| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Cable Car Capital, LP | 0 | 643,933 | +643,933 | 0.00 | 0.28 | +0.28 | buy |
| Blue Owl Capital Holdings LP | 540,924 | 823,785 | +282,861 | 1.37 | 1.75 | +0.39 | buy |
| Monashee Investment Management LLC | 0 | 91,621 | +91,621 | 0.00 | 0.36 | +0.36 | buy |
| BlackRock, Inc. | 52,111 | 131,587 | +79,476 | 0.00 | 0.00 | +0.00 | buy |
| DRW Securities, LLC | 0 | 43,768 | +43,768 | 0.00 | 0.02 | +0.02 | buy |
| HSBC HOLDINGS PLC | 0 | 34,228 | +34,228 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 37,378 | 66,096 | +28,718 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 24,170 | 48,237 | +24,067 | 0.00 | 0.00 | +0.00 | buy |
| Shay Capital LLC | 0 | 23,216 | +23,216 | 0.00 | 0.03 | +0.03 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 0 | 13,495 | +13,495 | 0.00 | 0.01 | +0.01 | buy |
| MILLENNIUM MANAGEMENT LLC | 0 | 11,454 | +11,454 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 3,987 | 10,797 | +6,810 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 47,688 | 54,146 | +6,458 | 0.00 | 0.00 | -0.00 | buy |
| VANGUARD GROUP INC | 233,358 | 238,000 | +4,642 | 0.00 | 0.00 | -0.00 | buy |
| Rangeley Capital, LLC | 15,000 | 18,244 | +3,244 | 0.11 | 0.11 | -0.01 | buy |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 17,708 | 18,727 | +1,019 | 0.00 | 0.00 | -0.00 | buy |
| Fortitude Family Office, LLC | 0 | 400 | +400 | 0.00 | 0.00 | +0.00 | buy |
| Avion Wealth | 0 | 57 | +57 | 0.00 | 0.00 | 0.00 | buy |
| ORBIMED ADVISORS LLC | 378,556 | 378,556 | 0 | 0.07 | 0.05 | -0.02 | hold |
| BVF INC/IL | 802,102 | 802,102 | 0 | 0.26 | 0.19 | -0.08 | hold |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 66,666 | 66,666 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BNP PARIBAS FINANCIAL MARKETS | 24 | 24 | 0 | 0.00 | 0.00 | -0.00 | hold |
| RTW INVESTMENTS, LP | 334,445 | 334,445 | 0 | 0.03 | 0.02 | -0.01 | hold |
| NEA Management Company, LLC | 50,005 | 50,005 | 0 | 0.02 | 0.02 | -0.00 | hold |
| Sofinnova Investments, Inc. | 31,884 | 31,884 | 0 | 0.02 | 0.01 | -0.01 | hold |
| Omega Fund Management, LLC | 455,361 | 455,361 | 0 | 1.67 | 1.10 | -0.57 | hold |
| FEDERATED HERMES, INC. | 204 | 0 | -204 | 0.00 | 0.00 | -0.00 | sell |
| Aldebaran Capital, LLC | 19,562 | 19,070 | -492 | 0.15 | 0.12 | -0.03 | sell |
| Tower Research Capital LLC (TRC) | 877 | 0 | -877 | 0.00 | 0.00 | -0.00 | sell |
| BML Capital Management, LLC | 182,509 | 177,026 | -5,483 | 1.37 | 1.08 | -0.29 | sell |
| NewEdge Advisors, LLC | 12,960 | 491 | -12,469 | 0.00 | 0.00 | -0.00 | sell |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 12,774 | 0 | -12,774 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 44,951 | 12,177 | -32,774 | 0.00 | 0.00 | +0.00 | sell |
| CITADEL ADVISORS LLC | 122,247 | 86,478 | -35,769 | 0.00 | 0.00 | -0.00 | sell |
| Atlas Venture Life Science Advisors, LLC | 377,814 | 0 | -377,814 | 0.41 | 0.00 | -0.41 | sell |
| Deep Track Capital, LP | 878,516 | 0 | -878,516 | 0.20 | 0.00 | -0.20 | sell |