital, LP | 58,139,535 | 0 | -58,139,535 | 0.47 | 0.00 | -0.47 | sell |
| Riverwater Partners LLC | 20,190 | 0 | -20,190 | 0.00 | 0.00 | -0.00 | sell |
| CarsonAllaria Wealth Management, Ltd. | 500 | 0 | -500 | 0.00 | 0.00 | -0.00 | sell |
| CoreCap Advisors, LLC | 130 | 0 | -130 | 0.00 | 0.00 | -0.00 | sell |
| CARDIFF PARK ADVISORS, LLC | 35,000 | 0 | -35,000 | 0.00 | 0.00 | -0.00 | sell |