| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Frazier Life Sciences Management, L.P. | 2,291,666 | 2,291,666 | 0 | 0.54 | 0.37 | -0.17 | hold |
| Novo Holdings A/S | 2,305,000 | 1,057,421 | -1,247,579 | 1.58 | 0.54 | -1.04 | sell |
| GENERAL AMERICAN INVESTORS CO INC | 354,361 | 354,361 | 0 | 0.19 | 0.15 | -0.05 | hold |
| WELLS FARGO & COMPANY/MN | 123,463 | 78,029 | -45,434 | 0.00 | 0.00 | -0.00 | sell |
| IRONWOOD INVESTMENT MANAGEMENT LLC | 25,135 | 25,135 | 0 | 0.09 | 0.07 | -0.03 | hold |
| HRT FINANCIAL LP | 0 | 20,847 | +20,847 | 0.00 | 0.00 | +0.00 | buy |
| OLD MISSION CAPITAL LLC | 0 | 13,759 | +13,759 | 0.00 | 0.00 | +0.00 | buy |
| VSM Wealth Advisory, LLC | 0 | 10,000 | +10,000 | 0.00 | 0.02 | +0.02 | buy |
| China Universal Asset Management Co., Ltd. | 5,000 | 5,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| RHUMBLINE ADVISERS | 1,763 | 1,793 | +30 | 0.00 | 0.00 | -0.00 | buy |
| GAMMA Investing LLC | 1,857 | 1,426 | -431 | 0.00 | 0.00 | -0.00 | sell |
| Steigerwald, Gordon & Koch Inc. | 0 | 1,250 | +1,250 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 0 | 200 | +200 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 98 | 91 | -7 | 0.00 | 0.00 | -0.00 | sell |
| Clearstead Advisors, LLC | 48 | 48 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Smartleaf Asset Management LLC | 43 | 43 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Activest Wealth Management | 1 | 1 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Allworth Financial LP | 7 | 0 | -7 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 10,634 | 0 | -10,634 | 0.00 | 0.00 | -0.00 | sell |