| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BVF INC/IL | 802,102 | 1,110,002 | +307,900 | 0.19 | 0.18 | -0.01 | buy |
| Blue Owl Capital Holdings LP | 823,785 | 959,337 | +135,552 | 1.75 | 1.29 | -0.47 | buy |
| Cable Car Capital, LP | 643,933 | 754,749 | +110,816 | 0.28 | 1.30 | +1.03 | buy |
| Omega Fund Management, LLC | 455,361 | 455,361 | 0 | 1.10 | 1.40 | +0.30 | hold |
| ORBIMED ADVISORS LLC | 378,556 | 378,556 | 0 | 0.05 | 0.04 | -0.01 | hold |
| RTW INVESTMENTS, LP | 334,445 | 334,445 | 0 | 0.02 | 0.02 | -0.01 | hold |
| BML Capital Management, LLC | 177,026 | 200,730 | +23,704 | 1.08 | 0.65 | -0.44 | buy |
| BlackRock, Inc. | 131,587 | 129,214 | -2,373 | 0.00 | 0.00 | -0.00 | sell |
| CITADEL ADVISORS LLC | 86,478 | 124,345 | +37,867 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 66,096 | 81,696 | +15,600 | 0.00 | 0.00 | -0.00 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 66,666 | 66,666 | 0 | 0.00 | 0.00 | -0.00 | hold |
| GEODE CAPITAL MANAGEMENT, LLC | 54,146 | 59,929 | +5,783 | 0.00 | 0.00 | -0.00 | buy |
| NEA Management Company, LLC | 50,005 | 50,005 | 0 | 0.02 | 0.01 | -0.00 | hold |
| HSBC HOLDINGS PLC | 34,228 | 34,884 | +656 | 0.00 | 0.00 | -0.00 | buy |
| Rangeley Capital, LLC | 18,244 | 32,590 | +14,346 | 0.11 | 0.18 | +0.07 | buy |
| Sofinnova Investments, Inc. | 31,884 | 31,884 | 0 | 0.01 | 0.01 | -0.00 | hold |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 18,727 | 26,663 | +7,936 | 0.00 | 0.00 | +0.00 | buy |
| Shay Capital LLC | 23,216 | 19,130 | -4,086 | 0.03 | 0.01 | -0.01 | sell |
| Aldebaran Capital, LLC | 19,070 | 18,566 | -504 | 0.12 | 0.07 | -0.05 | sell |
| XTX Topco Ltd | 12,177 | 15,112 | +2,935 | 0.00 | 0.00 | -0.00 | buy |
| HRT FINANCIAL LP | 0 | 13,909 | +13,909 | 0.00 | 0.00 | +0.00 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 13,495 | 12,990 | -505 | 0.01 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 10,797 | 10,959 | +162 | 0.00 | 0.00 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 0 | 1,011 | +1,011 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 0 | 224 | +224 | 0.00 | 0.00 | +0.00 | buy |
| NewEdge Advisors, LLC | 491 | 160 | -331 | 0.00 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 24 | 24 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Caitong International Asset Management Co., Ltd | 0 | 2 | +2 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 11,454 | 0 | -11,454 | 0.00 | 0.00 | -0.00 | sell |
| DRW Securities, LLC | 43,768 | 0 | -43,768 | 0.02 | 0.00 | -0.02 | sell |
| Monashee Investment Management LLC | 91,621 | 0 | -91,621 | 0.36 | 0.00 | -0.36 | sell |
| Squarepoint Ops LLC | 48,237 | 0 | -48,237 | 0.00 | 0.00 | -0.00 | sell |
| Avion Wealth | 57 | 0 | -57 | 0.00 | 0.00 | 0.00 | sell |
| Fortitude Family Office, LLC | 400 | 0 | -400 | 0.00 | 0.00 | -0.00 | sell |